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pore in Biological News

August 2009 Geology and GSA Today media highlights

... over the lower one on a cushion of high-pressure pore water trapped in sediments thrust beneath the ... specific interest here, iron isotopes in sediment pore fluids may be a unique tracer of bacterial ... a different iron isotopic fingerprint in the pore fluids compared with previous studies on the ...

Iron isotopes as a tool in oceanography

... energy. This leads to the enrichment of iron in pore fluids and bottom waters. However the ubiquity of ... specific interest here, iron isotopes in sediment pore fluids may be a unique tracer of sediment ... fill this gap be measuring iron isotopes in pore fluids from both the Eel River shelf on the ...

First tri-continuous mesoporous Silica complex structure developed in Singapore

... release. Therefore, the ability to tailor the pore structure of mesoporous material is of ... to create three interwoven but independent pore channel systems along with a unique nano-fiber ... about tailoring mesoporous materials with unique pore structures ...

Mitochondria could be a target for therapeutic strategy for Alzheimer's disease patients

... to the mitochondrial permeability transition pore (mPTP), an opening that leads to cell death for ... Mitochondrial permeability transition pore causes mitochondrial swelling, outer membrane ... of the mitochondrial permeability transition pore (mPTP), leading to cell death. Up until now, ...

Livermore researchers use carbon nanotubes for molecular transport

... more permeable than other membranes with the same pore sizes. Yet, just like conventional membranes, ... and other particles due to a combination of small pore size and pore charge effects. "While carbon nanotube ...

Media highlights for February in Biophysical Journal

... for Polymer Translocation Pulled through a Narrow pore appears in Volume 94, Issue 5, of the Biophysical ... for Polymer Translocation Pulled through a Narrow pore When polymeric molecules squeeze through a nanometer-sized pore in membranes, in a process known as ...

Carnegie Mellon team makes sequestration recommendations

... CO2 for geologic sequestration; governing access to and use of pore space for geologic sequestration; and managing liability and long-term ... Expand the federal UIC program to address conflicting uses of pore space during permitting; creating new federal legislation that would limit ...

Explosive growth of life on Earth fueled by early greening of planet

... areas, infiltrated into coastal ground waters and mixed with marine pore fluids. During sea level drops, these coastal mixing zones are dragged ... Knauth said. "Vast areas of limestone can form in these mixed pore fluids." All of which points to an environmental trigger of the ...

How mitochondria get their membranes bent

... into elongated cavities (cristae). The narrow shape of the entrance or pore to the cristae ('crista junction') allows separation of the intracristal ... cytochrome c is released into the cytosol. Thus, understanding of how the pore diameter and the shape of the inner membrane are regulated on a molecular ...

NIST issues first reference material for tissue engineering

... 3-D tissue scaffolds have a number of physical requirements. Porosity or pore size is one key factor. The pores in the scaffold must be large enough to ... and 69 percent (450 micrometers). These span the common range of pore sizes typically required for tissue engineering applications. The ...

January GEOLOGY media highlights

... ice-particle-water-air mixture generated a basal zone of high internal pore pressure. This effect is particularly strong when a thick, high-density ... Vp/Vs increase observed before the mid-October earthquakes is related to a pore pressure increase on fluid-filled cracks in the volume around the fault. ...

Genetic mutation causes familial susceptibility for degenerative brain disease

... surface of what's known as the nuclear pore. It helps the nuclear pore bring proteins into and out of the nucleus, regulates critical steps of ... our unexpected finding that a missense mutation in part of the nuclear pore predisposes individuals to infection-triggered neurologic disease," said ...

RNA emerges from DNA's shadow

... small holes that are connected to the genome by proteins called nuclear pore complexes. In one of the presentations, Nick Proudfoot from Oxford ... the UK explained how some genes are enhanced by being close to the nuclear pore complex, indicating a close relationship between gene expression and ...

November GEOLOGY and GSA TODAY Media Highlights

... the processes at work deep within the mantle. Age variation of pore water iodine in the eastern Nankai Trough, Japan: Evidence for different ... the concentration of a long-lived radioisotope of iodine (129I) in pore waters from the eastern Nankai Trough, offshore the main island of Japan, ...

Carnegie donates landmark clones to biology

... the interactions of the pore-like structures at the membrane surface in plants. In this study they focused on the underlying mechanism of the pore activity by using mutant proteins that cannot shut the pores off with their C-terminus to see how they work in yeast and immature eggs of the frog ...

Sustainable agriculture at the ESA Annual Meeting

... conventional tilling produced lower bacterial diversity. Kumar says that conventional tillage systems disrupt soil particles and decrease soil pore size, which can lead to decreased water and soil access for microbes. Although he recognizes that tillage is necessary, he thinks that farmers can ...

Enzyme doesn't act alone in atrial fibrillation

... knew that an enzyme called calmodulin kinase II is overactive in several heart diseases and believed it played a role in the leaky channels a tiny pore that controls release of calciu through the cell's membrane. In the current study, Wehrens and colleagues were able to show in mouse models that if ...

A tiny frozen microbe may hold clues to extraterrestrial life

... glaciei isn't a pathogen and is not harmful to humans", Dr Loveland-Curtze added, "but it can pass through a 0.2 micron filter, which is the filter pore size commonly used in sterilization of fluids in laboratories and hospitals. If there are other ultra-small bacteria that are pathogens, then they ...

Aluminum-oxide nanopore beats other materials for DNA analysis

... integrity of the nanopore structure and could potentially improve noise performance as well." The nanopore sensors described in the paper had pore diameters ranging in size from 4 to 16 nanometers, and a film thickness of approximately 50 nanometers. Thinner membranes are possible with atomic ...

Regulation of cell proliferation by the OGF-OGFr axis is dependent on nuclear localization signals

... approximately 5 hours, and transit into the nucleus took 8 hours; OGFr remained in the nucleus for up to 8 days. Transport through the nuclear pore and repression of cell proliferation required two of the three nuclear localization signals (NLS) in OGFr. These results show that the pathway for ...

February 2009 Geology and GSA Today media highlights

... and elongation of the respective quadrants. The most likely origin for the basal low-friction zone is in a layer of clay sediment, overpressured by pore water. This layer would be thicker in the "downhill" (northwest) direction, accounting for the asymmetry. Such a layer likely corresponds to ...

AGU journal highlights -- Dec. 31, 2008

... midlatitudes of Mars and known as lobate debris aprons and lineated valley fill are believed to have formed either as debris flows mobilized by pore ice or as debris-covered glaciers. To learn more, Kress and Head define and analyze ring mold craters, which are abundant on debris aprons and ...

Researchers advance knowledge of little 'nano-machines' in our body

... in a number of diseases. For this study, the research team investigated potassium channels built out of four identical subunits, which form a pore through the membrane that can open and close in order to allow or block ion conduction. They solved a long debate in the field: Do the four ...

MIT: Mending broken hearts with tissue engineering

... to set, or cure. He noted that with this ability, coupled with the flexibility of the laser technique, "we might be able to come up with even better pore shapes with better mechanical properties." In a second advantage, the team found that a patch of tissue created from neonatal rat heart cells ...

ORNL nanotechnologies big winners in DOE call

... devices for a variety of renewable energy, transportation and electrical grid technologies. These new materials, which feature controllable nanoscale pore size, can be produced by self-assembly using conventional manufacturing processes. They provide competitive energy and power densities relative to ...

Researchers catch ion channels in their opening act

... to open or close. One model for the movement of the voltage sensor suggests that it moves up and down by only a small amount, tugging on the pore of the ion channel and opening it just enough for ions to get through. In 2003, Roderick MacKinnon, who won a Nobel Prize in chemistry for his work ...

Gene mutations in mice mimic human-like sleep disorder, UT Southwestern researchers find

... in many neurophysiological disorders. The researchers focused on two genes that encode molecules known as ion channels. An ion channel is a pore that spans a cells membrane, opening and closing to allow charged atoms, or ions, to cross the membrane. The coordinated opening and closing of ...

Researchers 'see' structure of open nicotinic acetylcholine ion channels

... of the open-channel conformation in unprecedented detail. As the ionizable amino acids bind and release protons from the watery environment, the pore gains or loses a positive charge that interferes with the normal flow of cations through the channel, Grosman said. After analyzing the data, ...

Breakthrough in plant research

... carbon dioxide necessary for photosynthesis and release moisture into the air. The plasma membranes of the guard cells that surround the stomatal pore contain several types of ion channels which control the opening and closing of the circular guard cells when the plant encounters a stressful ...

Bacteria and nanofilters -- the future of clean water technology

... which function like a sieve. However, the holes in these sieves are microscopic, and some are so small they can only be seen at the nanoscale. pore size in these filters can range from ten microns ten thousandths of a millimetre to one nanometre a millionth of a millimetre. These ...

Biophysical Society announces new and notable symposium speakers

... biophysical and proteomic data. By applying this approach, he and his colleagues have determined the configuration of the 456 proteins in the nuclear pore complex (NPC) and gained insights into the assembly's evolution and architectural principles. The NPC controls the access of macromolecules in and ...

Researchers reveal HIV peptide's possible pathway into the cell

... of testing and validating results. Garcia's computer cluster is now running simulations on the use of antimicrobial proteins which will open a pore in the cell and keep it open, killing the cell. Antimicrobial proteins have promising direct applications for killing harmful cells in the body. ...

Damon Runyon Cancer Research Foundation awards prestigious fellowships to 17 top young investigators

... PhD , with his sponsor Gnter Blobel, MD, PhD, at The Rockefeller University, New York, New York, is investigating core structures of the nuclear pore complex (NPC). Chromosomal translocations of NPC proteins are linked to various types of cancer, including myeloid and lymphoid leukemias. ...

Planting carbon deep in the earth -- rather than the greenhouse

... in the newly-injected seawater over less than a year. This is the type of reaction that would be needed to make carbon dioxide stable in the pore waters, rather like the dissolved carbonate found in still mineral water. (2) The study gives a clear indication that carbon dioxide sequestered ...

Icy calculations on a hot topic

... mathematically, and also made field and laboratory measurements of sea ice, including using X-rays to make CT-scan images of how the microscopic pore structure of ice varies with temperature. ...

AGU journal highlights -- Sept. 6, 2007

... numerical modeling, as well as through comparisons with field and laboratory measurements. The latter included X-ray computed tomography of sea ice pore microstructure as a function of temperature. Their study demonstrates that sea ice displays universal transport properties similar to fluid transport ...

MIT's molecular sieve advances protein research

... is time-consuming and less predictable. pore sizes in the gels vary, and the process itself is ... "No one has been able to measure the gel pore sizes accurately," said Jongyoon Han, the Karl ... at MIT. "With our nanopore system, we control the pore size precisely, so we can control the sieving ...

Researchers solve mystery of how nuclear pores duplicate before cell division

... for Biological Studies watched as new funnel-like pore structures formed from scratch, and inserted ... where they form eight-fold symmetrical nuclear pore complexes. Each protein is present in copies of ... able to recapitulate the insertion of the nuclear pore complex into the nuclear membrane. Using advanced ...

Several minute intermediate stage in virus-cell fusion discovered; opportunity for drug development

... does not open up right away; instead, a small pore can persist for several minutes before adopting ... of time and, in the rare cases in which the pore does not open, it fails to infect the cell at ... to open all the way." Melikyan explained, "The pore is an unstable structure at that moment: some ...
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