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valves in Biological News

Heart valves that grow with the patient

... of tissue engineered biological cardiac valves for children , which grow with the patients an ... are performed on children. The mechanical heart valves normally used in these operations have the ... susceptible to infections. The biological heart valves from pigs or cows used as an alternative are ...

NIH awards Clemson bioengineer $1.5 million to improve durability of tissue heart valves

... four years to develop durable bioprosthetic heart valves (BHVs). Aortic valves taken from pigs are used in thousands of human ... in durability will allow surgeons to implant the valves in the younger patient population. Vyavahare ...

Prosthetic vein valve designed to direct blood flow shows promising pre-clinical results

... people in the United States alone, occurs when valves in a person's veins can no longer ensure a ... toes because of gravity, but the body uses vein valves to pump blood in one direction back to the ... symptoms rather than the cause. Damaged vein valves can sometimes be repaired, but when that isn't ...

Skewered pumpkins

... is available in German . We encounter valves every day, whether in the water faucet, the carburetor in our car, or our bicycle tire tube. valves are also present in the world of nanotechnology. ... the pumpkins come off, opening the pores. Now the valves are open and the guest molecules can exit. At ...

Endobronchial valve significantly improves emphysema

... at the University of Pittsburgh. Endobronchial valves can allow these over-distended, diseased portions ... the lobes of the lung and whose endobronchial valves were placed to exclude the entire diseased lobe ... patients required implantation of three to five valves to isolate the most damaged sections of their ...

A step toward tissue-engineered heart structures for children

... have now developed a solution: living, growing valves created in the lab from a patients own cells. ... September 11, they describe making pulmonary valves through tissue engineering. These valves, which ... labs in the U.S. thats attempting to make heart valves through tissue engineering. We hope these could ...

Music is the engine of new U-M lab-on-a-chip device

... in a microfluidic device today, researchers often use dozens of air hoses, valves and electrical connections between the chip and a computer to move, mix ... student Sean Langelier, and their collaborators replaces these air hoses, valves and electrical connections with what are called resonance cavities. The ...

From cars to cancer: UH professor employs auto industry tools for tumor therapy

... directly to the printer," he said. Back in Michigan, Kamrani prototyped valves and cylinders. Today, he's prototyping bones and organs. "The concept ... problem: trying to create a three-dimensional geometry, going from valves to skulls and things like that." Dong called Kamrani's idea of ...

Old growth giants limited by water-pulling ability

... to get errant air bubbles to enter. "Higher and higher in the tree, the valves are able to withstand more pulling force from the long heavy column of ... can be sucked through," Lachenbruch said. "But the problem is that the valves become less efficient at letting water pass. The height at which no water ...

'Healthy' sterols may pose health risk

... these compounds do have their own risks, as they can accumulate in heart valves and lead to stenosis. Aortic valve stenosis (AS) results from ... They collected blood samples from 82 patients with severe AS and aortic valves from 21 individuals undergoing valve surgery, along with respective ...

Improved foam for varicose veins found to be safe in preliminary results from phase II trial

... at Wake Forest University Baptist Medical Center. Veins in the leg have valves that are designed to prevent blood from flowing backward as it returns to the heart. Varicose veins are caused by weakened valves (commonly in the great saphenous vein, the large vein running up the inner ...

Test helps in fight against lung infections and for treating other life-threatening infections

... bioFILM PA™ that will address biofilm infections caused by other bacteria such as infections of catheters, artificial joints, mechanical heart valves and other devices. Innovotech™ Inc. developed bioFILM PA™ and the University of Alberta Hospital laboratory, under the direction of ...

Researchers achieve major breakthrough with water desalination system

... this project. "It can control a variety of process variables, including the precise measure of chemical additives to condition the water. All the valves are computer-controlled, so the system can adjust itself automatically. We can also see how much energy we're using, and in the software, we've also ...

Protein that triggers plant cell division revealed by researchers

... From the valves in a human heart to the quills on a porcupine to the petals on a summer lily, the living world is as varied as it is vast. For this to be possible, ...

Engineered pig stem cells bridge the mouse-human gap

... biology to humans, as evidenced by their already extensive contributions to medicine, such as using pig insulin to treat diabetes or pig heart valves in transplant surgery. The research group modified the current iPS protocols to successfully generate a line of stem cells from a miniature Tibetan ...

'Beating' heart machine expedites research and development of new surgical tools, techniques

... animal or clinical trials. Currently, most medical device prototypes designed for use in heart surgery are tested on live pigs, which have heart valves that are anatomically similar to human heart valves. However, these tests are both expensive and time-consuming, and involve a lengthy permission ...

Building the lymphatic drainage system

... published online April 27 ( www.jcb.org ) and will appear in the May 4 print issue of the Journal of Cell Biology . Foxc2 built the lymph vessel valves with the help of NFATc1, which was a known heart valve engineer. Norrmn and colleagues also showed that Foxc2 and NFATc1 physically interact and that ...

Researchers advance knowledge of little 'nano-machines' in our body

... of ions between the cells and their environment, which allows the transmission of electrical signals along our nerve cells. The size of these small valves is about a million times smaller than the pupil of a human eye. The new technique will allow scientist to measure one single ion channel at the time ...

Nanoscale coating protect products -- and the economy

... can prevent that from happening." They do it by adjusting to conditions within the human body that can cause hairline cracks to form in heart valves or holes in artificial joints, for example, preventing implant rejection or failure. Relying on 'Dorothy' Achieving the right characteristics ...

Pivotal national trial uses newest interventional radiology treatment to bust blood clots in legs

... do not dissolve the existing clot, which remains in the leg. While many patients' clots will slowly dissolve over time, often the vein wall and vein valves become irreversibly damaged in the process. "PTS develops as a direct result of having the blood clot stay in the vein. The blood clot continues to ...

New step forward in search for solution to infection puzzle

... and could help the future development of new treatments for rare but serious conditions such as infective endocarditis, an infection of the lining or valves of the heart." ...

Turning on cell-cell communication wipes out staph biofilms

... chronic biofilm infections. "Current treatment for endocarditis -- a potentially life threatening infection where a staph biofilm forms on heart valves -- involves weeks of intravenous antibiotics, and sometimes requires surgery," Boles explained. "One thing we'd like to test is whether we can treat ...

Cardiologists and heart surgeons meet for 'Controversies and Advances' conference

... medical procedures have done nothing to reduce the friction. The ongoing debate as to whether it is better to replace and repair aortic and mitral valves surgically or to manage them medically is just one example. And when considering treatment options for Atrial Fibrillation, the choices are even more ...

Minimally invasive heart surgery research wins NIH award

... instrument through the chambers of the heart to the surgical site and deploy an array of tools from its tip to remove blockages, repair faulty valves and close leaks inside the beating heart. The repair of complex heart defects through open heart surgery has become routine, in great part ...

Emerging (disease) markets

... suppliers and vendors Ending trade that is unsustainable. Preventing the spread of the next potential pandemic could depend on closing the valves through which pathogens currently flow, said Martin Gilbert, a WCS veterinarian currently studying diseases in wildlife markets in Asia. There is a ...

Magnetic computer sensors may help study biomolecules

... access memory (MRAM) for biosciences. Spin valves are made by stacking thin layers of materials ... silicon nitride membrane in fluid. When the spin valves are turned on, a local magnetic field is created ... The NIST experiments demonstrated that the spin valves not only can trap magnetic particles, but also ...

Bone and cartilage growth to blame for heart valve disease

... Medicine, who examined diseased mitral and aortic valves removed during surgery for the study. "Common ... has always been that thickening of the mitral valves was part of the aging process as deposits of ... human studies. "I wanted to know why diseased valves had were hardened with a glassy whitish ...

Why Christmas trees are not extinct

... only survive but thrive: efficient microscopic valves let water flow through conifers about as easily ... says that if conifers had not evolved easy-flow valves to make up for the short length of their water ... an evergreen must pass through 10 times as many valves (known technically as "pits") as water moving up ...

Engineering the heart piece by piece

... areas that died during their attack. Children born with defective heart valves might get new ones that can grow in place, rather than being replaced ... than ever to “bioengineering?entire areas of the heart, as well as heart valves and major blood vessels. But hurdles still remain before the ...

Development of portable infectious disease detector

... a reality. However, putting microscopic arrays of channels, pumps and valves to move around minute amounts of liquid on silicon chips proved to be ... of cells, they have adapted a method for molding micro-channels and valves into a material similar to that used in soft contact lenses. This has ...

Percutaneous aortic valve replacement safe, successful in high-risk patients

... Catheter techniques are expanding into new territory, successfully aiding in the replacement of narrowed, calcified aortic valves in patients too sick to withstand open-chest surgery. According to a study reported at the 30th Annual Scientific Sessions of the Society for ...

Natural polyester makes new sutures stronger, safer

... surgical meshes, multifilament fibers and stents. Ultimately, the researchers hope to develop an artificial scaffold that could be used to grow heart valves after being implanted in a patient, which would spare children with heart valve defects from undergoing repeated surgeries. Tests of the device in ...

Microfluidic chip helps solve cellular mating puzzle

... channels and chambers, some 20 times smaller than the diameter of human hair. Within the chip, computer-controlled fluid pressure and microscopic valves allow the researchers to isolate and conduct experiments on extremely small clusters of cells. "The level of control we can achieve on the conditions ...

Researchers show that veins stiffen as we age

... Microscopic capillaries connect the arteries to the veins. The veins then transport the blood back to the heart. The veins are equipped with valves to prevent any backflow of blood caused by gravity as blood is returned to the heart from the lower extremities. The walls of the veins are made of ...

How blood flow dictates gene expression

... embryo mirrors events in previous tissue-culture studies. They found that Klf2 is expressed on the high-flow side of developing mitral and aortic valves in the heart of a 14-day-old embryo. The researchers surmise that the mechanical stimulus of blood flowing in a vessel leads to the upregulation ...

Study shows pine bark naturally decreases severe chronic venous insufficiency

... pools in their leg veins, legs and ankles can become swollen," said Peter Rohdewald, Ph.D. and researcher of the study. "Eventually, some of the valves cannot hold the weight of excessive blood, which then adds more pressure onto the next valve further downwards. Ultimately, the inability to prevent ...

Researchers develop portable 'vein finder' for faster, more accurate injections

... ones, providing critical 3-D information about a vein's location. Hospitals have sophisticated ultrasound systems to evaluate the heart, valves and vessels for general blood-flow studies. But this kind of equipment is impractical and too costly for field use. "Although the use of Doppler ...

Stem cells' electric abilities might help their safe clinical use

... of medicine at The Johns Hopkins University School of Medicine and senior author of the study. "Our discovery of functional ion channels, which are valves in a cell's outer membrane allowing the passage of charged atoms, the basis of electricity, provides an important link to the differentiation, or ...

UCSD team discovers specialized, rare heart stem cells in newborns

... pediatric cardiologists and cardiac surgeons have relied on mechanical devices, human and synthetic tissue grafts, and artificial and animal derived valves to surgically repair heart defects. While progenitor cells won't grow a whole new heart, our research has shown that they can spontaneously become ...
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