reuptake

Scientists discover the body's marijuana-like compounds are crucial for stress-induced pain relief

... to something like Prozac, which blocks the body's reuptake of the compound serotonin, causing it to be active longer, Hohmann said. Apparently, several parts of the brain are involved in the effect, most notably a structure in the midbrain known as the periaqueductal gray. In this region, stress causes the ...

Gene variation affects tamoxifen's benefit for breast cancer

...Effexor does not. These drugs, selective serotonin reuptake inhibitors or SSRI's, are often used to treat hot flashes, a common side effect of tamoxifen. In this current study of 256 women with breast cancer, researchers also found that women with the CYP2D6 variant were less likely to have hot flashes. Any ...

Commonly used antidepressants may also affect human immune system

..., however, whether these SSRI (selective serotonin reuptake inhibitors) drugs "including the brands Prozac, Zo...ng a T cell response." Drugs that block serotonin reuptake "likely change some of the parameters of T-cell activation, but we don't know yet if it enhances or ...

Nobelist discovers antidepressant protein in mouse brain

...he surface of receiving cells. Serotonin selective reuptake inhibitors (SSRIs), medications commonly prescribed for anxiety and depression, compensate for reduction in serotonin signaling by boosting levels and binding of serotonin to receptors. Previous studies have suggested that serotonin receptors are ess...

High dopamine transporter levels not correlated with ADHD

...or lower dopamine levels by reducing the number of reuptake proteins. This would explain the positive correlat...ansporter levels and inattention: as the number of reuptake proteins rises, the amount of dopamine would decline, leading to a higher level of inattention. This...

Adolescent but not adult hamsters are more aggressive on low dose of fluoxetine

...n adults." Fluoxetine, a selective serotonin reuptake inhibitor (SSRI), is the only medication approved to treat depression in children and adolescents. However, it has carried an FDA "black box" warning since Fall 2004 due to findings of increased risk of suicidal thoughts and behaviors in some childr...