Spleen may be source of versatile stem cells
...norrole in regenerative medicine - might contain a population of potentialislet stem cells.In their pursuit of that finding, the MGH researchers investigated thepossible presence of a protein called Hox11 in these cells. In mammals,Hox11 is a controller of key steps in embryonic development - includingthe forma...It's not all genetic: Common epigenetic problem doubles cancer risk in mice
...olon cancer patients and 10 percent of the general population -- the extra IGF2 stems not from a genetic problem... cancer patients and 10 percent or so of the human population who have loss of imprinting of IGF2. Only the Princeton mice have been crossed with the APC mice. B...Male circumcision reduces risk of HIV transmission from women to men
...fHIV infection per act of heterosexual sex among a population withmultiple sexual partners has found that uncircumcised men have morethan twice the risk of acquiring HIV than do circumcised men.In the study, published in the Feb. 15 issue of The Journal ofInfectious Diseases, now available online, Jared Baeten ......family trees, he has discovered that the Antarctic population of minke whales is now the longest surviving whale population on earth. It was also once the largest—many times larger than other estimates. This information is ...Mitochondrial DNA mutations play significant role in prostate cancer
...found that COI mutations were common inthe general population (7.8 percent), but very infrequent (<2percent) in men without prostate cancer, the investigators noted thatmen harboring these mutations are at increased risk for developingprostate cancer."We believe this study provides convincing evidence that m...Antibiotic Resistant Bacterium Uses Sonar-like Strategy to “See?Enemies or Prey
...ture and adapt a similar strategy to help theaging population cope with loss of vision,?says Gilmore.“Secondly, this discovery will help us to develop new ways to treatinfections that are resistant to antibiotics, making them less severe.Based on an understanding of how this toxin system works, we hope todevelo...Genetically modified natural killer immune cells attack, kill leukemia cells
...tory technique for rapidly producing a large, pure population of NK cells from a small sample of blood; and deve...ls quickly stimulated the expansion of the NK cell population to more than10,000 times their original number. The technique triggered growth of NK cells specifica...Ants Genetic Engineering Leads To Species Interdependency
...rkers at all, ahandicap that would lead to certain population failure in the field.The new findings suggest that specialization involving reliance oninterspecific hybrid workers has left these species unable to surviveindependently of one another.Sara Helms Cahan, Glennis E. Julian, Steven W. Rissing, TanjaSchw...Same mutation aided evolution in many fish species, Stanford study finds
...cklebacks evolved from a relatively uniform marine population into today's broad spectrum of shapes and sizes when the last Ice Age ended roughly 10,000 years ago. Because ocean fish quickly evolved into such distinct populations when they colonized new freshwater lakes and streams, they are an ideal model for ...Introduced foxes transformed vegetation on Aleutian Islands from lush grasslands to tundra
... single offspring each year, so their capacity for population increase is quite low. The foxes are mostly off the islands now, but we will probably continue to see the effects for a long time," Estes said. In addition to Croll and Estes, the authors of the Science paper include UCSC graduate student Eric Danne...Researchers trace evolution to relatively simple genetic changes
...affect key parts of the molecule. In addition, one population in Japan used the same gene to evolve low armor, but has no changes at all in the protein coding region. Instead, Kingsley said, "the mutations that we have found are, we think, in the (gene's) control regions, which turns the gene on and off on cue....Octopuses occasionally stroll around on two arms, UC Berkeley biologists report
...affect key parts of the molecule. In addition, one population in Japan used the same gene to evolve low armor, but has no changes at all in the protein coding region. Instead, Kingsley said, "the mutations that we have found are, we think, in the (gene's) control regions, which turns the gene on and off on cue....Circles Of DNA Might Help Predict Success Of Stem Cell Transplantation
...w stem cell transplant will successfully restore a population of infection-fighting cells called T lymphocytes i...thymus will successfully reconstitute their T cell population using donated stem cells," said Xiaohua Chen, Ph.D., first author of the Blood article. "This kind o...First real-time view of developing neurons reveals surprises, say Stanford researchers
...en the tiny square moved left to right, a distinct population of neurons turned fluorescent colors to indicate t...square the reverse direction triggered a different population of neurons to light up. "At first we felt like we let some air out of our own tires with this findi...Study Models Impact Of Anthrax Vaccine
..., theirstudy found that at least 63 percent of the population would need to beimmunized with vaccine before an anthrax attack, which might not bepractical. However, the study found that anthrax vaccination given evenafter an attack could be beneficial in reducing the length of timeantibiotic treatment would be ...Novel ultrafast laser detection of cancer cells also may improve understanding of stem cells
...emia." Naviaux looks forward to examining a wider population of cancer cells to validate the method, combining the resources of his Center with Sandia's laser expertise. A project proposal has been filed with Sandia to support collaborative work between the unique research capabilities of UCSD and Sandia. "Th...Tiny scaffolding allows stem cells to become working fat cells
...e implications for dieting and obesity, a person's population of fat cells has other vital roles. Fat cells extract lipids, or fatty acids, from the bloodstream. They also become a huge reservoir for glucose as well, and play a role in insulins ability to effectively convert glucose into energy. "If we could ...UCSD discovery may help extend life of natural pesticide
...ese parasites infect nearly one-third of the human population and pose a significant health problem in developing countries," said Aroian. "Perhaps one-day vertebrate-safe Bt toxins could be used as human therapies against these parasites." Griffitts and Aroian credit the flexibility of the roundworm C. elegan...TEL2 gene cooperates with MYC gene to provoke B-cell lymphomas
... As the process of apoptosis becomes sluggish, the population of B lymphocytes increases. The greater the number of these cells, the more likely some of them will eliminate their p53 function. Without the ability to commit suicide, these cells will start multiplying entirely out of control. "This is exactly wh...South America's vast pantanal wetland may become next everglades, UNU experts warn
...economy. "This economic development and consequent population growth, pose a new threat to the Pantanal due to t...lantations of soybean and sugarcane ?all fostering population growth. "The resultant pollution of water and soil from farm chemicals, as well as increasing indus...International HapMap consortium expands mapping effort
...donors. However, the samples are identified by the population from which they were collected. Although any two people are 99.9 percent identical at the genetic level, understanding the one-tenth of one percent difference is important because it helps explain why one person may be more susceptible to a certain ...Unprecedented water level rise in Somalia
...ridge limits the accessibility and mobility of the population around the city, affecting daily activities such as commuting to work, school and accessing hospitals and markets. The floods affected at least 170 households. ...Multiple Campylobacter Genomes Sequenced
... cases going unreported, up to 0.5% of the general population may unknowingly harbor Campylobacter in their gut annually. Diarrhea, cramps, abdominal pain, and fever develop within 2? days of picking up a pathogenic Campylobacter species, and in most people, the illness lasts for 7?0 days. But the infection can...How the environment could be damaging men's reproductive health
... be the mechanism involved. "We need a much larger population in order to investigate the implications of these changes on sex ratio of offspring as the number of children born to these fishermen was small. "However, we think the fact that exposure to environmentally derived chemicals can change the sex chromo...Programmable cells: Engineer turns bacteria into living computers
...he new paper applies similar techniques to a large population of cells. "Here we're showing an integrated package where the cells have an ability to send messages and other cells have the ability to act on these messages," said Weiss. The creation of patterns, such as the bull's-eye effect, is a key step in o...Antiretroviral therapy may prevent excess risk of some cancers in people with HIV
... times more frequently than they do in the general population without HIV/AIDS. HAART use was not associated with lower risks of Hodgkin lymphoma or other cancers. Although people infected with HIV had increased risks of cancers of the lung, lip, mouth, and pharynx, no cases of these cancers were found among no...Molecular models advance the fight against malaria
...ll. According to WHO estimates, 40% of the world's population are currently at risk of the disease and approximately 2 million people, mostly children, are killed by malaria annually worldwide. Today marks Africa Malaria Day, organized to promote awareness of the disease in a country where a child is killed eve...Stem Cell Research Shows Potential for Replacing Tissue Damaged in Heart Attacks
... similarly induce ES cells to become a homogeneous population of cardiac myocytes. Working with Diane Rudy-Reil...ardiac embryoids.?Each cardiac embryoid contains a population of beating cardiac myocytes that is nearly homogeneous. “The results are significant because we wer...Single stem cells from bone heal a broken heart
...e first demonstration of a single, human stem cell population derived from the bone marrow that has the capacity to induce generation of new heart cells and formation of new blood vessels ?two key components of successful myocardial repair. The results provide a foundation on which new approaches to repair the ...HIV-1 spread through six transmission lines in the UK
... chain was 445, approximately 2.5% of the infected population at the time. This trend is remarkably similar to the values for the US epidemic, where the number of transmitted infections and prevalence in 1995 reached 5000 and 200,000 infections respectively. The most recent transmission chain identified by the...New lab technique identifies high levels of pathogens in therapy pool
...ate University, the new study assessed the microbe population in a warm hospital therapy pool through a ribosomal RNA analysis that involved cloning and sequencing genes. The team concluded that the microbes, many of them pathogenic, were enriched just inches above the pool's surface by as much as 60 percent. ...Brain-mapping technique aids understanding of sleep, wakefulness
...ce to produce a "tracer" protein only in a certain population of neurons. The tracer, a nontoxic fragment of the tetanus toxin, transfers itself from one neuron in retrograde fashion to neurons "upstream" -- those from which the tracer-producing neuron receives signals. Researchers then track the tracer to map ...Super predators and mass extinctions
... whose numbers fluctuate only slightly as the prey population waxes and wanes. Inevitably, their stable community is disrupted when mutations lead to a super predator that quickly decimates the prey population, which in turn leads to its own demise. The few creatures that survive the predatory apocalypse gradua...Genetically Modified Natural Killer Immune Cells Attack, Kill Leukemia Cells
...tory technique for rapidly producing a large, pure population of NK cells from a small sample of blood; and deve...ls quickly stimulated the expansion of the NK cell population to more than10,000 times their original number. The technique triggered growth of NK cells specifica...Same-Sex Mating Discovered in a Toxic Fungus
...maintained in an organism with a largely unisexual population structure?" Heitman asked. "The fruiting of alpha strains provided a clue." In their laboratory experiments, the researchers found that, rather than being an asexual process, the hallmarks of mating occur during fruiting of alpha isolates. Unisexual...Potential Drug Target For Treating Cocaine Abuse Found
...eople in the United States ?about 1 percent of the population - use cocaine, according to estimates. Of this number, more than 550,000 are crack users. In 2002, 1.5 million Americans were thought to be dependent on or abusing cocaine. "Cocaine is capable of destroying not only the lives of those addicted, but a...Used in a new way, RNA interference permanently silences key breast cancer gene
...f genetic material are become inactive as the cell population continues to expand. "We are a long way from using this technique in patients, but this study shows that that it may be possible to use RNAi in more than just experiments that silence genes temporarily," says the study's principal investigator, Ralp...Brain Scans Reveal How Gene May Boost Schizophrenia Risk
...inations and delusions, affects one percent of the population and is treated with antipsychotic drugs that block dopamine. The prefrontal cortex is critical for motivation, learning in response to reward, and working memory ?functions impaired in schizophrenia, which is thought to involve a dopamine imbalance. ...First technology to remove prions that cause vCJD from blood launched
...the disease for many years, a proportion of the UK population could be incubating vCJD and acting as blood donor...uate supply of blood for transfusion. As the donor population becomes even more limited with each additional residency deferral, it further reduces the potential ...Maine Researchers Find Exceptions to Old Rules of Genetic Inheritance
...aboratory. In feral house mice, 20 percent of the population carries one copy of the t haplotype whereas the remaining 80 percent carries the wild haplotype. According to the distribution predictions set out by Gregor Mendel, the 19th century Austrian monk who studied inheritance in flowering pea plants, males...Are rice and wheat behind China's population boom?
...heat, helps explain the foundation of China's huge population today." ...Habitat use by North Pacific right whales, Eubalaena japonica, in the Bering Sea and Gulf of Alaska
The small population of North Pacific right whales, found during the su...arameters critical to the survival of this remnant population of right whales, habitat use was investigated by scientists at the NOAA National Marine Fisheries Se...New World founders small in number
...he New World was colonized by a surprisingly small population with an effective size of only about 70 individual...y's approach addresses shortcomings in traditional population genetic studies that rely on just one gene and that assume that population sizes have been constant ......earn about their genetic ancestry," said Hammer, a population geneticist. One of his specialties is deciphering prehistoric human relationships using genetics. By comparing the genetic markers, the UA scientists' work will unveil new aspects of people's family trees, ones that are almost impossible to discover...Changing ecosystems throw scientists mega-challenges
...ssibility of water," it says. With continued human population growth and the uncertain impacts of of environmental change, the report states, ensuring an adequate quantity and quality of freshwater for sustaining all forms of like is a growing challenge. " Integrated, multidisciplinary, and multi-scale, water-r...Stanford gut check shows diversity of intestinal ecosystem
...wing statistical techniques from field ecology and population genetics, Paul Eckburg, MD, a postdoctoral scholar in infectious diseases and geographic medicine, conducted the most extensive study to date surveying the inhabitants of the lower digestive tract. In the three healthy subjects he studied, he found 3...Low oxygen likely made Great Dying worse, greatly delayed recovery
...animals to cross from one valley to the next. That population fragmentation likely increased the extinction rate and slowed recovery following the mass extinction, Huey said. "Biologists have previously thought about the physiological consequences of low oxygen levels during the late Permian period, but not ab...Scientists reveal the shape of a protein that helps retroviruses break into cells
...animals to cross from one valley to the next. That population fragmentation likely increased the extinction rate and slowed recovery following the mass extinction, Huey said. "Biologists have previously thought about the physiological consequences of low oxygen levels during the late Permian period, but not ab...Stem cell research - new cell lines
...chers are one step closer to deriving a homogenous population of cells of a particular type. "There are about 2...blem. It gives the hope that we can produce a pure population of those cells in large numbers and transplant them into the patient." The researchers are currentl...A New Species of Monkey is Discovered in Tanzania: The First in Africa for More Than 20 Years
...and critically endangered, with an estimated total population of between 500 and 1,000 animals. Also noted by D...s in good condition, but there is concern that the population of the highland mangabey in this forest is very small and limited in distribution. Ehardt observes t...AIDS Public Awareness Campaign Expands Following Report Of Rapidly Progressive HIV
...o better monitor HIV drug-resistant strains in the population and further strengthening access to HIV counseling and testing. Earlier this month, the New York City Department of Health and Mental Hygiene reported a highly resistant strain of rapidly progressive HIV diagnosed in a New York City resident. The pa......ulations. If the virus had killed off much of the population of both species, it may have created what evolutionary biologists call a population bottleneck. This much smaller group of surviving animals would then sort out most of its genetic var...Cousin of Asian super termite invades Florida
... UF researchers have discovered a well-established population in Riviera Beach, more than 70 miles north of Miam...olting, thereby reducing the ability of the worker population to sustain underground colonies. The chemical has a low toxicity to humans and the environment. Less...Prescription Drug Patches Gaining Ground, Tackling New Therapies
...veral factors ?factors with strong demographic and population trend underpinnings. Technology has also played a major role in prescription patch growth. Advances in synthetic materials and patch design have led to patches that are more esthetically acceptable and that are capable of delivering sustained dosing ...Butterfly migration could be largest known
... of plants for the caterpillars to eat, fuelling a population boom, Shapiro said. The butterflies take about three days to reach the Central Valley, and the current generation will fly as far as southern Oregon. Their offspring will fly on to reach British Columbia by summer, before heading south again in the ...Bee mites suppress bee immunity, open door for viruses and bacteria
...probably arose in the Eastern or Chinese Honey Bee population and hopped over to the United States in 1987. They quickly infested western or European honey bees. One sign of infection is the presence of bees with deformed wings. Also, sometimes seemingly healthy colonies become ill and the complete hive collaps...Chimp genome reveals a retroviral invasion
...tter understanding of the evolutionary history and population genetics of great apes will help identify the most likely scenarios. And knowing how these retroviral elements infiltrated some apes while sparing others could provide valuable insights into the process of evolution itself. Citation: (2005) The Chim...Single-donor Islet Transplantation Procedure Shows Promise For Patients With Type 1 Diabetes
...n islet transplantation, further study in a larger population with longer follow-up will be critical to assess the risk-benefit ratio of this emerging therapeutic option," the researchers conclude. ...A hope for oil spill bioremediation
...as to assess the response of the natural bacterial population after the spill and to detect evidences of crude o... the Prestige crude oil, pointing out to a natural population oxidizing this carbon source into CO2. This could be reproduced in the laboratory using water sample...Mutation in clams protects against paralytic shellfish poisoning but raises human health risk
... function differently, with those from exposed the population showing markedly less sensitivity to the toxins. Tracking these differences down to the genomic level and comparing DNA sequences from the two populations enabled Connell to identify the single nucleotide mutation that corresponded with toxin resist...