Potential in Biological Products

Mito Casp from BACHEM

Description:... A simultaneous dual parameter assay for mitochondrial membrane potential detection and poly caspase activity. Active caspases are detected by ... caspases within the cells. At the same time the mitochondrial membrane potential is visualized by a cell-permeable cationic red fluorescent dye which is ...
Company:BACHEM

ENGENISTM siRNA Test System from Yorkshire Bioscience Ltd

Description:... System is designed to provide a quantitative approach for evaluation of a potential of any DNA sequence to serve as an efficient target for RNA interference ... The ENGENISTM siRNA Test System allows for screening a large number of potential siRNA target sequences in simple transient transfection experiments, ...
Company:Yorkshire Bioscience Ltd

ProteoSpin Urine Protein Concentration Kit from Norgen Biotek Corporation

Description:... Urine protein analysis can be used for the identification of potential biomarkers in urine, and to diagnose and/or monitor renal and other ... large amounts, it provides an attractive alternative to blood plasma as a potential source of disease biomarkers. The ProteoSpin Urine Protein Concentration ...
Company:Norgen Biotek Corporation

Goat Anti-Cholesterol Oxidase Polyclonal Antibody, Unconjugated from GeneTex

Description:... exist as both type I and type II oxidases and are implicated in bacterial pathogenesis. In addition, they are important as clinical reagents, potential larvicides, and tools in cell ....
Company:GeneTex

Mouse Anti-Bovine Complex V (F1F0 ATP Synthase) Heart Mitochondria Monoclonal Antibody, Unconjugated, Clone 12F4AD8AF8 from MitoScience LLC

Description:... translational modifications including oxidative damage can be readily analyzed by proteomic approaches or antibody detection of these modifications. potential uses for the Complex V immunocapture kit include but are not limited to examining alterations of Complex V subunits in inherited mitochondrial ...
Company:MitoScience LLC

Panomer 9 random oligodeoxynucleotide, Alexa Fluor 647 conjugate from Molecular Probes (Invitrogen)

Description:... that are labeled at the 5' end with our proprietary Alexa Fluor dyes and they are useful for assessing microarray spot morphology, hybridization potential and channel bleedthrough on DNA ....
Company:Molecular Probes (Invitrogen)

Panomer 9 random oligodeoxynucleotide, QSY 7 conjugate from Molecular Probes (Invitrogen)

Description:... primers that are labeled at the 5' end with our proprietary QSY 7 dye and they are useful for assessing microarray spot morphology, hybridization potential and channel bleedthrough on DNA ....
Company:Molecular Probes (Invitrogen)

Neurobiology of Alzheimer's Disease from Promega

Description:... molecular nature of beta-amyloid and tau proteins, the role of apolipoprotein E and the use of transgenic models. The neurochemistry, in particular potential areas for pharmacological intervention are also ....
Company:Promega

Rabbit Anti-Kv4.2 Polyclonal Antibody, Unconjugated from GeneTex

Description:... yet tested in other species. Background Information In neurons voltage-dependent potassium channels are key determinants of the resting membrane potential and of membrane excitability, conditioning the frequency, and shape of action potential. Potassium channels are encoded by numerous genes whose ...
Company:GeneTex

FDSS6000 System from Hamamatsu Photonic Systems - Drug Discovery

Description:... service and support ensure instruments stay running through screening campaigns. Multiplexing dyes (Fura-2 AM and Fluo-4 AM or Fura-2 AM and Membrane potential dye) offer unique glimpses into physicochemical properties of your library compounds including quenching, autofluorescence, and acute ....
Company:Hamamatsu Photonic Systems - Drug Discovery

Ion Channel SpliceArray Service from ExonHit Therapeutics Inc.

Description:... the different alternatively spliced forms of the gene that are expressed in the samples under study. The GPCR SpliceArray monitors 1543 known and potential splice events derived from 441 GPCR genes. Splice events are profiled with a patent-protected combination of exon and junction probes that allow ...
Company:ExonHit Therapeutics Inc.

Apoptosis Pathway SpliceArrays from ExonHit Therapeutics Inc.

Description:... spliced forms of the gene that are expressed in the samples under study. The Apoptosis and Cell Death SpliceArray monitors 5806 known and potential splice events derived from 609 genes. Splice events are profiled with a patent-protected combination of exon and junction probes that allow robust, ...
Company:ExonHit Therapeutics Inc.

GPCR SpliceArray Service from ExonHit Therapeutics Inc.

Description:... the different alternatively spliced forms of the gene that are expressed in the samples under study. The GPCR SpliceArray monitors 1543 known and potential splice events derived from 441 GPCR genes. Splice events are profiled with a patent-protected combination of exon and junction probes that allow ...
Company:ExonHit Therapeutics Inc.

MitoLightApoptosis Detection Kit from CHEMICON

Description:... Disruption of the mitochondrial transmembrane potential is one of the earliest intracellular events that occur following induction of apoptosis. The MitoLight Apoptosis Detection Kit utilizes a lipophilic ...
Company:CHEMICON

MitoLight Mitochondrial Apoptosis Detection Kit from CHEMICON

Description:... Disruption of the mitochondrial transmembrane potential is one of the earliest intracellular events that occur following induction of apoptosis. The MitoLight Apoptosis Detection Kit utilizes a lipophilic ...
Company:CHEMICON

Shimadzu Phoretix 2D from Shimadzu Biotech

Description:... spot filtering function (to focus on areas of interest). For gel comparison a tool kit has been designed to highlight specific elements of the gel of potential biological significance. Parameters for automatic spot detection are easily entered using the set-up wizard. Background subtraction is ...
Company:Shimadzu Biotech

ATTO-TAG CBQCA Amine-Derivatization Kit from Molecular Probes (Invitrogen)

Description:... conjugates should be in the attomole range (10-18 moles). The high sensitivity, freedom from background and long-wavelength excitability make these potential reagents for research, diagnostic and forensic applications, including drug analysis. The ATTO-TAG reagents can, of course, be used in HPLC and other ...
Company:Molecular Probes (Invitrogen)

ATTO-TAG CBQCA derivatization reagent (CBQCA; 3-(4-carboxybenzoyl)quinoline-2-carboxaldehyde) from Molecular Probes (Invitrogen)

Description:... conjugates should be in the attomole range (10-18 moles). The high sensitivity, freedom from background and long-wavelength excitability make these potential reagents for research, diagnostic and forensic applications, including drug analysis. The ATTO-TAG reagents can, of course, be used in HPLC and other ...
Company:Molecular Probes (Invitrogen)

ATTO-TAG FQ Amine-Derivatization Kit from Molecular Probes (Invitrogen)

Description:... conjugates should be in the attomole range (10-18 moles). The high sensitivity, freedom from background and long-wavelength excitability make these potential reagents for research, diagnostic and forensic applications, including drug analysis. The ATTO-TAG reagents can, of course, be used in HPLC and other ...
Company:Molecular Probes (Invitrogen)

BlockAid blocking solution *for use with microspheres* from Molecular Probes (Invitrogen)

Description:... Molecular Probes intensely fluorescent and highly photostable FluoSpheres microspheres have enormous potential for use in a variety of applications requiring probes that can deliver a strong signal. Unfortunately, protein- and other macromolecule-labeled ...
Company:Molecular Probes (Invitrogen)

Sterilizing UV PCR Workstation from UVP

Description:... Sterilizing UV PCR Workstation creates an ideal environment for preparing PCR and other samples by reducing the chance of DNA contamination Control potential PCR contamination with the built-in high intensity UV tubes for inactivation of DNA between experiments The ultraviolet irradiation can be used as ...
Company:UVP

Neural Stem Cell Expansion Kit - Monolayer from R&D Systems

Description:... as identified after growth factor withdrawal by staining with the antibodies Tuj1, O4 and anti-GFAP, respectively. Neural stem cells (NSCs), with the potential to self-renew and to differentiate into neurons and glial cells, have been isolated from different regions of the developing and adult brain (1 - 6). ...
Company:R&D Systems

Neural Stem Cell Expansion Kit - Neurosphere from R&D Systems

Description:... as identified after growth factor withdrawal by staining with the antibodies Tuj1, O4 and anti-GFAP, respectively. Neural stem cells (NSCs), with the potential to self-renew and to differentiate into neurons and glial cells, have been isolated from different regions of the developing and adult brain (1 - 6). ...
Company:R&D Systems

Neural Stem Cell Expansion Kit - Monolayer Plus from R&D Systems

Description:... as identified after growth factor withdrawal by staining with the antibodies Tuj1, O4 and anti-GFAP, respectively. Neural stem cells (NSCs), with the potential to self-renew and to differentiate into neurons and glial cells, have been isolated from different regions of the developing and adult brain (1 - 6). ...
Company:R&D Systems

MIDAS TRAQ System with 4000 Q TRAP LC/MS/MS System from Applied Biosystems

Description:... The workflow for biomarker verification overcomes the need for separate methods development, including protein or peptide standards, for each potential biomarker. Quantitatively Validate Candidate Biomarkers without Western Blots or Immunoassays After candidate verification, the resulting assays ...
Company:Applied Biosystems

PolarScreen PPARGamma-Competitor Assay Kit, Red from Molecular Probes (Invitrogen)

Description:... Proliferator-Activated Receptor-gamma (PPARGamma) Competitor Assay Kits provide a sensitive and efficient method for studying and screening potential PPARGamma ligands using fluorescence polarization (FP). The kit contains human PPARGamma-Ligand binding domain (PPARGamma-LBD) with an N-terminal ...
Company:Molecular Probes (Invitrogen)

Metabolic Profiler from Bruker Daltonics

Description:... like: Assessment of the metabolic profile of a living organism to distinguish between normal and altered states Discovery and identification of potential biomarkers Study mechanism of drug induced toxicity and/or efficacy at pre-clinical or clinical stages of development Research in ...
Company:Bruker Daltonics

PicTure - Double Staining Kit from Invitrogen

Description:... to provide excellent sensitivity. In addition, PicTure™-Double Staining does not contain biotin or streptavidin and uses only Fab fragments, so potential background due to endogenous biotin activity or Fc receptors is completely avoided.PicTure™-Double Staining kit utilizes two distinct ...
Company:Invitrogen

APO LOGIX - JC-1 Mitochondrial Membrane Potential Detection Kit from BACHEM

Description:... is typically defined as a collapse in the electrochemical gradient across the mitochondrial membrane, as measured by the change in the membrane potential (YD). Loss of mitochondrial YD is indicative of apoptosis and can be detected by a unique fluorescent cationic dye, ...
Company:BACHEM

NOVOstar Microplate Reader from BMG LABTECH

Description:... response curve by measuring a wide range of analyte concentrations. Applications that the NOVOstar is targeted for include: Ca2+ uptake membrane potential studies intracellular pH measurement of intracellular ionic changes fluorescent reporter gene assays traditional fluorescence assays involving up ...
Company:BMG LABTECH

Isolated Mitochondria Staining Kit from Sigma-Aldrich

Description:... the detection of changes in mitochondrial inner-membrane electrochemical potential Contains the antibiotic Valinomycin that permeabilizes the mitochondrial ... aggregates. Any event that dissipates the mitochondrial membrane potential (e.g. apoptosis) does not allow the accumulation of JC-1 dye in the ...
Company:Sigma-Aldrich

Cell invasion Fluorometric (green) Assay Kit, InnoCyte™ from Calbiochem

Description:... 96-well Cell Invasion Assay is designed to determine the invasive capacity of cells using laminin as a significant barrier to invasion or to screen potential anti-metastatic agents in vitro in a convenient, high-throughput, 96-well format. The 8 mm pore size is appropriate for all types of adherent cells ...
Company:Calbiochem

CiphergenExpress Software from Ciphergen

Description:... powerful, advanced data mining and analysis capabilities for rapid, automated analysis of multiple experiments over multiple conditions to identify potential biomarkers. CiphergenExpress Features Robust, client-server database centralizes data Relational database ensures data integrity Intuitive ...
Company:Ciphergen

CNS Side Effect Profile (CNS SEP) from Novascreen-a Caliper Life Sciences Company

Description:... tested through a broad panel of 38 ligand binding and enzyme assays targeting the Central Nervous System. Used to determine selecitivty and potential CNS-Side Effect liabilities of ....
Company:Novascreen-a Caliper Life Sciences Company

General Side Effect Profile I (GEN SEP I) from Novascreen-a Caliper Life Sciences Company

Description:... spanning a broad therapeutic range. This assay panel includes many non human tissue sources and several non-selective assays. Used to determine potential side-effect liabilities of ....
Company:Novascreen-a Caliper Life Sciences Company

Cardiovascular/Renal Profile from Novascreen-a Caliper Life Sciences Company

Description:... tested through a broad panel of 38 ligand binding and enzyme assays targeting the Central Nervous System. Used to determine selectivity and potential CV/Renal liabilities of ....
Company:Novascreen-a Caliper Life Sciences Company

Gastrointestinal Profile from Novascreen-a Caliper Life Sciences Company

Description:... tested through a broad panel of 38 ligand binding and enzyme assays targeting the Central Nervous System. Used to determine selectivity and potential GI liabilities of ....
Company:Novascreen-a Caliper Life Sciences Company

Neurological Profile from Novascreen-a Caliper Life Sciences Company

Description:... tested through a broad panel of 38 ligand binding and enzyme assays targeting the Central Nervous System. Used to determine selectivity and potential Neurological liabilities of ....
Company:Novascreen-a Caliper Life Sciences Company

PPARGamma-Competitor Assay Kit Green from Invitrogen

Description:... Proliferator-Activated Receptor-gamma (PPAR) Competitor Assay Kit, Green provides a sensitive and efficient method for studying and screening potential PPAR ligands using fluorescence polarization (FP). The kit contains human PPAR 1-ligand binding domain (PPAR-LBD) with an N-terminal His-tag and a ...
Company:Invitrogen

15(R)-17-phenyl trinor Prostaglandin F2alpha isopropyl ester from Cayman Chemical

Description:... at 13,14 and an inverted (β) hydroxyl group at C-15. Similar to 15(S)-latanoprost, 15(R)-17-phenyl trinor PGF2α isopropyl ester is a potential impurity in most commercial preparations of the latanoprost bulk drug product. The IC50 values for the free acid forms of 15(S)-17-phenyl trinor ...
Company:Cayman Chemical