Vector in Biological News

Amarna Therapeutics B.V. and TNO announce SVac research and development partnership

... a revolutionary novel viral gene delivery vector platform technology SVac for producing human ... the extremely important therapeutic area of viral vector and gene delivery technologies and is yet another ... therapeutics is the SVac viral gene delivery vector platform, which provides sensational characters ...

IVCC and Syngenta start project for novel insecticidal active ingredient for malaria control

... has increased significantly its activities in the vector Control area since 2008. We are really excited ... project with IVCC," said Frdric Baur, Global Head vector Control at Syngenta. "It represents a key ... project will accelerate the development of new vector control products, which benefit communities where ...

UF researchers develop improved gene therapy agent

... and doctors using AAV as a gene therapy vector how to administer enough of the gene-toting ... was working 29 times better than the standard vector was at incorporating the new gene into cells, at ... goal of creating what Srivastava calls a perfect vector that lacks all seven phosphate-attracting ...

U. Mass Medical School and Carnegie announce licensing agreements with Oxford BioMedica

... using lentiviral vectors. A lentiviral vector is based on a type of virus that infects dividing ... opportunities presented by Oxfords lentiviral vector delivery technology is intriguing to us. We have ... on their established broad IP in the lentiviral vector delivery space. Our hope is to see the further ...

UMMS and CIW grant key RNAi rights to Oxford Biomedica

... using lentiviral vectors. A lentiviral vector is based on a type of virus that infects dividing ... opportunities presented by Oxfords lentiviral vector delivery technology is intriguing to us. We have ... on their established broad IP in the lentiviral vector delivery space. Our hope is to see the further ...

New screening strategy for detection of chagas disease in children

... interrupting the transmission of T. cruzi through vector control measures (such as insecticide spraying), ... a peri-urban community of Arequipa, Peru, where a vector control campaign is currently disrupting ... to data that had been collected during the vector control campaign (entomological, spatial, and ...

Pennsylvania Hospital surgeon receives grant to develop molecular cardiac surgery

... causing heart failure. A carrier called a vector is used to deliver the specially designed beneficial genes (transgenes). The most common vector is a virus that has been genetically altered. ... the virus and inserting therapeutic genes. The vector then discharges the therapeutic genes into the ...

USDA Cooperative Agreement funds mosquito project at Rutgers

... New Brunswick, NJThe Center for vector Biology at Rutgers New Jersey Experiment Station ... this mosquito as an efficient laboratory vector of more than thirty arboviruses, in particular ... and even yellow fever. We created the Center for vector Biology at NJAES in 2006 to address these types ...

A genetic identity card for Plasmodium populations to improve control strategies

... distribution of parasite oocysts in the mosquito vector guts. The set of data corroborated those acquired ... reproduction strategy is the same in the two vector species investigated. One of the approaches ... the progressive eradication of its principal vector Anopheles gambiae. To achieve this some ...

Penn-Wistar team gains insight into HIV vaccine failure

... immunity in the form of neutralizing antibodies to the adenovirus 5 (Ad5) vector used to deliver the vaccine actually showed a trend toward an increased ... been taken from participants at baseline, before administration of the Ad5 vector vaccine under study. From their current Ad5 assay, the team found no ...

P[acman]-generated fruit fly gene 'library': A new research tool

... allows scientists to study large chunks of DNA in living flies. The vector officially P/phiC31 artificial chromosome for manipulation combines ... site using phiC31-mediated transgenesis. Venken adapted the P[acman] vector to create genomic libraries, so that a researcher can choose a gene and ...

UC Riverside professor receives top scientific honor

... internationally for his significant contributions to insect science and vector biology. A leader in insect and mosquito reproduction and immunity, he is ... to see that the NAS recognizes the importance of insect science and vector biology by honoring a researcher in this field," he said. "I am deeply ...

Entomological Society of America names 2008 award winners

... on the abundance of adult female mosquitoes and the relationship between vector abundance and arboviral transmission. Chris has received a number of awards, including the William C. Reeves Award from the Mosquito and vector Control Association of California, the Hazeltine Student Research ...

Vega main engine test in Kourou

... nozzle joint is more flexible than on previous engines, allowing thrust vector control by means of electromechanical actuators. This is an additional ... industrial subcontractors involved in the P80 are SABCA of Belgium (thrust vector control system), Snecma Propulsion Solide of France (nozzle) and APP of ...

Nanoparticle-delivered 'suicide' genes slowed ovarian tumor growth

... colleagues at the Massachusetts Institute of Technology evaluated the therapeutic efficacy of a cationic biodegradable beta-amino ester polymer as a vector for the nanoparticle delivery of a DNA encoding diphtheria toxin suicide gene. These nanoparticles were injected into mice with primary or metastatic ...

Researchers develop 'brain-reading' methods

... the word dog is likely to draw up a memory of a pet, the same as reading a story about a dog would. Using machine learning techniques (a support vector machine), capable of analyzing and categorizing large amounts of data, the researchers were able to identify those slight differences that allowed ...

$1.6 million grant to lead development of resistance-detecting field kit

... tools will provide information vital for predicting the success of IRS and ITN programmes. Project leader Dr Martin Donnelly, Senior Lecturer in vector Biology at LSTM said: "Malaria control in Africa is reliant upon the use of insecticides against mosquitoes. Therefore if the mosquitoes develop high ...

DNA barcoding of mosquito species deployed in bid to end elephantiasis

... therefore, where the drug strategy needs to be supplemented with insecticides to successfully eliminate LF. Prof. Boakye also notes that blanket vector control using insecticides can have serious impact on non-target organisms, leading to biodiversity loss. The additional information and insights ...

Symposia selected for Entomological Society of America meeting

... the Social Insects Insect Scientist/Plant Breeder Interactions: Working Together Towards Host Plant Resistance in Soybeans Plant Disease vector Movement and Spatial Dynamics in Greenhouse and Cropping Systems Pollinator Diversity in Urban, Agricultural, and Native Landscapes ...

American Chemical Society Weekly PressPac -- April 1, 2009

... ARTICLE: http://pubs.acs.org/stoken/presspac/presspac/full/10.1021/pr8008429 CONTACT: Jos M.C. Ribeiro, M.D., Ph.D. Laboratory of Malaria and vector Research National Institute of Allergy and Infectious Diseases Rockville, Md. 20852 Phone: 301-496-9389 Fax: 301-480-2571 Email: ...

Cause of mussel poisoning identified

... and the chemist Dr. Bernd Krock from the Alfred Wegener Institute for Polar and Marine Research were able to show that Protoperidinium is only the vector and not the producer of the toxins, just like other voracious protozoa and mussels. They isolated a small alga from the North Sea off the Scottish ...

Human beta cells can be easily induced to replicate, according to study in Diabetes

... that, unlike rodents, human beta cells contain a significant amount of a protein called cdk-6. When cdk-6 production was increased using a viral vector carrying the cdk-6 gene, the cells replicated. Stimulation was further enhanced by increasing production of another cell cycle molecule called cyclin ...

Single virus used to convert adult cells to embryonic stem cell-like cells

... has made the proteins for all four genes. Using the tandem genes, Carey created iPS cells containing just a single copy of the polycistronic vector instead of multiple integrations of the viruses. This significant advancement indicates that the approach can become even safer if combined with ...

Caltech researchers get first look at how groups of cells coordinate their movements

... to take that data and make sense of it." Making sense of the data meant reducing the movement of each cell to a vector, and then analyzing that vector not just along its x, y, and z axes, but by looking at its cylindrical coordinates. "The spreading has both an angular and a radial component," ...

Innovations in Pediatric Medicine International Conference brings together pediatrics experts

... providing evidence that the approach can be effective and could be used to treat other genetic diseases of blood cells. One challenge is the viral vector used to introduce the gene has been linked to cancer. In response, new vectors are being designed. Dr. Gary Fleisher of the Children's Hospital ...

New journal shows half-broken gene is enough to cause cancer

... by James Lupski and colleagues that deals with mechanisms for human genomic rearrangements and a groundbreaking piece on the methodology of knock-in vector construction by Nicholas Hastie and colleagues. According to Antonarakis, "Given its unique characteristics, PathoGenetics is likely to become the ...

Gene therapy restores vision to mice with retinal degeneration

... usually produced in a subset of cells that are involved with establishing circadian rhythms but not with vision. The MGH team used the standard viral vector adeno-associated virus to deliver the gene encoding melanopsin throughout the retinas of mice whose rod and cone photoreceptors had degenerated from ...

Sig-Tec(R) and BIO-key(R) Deliver Advanced Biometric Security Solution to Ohio County Law Enforcement Agency

... access management (IdAM) software solution for Strong Authentication and password management (AppStarter Single Sign On) integrated with BIO-key's vector Segment Technology(TM) (VST) toolset, for fingerprint biometrics capture and verification, authorized staff can now access the Mahoning County ...

Scientists use remote satellite imaging to predict outbreaks of infectious disease

... now beginning to understand infectious disease is a moving target," said Colwell. "As the climate shifts, any disease with an environmental stage or vector is going to be affected." Colwell will call for an integrated approach of global scientific paradigms to track and tackle infectious disease: "We ...

Entomological Society of America names new Fellows for 2008

... of Amazon Research in Manaus, Brazil. Subsequently, he has worked for the USDA Agricultural Research Service, the World Health Organization, and the vector Biology and Control Project (USAID) in the U.S., Latin America, West Africa, Europe, and several other regions of the world. His research has ...

No more big stink: scent lures mosquitoes, but humans can't smell it

... blood meal and thus, more opportunity to become infected." By monitoring gravid traps containing West Nile virus-infected mosquitoes, mosquito and vector control districts and health officials can determine when it is time to spray. Leal said that another advantage of the gravid traps is that with ...

USGS news: August science picks

... of weekly mosquito abundance records from California's comprehensive mosquito surveillance program. To read the report published in the Journal of vector Ecology, visit http://www.sove.org/Journal%20PDF/June%202008/11-Reisen%20et%20al%2007-81.pdf . For more information, contact Dan Cayan at ...

Midge-hunting scientists tackle spread of devastating bluetongue virus

... but we know that we couldn't have achieved this without the effort and knowledge of the scientists at IAH. Bluetongue shares its transmission vector - the midge - with other exotic, but equally serious, diseases such as African Horse Sickness so any knowledge and understanding of the midges' ...

Tips from the Journals of the American Society for Microbiology

... K. Block, J. Woraratanadharm, L. Chen, C. Hayes, J.Y. Dong, K. Porter. 2008. A tetravalent dengue virus vaccine based on a complex adenovirus vector provides significant protection in rhesus monkeys against all four serotypes of dengue virus. Journal of Virology , 82. 14: 6927-6934.) ...

UCLA researchers locate and image prostate cancer as it spreads to lymph nodes

... is killing the cancer. Using mouse models, Wu and her team engineered a virus to travel to the lymph nodes, using a prostate cancer-specific vector that dictates s its protein payload be expressed only in prostate cells. The payload in this case is a protein that can be imaged by PET scanning. ...

From foe to friend: Researchers use salmonella as a way to administer vaccines in the body

... and other food crops. Curtiss' team, through genetic know-how, has developed a variety of ways to tame salmonella in the lab and use it as a delivery vector for vaccines. "We try to genetically modify the salmonella bacterium to eliminate its harmful effects -- the diarrhea, gut inflammation and fluid ...

Diversity among bird populations found to reduce threat of West Nile virus

... virus infection in the human population. West Nile develops rapidly in bird populations, and then can be passed to humans or other animals through a vector mechanism, often a mosquito. Swaddle completed the work while a Sabbatical Fellow at the National Center for Ecological Analysis and Synthesis ...

New paradigm for cell-specific gene delivery

... diseases of the vasculature. It can be highly cell-specific, mimic or restore normal in vivo function, and can be permanent or transient depending on vector design. Currently, a number of gene delivery systems for use on the arterial wall are being studied, but as yet their low efficiency in gene ...

UC Davis stem researchers demonstrate safety of gene therapy using adult stem cells

... mesenchymal stem cells. Of the mice used in the long-term study, four developed human leukemia. None of those mice, however, were found to have vector DNA present in the malignant cells. "This is evidence of a natural tendency for human bone marrow stem cells to develop leukemia in long-term ...

New vaccine may give long-term defense against deadly bird flu and its variant forms

... from two types of the H5N1 avian influenza. The adenovirus is incapable of multiplying and so cannot cause illness to people. By using the adenovirus vector technology, a couple of problems with existing vaccines used to fight annual flu outbreaks are solved. Problems with current influenza vaccines ...