shuttle

Discovery of key protein's shape could lead to improved bacterial pneumonia vaccine

..., this germ binds to pIgR and pushes this antibody shuttle backthrough the cell to the bloodstream. Once at the other side of thecell, the pneumococcus breaks free of pIgR and enters the blood, whereit can multiply and infect the body. S. pneumoniae is the only bacterium known to use CbpA to invade humancel...

New comparative toxicogenomics database

..., this germ binds to pIgR and pushes this antibody shuttle backthrough the cell to the bloodstream. Once at the other side of thecell, the pneumococcus breaks free of pIgR and enters the blood, whereit can multiply and infect the body. S. pneumoniae is the only bacterium known to use CbpA to invade humancel...

Molecular Motors Cooperate In Moving Cellular Cargo, Study Shows

...ght on the tiny movements of molecular motors that shuttle material within living cells. The motors cooperate in a delicate choreography of steps, rather than engaging in the brute-force tug of war many scientists had imagined. "We discovered that two molecular motors -- dynein and kinesin -- do not compet...

Motor transport in bio-nano systems

... cell center to the periphery and vice versa, some shuttle between different organelles or cellular compartments. An extreme case is provided by the long-ranged transport of vesicles and organelles along the axons between our nerve cells, which can be as long as half a meter. All of these movements are based...

No small feat: First ever gene therapy success for muscular dystrophy achieved

...e viral vectors ?disarmed viruses that are used to shuttle genes into cells. But the team found a good stand-in in a similar protein called agrin that when miniaturized could be inserted inside an adeno-associated virus (AAV) vector. Dr. Xiao's laboratory is known for its work developing this vector, which t...

Deep treasure to be found in Oculina Bank

... 12-18 on board the M/V Liberty Star, a NASA space shuttle support ship operated by United Space Alliance and normally used to retrieve spent solid rocket boosters. A second related expedition is planned for May 2006. To explore the reefs, researchers will be using NURC's Phantom SII Remotely Operated Vehicl...

T-rays: New imaging technology spotlighted by American Chemical Society

...imaging technology, which can spot cracks in space shuttle foam, see biological agents through a sealed envel...ng has also successfully detected defects in space shuttle foam. Other T-ray applications could enable the label-free characterization of genetic material, det...

Lactic acid not athlete's poison, but an energy source - if you know how to use it

...on between the transporter molecules - the lactate shuttle - and the enzymes that burn lactate. In fact, the cellular mitochondrial network, or reticulum, has a complex of proteins that allow the uptake and oxidation, or burning, of lactic acid. "This experiment is the clincher, proving that lactate is the ...

Scientist-astronaut sends T-cells into space

...ans Affairs, and a payload specialist aboard space shuttle flight STS-40 in 1991, will send human T-cells up ...equent experiments aboard Skylab and several space shuttle missions, including Fulford's, confirmed that T-cells do not activate properly in microgravity. "I...

U of M study examines kidney stone prevention in astronauts

As the space shuttle Discovery prepares to launch on July 1, researchers at the University of Minnesota have identified a way for astronauts to reduce their risk of developing kidney stones while in space. Astronauts lose calcium in their bones and strength in their mus...

Microscopic passengers to hitch ride on space shuttle

When space shuttle Atlantis rockets into space later this week, it wi...he 'Microbe' experiment, part of the STS-115 space shuttle mission scheduled for launch Aug. 27, will study three common microorganisms -- Salmonella typhimuri...

Sandia work launched on space shuttle shows live cells influence growth of nanostructures

... on the recently completed mission of the US space shuttle Discovery. On the Space Station, experiments will be performed to determine their longevity when exposed to the extreme stresses of the radiation and vacuum of outer space. Of the NASA mission, Brinker says, "Ordinarily, exposed to such extreme con...

Salk scientists untangle steroid hormone signaling in plants

...ctivating growth genes. "All of a sudden the 'BES1 shuttle model' no longer made sense," says Vert, adding th...ally activate BES1, but instead of freeing BES1 to shuttle into the nucleus, it is now clear that the crucial activation step occurs in the nucleus where BES1 ...

Ozone recovering, but unlikely to stabilize at pre-1980 levels, says study

...ctivating growth genes. "All of a sudden the 'BES1 shuttle model' no longer made sense," says Vert, adding th...ally activate BES1, but instead of freeing BES1 to shuttle into the nucleus, it is now clear that the crucial activation step occurs in the nucleus where BES1 ...

Light-sensitive photoswitches could restore sight to those with macular degeneration

...hanging molecules to proteins, developing means to shuttle these photoswitches into cells, building artificial genes that can be inserted into a cell's DNA to express the photoswitches in the correct cell, and searching for ways to get light into areas of the body not possible to illuminate directly. "I'm ...

The first tree genome is published: Poplar holds promise as renewable bioenergy resource

...l from the air by producing trees that effectively shuttle and store more carbon below ground in their roots and the soil. Moreover, bioenergy crops re-absorb carbon dioxide emitted when biofuels are consumed, creating a cycle that is essentially carbon neutral." Poplar's extraordinarily rapid growth, and i...

NYU biologists identify gene that coordinates two cellular processes

...ar envelope, the MEL-28-GFP fusion was observed to shuttle between the nuclear periphery and the chromosomes during cell division. Additional functional tests showed that mel-28 was essential to both the integrity of the nuclear envelope and to proper chromosome segregation. This study served as a validation...

Major link in brain-obesity puzzle found

...all-trades in the world of cell signaling. Able to shuttle between the area just beneath the cell membrane and the nucleus, it can bind to many different molecules and facilitate signaling. Specifically, it can bind to a variety of molecules called tyrosine kinases, including ones that serve as receptors ...

Stem cell therapy shows promise for rescuing deteriorating vision

...test the cells as a continuous delivery system" to shuttle an agent known as glial cell line-derived neurotrophic factor or GDNF, Lund explains. "It's not a sensible thing to inject the eyes many times over years. The idea was to use the cells as a continuous delivery system, but we found they work quite wel...