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UCLA researchers identify key enzyme linked to childhood blindness

...ristic of this disease is that the light sensitive rod and cone cells remain intact in the retinas of Leber patients for a long time. "This suggests that replacement of RPE65 by gene therapy should correct the blindness in these children, as was observed in mice and dogs with RPE65 mutations," Travis sa...

'Prosthetic' retinal cells let blind mice see light

... for the treatment of complete blindness caused by rod and cone degeneration," they wrote. ...

Surprise finding for stretched DNA

...le is stretched. The model consists of an elastic rod that is wrapped around its outer surface by a stif...us to DNA's sugar-phosphate backbone. The elastic rod is constructed from a material that conserves volume under stress. "As this system is stretched, t...

Study provides first look at the 'birth' of a retina cell

...'s team reports that NRL is the earliest marker of rod precursors, or cells that are fated to become rods. They achieved this unique and early view of rod development by creating a mouse model using an NRL regulatory DNA sequence to produce a protein that...

Transplanted photoreceptor precursor cells restore visual function in mice with retinal degeneration

...e University of Michigan Kellogg Eye Center to tag rod precursor cells and prepare them for transplantati...ements: the cells survive; correctly develop into rod photoreceptors; integrate and connect in sufficient numbers to neurons that ultimately carry visual ...