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Mut S is a member of a class of proteins who function to ensure the integrity of the DNA sequence. Mut S plays an integral role in proofreading the nascent strands in DNA replication, in transcription-coupled nucleotide excision repair and in preventing chromosomal recombination between dif......f presenilin, nicastrin, Aph-1 and Pen-2; all four proteins are necessary for full proteolytic activity. The g...atalyzes cleavage of a number of integral membrane proteins including Amyloid precursor protein, Notch, Erb4 and E-cadherin. While Aph-1 stabilizes the presenil...
EBY100 S. cerevisiae Strain from Invitrogen
...fically designed to target and display recombinant proteins on the surface of Saccharomyces cerevisiae. Displayed proteins can be analyzed for their ability to interact with known or putative ligands. pYD1 uses the a-agglut...S-Protein Agarose from Novagen
... medium scale affinity purification of STag fusion proteins produced from appropriate vectors. Sufficient reag...ically retains STag fusion proteins. After unbound proteins are washed away, the target protein is released by incubation of the agarose beads with site-specifi...S-Protein Agarose from Novagen
... medium scale affinity purification of STag fusion proteins produced from appropriate vectors. Sufficient reag...ically retains STag fusion proteins. After unbound proteins are washed away, the target protein is released by incubation of the agarose beads with site-specifi...S. pombe Whole Genome ChIP-on-chip from Agilent Technologies
... location analysis of yeast (S. pombe) DNA binding proteins by pairing chromatin immunoprecipitation (ChIP) with Agilent DNA microarrays. This set delivers robust hybridization and reliable binding data with greater true binding events and fewer false positives. In addition, Agilent provides flexibility by of...S. cerevisiae yeast Whole Genome from Agilent Technologies
...tion analysis of yeast (S. cerevisiae) DNA binding proteins by pairing chromatin immunoprecipitation (ChIP) with Agilent DNA microarrays. This set delivers robust hybridization and reliable binding data with greater true binding events and fewer false positives. In addition, Agilent provides flexibility by of...S. cerevisiae yeast Whole Genome from Agilent Technologies
...tion analysis of yeast (S. cerevisiae) DNA binding proteins by pairing chromatin immunoprecipitation (ChIP) with Agilent DNA microarrays. This set delivers robust hybridization and reliable binding data with greater true binding events and fewer false positives. In addition, Agilent provides flexibility by of...ProteomeLab PA 800 Protein Characterization System from Beckman Coulter
...proteome manipulating and resolving low levels of proteins that range from acidic to basic to membrane-bound....ProteomeLab PF 2D Protein Fractionation System from Beckman Coulter
... The system effectively resolves the thousands of proteins present in cell lysates, addressing a key challeng...he first dimension, chromatofocusing separates the proteins according to their pI, providing information that can be related to traditional isoelectric focusing...Anti-JIP 1 / 2 (SH3) Polyclonal Antibody, Unconjugated, Clone ZMD.177 from Invitrogen
...emonstrated selectivity in its binding to specific proteins of the JNK pathway. In addition to JNK, JIP1 binds to the JNK activator MKK7 (MAP kinase kinase 7) and the MKK7 activators MLK3 (mixed-lineage protein kinase 3) and DLK (dual leucine zipper-bearing kinase), all at separate binding sites. JIP1s assemb...Custom Arraying Service from Whatman, Inc
...s instrumentation to have FAST Slides printed with proteins from S&Ss antibody menu or from their own library. Processing of the arrays is performed by the customer. Its as easy as 1-2-3 Contact S&S to discuss your needs with an expert and define the best adapted configuration to your specific arrays. Selec...pET GST Fusion System 42 plus Competent Cells from Novagen
... commonly used as a fusion partner when expressing proteins in E. coli (1). The GSTTag sequence has been repor... in a soluble, properly folded form, GSTTag fusion proteins can be purified with immobilized glutathione. Gentle elution is achieved with buffers containing red...pET GST Fusion System 42 from Novagen
... commonly used as a fusion partner when expressing proteins in E. coli (1). The GSTTag sequence has been repor... in a soluble, properly folded form, GSTTag fusion proteins can be purified with immobilized glutathione. Gentle elution is achieved with buffers containing red...pET GST Fusion System 41 plus Competent Cells from Novagen
... commonly used as a fusion partner when expressing proteins in E. coli (1). The GSTTag sequence has been repor... in a soluble, properly folded form, GSTTag fusion proteins can be purified with immobilized glutathione. Gentle elution is achieved with buffers containing red...pET GST Fusion System 41 from Novagen
... commonly used as a fusion partner when expressing proteins in E. coli (1). The GSTTag sequence has been repor... in a soluble, properly folded form, GSTTag fusion proteins can be purified with immobilized glutathione. Gentle elution is achieved with buffers containing red...Qproteome Nuclear Subfractionation Kit from QIAGEN
...paration and fractionation of nucleic-acid binding proteins Efficient separation of nuclei from cytosolic proteins A huge reduction in sample complexity, greatly facilitating study of low-abundance nuclear proteins ...ProteoSpin Micro CBED Kit from Norgen Biotek Corporation
...d protocols are provided for both acidic and basic proteins with no need for formulation. No molecular weight cutoff - Based on an ion exchange mechanism, a broad size range of proteins, from peptides to antibodies can be processed. Proteins bind while salts are discarded in flowthrough - SiC has an inherent ...SOS Soluble Protien Service from Genlantis
...or significantly enhance solubility of recombinant proteins expressed in BL21(DE3) cells. The SOS process uses 24 unique conditions per gene in order to find the optimal chemical environment for maximizing soluble protein expression. The SOS program is designed to allow investigators to avoid and/or alleviate...EvoQuest ™ Custom Laboratory Services from Invitrogen
...ur projects are focused on sequencing, analysis of proteins expressed by specific genes, or in other areas of genomics and proteomics, EvoQuest ™ Custom Laboratory Services can help you meet your research and manufacturing challenges. Invitrogen scientists provide the expertise required to take your pro...Ph.D. Peptide Display Cloning System from New England Biolabs
...phage superinfection are required. Since displayed proteins longer than 20-30 amino acids have a deleterious effect on the infectivity function of pIII in phage vectors, this vector is suitable only for the display of short peptides. Included with the cloning vector is an insert extension primer as well as a ...Free Activin A ELISA Kit from Diagnostic Systems Laboratories, Inc.
...es (2). In addition to their endocrine role, these proteins have been shown to affect the growth and different...genitor and erythroleukemia cells (2). Two binding proteins have been described for the Activins and Inhibins: Follistatin and a-2 macroglobulin. Activins are b...Free Activin AB ELISA Kit from Diagnostic Systems Laboratories, Inc.
...es (2). In addition to their endocrine role, these proteins have been shown to affect the growth and different...genitor and erythroleukemia cells (2). Two binding proteins have been described for the Activins and Inhibins: Follistatin and a-2 macroglobulin. Activins are b...Free Activin B ELISA Kit from Diagnostic Systems Laboratories, Inc.
...es (2). In addition to their endocrine role, these proteins have been shown to affect the growth and different...genitor and erythroleukemia cells (2). Two binding proteins have been described for the Activins and Inhibins: Follistatin and a-2 macroglobulin. Activins are b...Modern Protein Chemistry: Practical Aspects from Pierce Biotechnology, Inc.
...ion and Cross-linking include: Reactive groups of proteins Choice and design of cross-linking reagents Homo...alysis and complications Cross-linking to soluble proteins Cross-linking of membrane proteins Preparation of enzyme conjugates Preparation of immunotoxins a...Protein-Protein Interactions, from Pierce Biotechnology, Inc.
...f protein interactions as an essential aspect of a proteins function in the biological system. As a result, in... for the discovery and or confirmation of a target proteins interaction....Mouse Anti-GST Tag Monoclonal Antibody, Unconjugated from Novagen
...purified antibody is suitable for detecting fusion proteins containing the GSTTag sequence expressed in E. col...fluorescence or immunoprecipitation. GSTTag fusion proteins can be efficiently expressed using Novagens pET-41 or pET-42 vector series....MagneGST™ Protein Purification System from Promega
...magnetic stand) or automated procedure. GST-tagged proteins can be purified on a small scale from 1ml of cultu...n purification of glutathione-S-transferase fusion proteins from cleared or crude E. coli cell lysate....ProXPRESS 2D Proteomic Imaging System, Professional Package from PerkinElmer
...ucible detection and quantitation of low abundance proteins on large 2D gels. The systems laser-like high resolution provides a statistically significant number of data points per protein spot. This means more accurate and reliable biological information measurements, which translates into fewer failed experi...ProXPRESS™ 2D Multi-User Applications Package from PerkinElmer
...ucible detection and quantitation of low abundance proteins on large 2D gels. The systems laser-like high resolution provides a statistically significant number of data points per protein spot. This means more accurate and reliable biological information measurements, which translates into fewer failed experi...Mega Western Protein Array from BioChain
...d ready to use, so that you can immediately screen proteins of interest without the hassle of obtaining hard to find tissues and processing the proteins yourself....Multiple Affinity Removal System from Agilent Technologies
...identify and characterize high-value, low-abundant proteins faster and more efficiently without interferences....ows you to remove unwanted, multiple high-abundant proteins from human serum, plasma, CSF samples and more with just one device. With this revolutionary system...ProXPRESS™ 2D Proteomic Imaging System, Basic Package from PerkinElmer
...ucible detection and quantitation of low abundance proteins on large 2D gels. The systems laser-like high resolution provides a statistically significant number of data points per protein spot. This means more accurate and reliable biological information measurements, which translates into fewer failed experi...SOS Soluble Protien Service from Genlantis
...or significantly enhance solubility of recombinant proteins expressed in BL21(DE3) cells. The SOS process uses 24 unique conditions per gene in order to find the optimal chemical environment for maximizing soluble protein expression. The SOS program is designed to allow investigators to avoid and/or alleviate...ChemiLucent Plus Western Blot Enhancing Kit (Trial size) from CHEMICON
...ferent antibodies and antigens, such as structural proteins (Actin), enzymes (GAPDH) or membrane proteins (EGFR).It can significantly boost Western blot signals, and is compatable with other enhancing mecha...Anti-Heat Shock Protein 75 (hsp75) (TRAP-1) Ab-2 Monoclonal Antibody, Unconjugated from Lab Vision
...ul conditions trigger the synthesis of a family of proteins known as heat shock proteins (HSPs), more appropriately called as stress response proteins (SRPs). The Hsp90 family of proteins ...Rabbit Anti-Mint3 Polyclonal Antibody, Unconjugated from ABR-Affinity BioReagents
...ily is a group of evolutionarily conserved adaptor proteins that function in membrane transport and organizati...-terminal half, the carboxy-terminal half of these proteins is highly conserved. Within this conserved portion there exists a phosphotyrosine-binding (PTB) and......is located on chromosome 19 (19q13.1). Fibrillarin proteins have been cloned and sequenced from several other species (Mouse, accession P35550, Xenopus accession P22232, C. elegans accession Q22053, and S. pombe accession P35551). The N terminal 80 amino acids contain multiple copies based on the peptide RGG,......we in-troduced a new concept, namely production of proteins under dual controls: (i) at tran-scriptional level at the T7 phage promoter, and (ii) at the DNA replication level by amplifying the plasmid copy number, The main advantage of our dual-control ex-pression plasmid is that it retains practically all of...pYD1 Yeast Display Vector from Invitrogen
...fically designed to target and display recombinant proteins on the surface of Saccharomyces cerevisiae. Displayed proteins can be analyzed for their ability to interact with known or putative ligands. pYD1 uses the a-agglut......tection Systems allow non-radioactive detection of proteins synthesized in vitro. Using these systems, biotiny...ated lysine residues are incorporated into nascent proteins during translation, eliminating the need for labeling with [35-S]methionine or other radioactive ami...ProteoSpin Urine Protein Concentration Kit from Norgen Biotek Corporation
...cedure for concentrating dilute solutions of urine proteins from small volumes of urine. The kit employs spin-...oprietary protein resin as an ion exchanger. Urine proteins will bind to the column, while non-specifically bound proteins and salts are easily removed from the...UBC Fractions Extract from GeneTex
...f appropriate levels of short-lived and regulatory proteins as important and diverse as those involved in cell...The ubiquitin-proteasome pathway deconstructs most proteins in the eukaryotic cell cytosol and nucleus. Others are degraded via the vacuolar pathway which inclu...26S Proteasome Fraction Extract from GeneTex
...f appropriate levels of short-lived and regulatory proteins as important and diverse as those involved in cell...The ubiquitin-proteasome pathway deconstructs most proteins in the eukaryotic cell cytosol and nucleus. Others are degraded via the vacuolar pathway which inclu...Extracti-Gel D Detergent Removing Gel AffinityPak Columns from Pierce Biotechnology, Inc.
...on of unwanted detergent from solutions containing proteins or other macromolecules Applications: Reducing octyl glucoside concentration to prevent inhibition of the interaction of pure β-adrenergic receptor and pure nucleotide regulatory protein. Removing residual SDS in 6 M urea/0.05 mM Tris acetate, p...ProteoSpin Micro Detergent Clean Up Kit from Norgen Biotek Corporation
...in. Solutions for processing both acidic and basic proteins are included. No detergent carryover - Unlike HPLC procedures, each sample is processed individually using its own spin tube providing no carryover or column bleed from sample to sample. Useable with a variety of detergents - The kit can be used to r...Ubiquitin/Proteasome Fraction II Extract from GeneTex
...f appropriate levels of short-lived and regulatory proteins as important and diverse as those involved in cell...The ubiquitin-proteasome pathway deconstructs most proteins in the eukaryotic cell cytosol and nucleus. Others are degraded via the vacuolar pathway which inclu...E-PAGE Blotting Pads (Reusable) 8.6 cm x 13.5 cm from Molecular Probes (Invitrogen)
...VDF membranes are designed for western transfer of proteins (Figure 1 Table 1). Pre-cut extra-thick absorbent Blotting Paper (2.5 mm thickness) for E-PAGE" Gels are also available to accommodate the E-PAGE blotting set-up using a semi-dry transfer apparatus. A proteins properties affect its ability to bind t...IMPACT-CN System from New England Biolabs
...ng elements (termed inteins) to purify recombinant proteins by a single affinity column (1-4) (Figures 1 and 2). This system distinguishes itself from other protein fusion systems by its ability to separate a recombinant protein from the affinity tag without the use of a protease. The IMPACT-CN Protein Fusio...20S Proteasome Fluorometric (AMC) Assay Kit from CHEMICON
...he selective degradation of short-lived regulatory proteins and the rapid elimination of proteins with abnormal conformation (Hershko & Ciechanover 1998; Hochstrasser 1996). The critical protease in...Mouse Anti-PRMT5 Monoclonal Antibody, Unconjugated, Clone PRMT5-21 from GeneTex
...sential regulatory functions by methylation of key proteins in several fundamental areas. These protein include nuclear proteins (Histone 2A, 3, 4), IL enhancer binding factor, nuclear factors (NF45, 90, ILF3, Nucleolin, STAT1, P...FLAG Immunoprecipitation Kit from Sigma-Aldrich
...y resin allows an efficient binding of FLAG-tagged proteins without the need for preliminary steps and calibrations. The immunoprecipitated FLAG-tagged proteins can be efficiently eluted from the resin with acidic conditions or by competition with FLAG peptide....GrabIt™ Protein G Plus/Protein A Kit from Novagen
...;, S•Tag™, or T7•Tag ® fusion proteins are copurified using affinity resins for the tags, and the complexes are retained on a spin filter. The complexes are eluted with sample buffer in preparation for SDS-polyacrylamide gel electrophoresis. An additional kit based on the more traditional...Cell Invasion Colorimetric Assay Kit from CHEMICON
...atrix, a reconstituted basement membrane matrix of proteins derived from the Engelbreth Holm-Swarm (EHS) mouse tumor. We examined the kits performance using human fibrosarcoma (HT-1080) and non-invasive fibroblasts (NIH3T3)....Human Protein Phosphatase 2A alpha (PP2Aa) from Upstate
...rance: routinely evaluated by dephosphorylation of proteins <br<Source: Purified from human red blood cells....Serum Biomarker Chip from Whatman, Inc
...on chip format allows researchers to pattern serum proteins using two- or one-color fluorescent detection methods. Competitive antibody binding and profiling utilizing the FAST Slide technology, the worlds most accepted surface chemistry for proteomic microarray applications. The chip is scanned with any stan...Ubiquitin Fraction I from ABR-Affinity BioReagents
...f appropriate levels of short-lived and regulatory proteins as important and diverse as those involved in cell...The ubiquitin-proteasome pathway deconstructs most proteins in the eukaryotic cell cytosol and nucleus. Others are degraded via the vacuolar pathway which incl......f appropriate levels of short-lived and regulatory proteins as important and diverse as those involved in cell...The ubiquitin-proteasome pathway deconstructs most proteins in the eukaryotic cell cytosol and nucleus. Others are degraded via the vacuolar pathway which inclu......f appropriate levels of short-lived and regulatory proteins as important and diverse as those involved in cell...The ubiquitin-proteasome pathway deconstructs most proteins in the eukaryotic cell cytosol and nucleus. Others are degraded via the vacuolar pathway which inclu......f appropriate levels of short-lived and regulatory proteins as important and diverse as those involved in cell...The ubiquitin-proteasome pathway deconstructs most proteins in the eukaryotic cell cytosol and nucleus. Others are degraded via the vacuolar pathway which inclu...Other ContentslaboratorylaboratorylaboratorylaboratorylaboratorylaboratorylaboratorylaboratorylaboratoryventilationventilationventilationventilationventilationhighhighhighhighhighhighhighhighhighhighprogramprogramprogramprogramprogramprogramprogramprogramprogramtrainingtrainingtrainingtrainingtrainingtrainingtrainingtrainingscientistscientistscientistscientistscientistscientistwritingwritingwritingwritingwritingwritingOther TagsMiraRaping
(Date:10/12/2008)...a new possible explanation for why people who eat ...nst the spread of cancers. , They have shown tha...uits and vegetables, binds to and is believed to i...ole in all stages of cancer progression. , "Most...sed on population studies," says Professor Vic Mor...
(Date:10/12/2008)...technology journal (October 12th) reveals how sci...(LCN) at UCL are using a novel nanomechanical appr...e of the few antibiotics that can be used to comba...The researchers, led by Dr Rachel McKendry and Pro...robes capable of providing new insight into how an...
(Date:10/10/2008)... stem cells with the capacity to build fat, accord...ournal Cell, a Cell Press publication. Although ...mselves, transplants of the progenitor cells isola... normal fat tissue in animals that are otherwise l...he causes of obesity, a condition characterized by...
(Date:10/10/2008)...hnology have shaped not only how we find or share ... project just funded by the National Institutes of...o the next level. , The University of Michigan w...cular data needed to develop computer programs tha...s. The data will be housed in a Web-based resource...
Breaking Biology News(10 mins):Pectin power 2Nanotechnology boosts war on superbugs 2Fat-regenerating 'stem cells' found in mice 2New data resource to advance computer-aided drug design 2Childrens Hospital of Pittsburgh of UPMC Involved in Projects To Develop Nations First Heart Assist Devices for Young Children 15888 1Childrens Hospital of Pittsburgh of UPMC Involved in Projects To Develop Nations First Heart Assist Devices for Young Children 15888 2Childrens Hospital of Pittsburgh of UPMC Involved in Projects To Develop Nations First Heart Assist Devices for Young Children 15888 3Healthy People 3A Healthy Planet Climate Change in LA 15885 1Healthy People 3A Healthy Planet Climate Change in LA 15885 2Healthy People 3A Healthy Planet Climate Change in LA 15885 3DCs Business Leaders Raise 243 3 Million at Annual Leukemia Ball Featuring Jay Leno 15882 1DCs Business Leaders Raise 243 3 Million at Annual Leukemia Ball Featuring Jay Leno 15882 2DCs Business Leaders Raise 243 3 Million at Annual Leukemia Ball Featuring Jay Leno 15882 3DCs Business Leaders Raise 243 3 Million at Annual Leukemia Ball Featuring Jay Leno 15882 4Governor Patrick Announces Life Sciences Initiative Victory With Organogenesis New Headquarters 4382 1Governor Patrick Announces Life Sciences Initiative Victory With Organogenesis New Headquarters 4382 2Governor Patrick Announces Life Sciences Initiative Victory With Organogenesis New Headquarters 4382 3Governor Patrick Announces Life Sciences Initiative Victory With Organogenesis New Headquarters 4382 4(Date:10/13/2008)...eading Content Rights Management System, Supports... Content Spend, WEST CHESTER, Pa., Oct. 13 /PRNew...ding global pharmaceutical manufacturer has integr...primary platform for the,secure distribution, data...cs for their new product video content. Imperium i...
(Date:10/13/2008)...swire/ -- The National Coalition for,Quality Color...ncerns over,the National CT Colonography Study pub...Medicine. The evidence must be closely evaluated, ...y is not without significant,potential risks. The ...py,remains the "Gold Standard" for colorectal canc...
(Date:10/13/2008)...blem in daily life, survey shows, PORTLAND, Ore.,...three-quarters of people living with psoriasis say...e, according to a National Psoriasis,Foundation 20...viduals with psoriasis and psoriatic arthritis,als...ly lives, shapes their,feelings about themselves a...
(Date:10/13/2008)...swire/ -- During the Pri-Med New York,conference a...are providers,took a 20-question quiz prepared by ...n Somerset, NJ. The quiz tested basic knowledge of..., EMR software, and healthcare,administration., T... The average number,of correct answers was only 7....
Breaking Medicine News(10 mins):Health News:Global Pharma Integrates Imperium(TM) to Support Launch Content ROI Initiatives! 2Health News:National Coalition for Quality Colorectal Cancer Screening and Care Conveys Concerns over CT Colonography 2Health News:National Coalition for Quality Colorectal Cancer Screening and Care Conveys Concerns over CT Colonography 3Health News:National Psoriasis Foundation Releases 2008 Study Results 2Health News:MTBC Practice Management Quiz Sends Message to Doctors: There is Real Room for Improvement or a Need to Outsource 2[0] Global Pharma Integrates Imperium(TM) to Support Launch Content ROI Initiatives![0] National Coalition for Quality Colorectal Cancer Screening and Care Conveys Concerns over CT Colonography[0] National Psoriasis Foundation Releases 2008 Study Results[0] MTBC Practice Management Quiz Sends Message to Doctors: There is Real Room for Improvement or a Need to Outsource
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