Point in Biological News

Comprehensive look at rare leukemia finds relatively few genetic changes launch disease

... as copy number alterations (CNAs). To identify point mutations, the researchers also performed DNA ... 25 genes that are commonly mutated in adult AML. point mutations involve a single chemical change in the ... than two CNAs per AML patient, and less than one point mutation per patient in the genes sequenced. The ...

Trans fats hinder multiple steps in blood flow regulation pathways

... the buildup of plaque in the arteries to the point where it interferes with blood flow. "The ... and this plaque buildup continues to the point where it will stop blood flow." Trans fats ... special qualities, such as the lower melting point of margarine that makes it creamy at room ...

NIH announces new program to develop therapeutics for rare and neglected diseases

... effect. Too often, the process gets stuck at the point of discovery because few academic researchers can ... promising treatments for rare diseases to the point that they are sufficiently "de-risked" for ... lay the groundwork for clinical trials once that point in the drug development is reached. TRND is ...

UCSB scientists document fate of huge oil slicks from seeps at coal oil point

... offshore from petroleum seeps near Coal Oil point in the Santa Barbara Channel. Their research, ... "rectangle along the coast from Santa Barbara to point Conception," would match the trail of the plume. ... All the oil seems to be biodegraded to the same point and then it just stops." "It's dramatic how ...

BIO-key(R) Granted Patent for Trusted Biometric Device Security Solution

... Secure Private Data in Transit from Capture point Protects Privacy of Users While Enhancing ... covers the transmission of information from the point the information is collected at the biometric ... or redirection. Securing the information from the point where it is initially captured (the fingerprint ...

Therapeutic cloning gets a boost with new research findings

... a five to ten-fold lower rate of spontaneous point mutations than adult somatic cells, which give ... does not lead to an increase in the frequency of point mutations. John McCarrey, professor of ... does not lead to an increase in the frequency of point mutations in cloned mice, the team also found ...

Frog's immune system is key in fight against killer virus

... She adds: "This discovery has helped identify the point in our evolutionary history when this ... and Chemical Sciences added: "From a scientific point of view we could learn as much about the fight ... frogs succumb or they don't; but from a personal point of view I hope these changes are the first signs ...

Gene mutation increases drug toxicity, rejection risk in pediatric kidney transplants

... form. During this time, patients with a specific point mutation in the gene that helps break down the drug, UGT, metabolize the drug slower. This point mutation, called UGT1A9-331, causes overexposure ... off the drug or have their dosage reduced to the point where they risk rejection of the new organ. ...

January-February GSA Bulletin media highlights

... the northern Irish Sea Basin during the Killard point stadial at around 16.5 thousand years before ... by around 15.0-15.5 thousand years B.P. Killard point stadial moraines have been mapped elsewhere in ... that constrain the age of retreat of the Killard point stadial ice margin from western Ireland. Eight ...

How chromosomes meet in the dark -- Switch that turns on X chromosome matchmaking

... this system found that in that a key tipping point was reached if the amount of CTCF present in the ... around 0.1 mg per millilitre or less. Below that point very little happened. Random bindings did occur ... concentration is reached it produces a tipping point or thermodynamic switch. That particular ...

Case Western Reserve finds mechanism underlying alt. splicing of premessenger RNA into messenger RNA

... deletes a section of pre-mRNA from that beginning point to a common ending point downstream of both beginning splice points. ... changes in a nucleotide sequence near a splice point can lead to large changes in splice site choice ...

Timetable for Puget Sound restoration suffers setback

... in sediments decreased more rapidly after major point sources, like the Tacoma smelter, were closed. ... insults following removal of the smelter point source, as well as how quickly this process ... growth More recently, however, regulation of point sources has grown less and less effective at ...

EPA and USDA should create new initiative to better monitor nutrients

... to release nutrients -- EPA should require major point sources to monitor the nutrient concentrations of ... being delivered to the Gulf of Mexico from these point sources is roughly 10 percent of the total, the ... reduce uncertainties in the estimates of point source nutrient discharges, the committee said. ...

American Chemical Society's Weekly PressPac -- Nov. 19, 2008

... of faculty and graduate student collaborators, point out that bacterial contamination of medical ... . In the study, Benjamin Miller and colleagues point out that MMD differs from typical hereditary ... In the new study, Peter R. Shewry and colleagues point out that whole grain foods, including wheat, rye ...

Forgotten but not gone -- how the brain takes care of things

... cell towards its neighbours. Whenever a special point of contact, called synapse, forms at the end of ... leader Mark Hbener explains. Everything seems to point to the fact that synapses are only disabled, but ... that has been made may occur again at a later point in time, the brain apparently opts to save a few ...

American Chemical Society Weekly PressPac Oct. 15, 2008

... In the study, Andrei P. Sommer and Dan Zhu point out that high-intensity visible light has been ... a monthly journal. Eyal Zussman and colleagues point out that researchers have tried for years to ... In the study, Carey King and Michael Webber point out that as the need for alternative ...

Researchers develop new self-training gene prediction program for fungi

... gene prediction in locations called branch point sites," said Mark Borodovsky, director of Georgia ... and Computational Genomics. Branch point sites are located inside introns, which are ... of eukaryotic genes, we didn't search for branch point sites, but doing so in the new program helps to ...

ACS PressPac -- Sept. 17, 2008

... In the study, Tayfun Babadagli and colleagues point out that oil trapped in the world's oil shale ... the new study, Salvador Garrigues and colleagues point out that the purity of heroin can vary widely, ... Proteome Research. Jiahao Sha and colleagues point out that scientists do not understand one effect ...

American Chemical Society's Weekly PressPac -- Sept. 10, 2008

... In the new study, Chang-Guo Zhan and colleagues point out no effective anti-cocaine medication ... In the new study, Atsushi Kato and colleagues point out that chamomile, also known as manzanilla, has ... bi-monthly journal. Qingfeng Li and colleagues point out that the FPLA has only one moving part and is ...

Restoring Alabama's coast

... projects at two sites: the northeast shoreline of point aux Pins and the undeveloped shoreline on the southwest side of the Boggy point boat ramp site in Orange Beach. Both of these ... construction projects will commence at Boggy point ...

American Chemical Society's Weekly PressPac -- Aug. 6, 2008

... Food Chemistry . Jrgen A. Richt and colleagues point out that removal of brain, spinal and other ... publication. Niclas Karlsson and colleagues point out that researchers have known for years that ... study, Maria Del Pilar Castillo and colleagues point out that pesticide spills are common when farmers ...

American Chemical Society's Weekly PressPac -- July 23, 2008

... Chemistry . Peter Schieberle and Luigi Poisson point out that more than 300 compounds have been ... Andrei Sommer, Dan Zhu, and Hans-Joerg Fecht point out that scientists have theorized for years that ... In the new study, Fang-Jie Zhao and colleagues point out that rice a staple crop for 2.5 billion ...

American Chemical Society's Weekly PressPac -- July 16, 2008

... In the study, Stephen B. H. Kent and colleagues point out that scientists have tried for years to ... the new study, David E. Cane and Chieh-Mei Wang point out that these two substances, geosmin and ... In the new study, Yuyu Sun and Jie Luo point out that Kevlar fabrics are widely used as ...

American Chemical Society's Weekly PressPac -- July 9, 2008

... study, Jurgen Schmidt, Suri Iyer, and colleagues point out that conventional tests for flu viruses ... In the new study, Juan J. Calvete and colleagues point out that researchers have known for decades that ... Alexander Tullo, and Jean-Francois Tremblay point out that so-called 'electronic chemicals' play ...

American Chemical Society's Weekly PressPac -- July 2, 2008

... In the new study, Yuji Teramura and Hiroo Iwata point out that transplantation of the pancreas's ... In the new study, Masahiko Inouye and colleagues point out that scientists have tried for years to ... A. Davis and Aleksandr Simonian and colleagues point out that concern over the role of contaminated ...

American Chemical Society's Weekly PressPac -- June 25, 2008

... . In the study, Joseph Kanner and colleagues point out that scientists attribute wine's health ... . In the study, Adamo Valle and colleagues point out that women, on average, live years longer ... the new study, Alirio E. Rodrigues and colleagues point out that microcapsules, or submicroscopic shells, ...

American Chemical Society's Weekly PressPac -- May 28, 2008

... journal. Marc Edwards and colleagues point out that more water purification plants in the ... In the new study, Adriana Bravo and colleagues point out that past efforts to keep beer fresh have ... Alihosseini, her adviser Gang Sun and colleagues point out that conventional dyes and pigments used in ...

Pacific coast turning more acidic

... food web, may also be susceptible, the scientists point out, although other species of open-ocean ... 310 parts per million the highest level to that point that the Earth has experienced in the last ... If were right on the edge now based on a starting point of 310 parts per million, Hales said, we may have ...

Wakame waste

... is becoming an increasingly pressing issue. They point out that various species of seaweed are able to extract toxic compounds from seawater and point to the brown seaweed, Undaria pinnatifida, known ... of marine bioremediation. The researchers point out that there may be a simple solution to the ...

Sudden 'ecosystem flips' imperil world's poorest regions, say water experts

... agriculture and land-use practices. Our main point is that these effects arent necessarily going to ... nutrients in the soil you eventually get to a point where you can even completely stop farming and ... the School of Environment. You go past a tipping point where its very difficult to reverse. Ecosystem ...

Tipping elements in the Earth's climate system

... temperature and ablation. The exact tipping point for disintegration of the ice sheet is unknown, ... of ocean water could destabilize it. The tipping point could be reached with a local warming of five to ... Celsius could push the element past the tipping point so that deep water formation stops. Under these ...

Scientists outline novel approach to ecosystem management

... have never occurred before. As the authors point out, In managing novel ecosystems, the point is not to think outside the box, but to recognize ... such as eradicating invasive species. The authors point out, however, that in many cases this approach ...

1 person out of every 1,000 has synaesthesia, in which an individual can smell a sound

... or hear colours. Actually, all of as, at some point in our lives, have had this skill (some authors ... consider it a mistake. The synaesthete might even point out that the word is ugly or that he or she does ... Moreover, they can affect the synaesthete to the point of slanting his or her preferences when faced ...

American Chemical Society's Weekly PressPac -- Nov. 28, 2007

... In the new study, Bruce E. Logan and colleagues point out that so-called acid-mine drainage (AMD) is a ... the study, Perttu E. P. Koskinen and colleagues point out that ethanol and hydrogen are two leading ... those from springs that approached the boiling point of water, the scientists enriched promising ...

Further development of Water Framework Directive necessary

... monitored in rivers throughout Europe is a weak point of the existing Directive. "This priority list, ... 1970s and is therefore no longer used. From our point of view, it would be better for this important ... of the riverbed and river bank area. From this point of view, the Water Framework Directive is in ...

The power of multiples: Connecting wind farms can make a more reliable - and cheaper - power source

... that one will be on a treadmill at any given point in time and your chances of running, say, your ... Interconnecting multiple wind farms to a common point and then connecting that point to a far-away city reduces the cost of ...

American Chemical Society's Weekly PressPac -- Oct. 31, 2007

... Dalibor Sames and Mary K. Froemming point out that the enzyme 17B-HSD10 has stirred ... the study, Donald Scavia and Kristina A. Donnelly point out that the Gulf of Mexico has one of the ... In the study, Gow-Chin Yen and Chin-Lin Hsu point out that large amounts of those compounds occur ...

The conservation lens

... Goffinet (University of Connecticut, Storrs) point out, in the sub-Antarctic Magellanic ecoregion ... trends between vascular and nonvascular plants point to the limitations arising from relying on a ... to define conservation priorities. They also point out the benefits of international collaborations ...

In-vitro fertilization improved with 3-D/4-D-guided embryo transfer and new placement target

... imaging to guide the placement of embryos to the point where the endometrium is most receptive to ... identified a new embryo placement target as the point where the fallopian tubes would intersect if they ... titled "Maximal Implantation Potential (MIP) point - Suggested Target for Optimal Embryo Placement ...

Using nanotubes to detect and repair cracks in aircraft wings, other structures

... had to travel around the crack to get from one point to another, the electrical resistance the ... through the carbon nanotubes at a particular point in the grid. This extra voltage creates heat, ... a change in electrical resistance at some point in the structure. The system should help ...