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The evolution of gene regulation

... Even microbes are governed by the principle of supply and demand at least at the genetic ... analyses that another indeed opposing principle also comes into play: "wear-and-tear". According ... repressor when needed." The "use-it-or-lose-it" principle was proposed to explain this, which demands the ...

New gas sensors for monitoring carbon dioxide sinks

... time. The patented gas sensor is based on the principle of diffusion, according to which certain gases ... the underground injection of carbon dioxide. The principle can also be used in liquids, so the probe is also ... adjustable threshold value is exceeded." The same principle can be used for monitoring dangerous substances ...

Biochemists reveal details of mysterious bacterial microcompartments

... in the desert and many viral structures. "This principle of closing a structure by combining a large ... and soccer ball manufacturers." That principle is also understood by microcompartments, in which ... reported in the journal Science an underlying principle that governs the assembly of microcompartments: ...

New method separates cancer cells from normal cells

... The demonstrated device, which takes advantage of a physical principle called ratcheting, is a very tiny system of channels for cell locomotion. ... online by the journal Nature Physics . "We have demonstrated a principle that offers an unconventional way to fight metastasis, a very different ...

NIH grants $122 million in Institutional Development Awards

... $17.4 million New Mexico IDeA Networks of Biomedical Research Excellence principle Investigator: Jeffrey B. Arterburn, Ph.D. University of Alaska ... (Newark) $17.4 million IDeA Network for Biomedical Research Excellence principle Investigator: David S. Weir, Ph.D. University of Idaho (Moscow) $16.5 ...

150 years of Darwin's landmark book spawns international conference

... The conferenceDarwin's Legacy: Natural Selection as an Organizing principle in Sciencewill bring together scientists from a variety of disciplines (or a variant thereof) as a guiding principle in their research. Among those already confirmed to talk about how Darwin ...

UC Riverside rice geneticist receives high honor from US Department of Agriculture

... Initiative Discovery Award. The three scientists are, or have been, principle investigators on grants the USDA has awarded them for rice research. ... Sciences , is the lead recipient of the USDA award. She has been the principle investigator on three USDA-funded projects that led to the identification ...

Swamping bad cells with good in ALS animal models helps sustain breathing

... that has a long history of research-resistant biology - finding a proof of principle in animal models is significant. This week, Johns Hopkins researchers ... diseases. So on a more basic level, the study adds clout to the principle - in live animals - that excitotoxicity is a major bad guy in ALS and that ...

Spiders who eat together, stay together: UBC research

... elevation. "The size of organisms tends to be constrained by a scaling principle scientists call 'surface to volume ratio,'" says Leticia Avils, lead ... is how nature keeps the sizes of various species in check." The same principle may apply to social groups. The surface area of the three-dimensional webs ...

Eliminating germline lengthens fly lifespan, Brown study shows

... that create eggs and sperm. The work suggests a provocative general principle at work: Signals from reproductive tissue directly control lifespan and ... If so, wed know that reproductive control of lifespan was a general principle in biology. In their experiments, Flatt and Tatar over-activated a gene ...

New window opens on the secret life of microbes

... Nowhere is the principle of "strength in numbers" more apparent than in the collective power of ... responses to environmental stresses. Such methods are based on the principle that "microbes grow faster and so respond to environmental stresses more ...

St. Jude identifies the specific cell that causes eye cancer, disproving long-held theory

... gives rise to the eye cancer retinoblastoma, disproving a long-standing principle of nerve growth and development. The finding suggests for the first time ... the retina called horizontal interneurons. This disproves the scientific principle that fully formed, mature nerves cannot multiply like young, immature ...

Nanoparticle-delivered 'suicide' genes slowed ovarian tumor growth

... in targeted therapy. "In oncology we have been studying ways to kill tumors for a long time, but much of this has run up against the real estate principle of location, location, location," he said. "In other words, an effective therapy is not effective if it cannot get to the target." Sausville said ...

University has grand designs to build a house of straw

... be monitored for a year for its insulating properties, humidity levels, air tightness and sound insulation qualities. Dr Katharine Beadle, the principle researcher on the project, explained: "We're putting sensors into the walls to monitor temperature and humidity levels, and using technology to ...

Researchers develop 'brain-reading' methods

... at the back of the brain where information is processed and then conveyed towards the frontal regions associated with awareness. "It's the same principle experienced during a car accident. The car accident actually happens tens of a milliseconds before you are aware you have actually been hit," ...

Promising new treatment for Alzheimer's suggested based on Hebrew University research

... rate than in those who have the normal gene. The result is that the carriers maintain higher levels of this neurotransmitter, so they should in principle be protected from Alzheimer's disease, in which acetylcholine levels decrease. Indeed, these carriers tend to develop the disease later than ...

New way to make sensors that detect toxic chemicals

... systems (made in a similar fashion to computer chips), with a goal of identifying known toxic substances. The design works on the same general principle as another, much more familiar sensor. "The human nose coordinates signals from hundreds of thousands of sensory neurons to identify chemicals," ...

Finding the constant in bacterial communication

... millions of different kinds of bacteria with their own ways of sensing the world around them, Duke University bioengineers believe they have found a principle common to all of them. The researchers said that a more complete understanding of communication between cells and bacteria is essential to the ...

GUMC discovery highlights new direction for drug discovery

... of treated tumors compared to untreated tumors. Toretsky says that while the agent needs to be "optimized," these results serve as a proof of principle that inhibiting protein-protein interaction can work as a novel therapeutic that will target only cancer cells. "We may be able to use this ...

NSF provides $3.4 million to study climatically important Agulhas Current

... current meters will measure the rest of the water column. All current meters are acoustic, with no moving parts, measuring velocity using the principle of Doppler shift, whereby the frequency of a sound wave changes as it reflects off a moving particle in the ocean. Offshore recirculations and ...

Research explores interactions between nanomaterials, biological systems

... such as suntan lotions, for instance, may be coated with a water-repelling polymer to reduce direct contact with human skin. An extension of this principle uses polymers and detergents to decrease cellular uptake. However, there is the potential that when the coating wears off, the material may become ...

Crustacean shell with polyester creates mixed-fiber material for nerve repair

... and add polyester to make clothing that's soft, breathable and wrinkle free. Now researchers at the University of Washington are using the same principle for biomedical applications. Mixing chitosan, found in the shells of crabs and shrimp, with an industrial polyester creates a promising new material ...

Newly discovered reactions from an old drug may lead to new antibiotics

... of Health and the Florida Department of Health funded the research, which was conducted at UCF during the past three years. "It's the proof of principle that we are excited about," Self said from his research lab at UCF. "No one has ever tried this approach, and it could potentially be a source for ...

Combined stem cell-gene therapy approach cures human genetic disease in vitro

... led by researchers at the Salk Institute for Biological Studies, has catapulted the field of regenerative medicine significantly forward, proving in principle that a human genetic disease can be cured using a combination of gene therapy and induced pluripotent stem (iPS) cell technology. The study, ...

A quicker, cheaper SARS virus detector -- one easily customizable for other targets

... in the liquid, it will bind to these antibodies, immediately creating a sharply measurable jump in current through the nanowire. The basic principle of nanotube and nanowire biosensors for protein detection was first demonstrated in 2001, but the new design by a team headed by Zhongwu Chou and ...

Resilin springs simplify the control of crustacean limb movements

... movements by moving a joint with just one muscle that operates against a spring made of the almost perfect elastic substance called resilin. This principle is analysed and illustrated by striking photographs and high-speed video footage, published in the open access journal BMC Biology , of the ...

Saved by junk DNA

... junk DNA allows fast shifts in gene activity, which may allow organisms to tune the activity of genes to match changing environments -a vital principle for survival in the endless evolutionary race. Evolution in test tubes To further test their theory, the researchers conducted a complex ...

Capturing the birth of a synapse

... of formal publication in the open-access journal Neural Development . "We've caught two neuronal cells in the act of forming a synapse," said principle investigator Philip Washbourne, professor of biology at the University of Oregon. He describes the cell-adhesion neuroligin proteins on the membranes ...

Wings that waggle could cut aircraft emissions by 20 percent

... uses tiny air powered jets which redirect the air, making it flow sideways back and forth over the wing. The jets work by the Helmholtz resonance principle - when air is forced into a cavity the pressure increases, which forces air out and sucks it back in again, causing an oscillation the same ...

Researchers gain genome-wide insights into patterns of the world's human population structures

... . The lead authors were Shameek Biswas and Dr. Laura B. Scheinfeldt, both of the UW Department of Genome Sciences. A statistical method called principle component analysis allows researchers to look through a thick, voluminous fog of genetic data and see significant variations. The UW researchers ...

Association for Molecular Pathology joins ACLU to challenge gene patents

... to do so," said Jan A. Nowak, MD, PhD, the president of AMP. "We have done this for a number of reasons, the most compelling of which is that the principle being argued in the case is consistent with our desire to support public policies that we believe are in the best interests of our profession and the ...

Researchers find snippet of RNA that helps make individuals remarkably alike

... Professor of Molecular Biology in the Weinberg College of Arts and Sciences at Northwestern. Carthew led the research. "This design is similar to the principle that engineers use to design safety features into products." There are hundreds of different types of microRNAs in animals. Their function is to ...

Fertilization intensifies competition for light and endangers plant diversity

... the exact mechanisms that lead to the loss of biodiversity from grasslands following fertilization. Competition Following the 'Winner-takes-all' principle Different plant species profit from nutrient addition to different degrees with some species growing much faster than before. Consequently, some ...

Unifying the animate and the inanimate designs of nature

... of animals or trees," Bejan said. "That's too bad, because design features are everywhere in nature. The constructal law can be seen as a universal principle of evolution, which applies in many fields, from physics to economics." He describes the law as an animated movie, where one screen is replaced by ...

Conference tackles technology needed to address climate change

... for Learning & Discovery, McMaster University WEBSITE: www.cctc2009.ca CCTC 2009 is hosted by the Engineering Institute of Canada as the principle organizer in partnership with nine of its member societies: IEEE, Canadian Society for Civil Engineering, Canadian Dam Association, Canadian Nuclear ...

UC Davis launches 'One Health' care for wild mountain gorillas and human neighbors

... "The concept of 'One Health' - that human, animal and environmental health are inextricably linked and should be considered holistically - is a core principle of the UC Davis Wildlife Health Center," said wildlife veterinarian and center assistant director Kirsten Gilardi, who will lead the Mountain Gorilla ...

A cure for honey bee colony collapse?

... parasite that could be responsible, we can look for signs of infection and treat any infected colonies before the infection spreads" said Dr Higes, principle researcher. This finding could help prevent the continual decline in honey bee population which has recently been seen in Europe and the USA. ...

Alzheimer cell death in Zebrafish: Demise of neurons observed live for the first time

... that can stop the extensive cell death, and thereby stop dementia in patients," says Haass. "The first findings have already shown that we can in principle use drugs to block at least some of the disease-related processes in the zebrafish." Around one million people in Germany suffer from Alzheimer's ...

Novel lung cancer vaccine shows promise in fighting early-stage lung cancer

... Thirty-five percent of non-small-cell lung cancers have this protein which also is present in some melanomas and head and neck cancers. "The principle is that you can possibly teach a patient's immune system to eliminate cancer cells that express certain proteins such as the MAGE-A3 protein," said ...

Mollusks taste memories to build shells

... pattern. "Our real contribution is not reproducing the patterns, but showing that the nervous system can do it with one equation based on the principle discovered by Ernst Mach in the 1860s," Oster said. Striped shells are the easiest to explain with this neural network model. A pigment-secreting ...
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(Date:8/29/2014)... surprising discoveries about the body,s initial responses to ... team found that specialized cells in the intestine ... invasion and are the source of gut inflammation ... , Though aimed at the presence of ... that provides a barrier to protect the body ...
(Date:8/29/2014)... ANTONIO (Aug. 29, 2014) Scientists at the Barshop ... School of Medicine at the UT Health Science Center ... in the tissues of the longest-lived rodent, the naked ... in the cells of naked mole rats protects and ... for damaged and obsolete proteins. , The factor also ...
(Date:8/29/2014)... known about what genetic changes transform wild animals into ... whom is a University of Montana assistant professor, has ... development of the brain and the nervous system were ... Aug. 28 in Science and gives answers ... http://www.sciencemag.org/ ., The domestication of animals and plants, a ...
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