pump

Tiny particles could solve billion-dollar problem

... develop a device that would include a cylindrical pump containing a catalytic membrane of the gold-pallad...would be placed down existing wells where it would pump water through continuously, breaking TCE into non-toxic components. Cost is the primary hurdle to c...

Taking Aim With Nanoparticle PEBBLEs

...ancer cells get immune to chemotherapy drugs ?they pump the drugs back out," Kopelman said. Cancer cells can't do that to PEBBLEs, though, because PEBBLEs are already on the outside. Another advantage: the "killer oxygen" that PEBBLEs deliver to cancer cells is too unstable to wander off and damage health...

Implanted Devices Detect High-Risk Heart Failure Patients

...on marked by the inability of the heart muscles to pump enough oxygen and nutrients in the blood to the body's tissues. Also known as congestive heart failure, its many causes include infections of the heart, coronary artery disease, high blood pressure, previous heart attacks and valve problems. An estim...

Stem Cell Research Shows Potential for Replacing Tissue Damaged in Heart Attacks

...the myocardium tissue, or heat muscles, that helps pump the chambers of the heart. “After a patient has a heart attack, significant numbers of these cardiac myocytes die, and the damaged heart muscle is replaced by scar tissue that isn’t able to contract and help the heart beat. This problem is one of t...

Growth in biomass could put US on road to energy independence

Relief from soaring prices at the gas pump could come in the form of corncobs, cornstalks, switchgrass and other types of biomass, according to a joint feasibility study for the departments of Agriculture and Energy. The recently completed Oak Ridge National Laboratory report outlines a nati...

Human Cells Filmed Instantly Messaging for First Time

Relief from soaring prices at the gas pump could come in the form of corncobs, cornstalks, switchgrass and other types of biomass, according to a joint feasibility study for the departments of Agriculture and Energy. The recently completed Oak Ridge National Laboratory report outlines a nati...

Canada approves marijuana-based pain spray

...ivex works Sativex is administered through a spray pump under the tongue or on the inside of the cheek, providing reliable, self-administered pain relief. The spray formulation allows for more flexible dosing than an oral tablet, well suited to the variable nature of neuropathic pain experienced by people...

Researchers make headway in mystery of migraines

...ll, and drawing potassium from outside, the sodium pump maintains a gradient of potassium, which is critic... air conditioner in the heat of summer, the sodium pump is a massive energy hog, consuming around 30% of the energy produced by the cell in order to perform...

Newly Discovered Role for Heart Response Enzyme May Yield Better Heart Failure Therapy

...conditions are lost, rendering the heart unable to pump enough blood to meet the needs of the body's other organs," said cardiologist and geneticist Howard Rockman, M.D., of Duke. "If we could prevent this loss of heart receptors, we might improve heart function in patients with heart failure." The enzym...

Software might revolutionize glucose monitoring in critically ill patients

...ucose levels and recommends theappropriate insulin pump rate and the time at which the next bloodsample should be taken, and indicates situations in which a physicianneeds to be notified. In many ICUs, nurses currently monitor glucose levels manually ten to twelve times a day and record their measurements...

Implantable pumps extend lives of patients too sick for transplant

...at pumps blood throughout the body ?is too weak to pump enough blood to nourish the body's tissues. LVADs ...ally at the site in the side of the body where the pump is connected to an external power source and computer. "We already had a lot of data on the device ...

Fruit fly's beating heart helps identify human heart disease genes

...at has greatly enlarged and therefore is unable to pump blood efficiently. The moving images revealed that fly heart looked and acted just like a human heart with the same condition. "The difficulty in performing studies to find specific genes that cause disease in humans is that you need large families ...

For one Stanford doctor, the beat goes on during open-heart surgery

...machine, aka "the pump," for bypass surgeries. The pump lets the surgeon stop the heart by keeping blood circulating throughout the body, which keeps the patient alive, while the doctor sews on new vessels. It's easier for surgeons to perform because they have a stable target. The heart is not moving. In...

Stem cell study for patients with heart attack damage seeks to regenerate heart muscle

...ged muscle inhibits the heart's overall ability to pump blood, leading to heart failure," said Rush principal investigator cardiologist Dr. Gary Schaer, head of the Rush Cardiac Catheterization Laboratory. Rush is the only center in Illinois participating in the trial. There are 15 other sites nationwide...

Forsyth scientists gain greater understanding of how embryos differentiate left from right

...rong natural voltage gradients and pH changes. The pump that normally acidifies subcellular compartments w...ional component of this novel mechanism ?a protein pump that generates voltage and pH gradients. For the first time, we have a glimpse of how three differen...

Drug resistance may travel same path as quorum sensing

...ance is not just to one drug, but many because the pump is now increased and many different drugs will be pumped out. "It compounds the problem," said Zechiedrich. Her findings are a step toward understanding the mystery surrounding drug resistance, she said. In her work, she found that two of these "pu...

Mice with glowing hearts shed light on how hearts develop

...l development. "We knew that the heart starts to pump at around 9.5 days," said Kotlikoff. By day 10.5, there are only two chambers (rather than four chambers in an adult mammal): an atrium on top and a ventricle on the bottom. A delay in beats between the two gives the atrium time to contract and push ...

Molecular force field helps cancer cells defend against attack

...ltures of human breast cancer. Breast cancers that pump out high volumes of FAK and VEGFR-3 are more aggressive tumors, Cance said. The scientists were able to block FAK from binding with VEGFR-3 by introducing a different protein that stopped cancer cells from dividing and caused them to die but spared n...

Chocolate, wine, spicy foods may be OK for heartburn, Stanford study finds

...they recommend. These days that's usually a proton pump inhibitor, which reduces the amount of acid secreted in the stomach. Gerson said that for the most part, medication alone is adequate to treat the symptoms of heartburn. "The main reason they probably have heartburn is that their sphincter muscle is...

Spinal cord bridge bypasses injury to restore mobility

...into the new nerve growth, Houle implanted a small pump that delivered a steady dose of chondroitinase to a new incision site near C5 where the researchers hoped to reconnect the other end of the bridge to the spinal cord, but also prevent further scarring. They also primed the newly re-grown axons for ra...

Corn waste potentially more than ethanol

...ortfolio," says Logan. "Electricity can be used to pump water uphill for later use, directly run light, heat and equipment or electrolyze water to create hydrogen." The Penn State researcher and colleagues have also used microbial fuel cells and wastewater to produce hydrogen gas directly. ...

Heart has enough oxygen to survive hypothermia, CPR crucial

... cardiac output (the volume of blood the heart can pump per minute), or with oxygen transport to the cells," Tveita said. In particular, the research team wanted to know if insufficient circulation leads to inadequate oxygen supply to the heart cells, which in turn leads to heart failure. The researcher...

Study shows pine bark naturally decreases severe chronic venous insufficiency

...nous insufficiency is caused when leg veins cannot pump enough blood back into the heart. When people are not active, blood pools in their leg veins, legs and ankles can become swollen," said Peter Rohdewald, Ph.D. and researcher of the study. "Eventually, some of the valves cannot hold the weight of exc...

Researcher gives hard thoughts on soft inheritance

... DNA methylation. "The idea was : If you pump these pregnant moms up with these dietary supplements, you might be able to skew the DNA methylation patterns, and thus skew the way the mice come out at the end of the day, and it works,'" Richards says. "In this particular instance that says what ...

New study reveals structure of E. coli multidrug transporter protein

...s cyanide m-chlorophenyl hydrazone, a known efflux pump inhibitor, before it reaches the cell cytoplasm. This binding is likely facilitated by hydrophobic interactions within the internal cavity of EmrD. The researchers speculate that cyanide m-chlorophenyl hydrazone is either expelled from the bacterial ...

Climate change has surprising effect on endangered naked carp

...idney functions also decline. The sodium/potassium pump (Na+/K+-ATPase), which is a protein critical for cellular function, operated at only 30 percent of its capacity in lake-water fish compared to river-water fish. Ammonia-N secretion by the kidneys declines by a surprising 70 percent, and urine flow...

Cigarette smoking impedes tendon-to-bone healing

...d from nicotine exposure rather than from having a pump implanted beneath the skin. In the rats that got nicotine, the pumps maintained nicotine levels in the bloodstream about equivalent to smoking a pack to a pack and a half of cigarettes per day. "So these would have been heavy smokers," Galatz says...

Cardiologist's 'living chip' changes science of disease monitoring

..., a wireless defibrillator/pacemaker or an insulin pump ?to take action to correct a detected abnormality. The device would communicate with the living chip in real time, making adjustments as a direct result of the chip's ability to detect changes. The company's molecular biology team is being led by B...

PNAS study reveals why organs fail following massive trauma

... normal transition, the innate system continues to pump out toxic chemicals (cytokines) and molecules (free radicals) that tear at organs until they fail. The goal of the current study was to identify the few genes and proteins that play a central role in T-cell mediated immune and organ failure. Given ...

Chemical tests of cell growth enter third dimension

...ide effects on the body. "The trick is to use one pump for everything, and control the fluid distribution though all the channels," Yang said. While he has worked out an initial design, he would like to join with a commercial microfluidics manufacturer to develop the technology further. The university i...

Key to lung cancer chemo resistance revealed

...toxifies cells by directing proteins to absorb and pump out pollutants and chemicals. The NRF2 gene makes a "trigger" protein which starts the production of other proteins and enzymes that sweep the cell clear of toxins. To halt the detox process, proteins manufactured by KEAP1 bind to the NRF2 triggers...

Fast test for low blood flow in dogs detects early heart trouble

...m per minute, for five minutes. When forced to pump faster, healthy heart tissue and surrounding blood vessels will adapt, while unhealthy, blocked ones will slow blood flow. These changes are not usually perceptible to the human eye from the scanned images but can be detected and quantified with CT ...

Researchers identify new weapon to fight deadly bacterial sepsis

...y." The drastic drop in the heart's ability to pump blood is dangerous in itself, the researcher conti... enzyme's activity restored the heart's ability to pump blood normally and allowed mice injected with otherwise lethal levels of LPS to survive. Other ex...

Mechanical 'artificial hearts' can remove need for heart transplant by returning heart to normal

...ake the blood to a mechanical pump. The mechanical pump then pumps the oxygen rich blood into another tube which is connected to the aorta. Once blood is in the aorta, it can be transported to the rest of the body. Patients were treated with drugs which encourage reverse remodelling of the heart, preve...

New approach could lower antibiotic requirements by 50 times

...-resistant to antibiotics because they have efflux pump mechanisms that enable them to throw out antibiotics. A pore in the cell wall would obviously cancel the efflux effect,' Hagens explains. Pseudomonas bacteria cause pneumonia and are a common cause of hospital-acquired infections. Experiments in ...

Breathing easy: When it comes to oxygen, a bug's life is full of it

...rough holes in their bodies known as spiracles and pump the oxygen through a system of increasingly tiny t...piracles. Insects also use different mechanisms to pump the oxygen to the tissues. This system is much more efficient than the system that vertebrates ev...

Cholera pathogen reveals how bacteria generate energy to live

...he source of energy; the other uses this energy to pump ions out of the cell," Barquera said. How the two ...ard methods of determining structure. Since an ion pump needs to carry ions from one side of the bacterial membrane to the other, the enzyme has to reach al...

Wheat can fatally starve insect predators

...s and the base of the plant where the insects feed pump out nutrients favored by the insect. If this happens then even the weak, avirulent larvae on the same leaf have a chance to survive. The researchers discovered that Hessian fly larvae reprogramming of resistant plant cells only occurs at site...

Bisexual fruit flies show new role for neurochemical

...n the brain. Called xCT transporter proteins, they pump glutamate out of glia cells. "When we mutate the protein, we get less ambient extracellular glutamate, more glutamate receptors, and so a stronger transfer of messages at synapses," Featherstone said. The gene mutation also made the flies bisexua...

Study warns deep-sea mining may pose serious threat to fragile marine ecosystems

...y operated underwater mine cutters and a hydraulic pump system to transfer roughly two million tons of ore per year to the surface. These strips would be located approximately 500 meters to two kilometres from the active vents, but Halfar argues that the cutting and pumping process will disgorge considera...

Percutaneous aortic valve replacement safe, successful in high-risk patients

...he procedure, the patients were placed on a bypass pump for an average of 30?0 minutes to minimize blood flow through the aorta and ease placement of the replacement valve. All 17 patients survived the procedure. One patient died 5 days later from stroke. Five additional patients died after discharge ...

Machine preservation may promote more organ sharing

...eserving the kidneys of deceased older donors on a pump ?as opposed to the conventional method of storing ...ege of Surgeons. In addition, Stratta said, the pump can be used to project the kidney’s initial function ?allowing for more appropriate matching of dono...

Catching cancer's spread by watching hemoglobin

...the hemoglobin after the excitation. Sometimes the pump laser is off and there is no two-photon absorption. By subtracting the signal from the "off" state from the "on" state (when two-photon absorption occurs), the researchers remove unwanted scattered light from the data and can get high-quality signals...

In nature, proteins sweep up nanoparticles

...aste particles into the environment, bacteria also pump proteins into the environment. These proteins then sweep the sulfide nanoparticles out of solution into a ball. Scientists don’t why this occurs. Perhaps it’s a serendipitous accident. Proteins and peptides could be released by bacteria after they...

Now, self-healing materials can mimic human skin, healing again and again

...tudent and lead author of the paper. “While we can pump more healing agent into the network, ‘scar tissue’ builds up in the coating and prevents the healing agent from reaching the catalyst.” In the current system, the healing process stops after seven healing cycles. This limitation might be overcome b...