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tag in Biological News

TRAPping proteins that work together inside living cells

... and her colleagues build a tiny molecule called a tag into the initial protein. They then add a small ... to the living cell, which finds and fits into the tag like two pieces in a puzzle. TRAP waves around, ... RNA polymerase complex. The team engineered a tag in the C-terminus and cultured bacteria with the ...

Sugarcoating fruit fly development

... they report that the addition of this sugar tag to proteins in the nucleus of a cell is vital for ... called Polyhomeotic, is modified with the sugar tag by Ogt and might be the link between Ogt and ... are necessary to find out how the sugar tag affects the function of Polyhomeotic. "Our ...

New tracking tags are providing fish-eye views of ways to manage depressed fisheries

... despite strict quotas. A project known as tag A Giant (TAG) uses an implanted tag in the tuna to record external pressure, internal ... tuna must be recaptured to recover these data. tag also uses a ...

Major step for drug discovery and diagnostics

... have developed a system, where they tie a tag to the protein that attach it to a surface and ... function. Swimsuits for proteins with a tag With our new method we can study membrane ... while keeping its function intact. We attach a tag to the amphipol that will assemble to a surface ...

Tailor-made recombinant proteins in mammals

... scaled up." Enter Bertozzi's aldehyde tag: the tag is an aldehyde group displayed as part of an ... normally make up a protein. When the aldehyde tag appears at a specific site on a given protein, a ... Bertozzi's group proved they could precisely tag the Fc fragment of the IgG molecule so that it ...

1,000 tags reveal mysteries of giant bluefin tuna

... being fitted with the 1000th electronic tracking tag placed on this threatened species when it was ... and Steve Wilson of Stanford University. The tag team has been tagging bluefin tuna since 1996, when the first tag was put out on a bluefin tuna off North ...

New technology illuminates protein interactions in living cells

... Conn. While fluorescence has long been used to tag biological molecules, a new technology developed ... when they bind to a specific amino acid tag sequence within a protein. While these compounds ... researchers strategy was to split the amino acid tag for the dye into two pieces, locating each piece ...

Hydrothermal vents: Hot spots of microbial diversity

... Using a new analytical technique called 454 tag sequencing, the scientists surveyed one million ... with microbial population structures using 454 tag sequencing allows scientists to assess how ... populations and diversity. The MBLs 454 tag sequencing strategy is an important contribution ...

Yale researchers uncover secrets of salmonella's stealth attack

... found that Salmonella coaxes the cell to "mark" the SopB protein with a tag called ubiquitin. Addition of this tag makes the bacterial protein recognizable to the cellular machinery that ...

UNH researchers track lobster migrations to improve population estimates

... movements. Commercial lobstermen are assisting Goldstein by helping to tag some of the creatures they find in their traps. In many cases, lobstermen who capture tagged lobsters will call Goldstein to report the tag number and location. In addition, 15 "lobster listening stations" ...

UBC researcher reveals humpback whales' dining habits -- and costs

... whales off the coast of California using a non-invasive, temporary digital tag that records depth, body angle and other acoustic data. After multiple ... for its energy expenditure, according to the study. By integrating tag data and hydrodynamic theory inspired from parachute inflation studies, ...

InvoTech Selects M2SYS Technology for Leading-Edge Fingerprint Software Solution

... its customers with the ability to utilize barcodes, RFID, and touch tag technology to track important employee activities within its SAMS(TM) ... security department responsibilities and utilizes barcode, RFID, and touch tag technology to facilitate and validate pertinent activities. *(LOGO ...

UNH researchers tag first-ever free-swimming leatherback turtles in New England

... have been spotted. This off-shore access allowed Dodge to put a tag on a male; because they never return to shore after they hatch, little is ... effort will continue off Cape Cod through September; Dodge hopes to tag nine more leatherbacks. In addition to the National Fish and Wildlife ...

UI and ISU establish shared DNA sequencing instrumentation

... The Iowa State sequencer is an Illumina Genome Analyzer II with a price tag of more than $535,000. The instrument will be part of the DNA Facility of ... crop traits in plants. It includes ChIP-seq, digital gene expression tag profiling, whole genome and candidate gene re-sequencing, and small RNA ...

Leatherback turtles' newly discovered migration route may be roadmap to salvation

... to intervene on their behalf is hugely challenging. But a major effort to tag and track leatherbacks that nest on the Pacific coast of Costa Rica has ... the coast of Central America, where it stayed for the entire time the tag was working, 588 days. "It seems logical that turtles would want to ...

Genetic 'tag team' keeps cells on cycle

... new evidence that a network of influential genes act as a kind of genetic tag team to orchestrate one of the most fundamental aspects of all life: the ... themselves are among the genes targeted by this transcription-activating tag team. Those cyclins are also known to influence the behavior of the ...

To save or savor? It's decision time for Atlantic bluefin tuna

... needed to bring the Gulf of Mexico bluefin population back. The tag team's research has shown that bluefin tuna tagged in the West Atlantic ... that are virtually impossible to identify without a genetic approach or a tag track that spans years," Block said. "I believe that stock ...

Botched production of insulin molecule may lead to diabetes

... and folding of the proinsulin molecule deep within the beta cell. Using a tag that can make proinsulin glow green, they have now found a way to watch ... First, the team engineered the gene for human proinsulin to insert a tag that makes the protein fluorescent, but does not interfere with the ...

Researchers capture bacterial infection on film

... into the embryos and observing their interaction with the insect's immune system using time-lapse confocal microscopy. The researchers can also tag individual bacterial proteins to follow their movement and determine their specific roles in the infection process. The scientists are hoping to ...

Technology improves salmon passage at hydropower dams

... PNNL and the U.S. Army Corps of Engineers' Portland District. The information was gathered by surgically implanting 4,140 young salmon with a tag that's part of the Juvenile Salmon Acoustic Telemetry System (JSATS). The JSATS-tagged fish were released from the Lower Granite Dam on the Snake ...

Scientists are learning more about big birds from feathers

... a risk to their would-be captors. Instead of catching eagles, DeWoody collects their feathers and uses the small amount of DNA in them to create a tag that corresponds to a particular bird. Those tags can be used to determine population, parentage, roosting patterns and sex ratio. "In an ...

Protein that triggers plant cell division revealed by researchers

... divisions, even though BASL's structure doesn't look like any of them. Bergmann, Dong, and MacAlister tracked BASL by adding a fluorescent tag that could be monitored under the microscope. This way, they could watch BASL as cells divided. They found that BASL behaved in some ways like ...

P[acman]-generated fruit fly gene 'library': A new research tool

... a gene and rescue a mutation, or do a structure/function analysis of the gene," Bellen said. "If you don't know where the gene is expressed, you can tag it, put it back and locate where it is expressed." The library is available at http://pacmanfly.org/ . ...

Genetic secrets of date palm unlocked by researchers at Weill Cornell Medical College in Qatar

... the WCMC-Q researchers used a next-generation sequencing approach, which Mr. Malek says offers data quality between that of the expressed sequence tag (EST) method and the traditional whole-genome mapping method. "We were able to develop a relatively unbiased view of the gene space of the entire ...

Ultrasound imaging now possible with a smartphone

... A typical, portable ultrasound device may cost as much as $30,000. Some of these USB-based probes sell for less than $2,000 with the goal of a price tag as low as $500. Another promising application is for caregivers of patients with Duchene's Muscular Dystrophy. A degenerative disease that often ...

Penn researchers demonstrate a new model for drug discovery with a fluorescent anesthetic

... after testing it successfully in tadpoles. By using transparent, albino tadpoles in the study, researchers were able to follow the fluorophore tag and image it in the brain of the immobilized, living animal. Because the compound is fluorescent, researchers are able to image the compound in ...

New high-throughput screening technique makes probing puzzling proteins possible

... causing their emitted light to be less polarized, so light from larger molecules is measurably more polarized. The fluorescent probes used to tag proteins are typically quite small, so their fluorescence is not very polarized. But, when a probe attaches to a protein, together they make a much ...

Tall tale of giant stingray circles the globe

... to extinction by the International Union for Conservation of Nature (IUCN). If he can get more funding for the project, Hogan hopes to eventually tag 40-50 stingrays for the research study, the first ever ecological study of the giant freshwater stingray which was discovered only 20 years ago. ...

CSHL researchers pinpoint structure-building role for 2 non-coding RNAs

... reveal the molecules they interact with and the pathways they participate in," explains Spector. Using a technique that uses a fluorescence signal to tag molecules within cells, Spector's team traced two of their 14 ncRNAs to paraspeckles, tiny compartments that look like dense dots anchored within the ...

Fowl soil additive breaks down crude oil

... soil often involves the use of expensive fertilizers containing nitrogen and phosphorus, and again may come with an additional environmental price tag despite the bio label. Soil hardening and a loss of soil quality often accompany this approach. Ma and colleagues suggest that animal waste, and ...

A worm-and-mouse tale: B cells deserve more respect

... they become a serious risk to our health. For many years, scientists believed that the major job of B cells was to identify foreign invaders and tag them with antibodies, marking the microbe for destruction by the immune system. But scientists are discovering that B cells do much more, resulting ...

Animal trackers collaborate on new Google Earth for oceans

... location at the same time. Its an important evolution in being able to "see" the largest portion of our planet." The ability to simultaneously tag and track large numbers of open ocean animals, representing a variety of different species, has been pioneered over more than a decade by Block and ...

Human genomics in China

... were made in the development of technologies for human genome genotyping and genetic polymorphism detection, as well as for expressed sequence tag (EST) and full-length cDNA cloning and sequencing. All these achievements greatly strengthened the Chinese scientists' confidence and encouraged ...

Marine invasive species advance 50 km per decade, World Conference on Marine Biodiversity told

... over the past decades, Pauly says it is more common than assumed. Rudolf de Groot, of Wageningen Univeristy, the Netherlands, puts a price tag on the beneftis derived from the protection of coastal ecosystem. He has calculated that effective protection of 20-30% of coastal ecosystems costs ...

Marine invasive species advance 50km per decade, World Conference on Marine Biodiversity told

... over the past decades, Pauly says it is more common than assumed. Rudolf de Groot, of Wageningen Univeristy, the Netherlands, puts a price tag on the beneftis derived from the protection of coastal ecosystem. He has calculated that effective protection of 20-30% of coastal ecosystems costs ...

Salmon smolt survival similar in Columbia and Fraser rivers

... a variety of methods to evaluate survival. In the impounded reach of the Columbia River, the researchers used Passive Integrated Technology (PIT) tag data to evaluate survival between the upper and lower most dams. Tens of thousands of smolts in the upper river are routinely implanted with PIT tags ...

Scientists achieve first tracking of salmon from headwaters in Rockies through Pacific to Alaska

... between fresh and salt water." PIT tags The technologies used for the POST study are an alternative to Passive Integrated Transponder (PIT) tag detection systems installed at Columbia River dams starting in the 1990s, a system that provided the first accurate measurements of salmon survival ...

Conaway Lab identifies novel mechanism for regulation of gene expression

... . Uch37 is a "deubiquitinating enzyme" that can remove protein tags (called ubiquitin) from other proteins. The presence of one kind of ubiquitin tag on a protein can mark it for destruction, but others serve as marks to affect the activity of a protein. INO80 is a chromatin remodeling complex that ...

Severe climate change costs forecast for Pennsylvania, N.C., Tennessee, N.D.

... project specific long-term direct and ripple economic effects on North Carolina, North Dakota, Pennsylvania and Tennessee. In most cases, the price tag could run into billions of dollars. The studies combine existing data with new analysis and have been conducted by CIER in conjunction with the ...

TVA fertilizer technology used worldwide -- but few new products since 1970s

... of the fertilizer industry itself. With the price of energy increasing, we need to find cheaper, more effective ways to nourish food crops. The price tag for increasing productivity in Africa will be quite high. The fertilizer industry needs to do everything in its power to minimize that cost. Farmers ...
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