renal

Bioartificial kidney under study at MCG

...across the country to evaluate the efficacy of the renal assist device, says Dr. Harold M. Szerlip, MCG nephrologist specializing in acute renal failure and a principal investigator on the study. "If you have renal failure in the ICU, your mort...

Next Generation Body Scanner Launched By The University Of Manchester

...ular abnormalities to the kidneys in patients with renal disease. The scanner, which has been manufactured...as clinicians specialising in oncology, stroke and renal medicine. We look forward to seeing the benefits of this exciting new development in imaging for pat...

Monkeying around to improve organ transplantation

...me that anergic T cells generated ex vivo suppress renal allograft rejection in non-human primates. This may be an approach that could be used in human transplant trials. Title: Renal allograft rejection is prevented by adoptive transfer of anergic T cells in non-human primates ...

Genetically engineered animals help in scientific research that may benefit children

...animal model of obstructive nephropathy, a type of renal disease, has given researchers new insight in the ...nd in children and is the first cause of end-stage renal disease (ESRD). According to the article, ESRD represents 16.1% of all pediatric transplantations i...

Stem cells bring fast direct improvement, without differentiation, in acute renal failure

Acute renal failure, or ARF, is as serious as it sounds. An es...- risk patients as those with diabetes, underlying renal disease, and the elderly. In the kidneys, such "insults" lead to destruction of kidney tubular and v...

Minimally Invasive Cancer Treatments Highlighted

...in women. The most common type of kidney cancer is renal cell carcinoma. Interventional radiology treatment...prospective study of MRI-guided cryoablation of 44 renal tumors shows that 96% were successfully ablated and 93% required only one treatment session. MRI mon...

Human albumin from tobacco plants

...alnutrition or dehydration, chronic infections and renal or liver illnesses. The annual consumption in Spain is about 10 tons but, at a worldwide level, the demand exceeds 500 tons. Agricultural engineer, Alicia Fernández San Millán, has developed a novel technique in Spain - plastidial transformation, in...

Marine mammals are on the frontline of failing ocean health

...le cadmium (a heavy metal associated with bone and renal disease) is higher in organs of mammals with invertebrate-based diets. "The issue is to understand how pollutants are transferred through the ocean food web to consumers, both humans and animals," says Peggy Krahn of the NOAA. "Until we underst...

New research demonstrates bone-marrow derived stem cells can reverse genetic kidney disease

...e-marrow derived stem cells can regenerate damaged renal cells in an animal model of Alport syndrome provid...ltration system and typically leading to end-stage renal disease in the patient's teens, 20s or 30s. The disease additionally causes deafness in some patient...

Hantavirus found in African wood mouse

...nd Asian hantaviruses cause hemorrhagic fever with renal syndrome (HFRS), a group of similar illnesses with symptoms including, fever, kidney failure, and bleeding. The viruses are carried by a number of rodents, including the brown rat, the striped field mouse, and the yellow-necked mouse. If left untreat...

Basic research leads to a novel cancer therapy

...Imatinib at all. Still other patients had advanced renal cell carcinoma with failed available treatment. In...pared to the placebo group. Patients with advanced renal cell carcinoma saw a shrinking of the tumour; in 26 to 37 percent of them, the tumour shrunk to at l...

Scientists tie several cancers to common 'oncogene engine'

...sarcoma, alveolar soft part sarcoma, and pediatric renal carcinoma ?are often lethal if surgery cannot completely remove them. Dana-Farber researchers are already using these new insights in clinical trials of a cancer vaccine, GVAX, that previously has produced rare but dramatic responses in some patient...

Scientists solve 30-year-old mystery of mutant mouse's kidney woes

...oking for other genetic factors that contribute to renal diseases. ...

Fatty fish protects against cancer

...eat fatty fish gain significant protection against renal cancer. At least one portion of fatty fish a week... during the period (1987-2004) reduced the risk of renal cancer by 74 per cent compared with those who never ate fatty fish. The group who ate fresh fish at ...

76 percent of workers older than 60 years of age are overweight or obese

...on between metabolic syndrome and minor degrees of renal dysfunction. Metabolic Syndrome and cardiovascular illness The metabolic syndrome has acquired increasing interest in the area of prevention. In the first place, this syndrome is associated with the development of diabetes, closely linked to ...

More kidney cancer is detected and treated early, yet death rate rises

... in the occurrence of kidney cancer (also known as renal cell carcinoma) for tumors of all sizes. But the g...re not saying that surgery for patients with small renal masses is inappropriate," Hollingsworth says. "Our findings, however, show that their increased trea...

Vaccine for brain tumors shows promising results

...tion in both metastatic melanoma (skin cancer) and renal cell carcinoma (kidney cancer). The UCSF clinical trial is a phase1/2 study designed to establish the feasibility, safety and preliminary efficacy of vaccination in patients with recurrent, high-grade glioma. The trial involves two groups of six ...

'Trojan Horse' agent halts bone metastasis in mice

...n bones such as breast, multiple myeloma, lung and renal cell. "Many tumors invade bone in the same way, so these findings suggest it may be possible to shut down this process regardless of the tumor type," says the study's lead author, Michael G. Rosenblum, Ph.D., professor in the Department of Experim...

Mutant gene causes severe kidney disease in infants

...r a severe, early-onset form of kidney disease and renal failure in children: recessive mutations in a gene...ease is severe and infants often go into end-stage renal disease within the first year of life. So, until now, most physicians believed there was no point in...

Active ingredient in common Chinese herb shown to reduce hypertension

...ers applied the 2-kidney-1-clip protocol to induce renal hypertension in male golden Syrian hamsters. The a...used to place a silver clip to constrict the right renal artery. Sham-operated hamsters and mice underwent the same procedure, except for the placement of a ...

Twin studies reveal genetic components leading to cardiac and kidney disease

...n pool study revealed the influence of heredity on renal protein (albumin) excretion. Excretion of the pro...ic pathway. Links between adrenergic activity and renal injury could lead to novel approaches to predicting, preventing, diagnosing and treating kidney dise...

UCSF brain tumor vaccine trial shows promising results

...ion for both metastatic melanoma (skin cancer) and renal cell carcinoma (kidney cancer). Reviewing the presentation at AANS, Henry Brem, MD, director of neurosurgery at the Johns Hopkins Medical Institutions, noted, “This is an encouraging study of a therapeutic cancer vaccine that targets multiple tum...

Researchers shed light on mechanism of action used by anti-cancer drug

...y been approved for the treatment of patients with renal cell cancer, the most common form of kidney cancer in adults. It was originally developed as an inhibitor of the oncogene, Raf, which is frequently mutated in numerous cancers, including leukemia. Oncogenes are typically responsible for promoting tum...

Liver cancer patients with high serum levels of hepatitis B virus face poorer outcomes

...treatment, the researchers monitored blood counts, renal and liver function and clinical signs and symptoms. They then performed statistical analysis to assess which factors might have influenced patient outcomes. The median survival of all patients was 6.83 months. Patients with high pre-treatment HBV ...