pregnancy

BRCA1 causes ovarian cancer through indirect, biochemical route

... cycles through their life without interruption by pregnancy or oral contraceptive use are at highest risk for developing sporadic ovarian cancer," Dubeau explains. "So we had some clues that the cells that control the menstrual cycle-the ovarian granulosa cells-have an influence on ovarian cancer." But how? ...

Bone Density Recovers After Teens Stop Injected Contraceptive

...gainst the potential consequences of an unintended pregnancy that could result from using a less effective method.?/p> On November 17, 2004, the U.S. Food and Drug Administration issued a “black box warning?for DMPA, stating that prolonged use of the drug may result in significant loss of bone density, tha...

PET/MRI scans may help unravel mechanisms of prenatal drug damage

... transferred between a mother and her fetus during pregnancy may help us unravel the mechanisms of the drug's damaging effects on unborn children," said SNM member Helene Benveniste, M.D., Ph.D., chair of Brookhaven's medical department in Upton, N.Y., and lead author of the paper, "Maternal and Fetal 11C-Coca...

Harmful chemicals may reprogram gene response to estrogen

...creased risk for reproductive tract abnormalities, pregnancy complications such as ectopic pregnancies and preterm deliveries, infertility, and a rare vaginal and cervical cancer called clear-cell adenocarcinoma. Other research conducted by NIEHS scientists indicates that women exposed to DES in utero have a h...

First frozen egg baby born in Canada

...he patient went through an uncomplicated full-term pregnancy and straightforward delivery," says Dr. William Buckett, the MUHC physician who looked after the mother during the pregnancy. The parents, who requested anonymity, described the procedure as easy and uncomplicated. The father stated: "Words cannot de...

Technique may allow cancer patients to freeze eggs, preserving fertility before starting treatment

...one thing; thawing them safely so they can lead to pregnancy is the challenge. In the past, efforts to freeze a woman's eggs, or oocytes, have not worked well because the cells are large. When the egg is thawed, ice crystals cause damage that prevents the egg from being fertilized. U-M researchers looked beyo...

Research shows smoking adds a decade to reproductive age of IVF patients

...to 20% for non-smokers." The miscarriage rate per pregnancy was also significantly higher for women who smoked, with around 21% losing their babies compared with around 16% of non-smokers. Overweight women also fared badly with a 33% lower chance of a live birth from their first treatment cycle. As with smok...

New miniaturised chip dramatically reduces time taken for DNA analysis

...r cost and availability will be similar to that of pregnancy test kits found in pharmacies. The researchers Sa...d and the product to become as widely available as pregnancy test kits we can buy at the local pharmacy". Electrochemical genosensors vs DNA chips Identifying ...

Major new UNC-based drinking water study suggests pregnancy fears may be overstated

...3,132 women in the three areas who were planning a pregnancy or who had been pregnant for fewer than 12 weeks. ...h factors as age, education, alcohol use and prior pregnancy histories, analyzed the data to see what effects the byproduct compounds might have had on pregnancy...

Antiretroviral Therapy May Prevent HIV Transmission From Breastfeeding Mothers To Infants

...apine, lamivudine, and zidovudine beginning during pregnancy or postpartum, and 25 women from an earlier time period with comparable HIV disease, who did not receive antiretroviral therapy because it was unavailable to them at the time they were breastfeeding. The results indicated that antiretroviral therapy...

Circulating stem cells play small role in lung repair

...cytes in female lungs might result from an earlier pregnancy with a male fetus cannot be ruled out, Zander said. However, the association between the number of those cells found in the lung tissue with damage from rejection makes that unlikely. There was no sign of fusion between the bone marrow-derived cells...

Candida albicans Genome Fully Annotated

...cytes in female lungs might result from an earlier pregnancy with a male fetus cannot be ruled out, Zander said. However, the association between the number of those cells found in the lung tissue with damage from rejection makes that unlikely. There was no sign of fusion between the bone marrow-derived cells...

Any exposure to tobacco smoke during pregnancy is risky

...suggests that exposure to second-hand smoke during pregnancy can be just as detrimental to a developing fetus a... "This analysis shows not only that smoking during pregnancy causes genetic damage in the developing fetus that can be detected at birth, but also that passive ?...

One hit of crystal meth causes birth defects

.... "We've known for a while that meth abuse during pregnancy is associated with low birth weight, cleft palates...elop. "People usually think the last trimester of pregnancy is when developing brain function is most susceptible to damage, but in this case the brain is also ...

Scripps research scientists identify infertility molecule

...ore pronounced for mature women who are attempting pregnancy because a woman's egg production decreases with age, especially after the age of 35. Often, women will undergo treatments for infertility that range from taking hormones to stimulate ovulation to having their eggs harvested by doctors, fertilized by...

Drug Offers Alternative to Surgical Treatment After Miscarriage

...atient basis.?/p> The study authors wrote that pregnancy failure, or miscarriage, occurs in 15 percent of p...w years, physicians have used misoprostol to treat pregnancy failure, and some researchers have conducted a few small studies of the drug’s effectiveness in trea...

Sleeping Sickness Epidemic Spreading in Uganda

...atient basis.?/p> The study authors wrote that pregnancy failure, or miscarriage, occurs in 15 percent of p...w years, physicians have used misoprostol to treat pregnancy failure, and some researchers have conducted a few small studies of the drug’s effectiveness in trea...

Researchers seek to discover what really happens when a virus enters the body

...nclude the development of a fetus during a woman's pregnancy and the production of milk by lactating women. So the question remains: do we really know what a body's host cell does when a virus infects it? Bell and Duca's collaboration is an attempt to profile the host-virus system using the electrical engi...

OHSU research shows vitamin C counteracts some negative impacts of smoking on unborn babies

...s born to mothers who continue to smoke throughout pregnancy despite physician warnings. The research is publis...rcent of pregnant mothers continue to smoke during pregnancy -- this translates to about a half a million American women a year. Reflecting the highly addictive ...

Pregnant women at higher risk for HIV, Uganda study finds

...n of this potential risk of HIV acquisition during pregnancy and promote safe sex or sexual abstinence where fe...at reported a greater risk of acquiring HIV during pregnancy than after delivery. However, neither study accounted for risk factors that contribute to HIV risk. ...

Hide and seek: Researchers discover a new way for infectious bacteria to enter cells

...s, listeriosis can be fatal, and infections during pregnancy can lead to miscarriage, stillbirth, premature delivery, or infection of the newborn. The research was conducted by Pascale Cossart, a Howard Hughes Medical Institute international research scholar, and her colleague Esteban Veiga at the Institut P...

New technique rapidly detects illness-causing bacteria

...ult shows up as a red line on a strip, much like a pregnancy test. Newly designed software gives researchers a ..., it turns the strip visibly red, much like with a pregnancy test. The entire process takes only 35 minutes, while traditional gene amplification techniques may...

Gene discovery sheds light on causes of rare disease, cancer

...s, listeriosis can be fatal, and infections during pregnancy can lead to miscarriage, stillbirth, premature delivery, or infection of the newborn. The research was conducted by Pascale Cossart, a Howard Hughes Medical Institute international research scholar, and her colleague Esteban Veiga at the Institut P...

Defect in gene causes 'neuralgic amyotrophy'

...uch as vaccination, infection, operation, and even pregnancy or childbirth. By virtue of their genetic predisposition, carriers of the hereditary form of HNA run greater risk of having an attack. Its re-occurrence, and the fact that the disease is provoked by environmental factors, make this disorder unique in...

Israeli scientists successfully transplant frozen-thawed ovaries in sheep

...nsplant might interfere with natural conception so pregnancy may require IVF techniques, but we have been able to demonstrate long-term intact organ cryopreservation with restored function following thawing and transplantation, in a large animal for around 36 months post-transplantation," said Dr Arav. "This a...

Lactose intolerance linked to ancestral environment

...ally in hot climates. Nausea and vomiting early in pregnancy also may protect women and their embryos from food-borne pathogens and other toxins." A Darwinian medicinal view complements traditional medicine, Sherman said, because if researchers can better understand why a symptom occurs, such as a fever, runn...

Scientists closer to new cancer detection method

...d like to see this assay become as convenient as a pregnancy test," said Chaoyong James Yang, a chemistry doctoral student in the Tan group and the first author of the paper. "Put the probe inside a few drops of body fluid or blood and a color change would be an indication of the existence of a cancer biomarke...

Studies on human genome variation provide insight into disease

...ight into human biology and disease. Predicting pregnancy success Successful human reproduction and the maintenance of early pregnancy are dependent on a cluster of genes on chromosome 19 called the Luteinizing Hormone/Chorionic Gonad...

Housecat-sized Siberian tiger cubs get collared

...ight into human biology and disease. Predicting pregnancy success Successful human reproduction and the maintenance of early pregnancy are dependent on a cluster of genes on chromosome 19 called the Luteinizing Hormone/Chorionic Gonad...

Chernobyl: The true scale of the accident

...f any effect on the number of stillbirths, adverse pregnancy outcomes, delivery complications or overall health of children. A modest but steady increase in reported congenital malformations in both contaminated and uncontaminated areas of Belarus appears related to better reporting, not radiation. Did the tr...

Cells from amniotic fluid used to tissue-engineer a new trachea

..., DC. Amniotic fluid is easily collected during pregnancy and contains unspecialized cells, known as mesenchymal stem cells, that can make many of the tissues needed to perform repairs, Fauza says. While tracheal defects are rare, they're life-threatening: babies born with incomplete, malformed or missing...

Womb needed for proper brain development

...opment. When a fetus's brain is developing during pregnancy in utero, very little patterned sensory stimulation reaches the brain, she explained. The eyelids are closed, the infant is bathed in fluid and minimal sounds are perceived. In contrast, once the premature infant is born, he is necessarily bombarded...

Study finds that nutritionally enhanced rice reduces iron deficiency

...ear causes more than 60,000 maternal deaths during pregnancy and childbirth. Recent statistics from the Micronutrients Initiative of Canada and the United Nations Children's Fund indicate that more than half of the developing world's children between 6 months and 2 years of age are iron-deficient during the c...

Birth defects: 8 million annually worldwide

...ionals to maximize the chances of having a healthy pregnancy and a healthy baby. Improvement Is Possible, March of Dimes Says Although poorer nations may lack resources for these recommended programs and their health services are already severely stretched, the March of Dimes report says major improvement...

Ultrasounds show mothers' drinking shrinks fetal brain

...ise in maternal-fetal health. Alcohol use during pregnancy is a leading preventable cause of birth defects an...ene with women at high-risk for an alcohol-exposed pregnancy is prior to pregnancy," says Louise Floyd of the Fetal Alcohol Prevention Team. "What we are hoping ...

Hyena mothers give their cubs a helpful dose of hormones

...t alpha females had higher androgen levels late in pregnancy when compared to the subordinate, pregnant females in the pack. Consequently, the cubs of the alpha females were more aggressive and exhibited more sexual play, characteristics that elevate the chances for life-success in both sexes. In hyena packs,...

Absence of critical protein linked to infertility

...r protein C/EBPb must be present in the uterus for pregnancy to occur. The study appears online this week at th...od supply and forms the placenta. For a successful pregnancy to occur, stromal cells of the uterus must be transformed into decidual cells, which secrete nutrien...

US woman gives birth to baby from world's first frozen donor egg bank

... to the waiting woman who wishes to experience the pregnancy and birth of her baby. "We're very happy this tec...rey Boldt, PhD, Scientific Director for CEI. The pregnancy rates with donor eggs are beginning to show success rates equivalent to pregnancy rates using eggs b...

First link of oral bacteria and preterm birth found in human

... prior to 30 weeks than those that happen later in pregnancy and can result in babies born with many health challenges and who struggle to thrive at their low-birth weights. According to 2003 statistics from the March of Dimes ( http://www.marchofdimes.com/prematurity/15341_10734.asp ), hospital charges for n...

Prenatal nicotine exposure reduces breathing response of newborns...

... prior to 30 weeks than those that happen later in pregnancy and can result in babies born with many health challenges and who struggle to thrive at their low-birth weights. According to 2003 statistics from the March of Dimes ( http://www.marchofdimes.com/prematurity/15341_10734.asp ), hospital charges for n...

One-third of adults with diabetes still don't know they have it

...r higher have had diabetes that developed during pregnancy (gestational diabetes) or have given birth to a baby weighing more than 9 pounds have polycystic ovary syndrome, a metabolic disorder that affects the female reproductive system have acanthosis nigricans (dark, thickened skin around neck or armpi...

Study finds that a woman's chances of having twins can be modified by diet

...ngs of this study suggest that women contemplating pregnancy might consider substituting meat and dairy products with other protein sources, especially in countries that allow growth hormone administration to cattle," said Dr. Steinman. Dr. Steinman has been studying factors that cause or contribute to twinn...

Nicotine exposure during development leads to hearing problems

...tists know that children of women who smoke during pregnancy can develop hearing-related cognitive deficits. Fo... precisely what aspect of smoking is so harmful in pregnancy when it comes to cognitive hearing deficits," Metherate said. "Most women who smoke find it difficul...

New egg freezing technique offers hope to hundreds of women

...ival rate for the freeze-thawed oocytes and a high pregnancy rate of nearly 42% after the oocytes had been fertilised and implanted in the women. This pregnancy rate is practically the same as the rate we can achieve in our clinic using fresh oocytes." The Cry...

Smooth sailing: 'cruise ship virus' tackled by UH, Baylor College of Medicine

...d a diagnostic tool that mimics something like the pregnancy test in speed and ease of use, we could create a platform for rapid detection of this virus and other pathogens." The tool Ruchhoeft and Willson are building will rely on the disease protein/antibody relationship that occurs in the human body. A...

Schepens scientists are first to discover angiogenesis switch inside blood vessel cells

...ood flow after injury, prepares a woman's body for pregnancy and increases circulation in a damaged heart. But, it can also nourish cancer tumors and damage delicate retinal tissues when uncontrolled. The angiogenic process is triggered by what the body perceives as a need for additional blood flow. In the ...

Dominant meerkats render rivals infertile

...n pregnant themselves, reducing subordinate female pregnancy rates will reduce the threat of infanticide. Dr Andrew Young, Department of Zoology, University of Cambridge, who led the research said, "The findings are particularly exciting as the consensus emerging from prior research on cooperative species wa...

US infant mortality rate fails to improve

...men and their doctors what they can do?even before pregnancy ?to help give babies their full nine months of ges...in containing folic acid prior to and during early pregnancy to reduce the risk of serious birth defects; abstain from drinking alcohol during pregnancy and see ...

Researchers report technique for freezing and preserving genetically enhanced pig embryos

...se many embryos are needed to produce a successful pregnancy in surrogate female pigs, this new procedure will enable workers to collect an adequate number of altered embryos and store them until they can be transplanted to a surrogate. Swine embryos have been difficult to freeze and preserve because of their...

Hair samples show babies can be exposed to 'crystal meth' while in the womb

...caine. . Drug abuse increases complications of pregnancy and triples the likelihood of serious medical problems among the babies born, say the authors....

Study challenges myth that sex late in pregnancy hastens birth

...ng in sexual intercourse during the final weeks of pregnancy can hasten labor and delivery. In fact, just the ...ledged that women who are more comfortable late in pregnancy may be more likely to engage in sexual activity, and that women who experience abdominal discomfort ...

New angiogenesis finding may help fight cancer growth

...els form when wounds heal and during menstruation, pregnancy and fetal development. But impaired blood-vessel d...ly, and since adults need angiogenesis only during pregnancy and to heal wounds, blocking angiogenesis could be a promising way to halt tumor growth. Also in Jun...

Study suggests evolutionary link between diet, brain size in orangutans

... at greater risk for nutritional stress because of pregnancy and lactation and their smaller homes ranges. "The general scenario supported by these results, then, is that an increase in the frequency of uncontrollable periods of low energy intake in one part of the orangutan's geographic range selected for a...

Planning ahead: Having the healthiest baby possible

Women who improve their own health before pregnancy have a better chance of delivering a robust, healt...ry about a pregnant woman's health only during her pregnancy or a child's health only after his or her birth, because many of the factors that contribute to the ...

Emergency contraception fails to halt abortions

...ception does not have a notable effect on rates of pregnancy and abortion, according to an editorial in this we...hreefold, but had no measurable effect on rates of pregnancy or abortion. Most women who did not use their supply, said they did not realise they had put the...

Down syndrome: It's not just the age factor

...gnificantly higher in older mothers in their first pregnancy than in older mothers who had already had children. Only late first pregnancies were more likely to produce a Down Syndrome baby, not late second or third pregnancies. In addition, the larger the gap between pregnancies, the higher the rates of Do...

Researchers discover that sheep need retroviruses for reproduction

...occurring endogenous retroviruses are required for pregnancy in sheep. In particular, a class of endogenous ...or enJSRVs, are critical during the early phase of pregnancy when the placenta begins to develop. Retroviruses, such as human immunodeficiency virus or HIV, ar...

Scientists design simple dipstick test for cocaine, other drugs

... user-friendly kits similar to those used for home pregnancy tests. "Building upon our earlier work with lead (Pb) sensors, we constructed colorimetric sensors that are based on the lateral flow separation of aptamer-linked nanostructures," said Yi Lu, a chemistry professor at the U. of I., and a researcher a...

Molecules in blood foretell development of preeclampsia

...els also rose in the 33rd through the 36th week of pregnancy for women who later developed gestational hyperten...levels of both soluble endoglin and sFlt1 early in pregnancy might be especially helpful in predicting the later development of preeclampsia. Detecting high lev...

Heavy smoking cuts women's chance of pregnancy -- even with donated oocytes

...ugal and Spain, comes as a result of comparing the pregnancy rates between non-heavy smokers and heavy smokers,... "The non-heavy smokers had a significantly higher pregnancy rate, with over half becoming pregnant (52.2%), compared with just over a third (34.1%) of the heavy...