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Acids in Biological Technology

Fitting pieces for biosensors

... meaning piece). Aptamers consist of nucleic acids and have a three-dimensional structure that ... a huge pool of 10 million x 100 million nucleic acids with different sequences. This selection method ... a fluorescence molecule is added to the nucleic acids during the SELEX procedure to make them visible. ...

Pressure BioSciences, Inc. and the J. Craig Venter Institute Announce Collaboration Agreement & Purchase of a PCT System

... is an exciting tool for extracting nucleic acids and proteins from challenging biological samples ... to improve the extraction of proteins and nucleic acids from biological samples, a key step in laboratory ... a simple solution for the extraction of nucleic acids and proteins from challenging biological samples; ...

Human clinical study demonstrates superior Neptune Krill Oil NKO(R) pharmacokinetic profile

... by measuring the levels of the omega-3 fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic ... long-term bioavailability of the omega-3 fatty acids EPA and DHA of each of the formulations ... mg NKO(R). Concentrations of the omega- 3 fatty acids EPA and DHA were analyzed in plasma and ...

High-quality DNA/RNA from Microorganisms in Environmental Samples

... primarily on advancing powerful tools for nucleic acids and protein purification, today announced the launch of two new kits for the isolation of nucleic acids from environmental samples, the Soil DNA ... high levels of PCR inhibiton in nucleic acids isolated from environmental samples. I am very ...

Sigma-Aldrich and the University of Illinois Offer New Boronic Acid Surrogates to Researchers Worldwide Through Licensing Agreement

... acid, "MIDA") that reversibly modulates boronic acids toward cross-coupling. The MIDA-ligated boronic ... iterative cross-coupling, MIDA-protected boronic acids (i.e., MIDA boronate esters) have substantially enhanced shelf lives relative to the free boronic acids that often suffer from limited bench top ...

Citrate appears to control buckyball clumping but environmental concerns remain

... 60 , he said. We think citrate and other organic acids with a carboxyl group make C 60 more water ... will present Effects of small molecular weight acids on C 60 aggregate formation and transport (ENVR ... know how they will react. There are many organic acids in the environment. He concludes, There are ...

Nastech Assigns Intellectual Property Related to the Development of RNA-Based Therapeutics to its Subsidiary, MDRNA, Inc.

... Compositions and Methods for Complexes of Nucleic acids and Organic Cations -- Cationic Peptides ... Compositions and Methods for Complexes of Nucleic acids and Peptides -- Phage Displayed Cell Binding ... -- Nanoparticles for Delivery of Nucleic acids and Stable Double-Stranded RNA -- Method ...

Amarin Announces Initiation of Cardiovascular Development Strategy

... Known Therapeutic Benefits of Unsaturated Fatty acids in Cardiovascular ... known therapeutic benefits of unsaturated fatty acids in cardiovascular disease. Amarin plans to ... known therapeutic benefits of unsaturated fatty acids in cardiovascular disease. Amarin also has a ...

Amarin Announces Publication of Pre-Clinical Memory Data in Journal of Neurochemistry

... Prostaglandins Leukot Essent Fatty acids 70, 391-7. 2) Martin D. S., Spencer P., Horrobin ... is reversed. Prostaglandins Leukot Essent Fatty acids 67, 121-30. 3) McGahon B. M., Martin D. S., ... D. F. (2003) Effects of dietary n-3 or n-6 fatty acids on interleukin-1beta-induced anxiety, stress, and ...

New method may accelerate drug discovery for difficult diseases like Parkinson's

... found that both effective cyclic peptides needed only the first four amino acids to work and those amino acids had a common motif (cysteine any amino acid a hydrophobic amino acid ...

Norgen Biotek Corp. Announces OEM Manufacturing & Supply Agreement with Exiqon A/S

... company focusing primarily on advancing powerful tools for nucleic acids and protein purification, today announced the signing of an OEM agreement ... were not disclosed. "Norgen is an experienced provider of nucleic acids purification kits and we look forward to working with them to provide the ...

New Insights into the Mechanism of Action of Antipsychotic Drugs

... effect of antipsychotics on the biosynthesis and regulation of fatty acids and cholesterol supports a key role of lipid homeostasis in schizophrenia" ... effect of antipsychotics on the biosynthesis and regulation of fatty acids and cholesterol supports a key role of lipid homeostasis in ...

CV Therapeutics Initiates Phase 1 Clinical Trial of CVT-3619, a Novel Potential Treatment for Cardiometabolic Diseases

... breakdown in fats, also known as lipolysis, and a lowering of free fatty acids in preclinical models. Preclinical studies also have shown that CVT-3619 ... a first-in-class agent that appears to inhibit the release of free fatty acids from fat cells and has the potential to meet a tremendous unmet need by ...

Pressure BioSciences, Inc. Releases Novel, PCT-dependent Sample Preparation Kit for Systems Biology Studies

... for the simultaneous extraction, isolation, and fractionation of nucleic acids (DNA and RNA), proteins, and lipids from animal and plant samples ... methods available today extract lipids in addition to proteins and nucleic acids from the same biological sample -- lipid extraction is very important, and ...

Pressure BioSciences, Inc. Announces the Market Release of its PCT-Enhanced Trypsin Digestion Application for Proteomics

... information about proteins, their peptide building blocks, the amino acids that make up the peptides, and the nucleic acids (DNA and RNA) that instruct the cell to produce the proteins. Dr. ...

Molecular changes in brain fluid give insight into brain-damaging disease

... The level of a number of metabolites, including some known as fatty acids and phospholipids, was observed to increase during infection. Consistent with this, a protein known to be important in the generation of fatty acids was found to be increased in the brain of monkeys with SIV-induced ...

The Omega-3 Industry Leader, Croda Health Care, selects Neptune Technologies' Ingredients for New Essentially Brand

... enhanced to target maximum consumer health performance. The omega-3 fatty acids EPA (eicosapentaenoic acid) and DHA (docosahexaenoic acid) are ... by International Society for the Study of Fatty acids and Lipids for optimum foetal development. ...

GenVault and the National Center for Forensic Science to Present Novel Technology for Room Temperature Storage of RNA

... stabilizing solute which creates a matrix that can safely maintain nucleic acids such as DNA and RNA in the dry-state at room temperature. Because the matrix is reversible, nucleic acids can be retrieved with minimal effort, further the matrix is capable of ...

Scientists discover how cancer may take hold

... or FRET, to monitor the levels of, tryptophan, one of the essential amino acids human cells need for viability, explained lead author Thijs Kaper. Humans ... body. The FRET system detects metabolites such as sugars and amino acids using a biosensor tag. A protein is genetically fused to tags at opposite ...

EGEN, Inc. Announces the Promotion of Jason Fewell, Ph.D., to Vice-President of Preclinical Research and Development

... (DNA and RNAi) delivery. The Company has a significant intellectual property position in delivery systems, their novel compositions with nucleic acids and their therapeutic applications. EGEN's research pipeline includes products involving siRNA, shRNA and plasmid DNA for the treatment of various ...

Synthetech Reports First Quarter Fiscal 2010 Results

... synthesis firms, emerging biotechnology (virtual pharmaceutical) and medical device companies. We also supply catalog quantities of specialty amino acids to research institutions, universities and drug discovery firms. Forward-Looking Statements This press release contains "forward ...

SEQUENOM Reports Second Quarter 2009 Financial Results and Highlights

... the versatility of the MassARRAY system with the company's SEQureDx technology, which enables the detection of circulating cell-free fetal nucleic acids in a maternal blood sample. The company is also developing tests for oncology, infectious diseases and other disorders. The company was founded in ...

SEQUENOM Announces Launch of MassARRAY Compact 96 System

... versatility of the MassARRAY system with the company's SEQureDx(TM) technology, which enables the detection of circulating cell-free fetal nucleic acids in a maternal blood sample. The company is also developing tests for oncology, infectious diseases and other disorders. The company was founded in ...

Growing Awareness and Increased Investments Lead to Growth of Biotechnology Applications in the Food & Beverage and Dietary Supplements Sector, Reveals Frost & Sullivan

... resulting in innovative food and beverage products with improved functional and health benefits. Production of polyunsaturated fatty acids (PUFA), probiotics, and enzymes are some of the key commercialized biotechnology applications in India. In India, consumer awareness about these new ...

DNA Software, Inc. Awarded $2.5 M in NIH Funding to Develop Pioneering Nucleic Acid-based Technologies

... Modeling Platform™), the core engine that runs all of DNA Software's tools, models in silico the folding and hybridization of nucleic acids with exception accuracy. Visual OMP™ is a platform program for the design, simulation, and analysis of probes/primers, RT-PCR, qPCR, Multiplex ...

Cadila Pharmaceuticals Launches Joint Venture With Novavax in India

... required for viral replication. Once injected into the body, VLPs trigger an immune response to the virus. Because VLPs do not contain viral nucleic acids (DNA or RNA), they cannot replicate, and therefore, they present no threat of infection to a person being vaccinated. The VLP is believed to be ...

DOR BioPharma Announces Issuance of European Patent for its LPM(TM) Oral Drug Delivery Technology

... tract. Other sensitive drugs that can be delivered orally with the LPM(TM) system include various classes of drugs such as peptides, nucleic acids and proteins which are degraded in the stomach and small intestine. Corresponding patents in the United States and elsewhere are currently pending. ...

New Report Just Published: World Prostate Cancer Therapeutics Market Report

... Prostate Cancer II-61 Positive Results from Use of IMRT in Localized Prostate Cancer II-61 Balanced Intake of Omega-6 and Omega-3 Fatty acids Found to Reduce Prostate Cancer Growth II-62 Sanofi's Taxotere Gains Approval from Nice of UK for Use in Late-Stage Prostate Cancer ...

Celtic Pharma Holdings Announces Investment in Novacta Biosystems Limited

... are a naturally occurring class of antibiotic peptide compounds found in a large number of bacteria. They take their name from the lanthionine amino acids found within their structure ( lanthionine-containing antibiotics). Lantibiotics have demonstrated potential to treat infections caused by agents ...

UCF team's advanced nerve cell system could help cure diabetic neuropathy, related diseases

... So, one line of experiments will be to treat cultured motoneuron systems with factors found in high concentrations in diabetics, such as fatty acids or cholesterol. This will allow them to identify what causes myelin to degrade, which could in turn help them identify targets for new drug therapies ...

Exosome Diagnostics and DxS Diagnostic Innovations Collaborate to Develop Blood-Based Tests for Key Cancer Mutations

... leading Scorpions(R) real-time PCR Mutation Test Kits in conjunction with ExosomeDX's x OS(TM) technology which harvests high-quality nucleic acids from blood exosomes. The collaboration will initially focus on developing blood-based measurement of KRAS, BRAF, EGFR and other key mutations ...

A breakthrough toward industrial production of fluorescent nanodiamonds

... issue. Fluorescence is a major tool in life and material sciences. In biology/medicine, the coupling of fluorescent dyes, to proteins or nucleic acids (RNA, DNA) allows one to investigate their fate and interactions in cultured cells or in the body. Similarly, fluorescence is used in material ...

EGEN, Inc. Announces the Promotion of Khursheed Anwer, Ph.D., to President and Chief Scientific Officer

... (DNA and RNAi) delivery. The Company has a significant intellectual property position in delivery systems, their novel compositions with nucleic acids and their therapeutic applications. EGEN's research pipeline includes products involving siRNA, shRNA and plasmid DNA for the treatment of various ...

Genedata Launches Expressionist with Expanded Mass Spectrometry Biomarker Discovery Capabilities

... said Dr. Othmar Pfannes, CEO of Genedata. Expressionist features support for labelled workflows using Stable Isotope Labeling with Amino acids in Cell Culture (SILAC) and Multiple Reaction Monitoring (MRM) targeted analysis. Usability improvements include blank chromatogram subtraction and ...

Morphotek(R), Inc and Lonza Group Ltd Enter Into Manufacturing Services Agreement

... key growth drivers of the pharmaceutical and biotechnology industries. Lonza has strong capabilities in large and small molecules, peptides, amino acids and niche bioproducts which play an important role in the development of novel medicines and healthcare products. Lonza is a leader in cell-based ...

Vanda Pharmaceuticals to Present Data on Fanapt(TM) and Tasimelteon at the 162nd American Psychiatric Association Annual Meeting

... for the treatment of patients with schizophrenia. NR7-009 Common effect of antipsychotics on biosynthesis and regulation of fatty acids and cholesterol supports a role of lipid homeostasis in schizophrenia. NR1-092 Selective estrogen receptor modulators share the ...

DNA Software, Inc. Honored as One of the 2009 "Michigan 50 Companies to Watch"

... Modeling Platform™), the core engine that runs all of DNA Software's tools, models in silico the folding and hybridization of nucleic acids with exception accuracy. Visual OMP™ is a platform program for the design, simulation, and analysis of probes/primers, RT-PCR, qPCR, Multiplex ...

ImClone Systems and Lonza Walkersville to Discuss Paperless QC Micro at PDA Annual Meeting

... pharmaceutical ingredients both chemically as well as biotechnologically. Lonza has strong capabilities in large and small molecules, peptides, amino acids and niche bioproducts which play an important role in the development of novel medicines and healthcare products. Lonza is a leader in cell-based ...

SeqWright to Invest in LaserGen's Novel Lightning Terminators(TM)

... the savings in both, time and cost, which we expect their technologies to generate." About LaserGen LaserGen, Inc. is an early-stage nucleic acids chemistry company, founded in 2002. The company has been funded through NIH-sponsored small business and research grants to develop a variety of ...

BASF Set To Commercialize pro-t-action(TM) Eliminating Caries Causing Bacteria From the Mouth

... causing bacteria in the oral cavity, like Streptococcus mutans, initiate the onset of tooth decay converting the sugar from food into acids. These acids ultimately destroy tooth enamel, reducing essential minerals protecting the teeth and thus leading to lesions or cavities. Shown in testing, the ...
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