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stiffness in Biological News

American Chemical Society's Weekly PressPac -- May 14, 2008

... were in conflict, and the effect of mechanical stiffness of those surfaces had not been considered ... as compared to other polymers. Altering the stiffness of the polymers used in implants could lead to ... #2 FOR IMMEDIATE RELEASE Substrata Mechanical stiffness Can Regulate Adhesion of Viable Bacteria ...

MIT crafts bacteria-resistant films

... to surfaces by manipulating the mechanical stiffness of polymer films called polyelectrolyte ... All other factors being equal, mechanical stiffness of material surfaces increases bacterial ... on skin, and two types of Escherichia coli. stiffness has usually been overlooked in studies of how ...

Fast AFM probes measure multiple properties of biomolecules or materials simultaneously

... different applications, Degertekin can adjust the stiffness of the membranes. The best mechanical ... or biomolecules are obtained when the probe stiffness matches the sample stiffness, explained ... of the FIRAT probe, Degertekin can adjust the stiffness of the membranes, providing the ability to use ...

UC San Diego physicists tackle knotty puzzle

... repeated the experiment more than 3,000 times varying the length and stiffness of string, box size and speed of rotation. They classified the resulting ... The string forms concentric coils, like a looped garden hose, due to its stiffness and the confinement of the box. The free end of the string weaves through ...

'Invisibility cloak' could protect against earthquakes

... technology involves the use of concentric rings of plastic which could be fitted to the Earth's surface to divert surface waves. By controlling the stiffness and elasticity of the rings, waves travelling through the 'cloak' pass smoothly into the material and are compressed into small fluctuations in ...

Home tooth bleaching slightly reduces enamel strength

... and professionally provided products to be used in the home. The scientists used a specialized tool to apply force to test the enamel hardness and stiffness (the surface ability to bounce back), and an atomic force microscope to observe the tiny nanometer-scale effects on the teeth. The average loss of ...

Engineers develop method to disperse chemically modified graphene in organic solvents

... paints, inks and plastic electronics. Graphene is a unique atom-thick, carbon-based material.Its unusual combination of very high mechanical stiffness and strength, high and tunable electrical and thermal conductivity, and the fact that chemists can alter its chemistry readily means it has ...

Anakinra for rheumatoid arthritis: A modest benefit with some risk

... injection. In a Cochrane Systematic Review of five recent anakinra trials involving 2,876 patients, researchers found anakinra reduced pain and stiffness in patients, and helped to improve joint function, when compared to placebo. However, while around a quarter of patients experienced improvement in ...

Hypertension develops early, silently, in African-American men

... of ways, including: aortic blood pressure and stiffness brachial blood pressure carotid artery blood pressure carotid artery thickness and stiffness They found the African-American men had similar brachial blood pressure, compared to the white men, but they had significantly higher: ...

Clemson researchers advance nano-scale electromechanical sensors

... the National Institute for Standards and Technology is interested in promoting the Clemson method as one of the standard methods for measuring the stiffness of cantilevered beams," said Rao. ...

Lack of vitamin D linked to Parkinson's disease

... in several parts of the brain, particularly those that use the chemical messenger dopamine to control movement. The most common symptoms are tremor, stiffness and slowness of movement. These can be treated with oral replacement of dopamine. Previous studies have shown that the part of the brain affected ...

Reversible 3-D cell culture gel invented

... Research Scientist, added, "Another interesting property of the gel is its ability to support the extracellular matrix (ECM) secretions of cells. Gel stiffness is modulated by ECM secretions, and can be used to study ECM production by cells responding to drug treatments or disease conditions. "The ...

Normalizing tumor vessels to improve cancer therapy

... vessels are malformed, Ghosh wondered whether tumor capillary cells have lost the normal cells' ability to sense and respond to changes in matrix stiffness and distortion. To address this question, the researchers studied capillary cells isolated from mice prostate tumors, provided by Andrew Dudley, ...

Geisinger study: Inflammatory disease causes blindness

... patients with giant cells are three times more likely to experience Polymyalgia rheumatica, an inflammatory disorder that causes muscle aches and stiffness primarily in the arms, thighs and neck. "We need to learn more about how these giant cells work so we can limit the effects of this disease, which ...

Media highlights in the January issues of Biophysical Journal

... the cytoskeletal network is monitored by atomic force microscopy. This network spans all cells and thereby constitutes a supramolecular (mesoscopic) stiffness of the cell body. The idea of the authors was that vesicles, driven by motor proteins along a fiber, face a resistance of crossing fibers, which ...

Eat less or exercise more? Either way leads to more youthful hearts

... the left ventricle gained an increased capacity to expand to accommodate blood entering during diastole. In the calorie restriction group, the global stiffness of the left ventricle decreased, suggesting that the muscle and connective tissue of the heart more readily sprang back after the contraction phase. ...

High blood pressure in older adults traced to gene's effects in blood vessels

... actin is transformed from a loosely configured protein into a more rigid fibrous state. This change in actin's nature increases the size and the stiffness of smooth muscle cells. The cells undergo other changes that prepare them for cell division, but under these conditions, the vessel lining ...

'Heftier' atoms reduce friction at the nanoscale, study led by Penn researcher reveals

... nature of friction, which lacks a comprehensive model at the fundamental level. We know how some properties -- adhesion, roughness and material stiffness for example -- contribute to friction over several length scales, but this work reveals how truly atomic-scale phenomena can and do play a meaningful ...

New research on structure of bones raises questions for treatment of osteoporosis

... Trust in Newmarket, and the BAM Federal Institute of Materials Research and Testing, Berlin, have discovered that the characteristic toughness and stiffness of bone is predominantly due to the presence of specialized sugars, not proteins, as had been previous believed. Their findings could have sweeping ...

Herr receives Heinz Award for Technology, the Economy and Employment

... research group at the MIT Media Lab have developed a robotic foot-ankle prosthesis capable of propelling the wearer forward and varying its stiffness over irregular terrain, successfully mimicking the action of a biological angle, and, for the first time, providing amputees with a truly humanlike ...

Fever causing headaches for Aussie parents

... said it was important to closely monitor unwell children and seek medical advice if they were feverish under six months; suffered headache, neck stiffness or light hurt their eyes; had breathing difficulties; refused to drink; persistently vomited; were drowsy; suffered pain; had a rash of red-purple ...

Carnegie Mellon scientists find key HIV protein makes cell membranes bend more easily

... The lipid bilayers varied in their thicknesses, which affects the stiffness of cell membranes. The research was conducted at Cornell University’s ... to study FP-23 together with cholesterol, a molecule known to modulate the stiffness of cell membranes. ...

Exploring the molecular origin of blood clot flexibility

... How do blood clots maintain that precise balance of stiffness for wound healing and flexibility to go with the flow? Researchers at the ... to fibrin during clotting. A blood clot needs to have the right degree of stiffness and plasticity to stem the flow of blood when tissue is damaged, yet be ...

An elephant tail

... following a heart attack) over a 6-month period would decrease vascular stiffness and improve ejection fraction (a measure of how much blood the left ... myocardial infarction. It neither alters noninvasive measures of vascular stiffness nor improves left ventricular function. L-arginine therapy in older ...

Little known DNA repair enzyme may be a tumor suppressor gene

... following a heart attack) over a 6-month period would decrease vascular stiffness and improve ejection fraction (a measure of how much blood the left ... myocardial infarction. It neither alters noninvasive measures of vascular stiffness nor improves left ventricular function. L-arginine therapy in older ...

Use of amino acid supplement following a heart attack provides no benefit, may be harmful

... following a heart attack) over a 6-month period would decrease vascular stiffness and improve ejection fraction (a measure of how much blood the left ... myocardial infarction. It neither alters noninvasive measures of vascular stiffness nor improves left ventricular function. L-arginine therapy in older ...

Dinosaur hearing, listening to muscle noise, quieter cubicles

... noise in order to detect muscle stiffness, which in turn can provide information about neuromuscular disease, such as muscular dystrophy. Muscle stiffness was traditionally measured using external radiation sources (such as a vibrating piston). But the Scripps researchers use a process called passive ...

NIH announces phase III clinical trial of creatine for Parkinson's disease

... and Canada. PD is a degenerative disorder of the brain in which patients develop symptoms such as progressive tremor, slowness of movements, and stiffness of muscles. It affects at least one million people in the United States. Although certain drugs, such as levodopa, can reduce the symptoms of PD, ...

Researcher examines polymers created with poultry feathers

... as sodium sulfite and lubricants such as poultry fat. The solid-state properties can also be modified using divalent transition metal ions to affect stiffness and smell. These will help the keratin polymer be processed faster, be more aesthetically pleasing, and become water resistant and stronger for ...

3-D model reveals secrets of metastasis

... chopped to maintain the same speed. The complexity of this situation is further increased in that the cells become dramatically sensitive to the stiffness of the vines when the integrins are disabled and consequently tend to squeeze through the vines rather than pushing them aside. "Our findings ...

Carnegie Mellon researchers discover new cell properties

... contributes to the disease. Islam, an assistant professor of chemical engineering and materials science and engineering, says that the increased stiffness of the lamina may be caused by mutant proteins self-organizing into ordered structures within the HGPS lamina. "This could make the lamina stiffer ...

New molecule may aid in production of biofuels and fungi-resistant plants

... mollusks, algae, insects, fungi and yeasts and is a major structural component of these organisms. For example, chitin gives strength and stiffness to the shells/cuticles of shrimps and insects and to the cell walls of fungi. Because chitin is an abundant resource and, most importantly, because ...

Virginia Tech football player uses prototype cast

... spearheaded a partnership with this medical school in 2001, and formed the School of Biomedical Engineering and Science. Love said, "The resulting stiffness and strength of the laminated structures has not been fully evaluated, but qualitative testing has shown that these structures are demonstrably ...

Results of world's first gene therapy trial for arthritis show approach safe, feasible

... additional biochemical agents, which in turn cause more local inflammation. As inflammation builds, patients experience progressively worse pain and stiffness in their affected joints. To block this process, the team sought a way to prevent the main actor, IL-1, from binding to the synovial cells, and ...

When in danger humans are similar to a deer in the headlights

... Posturographic and electrocardiographic recordings were collected. The author found a significant reduction in body sway along with increased muscle stiffness following the unpleasant/mutilation block of pictures compared to the neutral pictures. The number of heartbeats per minute was also lower after ...

Scientists detect probable genetic cause of some Parkinson's disease cases

... brain signaling chemical (neurotransmitter). Without it, individuals can develop tremor or trembling in hands, arms, legs, jaw, and face; rigidity or stiffness of the limbs and trunk; bradykinesia, or slowness of movement; and postural instability or impaired balance and coordination. Patients may also have ...
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