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tolerance in Biological News

REGiMMUNE presents enhanced efficacy data in preclinical transplantation models

... demonstrated enhanced efficacy in transplantation tolerance induction in models of skin transplantation and ... today in a poster titled "Donor-Specific tolerance Induction by a Liposomal Formulation of KRN7000 ... in combination with Sirolimus in transplantation tolerance induction in mouse models. Study Results ...

A little java makes it easier to jive, researcher says

... Motl said, "is that when we found that caffeine tolerance doesn't matter, we were perplexed at first. Then ... of the literature relative to caffeine and tolerance effects across a variety of other stimuli. ... have that bigger, mental-energy effect. But the tolerance effect is not ubiquitous across all stimuli. Even ...

Bayhill Therapeutics and the Juvenile Diabetes Research Foundation announce research collaboration

... to evaluate safety, pharmacodynamics, immune tolerance and pancreatic function in patients with T1D. ... preservation as well as the induction of immune tolerance to pancreatic autoantigens. Clinical Trial ... C-peptide increase during screening mixed meal tolerance test, and presence of antibodies to at least one ...

MicroRNA implicated as molecular factor in alcohol tolerance

... noted NIAAA Director Ting-Kai Li, MD. tolerance is the decrease in sensitivity to alcohol that ... alcohol over time. Individuals who develop high tolerance (low sensitivity) to alcohol are at increased ... structure known as the BK channel develops tolerance to alcohol, particularly in the supraoptic ...

Drought tolerance in potatoes

... the genes and molecular mechanisms of drought tolerance in order to engineer new drought-resistant crops ... Bonierbale, are examining the genes for drought tolerance traits in several native Andean potato landraces. ... these genes contribute to the increased drought tolerance of the two clones under investigation. ...

Gates funding to help poor rice farmers

... have been confounded by the challenges of stress tolerance for decades, said Dr. Zeigler. But the ... itcan benefit from new varieties with sufficient tolerance of submergence, salinity, and stagnant flooding. ... of Japan (499.5 million$4.7 millionfor flood tolerance in Southeast Asia), Germanys Federal Ministry for ...

Relevance of rice research recognized

... factor-like gene that confers submergence tolerance to rice, appeared in the 10 August 2006 issue of ... of a gene (Sub1A) that confers submergence tolerance to rice, and the consequent breeding of this gene ... A time-lapse video, which compares the flood tolerance capabilities of the popular IR64 rice variety ...

UCR researchers awarded nearly $1.7M to develop improved cowpea varieties

... new and improved cowpea cultivars that have tolerance to drought as well as improved resistance to ... identify genes linked to important traits such as tolerance to drought and resistance to pests. The grant ... varieties have combinations of heat and drought tolerance and improved pest resistance that enhance farmer ...

CU researcher engineers sorghum that grows in poisonous soils

... species as wheat and maize can boost aluminum tolerance in crops. Sorghum is an important food crop in ... the physiological mechanisms of plant aluminum tolerance as well as its molecular basis," said Leon ... for further exploring the mechanisms of aluminum tolerance and discovering new molecular genetic solutions ...

Hunt for 'climate-ready' crops accelerates as organizations search seed collections worldwide

... pathogen responsible for bacterial wilt; a search for novel traits with tolerance to heat and drought stresses in Chilean maize crop collections; a project ... advances in improving nutritional quality in maize, by adding in drought tolerance so that new varieties can benefit the most vulnerable growers in marginal ...

Ben-Gurion University of the Negev signs collaborative contract with Bayer CropScience

... in detail and the team found that by removing either of the two genes, the tolerance of the model plant, Arabidopsis, to heat, salt and drought could be ... estimated 30,000 Arabidopsis genes to identify additional candidate stress tolerance genes. Ben-Gurion University of the Negev was created to spearhead the ...

Science returns to the Capitol Hill spotlight at March 24 exhibition

... pathogen outbreaks in agricultural systems, improving drought tolerance in plants Science Policy: the science of science and innovation ... University American Society of Plant Biologists, Improving Drought tolerance in Plants, Sarah M. Assmann, Pennsylvania State University American ...

Evolutionary process more detailed than previously believed, study shows

... as scientists work to enhance microorganisms so that they possess a higher tolerance to the products they produce, Kao said. For example, a microorganism ... however, Kao explained, is these microorganisms generally have a low tolerance to butanol, and at very low concentrations they will start to die from ...

UC Riverside rice geneticist receives high honor from US Department of Agriculture

... have focused in particular on Sub1A, a gene responsible for flood tolerance and found only in some low-yielding rice varieties in India and Sri Lanka. ... "Dave Mackill recognized rice plants with exceptional submergence tolerance and sought the rice chromosome and region that carried the trait. Pamela ...

Growing fuel and medicine: Advancing biofuels and plant-produced therapeutics

... MI pathway to AsA. One of our current objectives is to study the stress tolerance and growth of these high AsA lines. MIOX4 and GLOase over-expressers were ... of both aerial and underground tissues. In addition, these lines exhibited tolerance to common environmental pollutants such as trichloroethylene, a ...

Risk and reward compete in brain

... analysis and planning. By giving volunteers a task that measures risk tolerance and observing their reactions with functional magnetic resonance imaging ... In his previous research, Bechara had used the same task to measure risk tolerance in brain-damaged patients. He and other researchers showed that the ...

AgriLife Research breeder develops drought-tolerant corn

... ETTER At the end of the day, drought tolerance in corn has to equate to good yields and good quality, not just good ... Spinhirne said. "Developing and using new corn hybrids with improved tolerance to drought and other stresses is important and a viable water-saving ...

Why juniper trees can live on less water

... species growing in wet parts of the Caribbean also benefit from drought tolerance because they "tend to grow in shallow, rocky soils that don't hold a lot ... how and where these tree types evolved their collective drought tolerance by analyzing each juniper species' DNA. That analysis found that junipers ...

UVa Health System team uncovers gene's role in type 1 diabetes

... the 12/15-LO gene and remained non-diabetic demonstrated better glucose tolerance than non-diabetic NOD mice that were matched for age. (Worse glucose tolerance is an indication of having a pre-diabetes condition). The same group of ...

New crops needed for new climate

... of sufficient quantities of protein. Data have also shown that cassava, a staple food crop in tropical and subtropical regions due to its tolerance of arid conditions, may experience yield reductions in high CO 2 . Combined with an increase in cyanogenic glycosides, this has major implications ...

Scientists closer to developing salt-tolerant crops

... the transpiration stream before it gets to the shoot. "This reduces the amount of toxic Na+ building up in the shoot and so increases the plant's tolerance to salinity," Professor Tester says. "In doing this, we've enhanced a process used naturally by plants to minimize the movement of Na+ to the ...

New national genome center launched

... can then be used for developments that include the production of new antibiotics to fight 'superbugs', breeding of new crops with increased tolerance of drought, and the breeding of livestock better able to resist emerging exotic disease. TGAC will underpin these advances as well as making a ...

Evolution: Crabs go deep to avoid hot water

... life in the deep sea. The process of adaptation to constant low temperatures (1-4C) prevailing in the deep sea seems to have narrowed the temperature tolerance range of the crabs where they have emerged to the surface waters in the Southern Hemisphere. With differences of only a couple of degrees in ...

Single thawed embryo transfer after PGD does not affect pregnancy rates

... concerns about how well biopsied embryos survive after freezing and thawing. "It was thought that the effect of the biopsy might reduce the embryos' tolerance to freezing. This concern was not based on any scientific evidence, only on observations of low survival rates of biopsied frozen embryos," said Dr ...

New crops needed for new climate

... of sufficient quantities of protein. Data have also shown that cassava, a staple food crop in tropical and subtropical regions due to its tolerance of arid conditions, may experience yield reductions in high CO 2 . Combined with an increase in cyanogenic glycosides, this has major implications ...

T-STAR grant funds genetic studies on shrimp and papaya and endangered cycad rescue

... $162,856 in collaboration with Dr. D. Nandwani from the Northern Marianas College to improve papaya cultivars from the Mariana Islands in their tolerance to papaya ringspot virus (PRV) and other important diseases. Dr. Wall's studies have found that a local variety is tolerant to PRV but needs genetic ...

American Society for Microbiology honors George Liu

... on microbial pathogenesis and novel antibacterial therapies. His early successful graduate work was the investigation of the mechanism of immunologic tolerance in a model of autoimmunity. His novel concept that the low affinity of certain autoantigenic peptides could provide a basis for the existence ...

Next-generation software system for flood warning and risk analysis to be developed

... herald in a new wave of extreme floods, we are beginning to see emphasis on effective flood forecasting with quantifiable uncertainties and minimum tolerance for error. NEWS comes at the right time for the good of citizens in China and the UK." Potential end-users include insurance companies (using ...

Synthetic chemical offers solution for crops facing drought

... Sciences at the University of California, Riverside, suggests the possibility of spraying stable synthetic chemicals on plants to enhance stress tolerance during times of drought and improve yield. Using a method called chemical genomics, pioneered by UC Riverside researchers for studying plant ...

Genome projects launched for three extreme-environment animals

... undergone millions of years of evolution that has not involved species migration or artificial selection. It has several adaptations for alpine-cold tolerance and most specifically for anti-hypoxia and running, making it a key model animal to investigate mammalian hypoxia adaptability. The launch of ...

Animals that seem identical may be completely different species

... of environmental toxins. "Different species have different characteristics. If it emerged that these two species differ in terms of their tolerance towards certain toxins, then it could be difficult to make comparisons between different studies," says Christer Ersus. And as this advanced DNA ...

LSUHSC student awarded top national honor for diabetes research

... on Tuesday, April 21, 2009 at 9:00 a.m. in Room 242 at the Ernest N. Morial Convention Center. The research team previously demonstrated that glucose tolerance and fasting blood glucose levels in diabetic mice were improved when the pancreas overproduced Angiotensin-converting enzyme (ACE) 2. They ...

2009 ASPB Summer Undergraduate Research Fellowship award announcement

... ASPB very much for this opportunity. Sharon Holifield, University of Arkansas Mentor: Ken Korth The role of glyoxalase I in abiotic stress tolerance of soybean, Glycine max. I am more than excited about being able to do this summer research project. This is an excellent opportunity for me to get ...

Saving energy and the environment with Flywheels

... generatormeeting emergency power regulations that stipulate gensets must be able to assume the load within 10 seconds. Flywheels also have a higher tolerance for rapid cycling. "I am very pleased with the fuel and emissions savings results we are seeing and with additional improvements currently under ...

UC Davis bench-to-bedside research: Promising treatment in clinical trials

... study designed to establish proof of concept that s-EH inhibition modulates glucose metabolism or blood pressure in patients with impaired glucose tolerance and hypertension." ."AR9281 has demonstrated an excellent safety profile and activity in multiple animal models of type 2 diabetes, and has the ...

Highlights from the March editions of ESA journals

... the future spread of invasive species presents a challenge to ecologists that has until recently only been addressed by comparing species climate tolerance with established climate maps to predict susceptible areas. A new study finds, however, that when land-use and habitat data are incorporated, models ...

Scientists to sequence DNA of British wheat varieties

... work together, will allow us to identify variation in gene networks involved in important agricultural traits such as disease resistance, drought tolerance and yield. The tools generated will allow us to apply our knowledge of natural variations in the genome to traditional crop breeding." ...

Genome of a heat and drought resistant cereal plant analyzed

... one of our most important research topics. That is why we are trying to learn something about the molecular basis of the plant's pronounced drought tolerance in order to apply this knowledge to other crop plants in our latitude zone as well. "The first results of the study have been published in the ...

Genome sequence shows sorghum's immense potential

... a quarter the size of the human genome. The results of the study appear in the Jan. 29 issue of international science journal Nature . Drought tolerance makes sorghum important in dry regions like northeast Africa and the U.S. southern plains. It needs only half the water it takes to grow corn. ...

Implants mimic infection to rally immune system against tumors

... to other situations in which it is desirable to promote a destructive immune response (for example, eradicate infectious diseases) or to promote tolerance (for example, subvert autoimmune disease)." ...
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