Suppression in Biological News

AGU journal highlights -- July 23, 2008

... 1. Fire suppression may have reduced carbon storage in western U.S. forests Active fire suppression since the early twentieth century has caused a ... The authors conclude that twentieth-century fire suppression and the resulting increase in stand density may ...

The myth of runner's high revisited with brain imaging

... in areas of the brain which are involved in the suppression of pain. The researchers, some of whom are also ... areas of the brain that are at the centre of the suppression of pain was not quite unexpected, but even this ... that endorphins facilitate the body's own pain suppression by influencing the way the body passes on pain ...

JCI table of contents: Aug. 16, 2007

... as CD4+CD25+Foxp3+ and known as Tregs. suppression by Tregs activated by IDO-expressing pDCs was ... death 1 (PD1) and its ligands. This mechanism of suppression is distinct from that used by Tregs activated by other stimuli. Importantly, immune suppression in tumor-draining lymph nodes was abrogated by ...

Stress puts double whammy on reproductive system, fertility

... hormone and follicle-stimulating hormone by the pituitary, and then a suppression of testosterone, estradiol and sexual behavior. In 2000, however, a new ... of RFRP levels in the dorsomedial hypothalamus area of the brain, and suppression of activity in the reproductive axis - the hypothalamus-pituitary-gonadal ...

Using hair to manage HIV/AIDS and predict treatment success

... levels of antiretrovirals in hair correlated with success in HIV viral suppression in treatment and did so better than any of the other variables usually ... help in measuring pill-taking, but its strong correlation with viral suppression could allow its use as an inexpensive, non-invasive method of monitoring ...

High blood sugar's impact on immune system holds clues to improving islet cell transplants

... of Alberta were the ones to find high blood glucose causes a short-lived suppression of the attack mode of the immune system followed by a slow return of ... become targets for their immune system. However, this generalized immune suppression puts patients at increased risk for infections, cancer and other diseases. ...

Scripps research team sheds light on immune system suppression

... 16 issue of the journal Cell Host & Microbe . The study described the suppression of this immune response in mice infected with lymphocytic choriomeningitis ... diseases in humans. "It's the first demonstration that a virus causes suppression of the interferon response in vivo," says the paper's senior author ...

Audience Selected as Silver Winner in This Year's Wall Street Journal Technology Innovation Awards and Winner of the Semiconductors Category

... processor company that enables clear communications anywhere with noise suppression technology based on the intelligence of the human hearing system. The ... of the Open Handset Alliance and the only one with advanced noise suppression technology. Investors in Audience include Vulcan Capital, NEA, Tallwood ...

International symposium explores fire suppression economics

... a dozen countries struggling to cost-effectively fight fires where past suppression has led to a worldwide abundance of vegetation that feed fires. In 2004, ... have included economists and social scientists who explored how fire suppression costs often bear little relation to values at risk, and how political and ...

Continuous oral contraceptives better at easing pain, bleeding

... effective in treating several medical conditions, where continuous ovarian suppression is desired, such as acne, hirsutism, premenstrual syndrome, endometriosis ... ovary syndrome, endometriosis and premenstrual syndrome, where additional suppression of the ovary or the endometrium is desired, and Legro noted that other ...

Umbilical cord blood cell therapy in an animal model of Alzheimer's disease

... New Rochelle, NY, March 26, 2008A novel strategy based on targeted immune suppression using human umbilical cord blood cells may improve the pathology and ... molecules. Human umbilical cord blood cell therapy was associated with suppression of CD40-CD40L activity, suggesting that this therapeutic approach ...

Methadone even at therapeutic levels can kill

... that some of the deaths in the first case group actually were due to suppression of breathing, especially during sleep. Previous studies have found that ... electrocardiogram and an assessment of the potential risk for respiratory suppression both awake and asleep. The OHSU research was based on the work of the ...

2 genes are important key to regulating immune response

... can help encourage AIDS in those infected with HIV. Also, excessive T-cell suppression can keep the immune system from destroying rogue cancer cells in people ... "anything that we can learn about IL-10 production -- and related T-cell suppression -- is a boon to medical research," Dr. Ma explains. Prior studies had ...

USDA Cooperative Agreement funds mosquito project at Rutgers

... the USDAs Mosquito and Fly Research Unit in Gainesville, Florida in its suppression of the mosquito. In addition, Rutgers scientists will collaborate with ... director of NJAES. These agencies will form focal points for expanding the suppression program to additional surrounding agencies in a snowball effect. The ...

La Jolla Institute discovers novel tumor suppressor

... leading to some types of leukemia." The findings are being published online today in the journal Cancer Cell in a paper entitled "Tumor suppression by Phospholipase C- 3 via SHP-1-Mediated Dephosphorylation of STAT5." Researchers from UC San Diego Cancer Center, University of Alabama and the ...

MicroRNAs help control HIV life cycle

... scientists tested the association of miR29 and HIV-1 by mutating both miR29 and its target region on the HIV virus. When either was altered, miR29s suppression of HIV replication and infectivity was reduced or eliminated. In addition, the team suppressed P-bodies in the cells and noted a similar effect. This ...

REGiMMUNE presents enhanced efficacy data in preclinical transplantation models

... killer T (NKT) cells. RGI-2001 is a proprietary liposomal formulation of KRN7000. RGI-2001 monotherapy has shown to induce antigen-specific immune suppression by inducing regulatory T cells (Tregs). Tregs are believed to play a central role in inducing and maintaining immune tolerance. The study was ...

System that regulates blood pressure is amiss in some healthy, young blacks

... stress, then recovered for two hours at MCG's Georgia Prevention Institute. "For reasons we don't understand, the black kids have improper suppression of this renin-angiotensin-aldosterone system," Dr. Diamond says. To make sure the "fight-or-flight" mechanism designed to raise blood pressure to ...

Researchers identify specific lung cancer susceptibility gene

... the original chromosome where the lung cancer markers were found contained about 100 genes, including several genes suspected to be involved in tumor suppression and cell growth. Using a genetically altered mouse model, researchers determined that when RGS17 was suppressed, lung tumors shrank, proving the ...

How tumor cells move

... developing new diagnostic methods or medication," says the pharmacologist. It could also be possible to develop an agent that prevents the genetic suppression of the signal factor in cancer cells. But first the researchers need to better understand how the signal factor itself is regulated in the cell. ...

Highlights from the March editions of ESA journals

... shrubs and grasses that fueled these burns. But human activities, such as livestock grazing, preferential logging of large trees and outright fire suppression or exclusion have led to changes in forest structure. Increases in tree density, smaller tree size and increased fuel load place as many as 10 ...

Researchers uncover 'obesity gene' involved in weight gain response to high-fat diet

... on obesity and related disorders," Mehta said. So far, mouse models lacking the protein have not shown any damaging side effects related to the suppression of the gene, Mehta said. He speculates that PKC beta could be a so-called "thrifty" gene left over from humans' days as hunter-gatherers, when the ...

Human DNA repair process recorded in action

... reconstruction. Because this protein is regulated by a gene linked to increased risk of breast cancer, BRCA2, it is also thought to play a role in suppression of that disease. With the ability to watch the assembly of individual filaments of Rad51 in real time, Kowalczykowski's team made a number of ...

Molecular mechanism of anaphylactic shock decoded

... in the cells that then cause the typical symptoms of an anaphylactic reaction. "In the genetic mouse model, we showed that surprisingly, selective suppression of the genes coding for the G proteins Gq and G11 in vessel walls protected the animals from the most severe anaphylactic reactions", stated ...

Mutant host cell protein sequesters critical HIV-1 element

... granules. "Taken together, these results demonstrate that stress granule induction and nef mRNA sequestration account for this translational suppression of Nef expression and offers a new strategy for development of anti-HIV therapeutics to buttress our fight against HIV/AIDS," concludes Dr. He. ...

Researchers engineer pancreatic cell transplants to evade immune response

... optimal, because ultimately the cells did get rejected," says Dr. Goldstein. "We are now looking at other viral genes that also contribute to immune suppression and are trying to identify the best gene combination to use." Dr. Goldstein views the current experiment as a proof of concept. "We were able to ...

Diverse landscapes are better: Policymakers urged to think broadly about biofuel crops

... including perennial trees and grasses as well as corn. Diverse landscapes often support higher levels of vital ecosystems services such as pest suppression and pollination. Our goal is to provide information so people can make more informed decisions." ...

More freedom to take risks: DFG funds the first Reinhart Koselleck Projects

... and biological psychology. He is particularly interested in automatic modelling and the systematic acquisition of auditory rules as well as the suppression of the brain's responses to autogenous auditory stimuli. By taking a primarily experimental approach, Schrger hopes to prove that the prediction and ...

Diverse landscapes are better: Policymakers urged to think broadly about biofuel crops

... including perennial trees and grasses as well as corn. Diverse landscapes often support higher levels of vital ecosystems services such as pest suppression and pollination. Our goal is to provide information so people can make more informed decisions." ...

Forest inventories in California include more than trees

... of the housing growth in the state over the last 10 years implying that forest managers will be tasked with fire hazard reduction, prevention, and suppression on an increasing area. Insects, diseases, air pollution, and fire shape the forested California landscape. More than 200,000 forested acres burned ...

The bonsai effect: Wounded plants make jasmonates, inhibiting cell division, stunting growth

... within days, and the new leaves grow to only one-half of their normal size although the size of leaf cells is unaffected. Unexpectedly, the suppression of cell division in the apical meristem occurs through a signal pathway initiated by the wound hormone, jasmonate, which is synthesised in the ...

Wildfires result in loss of forests reserved by Northwest Forest Plan

... plans will be needed to reduce risk of loss of older forests to fire. Federal managers should consider increasing fire prevention and suppression treatments in dry regions as climate change may lead to more fire. ...

UC Davis researchers discover a key to aggressive breast cancer

... the role of Lig-1 in breast cancer. They found that, when compared to healthy breast tissue, the regulator is significantly suppressed. "This suppression assists HER2 in its own over-expression and in driving the growth of cancer cells," said Colleen Sweeney, associate professor of biochemistry and ...

Text focuses on diagnosing infections in immunocompromised patients

... patients such as these require a unique set of healthcare solutions that take into consideration everything from the etiology and degree of immune suppression to the individual patient's nutritional status. A new text from ASM Press, Diagnostic Microbiology of the Immunocompromised Host, examines a wide ...

8 National Medals of Science awardees to be honored at gala, then the White House

... a co-founder of Linkabit, a small military contractor, and co-founded QualComm with Irwin Jacobs. He created the Viterbi Algorithm for interference suppression and efficient decoding of a digital transmission sequence, used by all four international standards for digital cellular telephony. QualComm is the ...

Prolonged effects of a warming anomaly on grasslands

... in the Reno greenhouse not only depressed plant growth and suppressed land carbon absorption in the treatment year but also resulted in prolonged suppression of plant growth and carbon absorption in the following year. ...

ACS PressPac -- Sept. 17, 2008

... male sex hormone, testosterone how injections of the hormone suppress production of sperm. Building on a previous study showing almost total sperm suppression with an injectable testosterone combined with a synthetic hormone called levonorgestrel (LNG), the researchers sought new insights into how hormones ...

Checking people at airports -- with terahertz radiation

... thus enables the calculability of the radiation incident on the detector. In order to obtain a sufficiently spectral purity of the THz radiation, a suppression of the infrared radiation of more than nine orders of magnitude is necessary. By using an FT-IR spectrometer, the transmittance for all filter ...

Bisphenol A linked to metabolic syndrome in human tissue

... a natural form of human estrogen. They found that exposing human tissues to BPA levels within the range of common human exposure resulted in suppression of a hormone that protects people from metabolic syndrome. "These results are especially powerful because we didn't use a single patient, a ...

Why a common treatment for prostate cancer ultimately fails

... cancer cells in culture. Nevertheless, the work might include some hints for improving patient care. Possibilities include studying whether androgen suppression therapy might be used to target only specific cells within the prostate, as well as checking whether drugs designed to prevent cancer from spreading ...