New study reveals the protein that makes phosphate chains in yeast
... of polyphosphates. Vtc4p is part of a protein complex called vacuolar transporter chaperone complex (VTC) that is usually found in the membranes of vacuoles pouches in which cells store molecules for later use, transport or destruction. "This protein is like a factory," says Klaus Scheffzek, whose ...Tips from the Journals of the American Society for Microbiology
... S. enterica, and Listeria monocytogenes. They were then monitored for their ability to sequester the bacteria and for vesicle production (food vacuoles released by protozoa offering a means of protection to some bacteria). Results showed Glaucoma produced vesicles with all bacterial strains and ...RING finger protein 5 may guide treatment for muscle disease in older adults
... to what is often seen in patients with IBM, muscle specimens from RNF5 overexpressing animals revealed the presence of structures known as rimmed vacuoles and congophilic inclusions, hallmarks of this disease. The researchers also found increased levels of markers characteristic of ER stress, a ...Cornell researcher seeks clues to how tuberculosis infects cells
... College of Veterinary Medicine, and colleagues reported in a November issue of the journal Cell Host and Microbe, that increased acidity inside the vacuoles containing the bacteria serves as the trigger for M. tuberculosis genes to express proteins. The study also compared the responses of M. ...Legionnaire's bacterial proteins work together to survive
... that are part of the immune system and eat cellular debris and toxins. Macrophages kill bacteria by transporting them in storage bubbles known as vacuoles to organelles that have enzymes to then break down the intruders. What makes this pathogen special is that it can control transport of the ...The biggest bug in gut discomfort
... of intracellular hideouts. These C. jejuni-filled vacuoles make their own way toward the nucleus, taking up ... yet surprisingly the dyes were unable to enter vacuoles containing C. jejuni. The bug had left the ... pathway early and that the segregated C. jejuni vacuoles move to a perinuclear location where they become ...Researchers discover how malaria parasite disperses from red blood cells
... the red blood cells and the merozoite-containing vacuoles inside them swelled and then burst like a balloon ... Another theory held that the merozoite-containing vacuoles would fuse with the cell membrane, and then ... theory also offered an inaccurate picture, as the vacuoles ruptured at roughly the same time as the cell ...New egg freezing technique offers hope to hundreds of women
... normal when observed with LM, although some eggs showed the development of vacuoles (small cavities that sometimes contain water, food or metabolic waste) in ... those treated with EG and with the PrOH agent containing more sucrose, had vacuoles developing ?a process known as vacuolisation. Professor Nottola said: ...Anti-wrinkle compound causes pathological reaction in skin cells
... In vitro tests conducted by Dr. Marceau’s team revealed that the application of DMAE induces a quick and spectacular swelling of skin cell vacuoles called fibroblasts, which act as reservoirs and interface between the inside and the outside of the cell. In the hours following the application ...Targeted virus compels cancer cells to eat themselves
... no detectable brain tumors. Analyses of dead cancer cells showed telltale signs of autophagy: bits of virus in the cell nucleus and autophagic vacuoles -- cavities with residual digested material. The cells showed no sign of having been killed by apoptosis -- a much better known process of ...