transposon

Scientists identify genes responsible for 'black rot' disease in vegetables

...athogenicity, the researchers then screened an Xcc transposon insertional mutant library in its host plant (cabbage). They screened a total of 16,512 Xcc mutants on individual cabbage plants and, of these, 172 proved to be non-pathogenic. Upon further characterization of the 172 non-pathogenic mutants, the rese...

Sleeping beauty plays a significant role in identifying cancer genes

...tigated the use of a highly mobile Sleeping Beauty transposon system to study lymphomas, a cancer that strikes t...esis using a highly mobile somatic Sleeping Beauty transposon system," Nature, Vol. 436, No. 7047. ...

New technique could alter field of mouse genetics

...ity in Shanghai, China, began their studies with a transposon called piggyBac. With the help of a partner enzyme...rks, day in and day out. It's fairly rare to get a transposon that works on a large scale in an effective way. This looks very promising." Transposons have been ...

Ancient DNA helps UF researchers unearth potential hemophilia therapy

... strand of DNA present in modern-day fish called a transposon to transport the gene directly into the DNA of the...llowing them to chauffeur genes into the cell. The transposon UF researchers used is one of a few that work in mammals, but until University of Minnesota scientis...

Jumping gene could provide non-viral alternative for gene therapy

... from radiation therapy. They found the piggyBac transposon was five to 10 times better than the other circula...o add a therapeutic gene, we can put it within the transposon and use it to deliver the gene into the cell," says Dr. Joseph M. Kaminski, radiation oncologist at ...