Navigation Links
Concentration in Biological Technology

Halozyme Therapeutics Begins Phase 2 Clinical Trial of Insulin With rHuPH20 in Type 1 Diabetic Patients

... be the area under the curve for plasma insulin concentration from zero to 60 minutes after ... additional PK data, as well as blood glucose concentration at various time points. Safety data such as ... insulin absorption and a shorter time to peak concentration when compared to Humalog alone. Results ( ...

Highest Replikin Concentrations and Cyclical Behavior Related to Human Mortality Are Found in Malaria Trypanosomes

... between 1986 and 2007. The quantitative replikin concentration (Replikin Count(TM) = number of replikins per 100 ... mortality. Cyclic increases in replikin concentration in the genome can be a mechanism of expansion of ... into a territory. In other examples, the replikin concentration of West Nile Virus was earlier found to increase ...

ANX-530 Demonstrates Equivalent Pharmacokinetics to Navelbine(R) in a Registrational Bioequivalence Clinical Study

... in the body over time. Cmax is the maximum concentration of the drug measured in the blood at any given ... 80-125% Cmax: Maximum plasma concentration AUClast: Area under the plasma concentration time curve from time zero to the last ...

Baxter to Launch GARDian(TM), a Groundbreaking Initiative That Helps Provide Continued Access to GAMMAGARD for Current Patients

... should be administered at the minimum concentration available and the minimum rate of infusion ... should be administered at the minimum concentration available and the minimum rate of infusion ... should be administered at the minimum concentration available and the minimum rate of infusion ...

Five Questions About Protopic (tacrolimus) Ointment

... Protopic is available in two concentrations: 0.1% and 0.03%. Either concentration can be used in adults, while only the 0.03% concentration is indicated for children between the ages of 2 and 15. Protopic should ...

Tobira Therapeutics Inc. Announces Phase I Data Demonstrating Pharmacokinetic Properties of TAK-652 for the Treatment of HIV

... relatively good oral bioavailability (as shown by the plasma TBR-652 concentration data) and has a long plasma half-life of TBR-652 (approximate mean of 35 ... TBR-652 plasma concentrations were well above the predicted target plasma concentration (2ng/mL) with or without food. In both studies TBR-652 was safe and well ...

Data Presented at Society of Nuclear Medicine 2009 Annual Meeting Supports Potential of Peregrine's Cotara(R) for the Treatment of Brain Cancer

... show that in patients dosed in the first two cohorts of the study, the concentration of Cotara in brain tumors was on average more than 300-fold higher than in ... the University of Alabama at Birmingham , and his colleagues assessed the concentration of Cotara in GBM patients' tumors and in their healthy brain tissue, as ...

AFFiRiS AG: Atherosclerosis Vaccine Development Receives EU Support

... Statins act on low density lipoprotein cholesterol (LDLc) and reduce its concentration in the blood. This type of treatment can reduce the likelihood of severe ... decreasing the cholesterol transfer from HDL to LDL, thus increasing the concentration of the beneficial HDL. This vaccine approach with its long-lasting effects ...

Microtest Laboratories is an Industry Leader in ICH Stability Testing

... sterility, endotoxins, and particulates. Microtest also checks that the concentration of active ingredients is within specifications, and watch for evidence that real-time or accelerated aging has affected drug concentration or purity. Moreover, Microtest is one of a few labs that offer ...

SemBioSys Genetics Inc. Announces Clinical Results with Plant-Produced Insulin

... insulin for eight hours post-injection (AUC(insulin0to8hrs)); 2) maximum concentration of insulin (Cmax(insulin)); 3) total glucose infused over eight hours ... to Humulin(R) S with respect to total insulin exposure, maximum concentration of insulin and total glucose infused. The only anomalous result from this ...

NeurogesX to Present at 11th Annual BIO CEO & Investor Conference

... product portfolio is led by its product candidate QutenzaTM, a dermal high concentration capsaicin patch designed to manage pain associated with peripheral ... NGX-1998, is a topically applied, liquid formulation containing a high concentration of capsaicin designed to treat pain associated with neuropathic pain ...

A New Way to Predict Outbreaks: Replikin Peptide Concentration in H5N1 Influenza Virus Genome as a Marker for Lethal Outbreaks

... Drs. Bogoch called them "Replikins," and they are strictly defined by the concentration of lysine and histidine residues and the spacing between them. To ... What Replikins have found is that there's a strong correlation between the concentration of replikins and the lethality of an influenza virus outbreak. This allows ...

Paperwork: Buckypapers clarify electrical, optical behavior of nanotubes

... for conductive films is the so-called percolation thresholdessentially the concentration at which random two- or three-dimensional networks of nanotubes first ... follows the percolation theory for ideal two-dimensional sheets, with concentration threshold for conductivity getting lower as the tubes get longer. A sheet ...

Cystic Fibrosis - Axentis Pharma Takes Over Patents and Continues Development of Innovative Platform Technology

... destroys mutated proteins which were originally designed to regulate the concentration of salt in the epithelial cells of the lungs and other organs. In patients ... marker is missing, the protein evades destruction and can regulate the concentration of water and salt secretion in the lung despite its minor structural ...

U.S. Government Accepts $192 Million of sanofi pasteur H5N1 Bulk Vaccine Antigen for Pandemic Stockpile

... for its bulk pandemic vaccine. The dose calculation is based on antigen concentration of seasonal influenza vaccine, which contains 15 mcg per dose. When the dose calculation is based on concentration of sanofi pasteur's licensed pandemic vaccine, which contains 90 mcg per ...

FluForecast(R) Replikin Count(TM) Predicts That the H5N1 Cycle Which Began in 1996 Is Now Over

... A key gene, the Replikin Peak Gene, was found to contain the highest concentration of replikins in the virus genome. In H5N1 reservoirs in chickens, the ... the replikins, specific small peptide constituents of virus proteins whose concentration has been shown to be related quantitatively to rapid replication and ...

Alexza Announces Partnership With Endo for AZ-003 (Staccato(R) fentanyl) in North America

... AZ-003 PK was equivalent to the IV fentanyl PK, with similar peak plasma concentration (Cmax), time to maximum plasma concentration (Tmax), and area under the curve concentration (AUC). These data suggest ...

Novel Alternative Approach to Inhibiting Insulin Growth Factor (IGF) May Provide New Treatment for Breast Cancer and Other Cancers

... proof-of-concept that human monoclonal antibodies (hmAbs) can decrease the concentration of soluble ligands in tumors, suggesting that targeting ligands of growth ... the ligand between the blood and the tumor resulting in a decreased ligand concentration in the tumor. "These data are important because targeting the ligands of ...

Fluid theory confirmed by Foton

... decade. All liquids experience minute fluctuations in temperature or concentration as a result of the different velocities of individual molecules. These ... has also shown that the amplitude of the fluctuations in temperature and concentration greatly increased. It is a rare event when a space mission is able to ...

Scientists discover how cancer may take hold

... enzyme (dubbed IDO) forms molecules called kynurenines. This reduces the concentration of tryptophan in the local tissues and starves T-cells for tryptophan. A ... fork. This system allows the scientists to visually track the location and concentration of certain biochemicals. Our FRET technology with the novel tryptophan ...

NeurogesX Reports Second Quarter 2009 Results

... November 16, 2009. NeurogesX' second most advanced product candidate, NGX-1998, is a topically applied, liquid formulation containing a high concentration of capsaicin designed to treat pain associated with neuropathic pain conditions. NGX-1998 has completed three Phase 1 studies and NeurogesX is ...

ThermoGenesis Announces Expanded Collaboration With Celling Technologies

... In a separate press release today, ThermoGenesis announced the launch of its Res-Q System, an automated cell processing medical device for the concentration of bone marrow-derived stem cells at the point of care. Celling will be the distributor for the Res-Q System in orthopedic applications. ...

Angiotech Pharmaceuticals, Inc. announces financial results for the second quarter ended June 30, 2009

... or slower relative growth, particularly our sales of components to third party medical device manufacturers, which may be impacted by customer concentration and the business issues that certain of our large customers may face, as well as to a more limited extent by economic and credit market conditions. ...

NeurogesX Announces New PDUFA Date for Qutenza(TM) New Drug Application

... November 16, 2009. NeurogesX' second most advanced product candidate, NGX-1998, is a topically applied, liquid formulation containing a high concentration of capsaicin designed to treat pain associated with neuropathic pain conditions. NGX-1998 has completed three Phase 1 studies and NeurogesX is ...

NeurogesX to Hold Conference Call to Discuss Second Quarter 2009 Financial Results

... August 16, 2009. NeurogesX' second most advanced product candidate, NGX-1998, is a topically applied, liquid formulation containing a high concentration of capsaicin designed to treat pain associated with neuropathic pain conditions. NGX-1998 has completed three Phase 1 studies and NeurogesX is ...

Improving Transfusion Safety: Fenwal, Verax Biomedical Sign Agreement for Rapid, Point-of-Care Bacteria Test

... For more information, please visit www.fenwalinc.com . (i.) Benjamin R. and Wagner S. The residual risk of sepsis: modeling the effect of concentration on bacterial detection in 2-bottle culture systems and estimation of false-negative culture rates. Transfusion 2007; 47:1381-1389. ...

NeurogesX Added to Russell 3000 Index

... of August 16, 2009. NeurogesX' second most advanced product candidate, NGX-1998, is a topically applied, liquid formulation containing a high concentration of capsaicin designed to treat pain associated with neuropathic pain conditions. NGX-1998 has completed three Phase 1 studies and NeurogesX is ...

Innocoll Announces Provisional Findings From Its Three Phase 2 Clinical Trials Investigating CollaRx(R) GENTAMICIN TOPICAL for the Treatment and Prevention of Diabetic Foot Infections

... aminoglycoside antibiotic with a concentration-dependent mechanism of action, for local action at the wound site. This technology achieves a high concentration of drug at the target tissue, while maintaining low systemic levels well below the toxicity threshold. The product concept and technology is featured ...

Lethality of H1N1 Influenza Virus Increasing According to Latest Analysis of Virus Peptide Genomic Data

... and predictive tools are based on the company's discovery of a new group of peptides related to rapid replication called Replikins, whose increase in concentration in virus or other organism proteins (Replikin Count(TM) = number of replikins per 100 amino acids) is associated with rapid replication. ...

NeurogesX Provides U.S. Regulatory Update for Qutenza(TM)

... of August 16, 2009. NeurogesX' second most advanced product candidate, NGX-1998, is a topically applied, liquid formulation containing a high concentration of capsaicin designed to treat pain associated with neuropathic pain conditions. NGX-1998 has completed three Phase 1 studies and NeurogesX is ...

NeurogesX to Present at Needham Life Sciences Conference

... of August 16, 2009. NeurogesX' second most advanced product candidate, NGX-1998, is a topically applied, liquid formulation containing a high concentration of capsaicin designed to treat pain associated with neuropathic pain conditions. NGX-1998 has completed three Phase 1 studies and NeurogesX is ...

Genomatica Produces Pure BDO From Natural Sugars

... to show that its organisms can directly produce BDO in a fermentation broth from sugars; next, to show that the yield and rate of BDO production and concentration can reach levels consistent with commercial goals; and finally, to show that BDO can be purified from the fermentation broth using a cost-effective ...

Laboratory Test May Predict Effectiveness of ERBITUX(R) for Individual Colorectal Cancer Patients

... assay was also performed on 54 cultures of primary human colorectal cancer. Cell lines and specimens were treated with a serial dose of 10 concentration of cetuximab for 72 hours, stained with a nuclear dye, and remaining post-treatment live cells were counted. Two of the examined cell lines showed ...

Serial Monitoring With ImmuKnow(R) is Useful in the Risk Assessment of Kidney Transplant Recipients

... immune function that assesses cellular immune status by detecting cell-mediated immunity (CMI) in adult immunosuppressed patients. It measures the concentration of adenosine triphosphate (ATP) released from CD4 cells following cell stimulation. The ImmuKnow test is a qualitative assay and does not directly ...

Plexus Awarded Development Contract With QIAGEN

... risks include customer delays, start-up costs, our potential inability to execute and lack of a track record of order volume and timing; the risks of concentration of work for certain customers; the weakness of the global economy and the continuing instability of the global financial markets and banking system, ...

ZyGEM Corp. Signs Agreement to Incorporate Its Breakthrough DNA Extraction Technology Into Rubicon's Research and Diagnostic Products

... including qPCR, microarrays, and next-generation sequencing. Rubicon kits amplify small clinical samples into large amounts of pure DNA with uniform concentration and molecular weight that increase the sensitivity, specificity, and reproducibility of analysis in research and diagnostic applications, including ...

Prospect Therapeutics, Inc.'s GCS-100 Inhibited Blood Vessel Formation in a Variety of Cancer Models

... Prospect's lead product candidate, GCS-100, is a carbohydrate molecule designed to inhibit the activity of Galectin-3, a protein found in high concentration in a broad range of human cancers and whose over-expression is associated with poor prognosis in cancer patients. About Joseph F. Finn, Jr., ....

Amgen Exercises Option for Exclusive License to Cytokinetics' Cardiac Contractility Program That Includes CK-1827452

... agents, such as beta-adrenergic receptor agonists or inhibitors of phosphodiesterase activity, increase cardiac cell contractility by increasing the concentration of intracellular calcium, which further activates the cardiac sarcomere. This effect on calcium levels, however, also has been linked to potentially ...

MIT reels in RNA surprise with microbial ocean catch

... able to track the dynamics of small RNA expression in situ provides insight into how microbes respond to environmental changes such as nutrient concentration and physical properties like light and pressure," said Shi. "A very interesting question to follow up in the lab is how much fitness advantage a ...

Swine Flu (H1N1) Infectivity to Increase Markedly and Lethality to Remain Low According to Latest Replikin* Peptide Genomic Data

... and predictive tools are based on the company's discovery of a new group of peptides related to rapid replication called Replikins, whose increase in concentration in virus or other organism proteins (Replikin Count™ = number of replikins per 100 amino acids) is associated with rapid replication. # # # ...
Other Contents
(Date:7/31/2014)... bigeye tuna movements in the northwestern Atlantic Ocean led ... Center at the University of Massachusetts Amherst, found among ... range with pronounced north-south movements from Georges Bank to ... off Cape Hatteras southwest of Bermuda for foraging. , ... study one of the most important commercial tuna species ...
(Date:7/31/2014)... New research, supported by the National Science Foundation ... permafrost uniformly accelerates atmospheric warming, indicating instead that ... they emit into the atmosphere. , The ... Nature , focuses on thermokarst lakes, which occur ... fill with melted fresh water, converting what was ...
(Date:7/31/2014)... genes to the earliest common ancestor of butterflies ... an extensive "Tree of Lepidoptera" in the first ... , Among the study,s more surprising findings: Butterflies ... to large ones, which completely changes scientists, understanding ... that some insects once classified as moths are ...
Breaking Biology News(10 mins):Study of bigeye tuna in Northwest Atlantic uses new tracking methods 2Study of bigeye tuna in Northwest Atlantic uses new tracking methods 3Certain Arctic lakes store more greenhouse gases than they release 2UF study advances 'DNA revolution,' tells butterflies' evolutionary history 2UF study advances 'DNA revolution,' tells butterflies' evolutionary history 3
(Date:7/31/2014)... July 31, 2014 Etymotic Research, ... a new sponsorship of the DrumLine Battle® series ... Etymotic’s hearing protection products ETY•Plugs® and Music•PRO® electronic ... the harmful effects of high-level sound. Etymotic will ... at the Drum Corps International Championships on August ...
(Date:7/31/2014)... Most mommy blogs are simple family journals, ... to attract all mothers from all walks of life. ... whether its high fashion or child rearing. When Felicia ... the Internet was so segmented. “I found myself visiting ... and then search Google to get information on another. ...
(Date:7/31/2014)... and saliva tests that help accurately predict recurrences of ... The tests screen for DNA fragments of the human ... mouth or other parts of the body. A description ... issue of JAMA Otolaryngology Head & Neck ... in the year after initial therapy to take an ...
(Date:7/31/2014)... LDM Global ( http://www.ldmglobal.com ) announces the ... simplified and predictable with fixed fees across the board, ... international provider of legal discovery management services for law ... apparent that both the courts and legal counsel alike ... complex pricing structure that plagues the litigation support industry. ...
(Date:7/31/2014)... By Steven Reinberg ... (HealthDay News) -- Many obese and overweight kids don,t ... weight almost impossible, researchers report. In a new ... weight. Fewer than 3 percent overestimated it. About 25 ... 1 percent overestimated it, according to the study. ...
Breaking Medicine News(10 mins):Health News:Etymotic Research Becomes The Official Hearing Protection Sponsor Of DrumLine Battle 2Health News:Mommylish Launches Its Website 2Health News:Blood and saliva tests help predict return of HPV-linked oral cancers 2Health News:LDM Global Announces Predictable Simple Fixed-Fee Pricing 2Health News:1 in 4 U.S. Kids Underestimate Their Weight, Study Finds 2Health News:1 in 4 U.S. Kids Underestimate Their Weight, Study Finds 3
Other TagsOther Tags