Anti-JIP 1 / 2 (SH3) Polyclonal Antibody, Unconjugated, Clone ZMD.177 from Invitrogen
...use brain. Taken together with previous reports of active JNK in the brains of Alzheimers disease patients, this evidence suggests that the JNK signaling pathway, and thus the scaffolding function of JIP1, may be fundamental to the progression of Alzheimers disease....Routine Testing Laboratory from AAIPharma Inc.
...ent and method validation Testing of formulations, active pharmaceutical ingredients (APIs) and excipients, finished products, in-process and stability samples Flexible service arrangements customized to your methodologies Support for new products from concept to filing Consulting services to guide testing ...Digital Clamp One from myNeuroLab.com
...mulate a quiescent neuron whenever a different and active neuron fires, forcing it to fire. One neuron can drive another through the Digital Clamp One. It has also been used in the multiplex mode to stimulate and record through one electrode, making possible a single electrode clamping experiment. An of c...Mitochondria Isolation Kit for Tissue and Cultured Cells from BioChain
... Isolation Kit is designed to isolating intact and active mitochondria in a fast and easy way. One kit is consisted of reagents enough for performing 100 isolations (enriching mitochondria from 10 20 g tissue or from 1x10 10 5x10 10 cells)....Porcine Leptin ELISA Kit from Diagnostic Systems Laboratories, Inc.
... well as its involvement in endocrine function are active areas of research. While the future for leptin as a therapeutic agent is not clear, its involvement in many areas of physiology undoubtedly makes this a new hormone which will require extensive study in the next few years to understand its physiolog...SlowFade Antifade Kit from Molecular Probes (Invitrogen)
The active ingredient in Molecular Probes. SlowFadeAntifade Kits is 1,4-diazabicyclo[2.2.2]octane (DABCO), which appears to act as a free radical scavenger that extends useful fluorescence emission. Our original SlowFade formulation (S-2828) was designed to red...PolarScreen Androgen Receptor Competitor Assay Kit, Red from Molecular Probes (Invitrogen)
...n Receptor Competitor Assay Kits include purified, active AR-LBD (His-GST) protein, Fluormone AL Green ligand (green assay kit) or Fluormone AL Red ligand (red assay kit), and buffer. Store components as indicated in the assay protocol (-80C, -20C, or +4C)....PPARGamma-Competitor Assay Kit Green from Invitrogen
...PAR-Competitor Assay Kit, Green includes purified, active PPAR-LBD protein, Fluormone PPAR Green ligand, and assay buffer...ABsolute QPCR SYBR Green ROX Mix from ABgene
... 2x QPCR SYBR Green Mix contains optimal levels of active SYBR Green I dye and Thermo-Start DNA Polymerase s...o-Start DNA Polymerase Optimised buffer containing active SYBR Green I Reproducibility All mixes undergo extensive QC to ensure batch to batch consistency Br...AChE Bioluminescence Assay Kit, aCella from BACHEM
...oupled enzyme reactions translates the presence of active AChE into a change in luminescence. Inhibitors of AChE are readily detected by an increased luminescence, which is caused by the consumption of ATP. The assay can be adapted for high throughput screening. Application: Luminometer....Fragment-based Screening Services from ActiveSight
...involves the binding of drug-like fragments to the active sites of crystallized protein drug targets, allowing scientists to develop novel, high-affinity inhibitors. Relying on state-of-the-art Rigaku X-ray crystallography automation, ActiveSight can screen up to 100 protein structures a day for pharmaceuti...FLAG Immunoprecipitation Kit from Sigma-Aldrich
...nd efficient immunoprecipitation and elution of an active FLAG-tagged protein. The immunoprecipitation is performed with ANTI-FLAG-M2 affinity gel, which is a highly specific monoclonal antibody covalently attached to agarose resin. The use of affinity resin allows an efficient binding of FLAG-tagged protei...Digital Clamp One Electrophysiology Feedback Unit from myNeuroLab.com
...mulate a quiescent neuron whenever a different and active neuron fires, forcing it to fire. One neuron can drive another through the Digital Clamp One. It has also been used in the multiplex mode to stimulate and record through one electrode, making possible a single electrode clamping experiment....Factor B-depleted serum from Quidel
...or the detection and quantitation of hemolytically active complement components. Depleted sera have been used to assess complement activation in non-human species. A copy of the monograph "Quantitation of C3 activity in Murine Sera by Hemolytic Assay "is available from Quidel's technical service department....CaspaTag™ Pan-Caspase In Situ Assay Kit, Sulforhodamine from CHEMICON
... Kit is a fluorescent-based assay for detection of active caspases in cells undergoing apoptosis. The kit is... In Situ Assay Kits use a novel approach to detect active caspases. The methodology is based on Fluorochrome Inhibitors of Caspases (FLICA). The inhibitors ar...CaspaTag™ Pan-Caspase In Situ Assay Kit, Fluorescein from CHEMICON
...cein is a fluorescent-based assay for detection of active caspases in cells undergoing apoptosis. The kit is...pase Detection Kits use a novel approach to detect active caspases. The methodology is based on Fluorochrome Inhibitors of Caspases (FLICA). The inhibitors ar...PolarScreen PPARGamma-Competitor Assay Kit, Red from Molecular Probes (Invitrogen)
...PARGamma Competitor Assay Kits, includes purified, active PPARGamma-LBD protein, Fluormone PPARGamma Green ligand kit) or Fluormone PPARGamma Red ligand (red assay kit), and assay buffer. Store components as indicated in the assay protocol....Tfi DNA Ligase, 2,000U, thermostable from Bioneer, Inc.
...y strand at 45 - 65?. Tfi DNA Ligase is stable and active at much higher temperatures than conventional DNA ligases, Thus, Tfi DNA Ligase is the ideal enzyme for applications the require high-temperature, high-stringency ligation of duplex DNA molecules....AmpliTaq Gold DNA Polymerase from Applied Biosystems
...s cleaved during a heat activation step, releasing active AmpliTaq® DNA enzyme. The yield of specific p...enzyme's chemical hot-start capability can release active enzyme in a "time-release" manner. With or without a limited up-front heat activation step, active e...DNA Exonuclease III , E. coli from EPICENTRE Biotechnologies
... the desired excision rate. Exonuclease III is not active on 3'-protruding ends of 4 bases or more in length, single-stranded DNA, or on thioester-linked nucleotides. The enzyme also has intrinsic RNase H, 3'-DNA phosphatase, and apurinic DNA endonuclease activities....Calf Topoisomerase I from USB Corp.
...ir by gel electrophoresis (3) . Topoisomerase I is active in the absence of Mn 2+ and can be used in solutions containing EDTA. Purity: Tested for contaminating endonucleases and exonucleases. Storage Buffer: 20mM potassium phosphate (pH 7.2), 50mM KCl, 0.05mM EDTA, 5mM 2-mercaptoethanol, 0.02% BSA...SuperScript II RNase H- Reverse Transcriptase from Invitrogen
...nt mutations rather than a deletion in the RNase H active center. Like SuperScript™ RT SuperScript™ II RT has 106- to 107-fold reduced RNase H activity. Unlike SuperScript™ RT however the selective mutations within the RNase H domain maintain full polymerase activity. This structural modif...SuperScript II RNase H- Reverse Transcriptase from Invitrogen
...nt mutations rather than a deletion in the RNase H active center. Like SuperScript™ RT SuperScript™ II RT has 106- to 107-fold reduced RNase H activity. Unlike SuperScript™ RT however the selective mutations within the RNase H domain maintain full polymerase activity. This structural modif...Human TRAP 5 ImmunoCapture Assay Kit from BioVendor Laboratory Medicine, Inc.
...tended for the determination of human enzymaticaly active TRAP 5 (Tartrate Resistant Acid Phosphatase 5, TRACP 5) in serum and plasma....GeneAmp PCR Carry-over Prevention Kit from Applied Biosystems
...g abasic polynucleotide with heat. Although UNG is active on single- and double-stranded dU-containing DNA,2 ribouracil residues in RNA and dUTP itself are not substrates for UNG.3 AmpliTaq and AmpliTaq Gold DNA polymerase, and the other components of the PCR reaction mixture remain intact during UNG treatm......robust interaction with RNase and does not release active RNase in the absence of DTT or other reducing agents. ANTI-RNase may be used in any application where placental ribonuclease inhibitor is used. It is ideal for use in in vitro transcription and translation, cDNA synthesis PCR, RT-PCR, RNA isolation p......e robust interaction with RNases, does not release active RNases in the absence of DTT, and inhibits a broad...ase or Taq polymerase. Additionally, SUPERaseIn is active up to 65C and for a pH range of 5.5 to 8.5....Taq DNA Polymerase -Klein Taq from AppliChem GmbH
...ymerase-encoding gene. The enzyme reveals a highly active and even more heat-stable DNA polymerase activity in comparison with Taq DNA polymerase. The optimal range of the Mg2+ concentration for Klein Taq is broader than that for the majority of thermostable polymerases. This feature permits to optimize rea...Px2 Thermal Cycler from Thermo Scientific
...s for precision temperature control, including our active tube control for in sample measurement. In addition, it is offered with a choice of six interchangeable blocks, including the latest gradient cycling format. Features: Accurate temperature control for optimal PCR performance Gradient capability ...Tritirachium album Proteinase K from USB Corp.
...ium album Description: Proteinase K is a highly active and stable endopeptidase used in a wide range of applications purified from the fungus T. album. It cleaves peptide bonds mainly following the carboxyl group of N-substituted hydrophobic aliphatic and aromatic amino acids (1) and is classified as a ...Rabbit Anti-Peroxiredoxin 1 Polyclonal Antibody, Unconjugated from GeneTex
...ogy, particularly amino-terminal region containing active site cysteine residue, and the thiolspecific antioxidant activity, distribute throughout all the kingdoms. Among them, mammalian Prx consists of 6 different members grouped into typical 2-Cys, atypical 2-Cys Prx, and 1-Cys Prx. Except Prx6 belonging ...Human Caspase-7 from Calbiochem
ICE-LAP3 Mch3 Lyophilized solid. Highly active enzyme useful for the study of enzyme regulation and kinetics, cleavage of target substrates, and inhibitor screening. Specific activity: 15,000 units/mg protein. One unit is defined as the amount of enzyme that will cleave 1 nmol of Ac-DEVD-pNA...Rabbit Anti-Human CELSR3 Polyclonal Antibody, Unconjugated from GeneTex
...s gene is expressed during development at sites of active neurogenesis and in adult mice and rats in brain, spinal cord, dorsal root ganglion, and eye. ESTs have been isolated from human B-cell/lung/testis, blood, brain, colon, heart/melanocyte/uterus, lung, nerve, and placenta libraries. Immunogen: Synt......CM Caps contain ridges at the bottom that keep the active capture area of the cap twelve microns off the surface of the sample. This separation ensures the precise capture of up to several hundreds of cells. In addition, the CapSure LCM Caps work with ExtracSure devices that minimize the dilution of biolog......CM Caps contain ridges at the bottom that keep the active capture area of the cap twelve microns off the surface of the sample. This separation ensures the precise capture of up to several hundreds of cells. In addition, the CapSure LCM Caps work with ExtracSure devices that minimize the dilution of biolog......CM Caps contain ridges at the bottom that keep the active capture area of the cap twelve microns off the surface of the sample. This separation ensures the precise capture of up to several hundreds of cells. In addition, the CapSure LCM Caps work with ExtracSure devices that minimize the dilution of biolog...ChemiArray Mouse Lysate Angiogenesis Antibody Array I , 25 cytokines per membrane from CHEMICON
...cons systems present a more accurate reflection of active cytokine levels because they only detect secreted cytokines, and no amplification step is needed. Furthermore, it is simpler, faster, environmentally friendlier, and more sensitive. By using the ChemiArray platform, scientists can rapidly and accurat...FAM Poly Caspase Assay Kit from B-Bridge International
...e residue that resides on the large subunit of the active caspase heterodimer, thereby inhibiting further en...escent signal is a direct measure of the number of active caspase enzymes that were present in the cell at the time the reagent was added. Cells that contain...Eppendorf Thermomixer R from Eppendorf North America
...ns that require shaking, heating, and cooling. Its active heating/cooling function has greatly expanded its application and temperature control ranges. Five different thermoblocks, which can each accommodate 24 micro test tubes, are available for: 0.5 ml, 1.5 ml, and 2.0 ml volumes; microplates of all well ......ture range: 5C above ambient up to +60C Optional active cooling allows temperatures down to 10C below ambient (at maximum ambient of +32C) Maximum capacity: four 3000 ml Erlenmeyer flasks Internal spill tray as standard Programmable process parameters: time, temperature and rpm up to 5 programs...StabilZyme SELECT Stabilizer from SurModics, Inc.
...lizer is a diluent and stabilizer for biologically active components in solution, and is recommended for stabilizing protein/serum controls, HRP-hapten conjugates used in competitive assays, and applications where background is a problem. The shelf-life of StabilZyme SELECT Stabilizer is 2.5 years when sto......ermeable, non-cytotoxic and bind covalently to the active caspases within the cells. At the same time the mitochondrial membrane potential is visualized by a cell-permeable cationic red fluorescent dye which is accumulated by the mitochondria of healthy but not apoptotic cells. The kit can be used in conjun...Bio-Beads SM-2 Macroporous Beads, 100 g from Bio-Rad
...r the adsorption of nonpolar substances or surface active agents; for example, the removal of detergents such as Triton X-100 and organics such as polyaromatic hydrocarbons from water. Bead size is 300-1,180 micrometers. Supplied as 100 g....In Situ Pan-Caspase Assay Kit, Sulforhodamine from CHEMICON
...stream regulatory events (initiator caspases). An active caspase consists of two large and two small subunits that form two heterodimers which associate in a tetramer. In common with other proteases, caspases are synthesized as precursors that undergo proteolytic maturation, either autocatalytically or in...In Situ Pan-Caspase Assay Kit from CHEMICON
...stream regulatory events (initiator caspases). An active caspase consists of two large and two small subunits that form two heterodimers which associate in a tetramer. In common with other proteases, caspases are synthesized as precursors that undergo proteolytic maturation, either autocatalytically or in...Eppendorf Thermomixer R from Eppendorf North America
...ns that require shaking, heating, and cooling. Its active heating/cooling function has greatly expanded its application and temperature control ranges. Five different thermoblocks, which can each accommodate 24 micro test tubes, are available for: 0.5 ml, 1.5 ml, and 2.0 ml volumes; microplates of all well ...Rabbit Anti-HDAC4 Polyclonal Antibody, Unconjugated from GeneTex
...n the nucleus and cytoplasm in a process involving active nuclear export. Association of HDAC4 with 14-3-3 results in sequestration of HDAC 4 protein in the cytoplasm. In the nucleus, HDAC4 associates with the myocyte enhancer factor MEF2A. Binding of HDAC4 to MEF2A results in the repression of MEF2A transc...Rabbit Anti-Human MMP-14 / MT1-MMP Antibody, Unconjugated from Lab Vision
...ogelatinase A (MMP-2) and progelatinase B to their active forms. MT1-MMP gets activated through the membrane... forming a trimer. It cleaves the pro-MMP-2 to its active form. Antigen: A synthetic peptide derived from aa 160-173 of human MMP-14 protein. This antib...Human Apoptosis Kit 50 tests from BD Biosciences Pharmingen
... to quantitatively measurecleaved PARP, Bcl-2, and active Caspase-3 protein levels in a single sample. TheKit performance has been optimized for analysis of specific protein in cell lysates.......The immunocapture antibody isolates a functionally active complex and a protocol has been described for measuring this activity while the enzyme is still bound to the capture beads or fixed in a 96 well plate. Tightly bound kinases and phosphatases are retained on the complex through the immunocapture step....... dark blue formazan product. This process requires active mitochondria, and even freshly dead cells do not cleave significant amounts of MTT. Reagent A is a component of Chemicons MTT assay kit, Catalog Number CT01/CT02....StabilZyme NOBLE BSA-Free Stabilizer from SurModics, Inc.
...ilizer is recommended for stabilizing biologically active components in solution, such as protein/serum controls, HRP-hapten conjugates used in competitive assays, and applications where background is a problem. The shelf-life of StabilZyme NOBLE Stabilizer is 2 years when stored at 4C. Product samples av...Dynabeads Mouse Pan B (B220) from Dynal Biotech
...ntigen is expressed on mouse B cells and lytically active subsets of lymphokine activated killer cells from all common mouse strains...Human MMP-3 Assay Kit from GE Healthcare, formerly Amersham Biosciences
...ISA.Specific for total MMP-3: Recognizes proMMP-3, active MMP-3 and complexed MMP-3. No cross-reactivity with MMP-1, -2, -9. Range: 3.75-120 ng/ml. Sensitivity: 2.35 ng/ml.Suitable for use with cell culture supernatant, serum, plasma and tissue samples.~ 4-h protocol.Store at -15 to -30 C. Category: Drug S...Calf Alkaline Phosphatase, Calf Intestinal, Unconjugated from Promega
...ith [32P]ATP and T4 Polynucleotide Kinase. CIAP is active on 5 overhangs, 5 recessed and blunt ends (15)....Casein Kinase 1 Active from Upstate
Casein Kinase 1, active MW: 34.2kDa Formulation: 10mM HEPES, pH 7.4, 150mM NaCl, 0.02% Brij-35, 1mM dithiothreitiol with 50% glycerol Properites: For Specific Activity data, refer to the Certificate of Analysis for individual lots of enzyme. Purification: ammonium salt prec...Origami(DE3)pLysS Glycerol Stock from Novagen
...at expression in Origami(DE3) yielded 10-fold more active protein than in another host even though overall expression levels were similar (1). Origami hosts are compatible with ampicillin-resistant plasmids and are ideal for use with pET-32 vectors, since the thioredoxin fusion tag further enhances the form...Origami(DE3) Glycerol Stock from Novagen
...at expression in Origami(DE3) yielded 10-fold more active protein than in another host even though overall expression levels were similar (1). Origami hosts are compatible with ampicillin-resistant plasmids and are ideal for use with pET-32 vectors, since the thioredoxin fusion tag further enhances the form...Rabbit Anti-Ki67 Polyclonal Antibody, Unconjugated from GeneTex
...ressed by proliferating cells in all phases of the active cell cycle (G1, S, G2 and M phase). It is absent in resting (G0) cells. Ki67 antibodies are useful in establishing the cell growing fraction in neoplasms (immunohistochemically quantified by determining the number of Ki67-positive cells among the tot...Anti-MMP-13 Collagenase-3, amino terminal end of active enzyme; rabbit host...