replicon

Gene Vaccine Protects Mice Against Development Of Her2/neu Breast Cancer

... and thenpackaged the virus vector into virus-like replicon particles, referredto as “VRP-neu.?When these non-propagating particles are injected intoan animal, the vector directs the animal’s cells to make thousands ofcopies of the HER2/neu growth protein, says Lachman.In addition, the VRP-neu preferentially ...

A comprehensive response to HIV could prevent 10 million AIDS deaths in Africa by 2020

... and thenpackaged the virus vector into virus-like replicon particles, referredto as “VRP-neu.?When these non-propagating particles are injected intoan animal, the vector directs the animal’s cells to make thousands ofcopies of the HER2/neu growth protein, says Lachman.In addition, the VRP-neu preferentially ...

Hepatitis C complicated by morphine withdrawal

...rphine withdrawal enhances hepatitis C virus (HCV) replicon expression, appears in the November issue of The A...To measure HCV replication, they used a virus-like replicon that mimics the events that occur in liver cells and expression of viral RNA and proteins that HCV u...

Texas scientists discover how a hepatitis C protein promotes liver cancer

...produce proteins made by hepatitis C viruses. "The replicon experiments enabled us to identify a protein known as NS5B that attaches to the retinoblastoma protein, a critical tumor suppressor, and accelerates its breakdown," Lemon said. He continued: "The way NS5B docks with the retinoblastoma protein is bioc...

Cyclosporine inhibits hepatitis C virus in vitro

...M.D. of the University of Florida, treated the HCV replicon line, GSB1, with varying doses of Cyclosporine for 48 hours and examined the results. They found that Cyclosporine reduced HCV replication by 20 percent, compared to no reduction with Tacrolimus. Furthermore, the Cyclosporine appeared to work through...