progesterone

Female sex hormones play a vital role in defense against sexually transmitted diseases

...es as well show that women who use Depo-provera, a progesterone based injectable contraceptive, have particularly ...osing them to the herpes virus. Both estradiol and progesterone are natural hormones found in the body. The estradiol-treated mice were protected 100 percent, wher...

Controlling protein diversity

...n previous studies that hormones like estrogen and progesterone can change the amounts of proteins made by their target genes. When hormone binds to receptors inside the cells, they are activated to seek out target genes. They then recruit the coactivators ?in this case CAPERá and CAPERâ. These coactivators not o...

Mother birds increase progesterone to hatch females

...esence of higher-than-normal levels of the hormone progesterone during the first meiosis -- the cell division that... preovulatory follicle." To test the influence of progesterone on the sex ratio of offspring, Correa, along with Elizabeth Adkins-Regan, professor of neurobiology ...

By creating molecular bridge, scientists change function of a protein

...ise fashion, Zhao said. They used testosterone and progesterone to build the bridge. The receptor was gradually altered to accept one steroid, then another, until accepting the desired one -- corticosterone, a potent glucocoticoid. In total, Zhao and Chen did four rounds of random mutagenesis and screened about ...

Going To Extremes To Improve Human Health

...ainting than men, he also studies how estrogen and progesterone influence blood pressure regulation. Minson is the winner of a 2005 American Physiology Society's Outstanding Young Investigator Award (his second since 2000) and a similar national honor conferred in 2000 by the American College of Sports Medicine....

Breast stem cells have features similar to 'basal' tumors

...st stem cell expresses receptors for oestrogen and progesterone and the marker 'Her2', since these help define the...m cell in mice is 'triple negative' for oestrogen, progesterone and Her2receptors but does express certain 'basal cell' markers. These characteristics also define t...

The influence of the menstrual cycle on the female brain

...esticles), which interact with estrogen receptors, progesterone or androgens. 7. Luteinizing hormone (LH) is a...lly" higher the brain activity.) Estrogens and progesterone are not just sex hormones that influence ovulation and reproduction; they also affect a large number...

Molecular signature may identify cisplatin-sensitive breast tumors

...nt of breast tumors that have neither estrogen nor progesterone receptors and also do not overexpress HER2. Since these so-called "triple-negative" tumors are treatable with neither Herceptin nor antiestrogen drugs, the prognosis for patients with the tumors has been poor. Triple-negative tumors are the most ...

Selective marker found to indicate aggressive form of breast cancer

...t molecular targets such as the estrogen receptor, progesterone receptor and Her2. This not only makes positive d...f breast cancer tumors lacking estrogen receptors, progesterone receptors and Her2, DiRenzo and his colleagues found extremely high amounts of nestin in 14 of 16 tu...

Brain's reward circuit activity ebbs and flows with a woman's hormonal cycle

...by estrogen, compared to a phase when estrogen and progesterone are present. "These first pictures of sex hormon...ase; activity in these areas was also triggered by progesterone levels while women were anticipating rewards during the post-ovulatory phase. Activity patterns that...