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Chemists create 'Superbowl' molecule; May lead to better health
...ed and refined by chemists for their wide range of potential uses, including drug delivery, chemical synthesis ...ks solubility in water, which could compromise its potential medical applications, the researcher says. Superbowl molecules also have the potential to be toxic. ...Viral DNA sequence a possible trigger for breast cancer
...ransforms them. This study puts the spotlight on a potential new mechanism for virus-induced breast cell transformation, which has largely been attributed to the integration of viral DNA into locations that trigger the expression of host cancer-causing genes. An intriguing wrinkle to this study is the previous...Association of herpesvirus with lung disorder questioned
...provide scientists with another perspective on the potential causes of primary pulmonary hypertension," Dr. Katano said. "Further studies are required to clarify the possible association of human herpesvirus 8 with this disease." ...A new mechanism of regulating RNA degradation
...nt attention in recent years, and one that has the potential to produce a new set of tools for physicians to use to fight disease. Most of the gene-control tools researchers have collected thus far involve the first step in gene expression, in which DNA is copied into RNA transcripts. However, recent discover...FDA Approves Human Hookworm Vaccine for Phase I Safety Trials
...nt attention in recent years, and one that has the potential to produce a new set of tools for physicians to use to fight disease. Most of the gene-control tools researchers have collected thus far involve the first step in gene expression, in which DNA is copied into RNA transcripts. However, recent discover...Spleen may be source of versatile stem cells
...ing, members of thesame team now report that these potential adult stem cells produce aprotein previously believed to be present only during the embryonicdevelopment of mammals.The finding both supports the existence of these splenic stem cells andalso suggests they may be able to produce an even greater varie...UCSB scientists probe sea floor venting to gain understanding of early life on Earth
...oms on abyssal hill fault scarps, thus providing a potential food source for ridge flank biota, and an opportunity for researchers to sample the biosphere below the sea floor." The sides of abyssal hills are fault escarpments (or scarps) created by vertical uplift of the seafloor during many events of fault s...University of Manchester makes made-to-measure skin and bones a reality using inkjet printers
... says Professor Derby.Professor Derby believes the potential for this technology is huge:"You could print the scaffolding to create an organ in a day," he says....Enzyme, lost in most mammals, is shown to protect against UV-induced skin cancer
...n cancer. Moreover, CPDs and 6-4PPs haveparticular potential to cause lasting damage to mammalian cells becausephotolyases ?a class of enzymes capable of efficiently repairing theselesions ?have apparently been lost from placental mammals over thecourse of evolution.Thus, most mammals, including humans, can on...Novel technology detects human DNA mutations
... the broad applicability of nanotechnology and its potential to markedly advance the state-of-the-art in nucleic acid and proteomic research anddiagnostics."The analysis of whole human genomic DNA is extraordinarily complex asit requires sifting through the more than one billion base pairs of DNA to find a par...Poor prenatal nutrition permanently damages function of insulin-producing cells in the pancreas
...ason why infants with low birth weight have a high potential of developing type 2 diabetes later in life. In studies of mice, the researchers found that poor prenatal nutrition impairs the pancreas's ability to later secrete enough insulin in response to blood glucose. "The bottom line is that if you don't ha...Neuronal 'traffic jam' marks early Alzheimer's disease
...phasized that any application of these findings to potential diagnostic tests or new therapies remains speculative at this time. "However, if tracers could be developed that would reflect transport function, there could be imaging methods that might be helpful for diagnosis," he said. "And, if these findings c...Current human embryonic stem cell lines contaminated UCSD/Salk team finds
...ed with a non-human molecule thatcompromises their potential therapeutic use in human subjects,according to res...an antibodies, and thus renderingthem useless as a potential therapeutic tool in humans."It's an important safety issue because this opens up the idea thatmetabo...Drug That 'Tags' Decision-making Areas Of The Brain May Aid
...f these receptors over time, Nifrolidine couldbe a potential marker for early diagnosis of Alzheimer’s disease,...n.“Imaging of nicotine receptors also gives us the potential to study whysome people are more addicted to nicotine than others,?Mukherjee said.Additional informa...Genome of deadly amoeba shows surprising complexity, evidence of lateral gene transfer
...antially different from human enzymes, making them potential targets of inhibitors that could form the basis of new drug therapies," says TIGR President Claire M. Fraser, who supervised the Institute's role in the project. E. histolytica is a voracious predator of bacteria and shares a close relationship in t...Anti-bacterial additive widespread in U.S. waterways
...half lifeof 1.5 years in aquatic sediments. Do the potential benefits ofantimicrobial products outweigh their known environmental and humanhealth risks? This is a scientifically complex question consumers,knowingly or unknowingly, answer to everyday in the checkout line ofthe grocery store," said Dr. Halden....Newly-discovered class of genes determines ?and restricts ?stem cell fate
...en identified in many types of organs and may be a potential reservoir for tissue regeneration. A fundamental understanding of the molecular programs that regulate stem-cell differentiation is necessary for harnessing this potential. ### This work was supported by grants from the National Institutes of Healt...Scientists Replicate Hepatitis C Virus in Laboratory
...e life cycle and biology of this virus and to test potential antiviral compounds, which may lead to new therapies for the liver disease that results from infection with HCV. Scientists at the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), one of the National Institutes of Health (NIH...Research advances quest for HIV-1 vaccine
...tures of 4E10 recognition of HIV-1 helps to define potential immunogens able to elicit 4E10-like antibodies. This is an excellent example of the tremendous potential for accelerating HIV vaccine design when scientists from multidisciplinary laboratories come togethe...Study Demonstrates Gene Expression Microarrays are Comparable and Reproducible
...ormed by individual institutions.Evaluation of the potential clinical use of microarrays may requirelarger studies carried out in multiple locations and would necessitatethat microarray data produced in different laboratories be combined foranalysis. Even if all procedures and equipment were the same, smalldif...Inexpensive, mass-produced genes core of synthetic biology advances at UH
...ms that regulatebiological systems. There are many potential biochemical and biomedicalapplications.?Most immed...her colleagues have developed a technologywith the potential to make complete functioning organisms that canproduce energy, neutralize toxins and make drugs and ...Study Links Ebola Outbreaks To Animal Carcasses
...then, the network alerted health authorities about potential human outbreaks weeks before they occurred. "The signs of potential outbreaks often occur in remote areas, where roads are barely usable and communications limited," ad...Combination therapy boosts effectiveness of telomere-directed cancer cell death
...ed for the onset of telomere crisis and reduce the potential riskof acquired drug resistance, " writes Dr. Seimiya.Hiroyuki Seimiya, Yukiko Muramatsu, Tomokazu Ohishi, and TakashiTsuruo: "Tankyrase 1 as a target for telomere-directed molecular cancertherapeutics"....GATA: a graphic alignment tool for comparative sequence analysis
...ed for the onset of telomere crisis and reduce the potential riskof acquired drug resistance, " writes Dr. Seimiya.Hiroyuki Seimiya, Yukiko Muramatsu, Tomokazu Ohishi, and TakashiTsuruo: "Tankyrase 1 as a target for telomere-directed molecular cancertherapeutics"....U-M scientist to talk about tissue engineering at AAAS
...neering, Krebsbach plans to talk at AAAS about the potential for combining seemingly unrelated therapies to imp... bone growth in these patients, and Krebsbach sees potential to use it for similar gains in tissue engineering new bone. Bone morphogenetic proteins help cells ...Scientists seek answers on what activates deadly anthrax spores
...Claiborne, Ph.D., the principal investigator. "The potential importance of such a germination control mechanism in anthrax is clear, as spore germination and outgrowth are fundamental to proliferation." Claiborne, co-director of Wake Forest's Center for Structural Biology, added, "Basic understanding of the r...Emory Eye Center Implants Its First Retinal Chips In Patients With Retinitis Pigmentosa
... PhD. "This clinical trial will help evaluate the potential of Optobionics' ASR® device to provide improved functional vision or to at least slow down the progressive vision loss" says Dr. Schuchard, principal investigator for the project. "There are very few vision rehabilitative options for patients with re...Researchers reveal the infectious impact of salmon farms on wild salmon
...ting properties ?a cyclical event establishing the potential for re-infections up and down the coast. As the ab... to be very careful and conservative ?but there is potential for a major impact on the survivorship of the migrating salmon," says Lewis. "The next step is to t...Molecular machine may lead to new drugs to combat human diseases
...f tissues in the oral cavity. This makes introns a potential target for therapeutics against these diseases by using a strategy called targeted trans-splicing in which introns are manipulated to cut out malfunctioning genes. Introns' unique capability of cutting and pasting apparently has been conserved since...Novel Therapy Tested in Mice Could Chase Away Cat Allergies
...t were not allergic to cats. The molecule has the potential to prevent allergic reactions long after injections cease, Dr. Saxon says. However, further research and clinical testing would be required before it might be used in humans. He also is interested in applying this approach to develop a preventive tre...Yale Scientists Find MicroRNA Regulates Ras Cancer Gene
...wever, are relatively accessible for inhalation of potential gene therapy agents. "While this is not likely to cure the cancer," said Slack, "after diagnosis, gene therapy with let-7 may be a way to alleviate or slow it down." This work arose from Slack's basic research in the department of molecular, cellula...New imaging method gives early indication if brain cancer therapy is effective, U-M study shows
...to the chemotherapy or radiation therapy. This has potential to spare patients from weeks of a grueling treatment regimen that's not working and gives doctors the opportunity to switch patients early on to a therapy that may be more effective. Results of the study appear the week of March 28 in the early onli...Gene variations explain drug dose required to control seizures
...g's variable affects on patient metabolism and its potential neurologic side effects. The team identified genes considered to be obvious candidates underlying patients' drug response, based on their known roles in the metabolism or transport of one or both anti-epileptic drugs. In 425 epileptic patients takin...Muscle-targeted gene therapy reverses rare muscular dystrophy in mice
...st that such an approach should be considered as a potential gene therapy strategy for Pompe disease patients, ...large amount of the enzyme. "Gene therapy has the potential to reverse the course of the disease with a single treatment," Koeberl said. The researchers delive...Enzyme shown to help protect genomic stability
...rotecting the telomeric regions of the genome from potential destabilizing molecular events. The enzyme helps to keep the genome structurally closed, unavailable for transcription and possibly protected from dangerous genetic recombinations with other regions of the genome. A report on the research, which was ...Purdue proves concept of using nano-materials for drug discovery
...l membranes function on chips in order to test the potential effectiveness of new drugs to treat diseases. Membranes, which surround cells and regulate the movement of molecules into and out of the cells, contain a variety of proteins, some of which are directly responsible for cancer's ability to resist anti-...Scientists rid stem cell culture of key animal cells
...ved "feeder" cells, long thought to be a source of potential contamination for the therapeutically promising ce... already contaminated with an animal molecule. The potential threat of animal pathogens tainting human stem cell lines poses a problem for the safe clinical use ...Critical role in programmed cell death identified
...e more players we know that are involved, the more potential targets we have for therapeutics," Conradt said. During development, for example, many neurons are built, but after birth, more than half are eliminated in the central nervous system in mammals: "It's a common safeguard, to ensure that neurons talk t...ASU researchers finds novel chemistry at work to provide parrot's vibrant red colors
...ew world of color communication in parrots and the potential physiological and biochemical roles of the new molecules we found in our work." Details of the work are in a paper, "Distribution of unique red feather pigments in parrots," by McGraw and Mary Nogare, a parrot fancier from Snoqualmie, Wash., publish...Genetically modified natural killer immune cells attack, kill leukemia cells
...od sample, we made it practical to consider them a potential treatment against many different types of cancer,"...them specifically effective against ALL cells." A potential clinical application for the technology developed in this study is in leukemia patients who are trea...UCSD researchers maintain stem cells without contaminated animal feeder layers
...the generation and culture of human stem cells for potential clinical applications is timely, given the recent report of 17 newly derived stem cell lines available for non-federal research. The findings here may facilitate the derivation of new human embryonic stem cell lines without the use of animal or human...Transport System Smuggles Medicines Into Brain
...ew world of color communication in parrots and the potential physiological and biochemical roles of the new molecules we found in our work." Details of the work are in a paper, "Distribution of unique red feather pigments in parrots," by McGraw and Mary Nogare, a parrot fancier from Snoqualmie, Wash., publish...Probing The Promise And Perils Of Nanoparticles
... them, but at the same time, understand what their potential downsides might be." Banaszak Holl and graduate students Pascale Leroueil and Seungpyo Hong will discuss their research at the 229th national meeting of the American Chemical Society in San Diego March 13-17. In collaboration with other researchers ...Open microfluidic and nanofluidic systems
...addition, such integrated labs-on-a-chip have many potential applications in biomedicine and bioengineering. In the context of biomedicine, for example, they could provide fast and detailed analysis of blood samples in the physician's office without the need to wait several days before the sample has been retu...Nanogen Issued Patent for Electronic Microarray With Memory
..." circuitry and overall system costs. The electric potential is controlled at each of the NanoChip's 400 test sites to move and concentrate DNA or RNA, providing accuracy, speed and flexibility for developing molecular diagnostic tests. Storing critical voltage information allows for precise control of the bio...Scientists identify genetic pathways essential to RNA interference
...i is exquisitely specific, which gives it enormous potential for therapeutic application," says Gary Ruvkun, Ph...pathways, which was totally unexpected, suggests a potential connection between RNAi and the control of cell division in cancer." The researchers note that bett...Researchers add new tool to tumor-treatment arsenal
A new study demonstrates the potential effectiveness of treating tumors by combining agents that damage DNA with a drug that sensitizes cancer cells to these agents. The research, led by George Thomas, PhD, professor at the University of Cincinnati's (UC) Genome Research Institute, and H...Alcohol's effects on gene expression in the central nervous system
.... "For researchers, microarray technology has the potential of studying the genetic and biological bases of alcohol's rewarding effects, sensitivity to the effects of alcohol, development of tolerance to the effects of alcohol, development of alcohol dependence, and alcohol withdrawal severity," he said. "For...New SARS Protein Linked To Important Cell Doorway
As public health officials in China brace for a potential resurgence in SARS (Sudden Acute Respiratory Syndrome) in connection with Chinese New Year on February 9, researchers at Washington University in St. Louis have published insights into a new protein that could be an important contributor to the SARS ...MSI releases 'moleculizer' - a new approach to simulation of intracellular biochemical networks
...ns as they are needed, as opposed to generatingall potential complexes and reactions all at once, a task that r...dy realcellular systems, where the huge numbers of potential species andreaction channels makes things very difficult."Computer simulations can be powerful tools...NC State scientist finds soft tissue in T. rex bones
.... If further studies confirm this, we may have the potential to learn more not only about the dinosaurs themselves, but also about how and why they were preserved in the first place." The research was funded by NC State, the N.C. Museum of Natural Sciences and the National Science Foundation. "Soft-Tissue Ve...Circles Of DNA Might Help Predict Success Of Stem Cell Transplantation
...irst demonstration that high levels of sjTREC in a potential stem cell recipient can predict that their thymus will successfully reconstitute their T cell population using donated stem cells," said Xiaohua Chen, Ph.D., first author of the Blood article. "This kind of information should help physicians improve ...UCLA scientists transform HIV into cancer-seeking missile
...lls reside," Chen said. "This approach offers many potential applications for controlling cancer and other diseases." "We may be able to boost immune-system surveillance at tumor sites, identify cancer cells' exact location and kill them before they cause damage," he added. "Beyond cancer, it may be possible ...Beyond lithium for bipolar disorder
...g in the brain and of the orphan receptor GPR88 as potential new targets in bipolar disorder." Philip E. Brandish, Ming Su, Daniel J. Holder, Paul Hodor, John Szumiloski, Robert R. Kleinhanz, Jaime E. Forbes, Mollie E. McWhorter, Sven J. Duenwald, Mark L. Parrish, Sang Na, Yuan Liu, Robert L. Phillips, John J...Newly Discovered Compound Blocks Known Cancer-Causing Protein
...hensive Cancer Center scientists have discovered a potential new drug that inhibits destructive cell signals th...ounds available for screening promising drugs with potential to fight cancer and other diseases. Using automated robotics, the facility provides the kind of drug...Simple drug has the potential to save many lives threatened by malaria
...severe malaria before they reach hospital, has the potential to save many lives, say researchers in this week's...al treatment close to home to reduce delay has the potential to save many lives, they conclude. http://press.psprings.co.uk/bmj/february/ppr334.pdf">You ca...Study of genomic DNA leads to new advances in cancer diagnostics
...ave identified a method of assessing the malignant potential of cells based on the sensitivity of cellular DNA ...utilized several practical methods in their study, potential exists for future diagnostic applications. The cell smear assay, which is similar to methods commonl...Research Using Mouse Models Reveals A Novel Key Player In The Initiation Of Colon Cancer
...into other mesenchymal genetic modifiers, and into potential therapeutic approaches that affect the signaling between the two cell layers. ......icine and healthcare. Optical technology has huge potential for novel developments in the bio-medical field an...ns and should find wide use. Since it also has the potential to assist in the cellular delivery of other bio-molecules, we are now looking at other cell types to......ng influenza viruses and to reduce the impact of a potential flu pandemic." ...Other ContentsgraingraingraingraingraingrainpollenpollenpollenpollentailtailtailtailtailpolyacrylamidepolyacrylamidepolyacrylamidepolyacrylamidepolyadenylationpolyadenylationpolyadenylationantibodiesantibodiesantibodiesantibodiesantibodiesantibodiesantibodiesantibodiesantibodiespolycistronicpolyclonalpolyclonalpolyclonalpolyclonalOther TagsChallengesChallengesChallengesFishingUrateUrateUrateOther Tagspair 2pair 3pair 4pair 5pair 6pair 7brief 2brief 3brief 4brief 5brief 6brief 7tracked 2tracked 3tracked 4educational 2
(Date:5/16/2008)...16, 2008 New data show that CAPHOSOL ( www.caphos...es painful oral mucositis (OM) and improves qualit...apy and radiation therapy. These data will be rep...an oral podium presentation and one tomorrow as a ... Oncology Nursing Society (ONS). These data confir...
(Date:5/16/2008)... maintaining germ-free homes for their children ha...adoption of anti-bacterial soaps and cleaning agen... soaps now have come under scrutiny by the EPA and...oncerns. , Two closely related antimicrobials,...the debacle. Whereas triclosan (TCS) has long capt...
(Date:5/15/2008)...lobal climate change has long been a concern for e... policy issue, the problem of excessive reactive n...a growing circle of environmental scientists who s...t and negatively alters local and global ecosystem...papers by leading environmental scientists bring t...
(Date:5/15/2008)...ving found that whether bacteria stick to surfaces...IT engineers have created ultrathin films made of ...and other surfaces to control microbe accumulation... provide a valuable layer of protection for the he... of hospital-acquired infections, which take the l...
Breaking Biology News(10 mins):CAPHOSOL relieves oral mucositis and improves quality-of-life in cancer patients 2CAPHOSOL relieves oral mucositis and improves quality-of-life in cancer patients 3CAPHOSOL relieves oral mucositis and improves quality-of-life in cancer patients 4New study links fate of personal care products to environmental pollution and human health concerns 2New study links fate of personal care products to environmental pollution and human health concerns 3Addressing the 'nitrogen cascade' 2Addressing the 'nitrogen cascade' 3MIT crafts bacteria-resistant films 2MIT crafts bacteria-resistant films 3Genta Announces Licensing Agreement for Worldwide Development and Commercialization of a Leading Oral Taxane Tesetaxel 13769 1Genta Announces Licensing Agreement for Worldwide Development and Commercialization of a Leading Oral Taxane Tesetaxel 13769 2Genta Announces Licensing Agreement for Worldwide Development and Commercialization of a Leading Oral Taxane Tesetaxel 13769 3Genta Announces Licensing Agreement for Worldwide Development and Commercialization of a Leading Oral Taxane Tesetaxel 13769 4Synthetic peptoids hold forth promise for new antibiotics 13766 1Synthetic peptoids hold forth promise for new antibiotics 13766 2Allergic response tied to lipid molecules in cell membrane 13763 1Allergic response tied to lipid molecules in cell membrane 13763 2Even in Middle Age Starting to Drink May Lower Heart Risks 13761 1Even in Middle Age Starting to Drink May Lower Heart Risks 13761 2Even in Middle Age Starting to Drink May Lower Heart Risks 13761 3(Date:5/16/2008)...o Save Vital Services for Frail Seniors and People...wswire-USNewswire/ -- Thousands of,homecare worker...warzenegger,s proposed cuts to hours of service, w...ornia,s most vulnerable workers and the,people the...these vital,services for seniors and people with d...
(Date:5/16/2008)...sents Urban Health Institute with 10,000 Sensual O...rg at Playboy Mansion Fundraiser, LOS ANGELES, Ma...ip-hop,and R & B artist J Kwon known best for his ...ll be presenting the Urban Health Institute (UHI) ... over $50,000. The donation is,being made to promo...
(Date:5/16/2008)...docs determine who would benefit most from chemo a... 16 (HealthDay News) -- A panel of 15 genes may he...mall cell lung cancer will experience a recurrence...y, a new study shows. , By extension, the same... less aggressive forms of the cancer who would be ...
(Date:5/16/2008)...TON, May 16 /PRNewswire-USNewswire/ -- As tropical...e Irrawaddy delta, survivors of,Cyclone Nargis are... Many,survivors still need assistance, as exposure... an increasingly dire situation., "The people liv...,recover from this disaster and get back on their ...
Breaking Medicine News(10 mins):Health News:Homecare Workers Outraged by Proposed Cuts, Wage Reductions 2Health News:Everybody in the Club Scream O! 2Health News:Gene Signature May Predict Recurrence of Lung Cancer 2Health News:Gene Signature May Predict Recurrence of Lung Cancer 3Health News:Myanmar Cyclone Survivors Face New Challenges 2| Copyright © 2003-2008 Bio-Medicine. All rights reserved. ABOUT | CONTACT US | DISCLAIMER | PRIVACY POLICY | TERMS AND CONDITIONS |  |