Association of herpesvirus with lung disorder questioned
...y be different from that in the United States. The sensitivity and methods of the tests used in each study may also have differed. "We hope that our results provide scientists with another perspective on the potential causes of primary pulmonary hypertension," Dr. Katano said. "Further studies are required to c...Novel technology detects human DNA mutations
... the use of nanoparticles to dramatically increase sensitivity in our other proprietary applications -- such as bio-barcode for ultra sensitive detection of proteins -- demonstrate the broad applicability of nanotechnology and its potential to markedly advance the state-of-the-art in nucleic acid and proteomic r...Imaging Lymph Nodes with Nanoparticles
... The results areencouraging: the analysis showed a sensitivity of 98% (95% confidenceinterval, 88%?9%) and a specificity of 92% (95% confidence interval,87%?6%). The advantages of automating this procedure are substantial,not least because it can remove the problem of different observersassessing data differentl...Placenta Is A Rich Source Of Blood Stem Cells
...ed in the values of excellence in patient care and sensitivity to the complex needs and diversity of children and families. Children's also is the primary pediatric teaching affiliate of Harvard Medical School. For more information about the hospital visit: http://www.childrenshospital.org/research. ...Study shows nanoshells ideal as chemical nanosensors
'Nanoshells' enhance sensitivity to chemicaldetection by factor of 10 billionNew research published in the Proceedings of the National Academy ofScience finds that tailored nanoparticles known as nanoshells canenhance chemical sensing by as much as 10 billion times. That makesthem a...Development of portable infectious disease detector
...rete--oxygen, glucose and lactic acid--with enough sensitivity tomonitor the health of a few thousand cells confined in a small volume.(For more detail see "New device can help defend against novelbiological agents" at[http://exploration.vanderbilt.edu/news/news_microphys.htm].)Under the leadership of Franz Baud...Alcohol's effects on gene expression in the central nervous system
...d biological bases of alcohol's rewarding effects, sensitivity to the effects of alcohol, development of tolerance to the effects of alcohol, development of alcohol dependence, and alcohol withdrawal severity," he said. "For the average reader, knowing which genetic profiles might contribute to excessive alcohol...Study of genomic DNA leads to new advances in cancer diagnostics
...sing the malignant potential of cells based on the sensitivity of cellular DNA to enzyme digestion. The article by Andrew J. Maniotis et al., "Chromatin sensitivity to Alu I restriction enzyme decreases with malignancy and is regulated by the extracellular matrix a...World's largest rainforest drying experiment completes first phase
...second harvest will increase. Third, the observed sensitivity of large canopy trees in the forest to drought is ...the experiment, when soil water was depleted. This sensitivity of large trees to drought means that a decline in rainfall will likely push this tall, green, lush r...Applied Biosystems Introduces Advanced Gene Expression Service Provider Program
...genes and achieves more than a 10-fold increase in sensitivity while using less sample for the detection of genes expressed at very low levels compared with conventional fluorescent microarrays. The system uses a chemiluminescence-detection instrument, software, and chemistries to deliver unambiguous gene result...Harnessing microbes, one by one, to build a better nanoworld
...genes and achieves more than a 10-fold increase in sensitivity while using less sample for the detection of genes expressed at very low levels compared with conventional fluorescent microarrays. The system uses a chemiluminescence-detection instrument, software, and chemistries to deliver unambiguous gene result...Children's taste sensitivity and food choices influenced by taste gene
...ariation in a taste receptor gene influences taste sensitivity of children and adults, accounting for individual ...05 issue of Pediatrics, researchers compared taste sensitivity and food-related behaviors across three genotypes of the TAS2R38 gene, which encodes a taste recepto...Researchers develop rapid diagnostic tool for pathogen identification
...ons.?/p> “The high multiplexing capability and sensitivity of the approach is provided by using the digital molecular weights of small molecules to code for the identity of the pathogens and detection of the molecular tags with high sensitive mass spectrometry, which can be potentially miniaturized,?stated c...Effective Cancer Treatments Follow The Clock
...discovered a molecular mechanism that explains why sensitivity to anti-cancer drugs changes with the clock. They ...t Clock-mutant and Bmal1-knockout mice showed high sensitivity to the drug at any time it was administered ?as if the drug were administered early in the morning o...Robot-based system developed at Carnegie Mellon detects life in Chile's Atacama desert
... in the samples. He also is testing the bacteria's sensitivity to ultraviolet (UV) radiation. One hypothesis is that the bacteria may have greater UV resistance because they are exposed to extreme UV radiation in the desert environment. This characterization also may explain why such a high proportion of the bac...Nanoscale Diagnostic Sets Sights on Alzheimer's
...ional Academy of Sciences. Because of the extreme sensitivity of the BCA process that Mirkin's team developed, t...ive detector. Each DNA piece greatly increases the sensitivity of the test and its potential to tell doctors a patient carries the ADDLs. According to the researc...Light therapy may combat fungal infections, new evidence suggests
... the importance of genes with known roles in light sensitivity of another, distantly related fungus. Yeast strains lacking one of those genes, known as white collar 1 (BWC1), mated equally well in the light or the dark, implicating that gene in the fungus' ability to sense light. BWC1 also functions in the fungu...Duke engineers develop new 3-D cardiac imaging probe
...ich, combined with the 504 sensors, provides great sensitivity and a sharp image, Smith said. And because the image is large enough to encompass the whole volume of the heart, fewer "pictures" need to be taken. This may shorten patient time in clinics, he said. ...Scientists journey to southern Africa to unravel the secret world of elephant communication
...ped frogs, kangaroo rats and golden moles. Seismic sensitivity also has been observed in elephant seals--huge mar...runk and feet offers new clues to elephant seismic sensitivity In addition to her fieldwork, Caitlin O'Connell-Rodwell also is conducting laboratory studies on el......y researchers who want to achieve a high degree of sensitivity and precision in their experiments. ...Virus-host interactions at sea effect global photosynthesis
...y researchers who want to achieve a high degree of sensitivity and precision in their experiments. ...B-15A collides with Antarctic ice tongue
...y researchers who want to achieve a high degree of sensitivity and precision in their experiments. ...Measuring Enzymes At End Of Cancer Pathway Predicts Outcome Of Tarceva, Taxol
...he CDK2 enzyme strongly correlated with a cancer's sensitivity to Tarceva. That means testing activity of CDK2, ...ncreased activity of CDK1 correlated with a cell's sensitivity to Taxol. The CDK enzyme plays a role in cell division, and researchers believe that it functions i...Product improves peptide identification for proteomics research
...pectrometers. "The high resolution, scan speed and sensitivity of the LC/MSD Trap XCT Ultra make it a powerful to...nd environmental analysis, which require excellent sensitivity and fast scanning capability." The LC/MSD Trap XCT Ultra, which is based on an advanced multipole i...Affymetrix Launches New Globin-Reduction Kits and Protocol Developed with PreAnalytiX
...g target preparation significantly increases assay sensitivity on GeneChip arrays. The GeneChip Globin Reduction Protocol links PreAnalytiX' already proven standard for whole blood collection, stabilization and isolation of RNA with Affymetrix' leading product line for microarray-based analysis of whole blood c...Whole-body MRI Takes Less Than 20 Min To Scan A Patient's Entire Body For Cancer Spread To Bone
...s, the researchers found that whole-body MRI had a sensitivity of 100%, a specificity of 95% and an accuracy of 9...moving table and fast software. It offers a better sensitivity and higher specificity in detecting bone metastasis than other methods,?said Joan C. Vilanova, MD, l...Mutation in clams protects against paralytic shellfish poisoning but raises human health risk
...me from areas with a history of red tides had less sensitivity to the toxins than did clams from an area with no ... from exposed the population showing markedly less sensitivity to the toxins. Tracking these differences down to the genomic level and comparing DNA sequences fro...Brain Scan Study of Smokers Reveals Signature of Craving
...r suggests the difference may lie in their brains' sensitivity to drug cues. The researchers found that smokers w...avings after deprivation also exhibited heightened sensitivity to smoking-related images compared to those who craved cigarettes less. "These findings are excitin...Blink, and the brain misses it
...? In the 1980s, scientists discovered that visual sensitivity begins decreasing immediately before a blink, but the brain mechanisms underlying this process have until now remained unclear. As they report this week, Davina Bristow and a team of scientists at University College London led by Dr. Geraint Rees may...Evolution of taste receptor may have shaped human sensitivity to toxic compounds
...ressed in individual cells, conferred an increased sensitivity toward several harmful compounds found in nature. The work strongly supports a pivotal role for bitter-taste perception in toxin avoidance in humans, an attribute that could have come into particular play during periods of expansion into new environ...Environmental chemical cocktail may sabotage sperm
...in the body rather than in the laboratory, but the sensitivity of human sperm to these chemicals means that further investigations should be carried out to determine whether such environmental compounds might contribute to a decrease in human fertility. Other scientists have investigated the negative impact of e...Thinking the pain away? Study shows the brain's painkillers may cause 'placebo effect'
...r time increased -- indicating a reduction in pain sensitivity that the subjects were not aware of. In other words, thinking they were getting a pain drug actually allowed the participants to tolerate even more pain-inducing concentrated salt water than before. After each scan, the researchers asked the partici...Fruit fly studies open new window on cancer research
... have found a family of proteins that enhances the sensitivity of a cell to a hormone that can trigger abnormal growth and cancer. Their discovery could lead to a completely new approach to tackling some cancers and the development of new drugs to stop uncontrolled growth in a wide variety of tumour cells. The ...Lance Armstrong through a physiological lens: hard training boosts muscle power 8%
... CS maximal activity, improved respiratory control sensitivity during exercise as classically proposed (by J Holloszy and E. Coyle)?We hope that the present observations will stimulate additional research to clarify the precise nature, time course, and significance of the physiological adaptations induced by sho...New technique rapidly detects illness-causing bacteria
...ves researchers a powerful tool for increasing the sensitivity of the analysis. The method may help researchers and companies that are in the business of tracking food-borne pathogens, allowing technicians to determine a source quickly. It may also help to analyze a throat culture swab, to tell if someone has a...A novel method to measure circadian cycles
... human circadian cycle: 24.5 hours. Because of the sensitivity of their method, Schibler and colleagues also confirmed that, for both humans and mice, circadian rhythms vary substantially between individuals. This suggests that the genetics of the circadian clock likewise varies between individuals. Unlike an ...Clear rules needed to govern deep sea bioprospecting: UNU
...deep seabed bioprospecting, combined with a strong sensitivity to countries' freedoms in international areas." "Ethical concerns have been raised with regard to the status of deep seabed genetic resources," says Salvatore Arico of UNESCO, a Visiting Research Fellow at UNU-IAS and a lead author of the report wit...A Father’s Day Gift: Free DNA Paternity Testing
...deep seabed bioprospecting, combined with a strong sensitivity to countries' freedoms in international areas." "Ethical concerns have been raised with regard to the status of deep seabed genetic resources," says Salvatore Arico of UNESCO, a Visiting Research Fellow at UNU-IAS and a lead author of the report wit...Weight control protein may yield antiobesity drugs
...SH2-B as an important positive regulator of leptin sensitivity inside cells of the brain region known as the hypo...energy balance and body weight by enhancing leptin sensitivity in animals, Rui said. Mice lacking a functional copy of the SH2-B gene were smaller at birth than n...Global warming increases oyster sensitivity to pollution
...search has shown that global warming increases the sensitivity of oysters to metal pollution, causing a deadly threat to populations in polluted areas. Dr. Gisela Lannig from the University of North Carolina, USA, will present her work on cadmium poisoning in eastern oysters (Crassostrea virginica) on Monday 11t...'Gadonanotubes' greatly outperform existing MRI contrast agents
... percent of MRIs. The contrast agents increase the sensitivity of the scans, making it easier for doctors to deliver a diagnosis. Gadolinium agents are the most effective agents and the most commonly used. In the future, the researchers hope to use existing methods of attaching disease-specific antibodies and p...Scientists create digital bacteria to forge advances in biomedical research
...discovered that one type of protein controlled the sensitivity of E. coli's chemotaxis system, which helps the ba...ged the level of that protein, it would change the sensitivity of the cell," Emonet said. Subsequent laboratory experiments came out exactly the same way. Sometim...Retina adapts to seek the unexpected, ignore the commonplace
...ses to novel stimuli, the researchers computed the sensitivity of individual ganglion cells to various scenes. For most cells, sensitivity to a novel scene was greater than sensitivity to control scenes to which the animals had already bee...Women feel more pain than men, research shows
...relationship between gender differences in anxiety sensitivity and pain. Anxiety sensitivity is the tendency to be fearful of anxiety-related sensations (e.g., rapidly beating heat), and seems ...New results validating Pall prion reduction filter disclosed at ISBT Congress
...ts that would meet the required criteria including sensitivity and specificity. The implementation of donor screening would be problematic without the availability of confirmatory assays to inform discussions with potentially infected donors. Prion Reduction Confirmed Sam Coker, Ph.D., Principal Scientist of P...Female butterflies go for sparkle -- not size -- when choosing to mate
... not found desirable by females, indicating strong sensitivity to a set of rather narrowly defined features, such as eyespot pupils that measure approximately half of one millimeter. The most conclusive finding resulted when the researchers painted the white pupils in male eyespots on the dorsal side with a pla...Purdue's gold nanorods brighten future for medical imaging
...is important to have a reliable technique that has sensitivity at the single-particle level," Wei said. "The gold nanorods demonstrate that Cheng's nonlinear imaging methods are capable of this level of detection." The research has been funded by the National Institutes of Health and is affiliated with the Birc...Many cats unaffected by catnip, C&EN reports
...y, the world's largest scientific society. Catnip sensitivity is inherited, says Carolyn M. McDaniel, a veterinarian at the Feline Health Center at Cornell University in Ithaca, N.Y. A kitten with only one catnip-sensitive parent has a one-in-two chance of developing the sensitivity; if both parents have the se...UT Southwestern researchers develop screening test for cells that activate immune system
...ssay is unique from other conventional ones in its sensitivity and cost- and time-efficiency," said Dr. Akira Takashima, professor of dermatology and vice chairman for research and head of the project. Dendritic cells (DCs) are considered key to developing future vaccines that can either mimic the body's natura...Breath of the dragon: ERS-2 and Envisat reveal impact of economic growth on China's air quality
...phere. While GOME demonstrated the first satellite sensitivity to tropospheric nitrogen dioxide, SCIAMACHY possesses superior performance, with a spatial resolution of 60 x 30 kilometres compared to 320 x 40 km for its predecessor. SCIAMACHY also observes the atmosphere in two different ways - downwards or nad...Molecular cabal contributes to stroke damage
...icular ASIC, called ASIC1a, to greatly enhance its sensitivity to the acid induced by ischemia. This increased sensitivity causes the ASIC channel to open and flood the neuron with lethal doses of calcium. Importantly, the...NIAID researchers show how promising TB drug works
... screened for PA-824-resistant M. tb that retained sensitivity to a close relative of PA-824. Within this subgroup of PA-824-resistant bacteria, the team identified those mutant strains with FGD1 and F420. The investigators reasoned that resistance to PA-824 in mutants possessing FGD1 and F420 must be due to a m...Bacteria which sense the Earth's magnetic field
... the wild type in shape, size, and number. But the sensitivity of the magnetic field sensor function was disrupted; the cells could only orient themselves weakly in the magnetic field. Inspection by an electron microscope showed that the mutants' magnetosome crystals did not build a perfectly organised linear ch...Nanoparticles, nanoshells, nanotubes: How tiny specks may provide powerful tools against cancer
... planning to perform animal studies, examining the sensitivity of the antibody-nanotube system in detecting cancer cells in the blood and in detecting specific types of cancer cells shed in the blood from tumors. Immunonanoshells for Selective Photothermal Therapy (Abstract 3198) and Nanoshells for Combined Ca...PET imaging reveals the immune system at work
... the liver or the spleen. With this technique, the sensitivity for monitoring the immune system is incredible because you're seeing the whole body." That global perspective makes it possible to see critical ancillary responses in addition to the specific cellular battles of the immune system at the site of a tu...Jefferson biologist coaxing human embryonic stem cells to make dopamine with simpler, faster method
... the liver or the spleen. With this technique, the sensitivity for monitoring the immune system is incredible because you're seeing the whole body." That global perspective makes it possible to see critical ancillary responses in addition to the specific cellular battles of the immune system at the site of a tu...Discovering the first steps in transcription-coupled repair
...iseases with a common feature: both entail extreme sensitivity to sunlight. However, in XP there is loss of ability to repair damage to DNA caused by ultraviolet radiation throughout the genome, whereas in CS the global repair mechanism is intact but transcription-coupled repair is defective. Thus active genes c...Algal protein in worm neurons allows remote control of behavior by light
...ments, the researchers took advantage of the light sensitivity of the algal channel protein by introducing expression of a modified form of ChR2 in specific C. elegans neurons and muscle cells. The researchers found that when this form of ChR2 was expressed in muscle cells, blue-light activation of the protein w...Carnegie Mellon U. transforms DNA microarrays with standard Internet communications tool
...n captured by DNA microarray analysis with greater sensitivity and specificity. The work holds great promise for ...urning on. Our protocol will offer greater overall sensitivity in detecting the expression of any gene, even if a gene turns on when no microarray sampling takes p......ne." So more work needs to be done to increase the sensitivity of the new test. Last summer was the first time that Plaxco had high school students doing work for academic credit in his lab. "It was great," said Plaxco. "I thought they might be a distraction, but my students and post-doctoral fellows did a grea...