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Calcium in Biological Technology

Keryx Biopharmaceuticals Reports Positive Phase 2 Study Results of Zerenex (Ferric Citrate) for the Treatment of Hyperphosphatemia in End-Stage Renal Disease Patients

... approximately 6 to 15 tablets/capsules per day of calcium acetate, calcium carbonate, lanthanum carbonate or sevelamer ... were taking > 12 tablets/capsules per day of calcium ...

New Discoveries on a Fingertip Test for Screening Silent Heart Disease Promising Results of Recent Clinical Studies to be Presented during the 2009 American College of Cardiology Conference, March 29th - April 1st in Orlando

... 30, 2009, 3:30 PM - 4:30 PM Topic: CT Coronary calcium and Noncoronary CT Applications Presentation ... the chance of having a coronary blockage or calcium score >100 -both of which would place these ... blood pressure. Furthermore, unlike coronary calcium or carotid IMT, it is a dynamic marker and ...

Frost & Sullivan Recognizes ApaTech's Leadership in Orthopedic Biologics

... called Actifuse, which is based on silicated calcium phosphate. This development is a definitive ... the risks involved with surgery. In particular calcium phosphates have emerged as the alternative of ... to selectively replace phosphate groups in the calcium phosphate crystal lattice. This new material ...

RoundTable Healthcare Partners Facilitates Product Acquisition for CorePharma

... Leucovorin calcium Augments CorePharma's Growing Product Portfolio ... the acquisition of an ANDA for Leucovorin calcium tablets. Leucovorin calcium tablets are the generic equivalent to the ...

AIM Pharmakon (API) Announced a New Proprietary Premium-Quality Natural Concentrated Liquid Calcium and Mineral Supplement Now Available Direct to Consumers

... AimCa++DONAN (TM), a new premium-quality liquid calcium mineral concentrate for bone development and ... flavors. Adequate intake of bioavailable calcium helps to achieve peak bone mass, strong teeth, ... phases, baby-boomers and seniors needing extra calcium supplementation. "The role ...

Sea urchin yields a key secret of biomineralization

... hidden mechanism to transform amorphous calcium carbonate into calcite, the stuff of seashells. ... describes how the lowly sea urchin transforms calcium carbonate the same material that forms "lime" ... and the first one in which the amorphous calcium carbonate precursor was discovered in 1997 by the ...

Leading Heart Specialist Joins Duska Therapeutics as Scientific Consultant

... heart function is by activating the main calcium channel in the heart to release calcium from intracellular stores. calcium is the primary determinant of contractility in ... main ion channel in the heart that supplies the calcium necessary for the heart to contract. CDP-1050 is ...

Jellyfish Protein Shows Potential to Help With Memory

... from the study due to side effects. "Too much calcium within a brain cell impairs its function and ... fewer calcium-binding proteins. This causes calcium levels to rise throughout the nervous system. Neurons are flooded with dangerous levels of calcium and our brains slow down. We are excited to see ...

Cytochroma and Mitsubishi Tanabe form partnership for chronic kidney disease therapies in U.S. and Asia

... of administration. Excessive levels of iPTH cause calcium to be released from bone and into the blood, ... maintain a state of balance (homeostasis) between calcium and phosphate in the body. The low levels of ... vitamin D hormone and lack of homeostasis between calcium and phosphate is detected by the ...

BioTrends Releases Quarterly TreatmentTrends(TM): Nephrology Report Highlighting Market Trends for Renal Anemia, Hyperphosphatemia, and Secondary Hyperparathyroidism

... and is of significantly less concern than calcium absorption. Both Fresenius Medical Care's PhosLo and calcium carbonate continue to be impacted by concerns with calcium, although calcium binders are expected to remain the preferred ...

Radiesse(R) Dermal Filler Featured Prominently in Journal of Dermatologic Surgery Special Issue on Fillers

... were: -- A 52-Month Summary of Results Using calcium Hydroxylapatite for Facial Soft Tissue ... CARRUTHERS, MD, AND BRUCE B. FORSTER, MD -- calcium Hydroxylapatite Filler for Facial Rejuvenation: A ... MD -- Neocollagenesis after Injection of calcium Hydroxylapatite Composition in a Canine Model - ...

New Study by BioTrends Highlights Practice Management Shifts Among European Nephrologists

... three months, primarily in the dialysis setting. calcium based binders are still the predominant binders ... exceeds 53%. Non-calcium based binders outperform calcium based agents on most product attributes, and ... an advantage over Fosrenol in three out of four. calcium carbonate, the leading calcium preparation, tends ...

Independent Study Confirms Superior Properties of ZPC(TM) Enhanced Calcium Composite Bone Grafts

... resorption of Fortoss Vital. Fortoss Vital is a unique, bi-phasic calcium composite bone graft material having a negative surface charge which ... Reference: Smeets et al. " A new biphasic osteoinductive calcium composite material with a negative Zeta potential for bone augmentation." ...

deCODE Discovers a Gene Linked to Risk of Kidney Stones and Osteoporosis

... that regulate the passage of ions and small solutes between cells. As calcium is a key component both of most kidney stones and of bone, the deCODE team ... calcium. The results suggest that the SNP may be contributing to increased calcium excretion in urine, a major risk factor for kidney stones and also a sign ...

Amgen Exercises Option for Exclusive License to Cytokinetics' Cardiac Contractility Program That Includes CK-1827452

... calcium, which further activates the cardiac sarcomere. This effect on calcium levels, however, also has been linked to potentially life-threatening side ... have been shown to work in the absence of changes in intracellular calcium by a novel mechanism that directly stimulates the activity of the cardiac ...

ETEX Corporation Announces FDA Clearance of Small Size Beta-bsm(TM) Injectable Paste and Gamma-bsm(TM) Moldable Putty

... are bone substitute materials based on ETEX's proprietary nanocrystalline calcium phosphate technology. (Logo: ... in 1989, ETEX Corporation develops, manufactures and commercializes calcium phosphate-based biomaterials for improved orthopedic clinical outcomes. A ...

The Journal of Cardiac Failure Publishes Results From Celladon Corporation's First-in-Human Phase 1/2 Clinical Trial in Advanced Heart Failure

... calcium Upregulation by Percutaneous Administration of Gene Therapy in Cardiac ... key enzyme deficiency in advanced heart failure, SERCA2a, which regulates calcium cycling and contractility in heart muscle cells. Celladon's first product ...

ChanTest Acquires Applied Cell Sciences

... reaction is mediated by cardiac GPCR beta-receptors activating cardiac calcium channels, thereby increasing cardiac pumping. Drugs may affect function of the heart via beta-receptors, calcium channels, or both. We at ACS are honored to become a part of ChanTest - ...

Innovative Biosensors and ProGenTech Partner to Develop a Rapid Diagnostics System

... biosensors expressing membrane bound, pathogen specific antibodies and a calcium sensitive bioluminescent molecule. Cross-linking of the antibodies by ... amounts of the specific pathogen leads to elevation of intracellular calcium and light emission. The amplified light output can then be detected using ...

BioTrends Releases TreatmentTrends(TM): US Nephrology, an Ongoing Syndicated Publication Providing Insight into Physician Perceptions and Management of Renal Anemia, Hyperphosphatemia, and Secondary Hyperparathyroidism

... market dynamics will likely come from the recent introduction of generic calcium acetate from Roxane Laboratories, as very few Nephrologists oppose the ... in Shire's Fosrenol, while continued shifts are expected away from calcium based binders. The proposed bundling structure is also expected to ...

European Nephrologists Share Insights on the Management of Renal Anemia and Hyperphosphatemia in Latest BioTrends Report

... of their dialysis patients are above the target level for phosphorus. calcium based phosphate binders are the most frequently prescribed binders in both ... is a high prevalence of combination binder therapy typically involving a calcium based agent combined with Genzyme's Renagel. Future share projections ...

Video: 8-Minute Film Documentary Explores Why Humans Age

... years, losses of iron and copper during menstruation, and donation of calcium to offspring, explains why women avoid the " rusting and calcification " ... why males at age 40 have double the amount of iron and four times as much calcium in their bodies compared to an equally aged female, and experience double ...

China Sky One Medical, Inc. Obtains Production Rights for Nine New Drugs

... been approved by the SFDA for production and sale. -- Oyster Shell calcium Granules and Oyster Shell calcium Tablets: for the treatment of calcifames and osteoporosis, especially ...

Genzyme Launches Renvela(R) in the U.S. for Dialysis Patients

... is the only phosphate binder available that does not contain either calcium or a metal. It has an established safety profile, is not systemically absorbed and provides phosphorus control without the concerns of calcium or metal accumulation. The National Kidney Foundation's 2003 Kidney ...

ETEX and LifeNet Health, Inc. Enter Agreement

... of DBM with the fast setting and osteoconductive properties of synthetic calcium phosphate. Unlike other DBM products on the market, EquivaBone(TM) flows ... in 1989, ETEX Corporation develops, manufactures and commercializes calcium phosphate-based biomaterials for improved orthopedic clinical outcomes. A ...

NPS Pharmaceuticals Announces Approval of Cinacalcet HCl in Japan

... secondary hyperparathyroidism, are associated with altered metabolism of calcium and phosphorus, bone pain, fractures, and an increased risk for ... a treatment for this condition and for the treatment of elevated levels of calcium in patients with parathyroid carcinoma. NPS president and CEO Dr. Tony ...

FDA Approves Genzyme's Renvela(TM) for Dialysis Patients

... is the only phosphate binder available that does not contain either calcium or a metal. It has an established safety profile, is not systemically absorbed and provides phosphorus control without the concerns of calcium or metal accumulation. The National Kidney Foundation's 2003 Kidney ...

DAIICHI SANKYO EUROPE is Applying for Approval of its New Combination Product of Olmesartan and Amlodipin

... two substances, the angiotensin receptor blocker (ARB) Olmesartan and the calcium antagonist Amlodipin. When approved, the new combination for treatment of ... sales growth in Europe(1). Amlodipin is one of the most frequently used calcium antagonists in many European countries. "Hypertension is currently viewed ...

PREOS(R) Granted U.S. Orphan Drug Status for Treatment of Hypoparathyroidism

... treatments include vitamin D analogs and large doses of supplemental calcium to relieve the symptoms of neuromuscular irritability associated with ... hypercalciuria and nephrocalcinosis, a serious condition characterized by calcium deposition in the kidneys. PREOS could potentially be a first-in-class ...

FDA Accepts ISO-Vorin(TM) New Drug Application Amendment Submitted by Spectrum Pharmaceuticals

... the ISO-Vorin(TM) application. ISO-Vorin(TM) is the pure active isomer of calcium leucovorin. calcium leucovorin is used after the administration of high-dose methotrexate in ...

Reclast(R) Receives US FDA Approval as First and Only Once-Yearly Treatment for Women With Postmenopausal Osteoporosis

... with Zometa. All patients with Paget's disease should receive 1500 mg of calcium in divided doses and 800 IU of vitamin D daily, particularly in the two ... It is recommended that patients with postmenopausal osteoporosis take calcium and vitamin D supplements, if dietary intake is not sufficient. For more ...

Solon Manufacturing Company Acquires PurFybr Brands; Adds Influenza Virus Diagnostic Swabs to Product Line

... flu) virus. PurFybr, which operates manufacturing facilities in Munster, Ind., was one of the first companies to spin polyester, rayon, and calcium alginate onto thin wires. Its products are designed to minimize the risk of irritation and contamination during the collection of specimens for a ...

China Sky One Medical, Inc. Announces Record Fourth Quarter and Fiscal Year 2008 Results

... is now available in 26 countries and regions. In March, the Company announced that it received SFDA approval to manufacture two new drugs, calcium Folinate injection, intended as an auxiliary therapy for sprue, (a disease of the small intestine), infancy- related megaloblastic anemia, and ...

First high-resolution images of bone, tooth and shell formation

... Friday 13 March edition. Led by dr. Nico Sommerdijk, the researchers imaged small clusters with a cross-section of 0.7 nanometer in a solution of calcium carbonate (the basic material of which shells are made). They showed for the first time that these clusters, each consisting of only about ten ions, ...

Mental Stimulus Package: Government Officials who Forgot to Pay Taxes Will Receive Free Memory-boosting Supplement

... focused on the discovery, development and commercialization of new compounds to fight the aging process. The company's products focus on restoring calcium balance related to neurodegenerative disorders and other destructive age-related mechanisms. Quincy Bioscience is developing health applications of ...

Cordex Pharma Forms Heart Failure Medical Advisory Board

... nitric oxide to physiologic levels. The primary therapeutic target is the ryanodine receptor, the main ion channel in the heart that supplies the calcium necessary for the heart to contract. CDP-1050 is expected to enter a Phase 2 clinical trial this year. About Cordex Pharma, Inc. Cordex is ...

Traditional Risk Factors Often Miss Heart Disease Warning Signs

... nearly half (49 percent) of patients. In addition, 38 percent of the participants had coronary atherosclerosis as reflected in EBCT derived coronary calcium scores, and 24 percent of the participants had "at-risk" levels of C-reactive protein (above 3 mg/dl). All patients were screened for emerging ...

Martek Announces Fourth Quarter and FY 2008 Financial Results

... DHA, Canola Oil & Extra Virgin Olive Oil with life'sDHA(TM); Life Balance(TM) Tortillas Fortified with Vitamins and calcium with life'sDHA(TM); Omega To-Go beverage with life'sDHA(TM); Glenny's Marshmallow Treats with life'sDHA(TM) and 8th Continent ...

Duska Therapeutics Provides Program Update and Reports Third Quarter 2008 Financial Results

... levels of NO. The principal therapeutic target is the ryanodine receptor, the main ion channel in the heart that supplies the calcium necessary for the heart to contract. CDP-1050 is expected to enter a Phase 2 clinical trial early next year. -- Acquisition of ...

Genmab A/S: Ofatumumab Pivotal CLL Data to be Presented at ASH

... Poster I-682 - Complement (C) Activation Followed by Penetration of the Membrane Attack Complex (MAC) on B Cells Opsonized with CD20 Mabs Allows for calcium Influx Which Induces Streamers. Poster I-683 - Binding of Submaximal C1q to B Cells Opsonized with Anti-CD20 Mabs Ofatumumab (OFA) or Rituximab ...
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