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New cancer drug delivery system is effective and reversible

... Developing such antibodies is costly and time-consuming, however, and the process of attaching them to liposomes is difficult to control. Antibodies spur an immune response, requiring extra steps to create a useable therapeutic agent, and the ability of antibody-conjugated liposomes to bind to cancer ...

Mystery of bat with an extraordinary nose solved

... perceive their environment. Set to finish in February 2010, it is hoped the study's focus on wave-based sensing and communication in bats will help spur groundwork for innovations in cell phone and satellite communications, as well as naval surveillance technology. ...

Can a new implant coating technique create a new six million dollar man?

... and fixation of the implant, and also prevents poisonous materials from leaking from the metal of the implant into the blood stream. Could spur new bone growth Prof. Eliaz has discovered that his method of coating circumvents the disadvantages of plasma- spraying. The electrochemical ...

NIH expands Human Microbiome Project; funds sequencing centers and disease projects

... funded through the 2009 American Recovery and Reinvestment Act. The ARRA funds that support this center will provide a much needed investment to spur advances in the understanding of how microorganisms that live in or on our bodies affect our health. In addition, the Broad Institute of MIT/ ...

Researchers describe 'implausible' chemistry that produces herbicidal compound

... to one penicillin, scientists tinker with the structure so that the organism is susceptible again." The researchers hope the new findings will spur the development of much smaller, cheaper and more efficient synthetic catalysts that can also sever C-C bonds in one step. "Every time we find ...

Research team finds important role for junk DNA

... had been viewed as the "dispensable genome" are actually performing functions that are central for the organism. They have concluded that the genes spur an almost acrobatic rearrangement of the entire genome that is necessary for the organism to grow. It all happens very quickly. Genes called ...

New drug shows promise in treating drug-resistant prostate cancer

... cancer are diagnosed each year in the United States. The male hormones testosterone and dihydrotestosterone, which are also known as androgens, spur the growth of prostate cells, and drugs that block the receptors for these hormones are the most common treatment for the disease in its advanced, ...

New medications show promise in treating drug-resistant prostate cancer

... of prostate cancer are diagnosed each year in the United States. The male hormones testosterone and dihydrotestosterone -- also known as androgens -- spur the growth of prostate cells, and drugs that block the receptors for these hormones are the most common treatment for the disease in its advanced, ...

CSHL team develops mouse models of leukemia that predict response to chemotherapy

... genetic makeup, or 'genotype,' influences the outcomes of treatment, these models might help improve how existing drugs are used in people, and spur the design of more effective therapies," Lowe observes. "The new models are an important preclinical tool that will allow knowledge gained from ...

New drug agent knocks out multiple enzymes in cancer pathway

... had a very low chemical affinity for bone. In humans, compounds like BPH-715 and zoledronate have an added benefit in fighting cancer: They spur the proliferation of immune cells called gamma delta T-cells, which aid in killing tumor cells. "The new drugs are about 200 times more effective ...

Smithsonian scientist warns that palm oil development may threaten Amazon

... forest to plantations releases at least 60 percent of above-ground biomass. While Laurance and Butler are concerned that oil palm development could spur large-scale forest conversion in Amazonia, they propose ways to temper the most serious environmental impact of the expansion. "Developers can be ...

A worm-and-mouse tale: B cells deserve more respect

... array of unexpected functions for B cells. In the laboratory, she has found that B cells produce chemical signaling molecules known as cytokines that spur other immune cells in the body to action. Her team has also shown that B cells are crucial for presenting to T cells snippets of proteins from ...

CSHL researchers identify gene that helps plant cells keep communication channels open

... gene was turned on, the production and accumulation of callose decreased. GAT1 counters oxidative stress One of the distress signals that spur cells to synthesize callose are oxygen free radicals the same cell-damaging molecules that have gained notoriety as a major cause of cell death and ...

James Thomson receives 2008 Massry Prize honoring stem cell researchers

... human adult skin cells. Like their source human ES cells, the iPS cells can become any type of cell in the body. Their discovery has helped spur the development of regenerative medicine and eased much of the controversy surrounding stem cell science by eliminating the need to use human embryos ...

Cancer cell 'bodyguard' turned into killer

... said that this new way of altering a protein so it injures a cell rather than merely disables it "is very unusual." He added that this finding would spur researchers to develop drugs or stable peptides that act on Bcl-2 at the Nur77 binding site. "Quite conceivably, individual cancers may respond ...

UD researchers show that plants can accumulate nanoparticles in tissues

... in the environment--whether it poses potential harm to human health depends on many factors. This is a preliminary study, which we hope will spur additional interdisciplinary research by the scientific community." The researchers chose pumpkins for the study, Jin said, because they take in a ...

What makes an axon an axon?

... about what keeps these structures distinct. In cultured neurons, Hedstrom et al. used RNAi to cut production of ankyrinG, a protein that helps spur formation of the AIS. Loss of ankyrinG caused the AIS to disappear. For example, sodium channels that normally crowd the AIS's plasma membrane ...

Researchers document world's mammals in crisis

... efforts can be measured," said Smith, who initiated the database that was used to inventory the world's mammals. "This effort hopefully will spur greater attention on the conservation of mammals and the habitats they occupy, for the benefit of all biodiversity." ...

The dietary supplement genistein can undermine breast cancer treatment

... botanical components and extracts marketed as supplements to assist "female libido enhancement" and sold without a prescription appeared to spur breast cancer tumor growth at low doses, while having no effect on tumors at high doses. That study appeared last year in Food and Chemical ...

Gap junction protein vital to successful pregnancy, researchers find

... factor (VEGF), is essential to angiogenesis. In the absence of Cx43, Laws found, the cells failed to differentiate or to produce enough VEGF to spur blood vessel growth. "The formation of these new blood vessels is extremely critical for embryonic growth at this stage of pregnancy, when the ...

How 'secondary' sex characters can drive the origin of species

... resonant baritone -- are known as secondary sexual characters. Evolutionary biologists believe changes in copulatory organ size and shape can spur speciation by making individuals from different populations sexually incompatible. Native to Italy, O. taurus exists in other parts of the world ...

Why a common treatment for prostate cancer ultimately fails

... Some of the drugs given to many men during their fight against prostate cancer can actually spur some cancer cells to grow, researchers have found. The findings were published online this week in a pair of papers in the Proceedings of the ...

UH researchers win top prize for research with humanitarian applications

... but sometimes they can be pretty nasty." While microbial communities are ordinarily relatively stable, climate and environmental factors can spur the success of some and the destruction of others. In agriculture, for instance, changes in diverse microbial communities can cause complete crop ...

USC researchers identify alternate pathway that leads to palate development

... molecules within the cell. These signaling molecules then travel to the nucleus, the cell's control center, and prompt DNA expression in order to spur changes in the cell. "For instance, we've learned that when someone has a haploid insufficiency and is missing one copy of the TGF- gene, he or ...

Ivory poaching at critical levels: Elephants on path to extinction by 2020?

... comes from in the first place, before it enters the complex, global crime trade network. Public support is crucial to helping reduce demand and to spur the needed enforcement help from the West. However, Wasser believes that news reports about the need to cull excess elephants from managed ...

Weill Cornell science briefs June/July 2008

... this well-known protein. The scientists studied colon cancer cells within a mouse model to make their observations. Moving forward, the findings may spur research to identify new biomarkers, specific to metastatic cancer stem cells, which may lead to the development of drugs that target metastatic ...

Estrogen helps drive distinct, aggressive form of prostate cancer

... gene fuses with an oncogene -- a type of gene that causes cancer," he explains. Experts have long understood that male hormones help spur prostate cancer -- in fact, androgen-deprivation therapy is a first-line treatment against the disease. And yet the disease can progress despite ...

Some biofuels might do more harm than good to the environment, study finds

... students and other biologists, Groom said. The primary goals are to establish a logical basis to evaluate options for biofuel development and to spur new research to find the most ecologically promising alternatives. "We don't want to make new mistakes. If we don't ask the right questions to ...

Shell-breaking crabs lived 20 million years earlier than thought

... claw moved faster and could manipulate prey into position. Also, the curved tooth increased the power of the claw. Dietl hopes the discovery will spur other researchers to search for similar examples of these curved tooth structures from the Late Cretaceous period, just prior to the extinction of ...

UTMB inventions win University of Texas System commercialization awards

... by University of Texas Medical Branch at Galveston researchers have won $50,000 awards from the Texas Ignition Fund, a new program designed to spur the commercialization of technologies developed at UT System institutions. One of the inventions, conceived by UTMB anesthesiology professor ...

Sanitation investment in poor countries would yield $9-to-1 benefits in productivity, health: UN

... one national coordinating body, formulating a single, country-wide sanitation plan, and putting into place a transparent monitoring framework could spur and drive progress. Market sanitation and hygiene and focus on long-term behaviour change Health-oriented information campaigns have been less ...

AGU journal highlights -- Feb. 26, 2008

... Research Letters (GRL) paper 10.1029/2007GL032692, 2008; http://dx.doi.org/10.1029/2007GL032692 3. Subtle wind variations may spur abrupt climate change Simulating the climate during the Last Glacial Maximum (LGM), which occurred roughly 21,000 years ago, is a major challenge ...

Global trade in tiger shrimp threatens environment

... working with local governments, have made major commitments to expanding aquaculture in the hope that such activities would alleviate poverty and spur economic growth in these areas. But the Swedish human geographer Daniel A. Bergquist has shown, using Sri Lanka and the Philippines as examples, ...

Singapore's BIOPOLIS and FUSIONOPOLIS on stage in Boston this week

... the health, lifestyles or economy of Singaporeans and the available or potential research strengths that we have in those areas, said Mr. Lim. To spur talented Singaporean students interest for careers in science, A*STAR supports a science education program that encompasses public schools as well as ...

Scientists associate 6 new genetic variants with heart disease risk factor

... to help predict a patients genetic risk of heart disease, the six new loci may point to novel aspects of cholesterol metabolism and could also spur new cholesterol-lowering drugs. Heart disease is a leading cause of death around the world. Researchers have known for decades that one of the ...

Biotech Co. founded by UCLA Scientists to be acquired by Astellas, Pharma Inc.

... with $8 million in seed money from private donors and angel investors, many of whom were grateful patients of the UCLA physicians who had helped spur the development of novel gene-based therapies for prostate cancer, the most common cancer in men. As clinicians and scientists, we wanted to ...

Environmental exodus

... three case studies the US Dust Bowl in the 1930s; Bangladesh since the 1950s; and Hurricane Katrina in 2005 shows that although climate change can spur large population movements, public policy can alleviate the pressures of ecomigration. Indeed, if a country can invest in areas affected by ...

Are current projections of climate change-impacts on biodiversity misleading?

... evenly distributed? Geographic patterns of species diversity and their underlying processes have intrigued scientists for centuries, and continue to spur scientific debate. Studies carried out over the past 20 years have led to the conclusion that species diversity is best predicted by contemporary ...

Genome study charts genetic landscape of lung cancer

... disease, including more than 150,000 in the United States. New approaches to treatment rely on a deeper understanding of what goes wrong in cells to spur cancer growth. Through decades of research, it has become clear that lung cancer like most human cancers stems mainly from DNA changes that accrue ...

Triage study challenges notions of emergency medical response to disaster

... a mass casualty event is probably one that takes into account a variety of local and regional factors, which means that use of the model should spur regional collaboration and information sharing. "We hope that this type of modeling study will be used to help disaster response teams plan effective ...
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