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Defect in Biological Technology

Rapid heating prepares energy-saving zeolite for greater role in industrial separations

... its results in an article titled "Grain Boundary defect Elimination in a Zeolite Membrane by Rapid ... shows us the nonselective pathways and other defect features within the membrane," says Snyder. ... in conventionally treated membranes, very few defect features were identified in the RTP-treated ....

New filter clears up fiber optic communications

... system or material that can confine and direct electromagnetic waves.) A defect cavity is located one unit cell above the waveguide layer. The waveguides ... to make these controlled structures with one input, another output and a defect . that definitely takes some work. A future direction is to simplify the ...

Discovery of new cause of mental retardation simplifies search for treatments

... the DNA. When the cause is genetic (hereditary), identifying the precise defect is crucial for the patients medical support or for assessing the risk of having children. Scientists estimate that, in about 30% of the patients, a defect on the X-chromosome is the underlying cause. This is called X-linked ...

BioMarin Licenses Technology From Leading Cystic Fibrosis Research Laboratory at the University of California, San Francisco

... Molecular Chaperones Target Underlying defect in Cystic Fibrosis; CFTR Folding and Transport ... there is no therapeutic approved that addresses the underlying molecular defect in cystic fibrosis, and most patients succumb to respiratory failure as ...

Bilayer graphene gets a bandgap

... transmission. "The problem with transport measurements is that they are too sensitive to defects," says Wang. "A tiny amount of impurity or defect doping can create a big change in the resistance of the graphene and mask the intrinsic behavior of the material. That's why we decided to go with ...

ViroPharma Receives Complete Response Letter for Cinryze(TM) Supplemental Biologics License Application for Acute Treatment of Hereditary Angioedema

... debilitating, life-threatening genetic disorder caused by a deficiency of C1 inhibitor, a human plasma protein. This condition is the result of a defect in the gene controlling the synthesis of C1 inhibitor. C1 inhibitor maintains the natural regulation of the contact, complement, and fibrinolytic ...

ViroPharma Incorporated Honored by the National Organization for Rare Disorders

... debilitating, life-threatening genetic disorder caused by a deficiency of C1 inhibitor, a human plasma protein. This condition is the result of a defect in the gene controlling the synthesis of C1 inhibitor. C1 inhibitor maintains the natural regulation of the contact, complement, and fibrinolytic ...

The Journal of Cardiac Failure Publishes Results From Celladon Corporation's First-in-Human Phase 1/2 Clinical Trial in Advanced Heart Failure

... MYDICAR is designed to restore levels of an enzyme, SERCA2a, known to play a key role in the progression of heart failure. Repairing this molecular defect in animal studies has been shown to reverse the disease and restore cardiac function. "Despite important therapeutic advances in pharmacologic ...

Video: Accera Launches Axona(TM), First Medical Food Therapy to Help Manage Mild-to-Moderate Alzheimer's Disease

... by a substantial decrease in the brain's ability to metabolize glucose, which is the brain's primary source of energy. Known as hypometabolism, this defect may contribute to both the clinical and pathological course of the disease. Axona targets the metabolic defects of glucose utilization in the brain ...

Biomerix Corporation Announces FDA Clearance and Market Launch of REVIVE(TM) for Use in Soft Tissue Repair Procedures

... can lead to persistent groin pain in 30% of patients at one year(2). Clinical feedback has confirmed REVIVE offers excellent conformability to the defect and ease of handling.(3) "Biomerix is poised for rapid growth over the course of the next few years. The company plans to launch numerous ...

Gene Therapy Field Advances With Important Clinical Findings Reported in the New England Journal of Medicine

... of the immune system. The infant children studied had a rare form of severe combined immunodeficiency (SCID). SCID arises in infants with a genetic defect that leaves them unable to produce an enzyme called adenosine deaminase. This key enzyme is most active in lymphocytes, which are white blood cells ...

Asbestos, Pharmaceutical Liability, Construction Defects, Nanotech: Covered by Targeted CLE Teleconferences

... & More. February 24 - Defense Perspectives on Attorney General Pharmaceutical Claims. February 24 - Construction defect Litigation: Delay, Disruption, Collection Claims in Foreclosure & Contract Disputes. February 26 - International Asbestos Litigation. ...

Pigs bred with cystic fibrosis provide model to mimic human disease

... Prather collaborated with Michael Welsh from the Howard Hughes Medical Institute at the University of Iowa. To create the genetic defect in pigs, a team led by Welsh made genetic modifications in pig cells. Prather's group then generated the genetically modified pigs from the cells ...

Cardica Receives $1 Million Milestone Payment From Cook Medical for Development of Heart Defect Closure Device

... development of a specialized automated device used to close holes in the heart known as patent foramen ovales (PFO), a relatively common heart defect present in 15 to 20 percent of the general population. "Patients with PFO may be at increased risk for several serious medical conditions, ...

Acologix Presents Preclinical Data on Cartilage Regeneration by AC-100 at the 30th ASBMR Annual Meeting

... into the operated knee joint. Cartilage regeneration was evaluated after three and six months. In another study, a more superficial knee cartilage defect that did not reach the bone was treated with four weekly intra-articular injections of AC-100 or placebo. In half of the goats in each group, ...

Repligen Receives Research Grants to Support Friedreich's Ataxia Development Program

... the program matures and we prepare for human clinical trials." Friedreich's ataxia is an inherited neurodegenerative disease in which a single gene defect results in inadequate production of the protein frataxin, leading to progressive damage to the nervous system and loss of muscle function. Prior ...

ViroPharma To Acquire Lev Pharmaceuticals

... complete response submission for Cinryze targeting an action date of October 14, 2008. About Hereditary Angioedema HAE is the result of a defect in the gene controlling the synthesis of C1 inhibitor. C1 inhibitor maintains the natural regulation of the contact, complement, and fibrinolytic ...

Cystic Fibrosis - Axentis Pharma Takes Over Patents and Continues Development of Innovative Platform Technology

... designed to regulate the concentration of salt in the epithelial cells of the lungs and other organs. In patients with cystic fibrosis, a genetic defect means that many such proteins are produced with minor structural mutations. Although the mutated proteins still offer sufficient functionality, they ...

Perfecting a solar cell by adding imperfections

... films might be used in fuel cells and batteries as well. "This study is an example of using nanostructuring of materials changing things like defect density and tube length at very small scales to shift trade-offs between materials properties and get more performance out of a given material," ...

Raptor Pharmaceuticals Corp. Receives FDA Orphan Drug Designation for Cysteamine in Huntington's Disease

... every 20,000 people resulting in around 20,000 patients in the U.S. presently. There is currently no drug available that targets the unique molecular defect that is believed to cause HD, a progressive disease that often leads to death within 15 to 20 years after diagnosis. HD is caused by a defective gene ...

PTC124 Featured at Third Annual Congress of Myology

... caused by genetic alterations, known as mutations. By targeting a specific type of genetic alteration -- nonsense mutations -- PTC124 bypasses the defect and leads to the restoration of a functional protein. The company has catalogued over 2,400 distinct genetic disorders for which nonsense mutations ...

AMT's Cooperative Research and Development Agreement With NIH to Boost Production Capacity

... with La Sapienza University in Rome, Italy, since this indication requires a relatively high dose of gene therapy vector in order to correct the defect in all affected muscles. Ronald Lorijn, CEO of AMT said: "This CRADA with the NIH provides AMT with a technology that in combination with our ...

Spiraling nanotrees offer new twist on growth of nanowires

... also elongate in this way, growth of the trunks is driven by a screw dislocation, or defect, in their crystal structure. At the top of the trunk, the defect provides a spiral step for atoms to settle on an otherwise perfect crystal face, causing them stack together in a spiral parking ramp-type structure ...

NIST micro sensor and micro fridge make cool pair

... the second stage of cooling from 300mK down to the operating temperature (100 mK). One promising application is cheaper, simpler semiconductor defect analysis using X-rays. A small company is already commercializing an earlier version of TES technology for this purpose. In another application, ...

Copolymers block out new approaches to microelectronics at NIST

... on templates lined with troughs separated by crests.2 When a heated zone is swept across the template, the polymer molecules assemble into almost defect free, well-aligned lines faster over the entire template, an important feature for nanotech manufacturing applications.3 Sangcheol Kim (working with ...

Avicena's HD-02 to Proceed to NIH Sponsored Phase III Huntington's Disease Trial

... Huntington's disease is a progressive neurodegenerative disease caused by a defective gene that is often inherited from parent to child. This genetic defect causes a widespread deterioration of neurons in those parts of the brain that are responsible for controlling cognitive, emotional and motor ...

AGA Medical Corporation Receives European CE Mark Approval for the AMPLATZER(R) Duct Occluder II

... The ADO II expands the AGA family of occlusion devices designed to occlude or close a patent ductus arteriosus ("PDA"), a type of congenital heart defect that occurs when a blood vessel called the ductus arteriosus fails to close after birth, as it normally should. "We believe the new ADO II ...

Historic Breakthrough in Fighting Children's Batten Disease as China Stem Cells Give New Lease on Life to 6 Year Old California Boy

... Disease, it is the most common form of a group of disorders called Neuronal Ceroid Lipofuscinoses, or NCLs. Due to a genetic defect at birth, over time those with NCL suffer progressive nervous system breakdown leading to mental impairment, worsening seizures, increasing loss of ...

mNEMOSCIENCE GmbH Announces Global Licensing Agreement With Aporo Biomedical

... The Company's initial area of focus is structural heart disease, including trans-catheter treatment of patent foramen ovale (PFO) and atrial septal defect (ASD). For more information, visit http://www.aporobiomedical.com . Forward-Looking Safe Harbor Statement With the exception of historical ...

'High Q' NIST nanowires may be practical oscillators

... Kris Bertness, who grew the nanowires. NIST has developed a unique way of growing hexagonal gallium nitride (GaN) nanowires featuring low defect density and high luminescence intensity. In a new paper*, researchers at NIST and the University of Colorado at Boulder report high Q factors in ...

European EMEA Acceptance of Marketing Authorization Application Filing for SNT-MC17 in Friedreich's Ataxia by Santhera

... North America and Europe. Average life expectancy for FRDA patients is limited to approximately 35 to 50 years. The disorder results from a genetic defect in the gene encoding for frataxin. Reduced levels of this protein ultimately result in impaired energy production in mitochondria, the cells' energy ...

Camtronics Receives Health IT Awards

... Frost & Sullivan closely monitors the products and R&D projects of all market participants, and considers numerous other criteria such as lowest defect percentage per batch of units produced and the product's ability to fulfill customer needs, as part of the selection process. Their analysts ...

UW-Madison scientists find a key to cell division

... cycle would be crucial elements in understanding how the process works." The next step was to inactivate each protein in a developing embryo. If a defect occurred, it would mean that the inactivated protein is essential for normal development. "We used nematodes, which are small roundworms that are ...

Part 5 Project Performance Get on the path to continuous improvement

... is more important than crisis recovery. Accept continuous improvement as a way of life. The next article will explore the 6 Sigma and what defect prevention has to do with project management. ...

Human cloning plans get blessing from British government

... replace it with the nucleus of a cell from a familial MND patient. Eggs that have successfully received the nucleus containing the MND-causing gene defect will be encouraged to grow up to the 200-cell stage. The embryonic stem cells will be removed, grown and directed to become motor neurons using a ...

Exec focuses on blogs as business tool

... businesses, Gibler said, because they encourage the hive behavior that advertisers thrive on. In the blog community, information as diverse as a key defect in bicycle locks and a remixed online cartoon can spread through a word-of-mouth effort unmatched in other mediums. Businesses such as General ...

Milwaukee area biotech ZyStor seeks more funding

... how rare they are," Peterson said. To be effective, the therapeutic enzyme must be delivered to the appropriate cells in tissues where the storage defect manifests itself. The problem with existing enzyme therapy treatments is that too few of the therapeutic enzymes infused into patients are delivered ...

Are there more Enrons out there?

... to a cell-block of inmates? Did its demise result solely from the moral and ethical failures of its leaders? Or was its collapse also caused by a defect in the corporate American business system which causes some organizations to push the ethos of individual achievement and financial self-interest too ...

Mirus granted European patent for gene therapy

... also known as amyotrophic lateral sclerosis. Patients with the most common muscular dystrophies, Duchenne and Becker, suffer from a genetic defect in which dystrophin protein is either poor or inadequate in their muscle cells. It affects roughly one of every 3,500 male births, according to ....
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