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DuoCort: New chronotherapy for adrenal insufficiency

... publishes data from its Phase I study for the rare and life threatening disease adrenal ... therapy to survive. Adrenal insufficiency is a rare disease that affects patients in their active ... for patients with adrenal insufficiency, a rare disease for which DuoCort has orphan drug ...

Activated stem cells in damaged lungs could be first step toward cancer

... proliferating cells that are derived from these rare stem cells." Stripp said this finding could be ... out with a strong chemical, naphthalene. Then the rare proliferative cells became active and grew into ... can come at a price. An acquired mutation in that rare cell or its descendants leads to clonal patches ...

NIH announces new program to develop therapeutics for rare and neglected diseases

... pipeline to produce new treatments for rare and neglected diseases. The $24 million program ... trans-NIH initiative called the Therapeutics for rare and Neglected Diseases Program, or TRND. The ... working on these illnesses. The NIH Office of rare Diseases Research will oversee the program, and ...

Predators ignore peculiar prey

... rare traits persist in a population because predators ... by the oldest and most obvious hypothesis rare form advantage arises because predators tend to overlook rare prey". ...

A big lesson from the reef

... provide us." Prof. Connolly says that the many rare species the GBR contains make the system more ... conditions change, then common species may become rare and rare species common but the system as a whole ...

Diet secrets of 'the Royals'

... element for example, common carbon-12 versus rare carbon-13. The method used in the study involves ... is made of hydrogen and oxygen, so ratios of rare hydrogen-2 (deuterium) to hydrogen-1, and of rare oxygen-18 to oxygen-16 in tail hair reflect ...

Y chromosome and surname study challenges infidelity 'myth'

... had surnames and by the sixteenth century it was rare not to have one. Dr King and Professor Jobling found that men with rare surnames such as Grewcock, Wadsworth, Ketley and ... of children born illegitimately. People with a rare surname are very likely to be related as the ...

'Fishy' clue helps establish how proteins evolve

... University of Tokyo have demonstrated how this rare amino acid and, by example, other amino acids ... publication of the journal Nature . The rare amino acid the Yale researchers studied, ... to engineering the genetic code." Pyl is so rare that it has been found in only seven organisms. ...

MUHC and McGill scientists explain genetic disease first discovered in Quebec 24 years ago

... a 24 year-old hunt for the cause of an incredibly rare genetic disorder called, cblF combined ... the vast majority of patients with this rare disease share a common mutation despite the fact ... Rosenblatt, who was the first to describe this rare genetic condition in 1985. "Vitamin B12 plays an ...

Rare corals breed their way out of trouble

... rare corals may be smarter than we thought. Faced with ... of threatened species. It is often assumed that rare coral species face higher risks of extinction ... Zoe says. "When we studied some particularly rare species of Acropora (staghorn corals), which you ...

Anti-cancer drug prevents, reverses cardiovascular damage in mouse model of premature aging disorder

... damage in a mouse model of progeria, a rare genetic disorder that causes the most dramatic ... aimed at untangling the biological roots of this rare disease may prove valuable in understanding the ... in general. "What we learn through studies of rare genetic disorders often has implications for more ...

Extinction most likely for rare trees in the Amazon rainforest

... scenarios of deforestation and road-building, but rare trees could suffer extinction rates of up to 50 ... of tropical forests is the presence of very rare tree species. Competing models of relative ... lognormal curve, yield different proportions of rare trees in the forest. Thirty years ago Stephen P. ...

Killer whales, blind bats, discriminating dolphins, mating birds

... those we cannot hear -- like the croaks made by a rare species of frog that communicates ultrasonically ... while navigating the world. There are a few rare individuals who can echolocate very well without ... that there are certain groups of more elusive and rare species that are much better represented in the ...

World's only captive hairy-nosed otter gets new home

... his capture. The natural habitat for this rare species in Cambodia is the seasonally flooded ... of flooded forests where at least two species of rare otters are known to exist, the hairy-nosed otter ... Cambodia is now a stronghold for many rare species that have been driven to extinction ...

Second genetic link to weight and obesity

... the genes known to play a role in severe - but rare - diseases are also implicated in much more ... on the normal functioning of the gene as do the rare mutations in MC4R that can cause rare examples of very serious, early onset obesity." ...

Yale study shows how rare genes have big impact on blood pressure

... Nature Genetics that they have discovered that rare genetic variants can be associated with a ... in the general population. The insight that rare mutations may collectively play a large part in ... a disease is more closely linked to common or rare mutations. Recent studies have shown that for ...

Rare genetic mutations protect against hypertension

... Institute (HHMI) researchers have found that rare mutations in three genes contribute to blood ... in the three salt handling genes cause several rare diseases that are characterized by low blood ... What's more, by identifying the role played by rare genetic mutations in governing how the kidney ...

CSHL scientists part of team that discovers role of rare gene mutations in schizophrenia

... (NIMH), have identified multiple, individually rare gene mutations in people with schizophrenia that ... schizophrenia. The results were striking. rare mutations showed up in only 5 percent of the ... percent of those with schizophrenia. The rate of rare mutation was higher still -- 20 percent -- among ...

UD's Bobev receives NSF Early Career Award for research on novel compounds of rare Earth metals

... the properties of novel compounds formed from the rare earth metals and selected semi-metallic elements, including silicon, germanium and tin. The rare earth metals are relatively less known than other ... the bottom of the periodic table. They aren't as rare as once thought. In fact, they are commonly used ...

Photo-monitoring whale sharks

... through a fine mesh of gill-rakers. Listed as a rare species, relatively little is known about whale ... identification with ecotourism to study the rare species and suggests whale shark populations in ... and conservation benefits, says Norman. As a rare and highly migratory fish, whale sharks are a big ...

Book on little-known species and conservation provides guidance to managers and others

... inventory and conservation plan for more than 300 rare species believed to be associated with old-growth ... it out. The recently published Conservation of rare or Little-Known Species, by Island Press, answers ... regarding alternative approaches to conserving rare or little-known species; the economic, legal, ...

Sequella receives US and EU orphan drug status for SQ109 for the treatment of TB

... pharmaceutical companies to develop drugs for rare diseases defined as those affecting fewer than ... and approval processes for treatment of rare diseases. For further information, please visit: ... or companies who intend to develop medicines for rare diseases (so-called 'orphan drugs'). Orphan ...

October Geology and GSA Today media highlights

... the distant past has come from studies of those rare sites at which soft tissues such as skin and ... cores. However, long lake sediment records are rare in the Arctic because ice sheets during the last ... terraina situation in the Arctic that is not as rare as it once was thoughtvaluable records of ...

Study links virus to some cases of common skin cancer

... COLUMBUS, Ohio A virus discovered last year in a rare form of skin cancer has also been found in people with the second most ... system. "Originally it was thought that this virus caused only this rare skin cancer, but our findings indicate that it is a lot more prevalent ...

Little-known protein found to be key player

... week report that a little-understood protein previously implicated in a rare genetic disorder plays an unexpected and critical role in building and ... disorder that atlastin has been linked with," Daga said. HSP is a rare genetic condition that affects fewer than one million people worldwide. ...

Bizarre walking bat has ancient heritage

... the air had an Australian ancestor 20 million years ago with the same rare ability, a new study has found. The discovery overturns a long-held held ... a result of isolation on islands. "Rather, it would seem that walking is rare in bats because it has advantages for them only in special circumstances. ...

Maternal, paternal genes' tug-of-war may last well into childhood

... CAMBRIDGE, Mass., July 28, 2009 -- An analysis of rare genetic disorders in which children lack some genes from one parent ... Haig says. Haig delved into clinical case reports on patients with four rare genetic disorders. He found evidence that children with disorders ...

Biologists rediscover endangered frog population

... Museum retracing a 1908 natural history expedition both rediscovered the rare mountain yellow-legged frog in the San Jacinto Wilderness near Idyllwild, ... Zoo's breeding program, in conjunction with its partners, began after the rare frogs were rescued from a drying creek. Anne Poopatanapong, a wildlife ...

Further gene mutations linked to autism risk

... (CHOP). The study identified 27 different genetic regions where rare copy number variations missing or extra copies of DNA segments were ... disease-free children. Besides the identification of 27 regions harboring rare variants in children with ASDs, the study also uncovered two novel genes ...

Wildlife Conservation Society supports world's first study of egg-laying mammal

... other field biologists considered "mission impossible"the first study of a rare egg-laying mammal called the long-beaked echidna. The WCS-supported ... Opiang and the data he gathered can now help us to manage and protect this rare and species." About long-beaked echidnas Echidnas are members of the ...

International Serious Adverse Events Consortium announces initial study results in its global research collaboration to identify genetic markers related to drug induced liver injury

... that can cause liver injury in a very small subset of patients, and in rare cases this may lead to acute liver failure. Although the exact mechanisms behind such rare and unpredictable DILI is unknown, research suggests a genetic ...

Study finds homicidal poisoning rising, more likely in infants and elderly

... Athens, Ga. Homicidal poisonings are rare but on the riseand infants are the most common victimsaccording to a new ... available, the rate was 0.3 per million people. "Homicidal poisoning is rare relative to a lot of other causes of death, but the numbers are trending ...

Reef boom beats doom

... can spell the total loss of the corals. However, a lucky combination of rare circumstances meant the reefs were able to achieve a spectacular recovery, ... area and moderately good water quality", said Dr Diaz-Pulido. "It is rare to see reports of reefs that bounce back from mass coral bleaching or ...

Boston College chemistry professor Udayan Mohanty receives a 2009 Guggenheim Fellowship

... Guggenheim Memorial Foundation Fellowship for his theoretical studies of rare chemical reactions. Mohanty said he was honored to be among the 180 ... models to develop a set of tools that will allow scientists to describe rare fluctuations in chemical systems. He hopes to discover chemical reaction ...

Young dinosaurs roamed together, died together

... Mongolia. The Sudden sudden death of the herd in a mud trap provides a rare snapshot of social behavior. Composed entirely of juveniles of a single ... and Lucile Packard Foundation. "Finding a mired herd is exceedingly rare among living animals," said Varricchio, an assistant professor of ...

Cellular discovery may lead to targeted treatment for rare form of anemia

... have identified the specific biological mechanisms believed to lead to a rare and incurable blood disease known as Diamond Blackfan anemia (DBA). ... Conference in New York, which concludes Monday, March 16. DBA is a rare blood disorder characterized by the bone marrow's failure to produce red ...

2 genes influence social behavior, visual-spatial performance in people with Williams syndrome

... Studies have traced the role of two genes,GTF2I and GTF2IRD, in a rare genetic disorder known as Williams Syndrome. Their results, published ... genes are missing from one of two copies of chromosome 7). There also are rare cases of individuals who retain one or more genes that most people with ...

New research shows how gene function drives natural selection in important class of genetic elements

... how retrotransposons work. But the research also shows there are rare episodes of positive selection and even adaption to a host genome when ... an intriguing glimpse into how these twin evolutionary pressures can, in rare cases, "sign an armistice." ...

Princeton-led team finds secret ingredient for the health of tropical rainforests

... tropical rainforests, a vital part of the Earth's ecosystem, rely on the rare trace element molybdenum to capture the nitrogen fertilizer needed to ... trace amounts of vitamins are essential for human health, this exceedingly rare trace metal is indispensable for the vital function of tropical ...

New genes present drug targets for managing cholesterol and glucose levels

... LDL by about 15-30 milligrams per deciliter. Finally, there are extremely rare changes in the same gene that affect fewer than 1 in 1000 people but can ... genetic variants were also related to the risk of gallstones and certain rare forms of diabetes. "Each of these genes is a potentially interesting ...
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(Date:9/18/2014)... their entire lives nestling in the protective tentacles of ... they sometimes travel hundreds of kilometres across the open ... fish has been predicted, this is the first time ... populations has been observed. , Dr Steve Simpson, Senior ... University of Exeter, and colleagues from the Australian Research ...
(Date:9/17/2014)... UCLA atmospheric scientists were instrumental in the creation of ... tool to classify the fire threat potential of the ... a spark into an inferno. The index was introduced ... with UCLA and San Diego Gas and Electric. , ... to "extreme" that will be used to help fire ...
(Date:9/17/2014)... engineering professor and his doctoral student have designed a ... water collected from fog and dew., The device could ... deserts around the globe., Cheng Luo, professor in the ... candidate in the same College of Engineering department, published ... of ACS, (American Chemical Society) Applied Materials ...
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