Plasma in Biological News

Yale researchers uncover secrets of salmonella's stealth attack

... the external membrane of the cell, called the plasma membrane, to coax the cell into taking in the ... order to accomplish this, SopB must move from the plasma membrane of the cell to the membrane of the ... machinery that normally moves proteins from the plasma membranes to internal vesicles. "These ...

Humans may be losers if technological nature replaces the real thing

... conducted by Kahn's laboratory, one with a plasma display "window" and several with AIBO, a robotic dog. The plasma window study showed that people recovered better ... high-definition television scene displayed on a plasma window. "What do we compare technology to? If ...

Simple test helps predict heart attack risk

... of three conditions: an abnormal ABI or elevated plasma fibrinogen or elevated plasma C-reactive protein (CRP). "Even with abnormal ... further tests are needed. Elevated results for plasma fibrinogen ...

Using hair to manage HIV/AIDS and predict treatment success

... Clinicians can draw blood and then measure plasma levels of medications, but since a single plasma level represents medication exposure only hours ... the "snapshot" of exposure provided by a single plasma level of medication, Gandhi said. "Hair ...

Researchers describe protease inhibitor that may aid in diabetic retinopathy treatment

... that a specific inhibitor of the protease plasma kallikrein, ASP-440, developed by ActiveSite ... step towards understanding the importance of plasma kallikrein as a target in diabetic eye disease ... research, Joslin researchers identified plasma kallikrein as a potential therapeutic target in ...

Caltech scientists develop 'barcode chip' for cheap, fast blood tests

... of blood is introduced, protein-rich blood plasma is separated from whole blood, and a panel of ... separate whole blood cells from the plasma. The plasma is then assayed for specific proteins. "The ... the blood through a channel. As the blood flows, plasma is skimmed into narrow channels that branch off ...

AGU journal highlights: Nov. 11, 2008

... a neutral tail with debris along the orbit, and a plasma tail with an induced magnetosphere driven by ... spacecraft, the authors study cold ionospheric plasma and find that solar forcing sweeps ions from the ... Title: A comet-like escape of ionospheric plasma from Mars Authors: R. Lundin, S. Barabash, M. ...

Plasma DNA level is a reliable marker of recurrent esophageal cancer, study finds

... the American College of Surgeons shows elevated plasma DNA is a reliable marker of recurrent esophageal cancer. The study also suggests that plasma DNA levels rise before clinical evidence of ... Although carcinoembryonic antigen (CEA) and plasma DNA are known to be elevated in patients with ...

Study identifies trends of vitamin B6 status in US population sample

... United States population based on measures of plasma pyridoxal 5'- phosphate (PLP) levels in the bloodstream. plasma PLP is the indicator used by the federal ... (NHANES). Vitamin B6 inadequacy was defined as a plasma PLP concentration less than 20 nmol/L. To the ...

Hyperviscous fluids: Better treatment for severe blood loss

... to 55 percent of normal. Hextend and alginate are plasma volume expanders, substances transfused to ... our studies indicate that Hextend and similar plasma extenders could produce even greater benefit if ... portion of blood. For example, higher viscosity plasma causes arterioles to dilate. For centuries, ...

Biomarkers allow doctors to match therapy to patient

... cell lung cancer. The researchers also monitored plasma levels of VEGF. They assessed tumor response with ... the ccEPC increases paralleled the rise in plasma VEGF levels; they decreased during the two-week ... and erlotinib, ccEPC levels increased, while free plasma VEGF levels decreased. ccEPCs did not rise in a ...

New insights into how lasers cut flesh

... as a plasma. At the end of each laser pulse, the plasma collapses and the energy released produces the ... This is the first study that looks at the plasma dynamics of ultraviolet lasers in living tissue, ... involves the origination of the individual plasma bubbles. All it takes to seed such a bubble is a ...

AGU journal highlights -- Sept. 6, 2007

... Magnetic reconnection is a fundamental plasma process in which pairs of magnetic field lines ... signatures of reconnection is the acceleration of plasma away from a reconnection site in a pair of oppositely directed plasma jets. Gosling et al. utilize 3-second ...

Paracetamol, one of most used analgesics, could slow down bone growth

... paracetamol slows down bone regeneration. plasma rich in growth factors Research of Garca Mart ... in culture, the author also studied the effect of plasma rich in growth factors (obtained from patients' ... after a spinning process). Application of this plasma gel on bones accelerates their growth, without ...

Diverse genetic abnormalities lead to NF-κB activation in multiple myeloma

... a target for MM therapy. MM is a cancer of the plasma cell, a blood cell that produces antibodies to ... study results in the accumulation of malignant plasma cells beyond the physiological control of the ... signaling in MM and describe a shift of plasma cells from dependence on the microenvironment to ...

In vitro antibody production enables HIV infection detection in window period -- key to safer blood

... of antibodies against HIV-1 prior to their detection in corresponding plasma samples in a group of donors who would otherwise be classified as HIV-1 ... of Technology, ran the same HIV antibody tests using both regular plasma and SMART-plasma (plasma after the Stimmunology step) from blood donors in ...

Advance in understanding cellulose synthesis

... individual cellulose synthase complexes as they were delivered to the plasma membranethe permeable film that surrounds the cell, but is inside the cell ... synthase complexes disappear and organelles accumulate just under the plasma membrane. These organelles contain cellulose synthase and are tethered to ...

Story tips From the Department of Energy's Oak Ridge National Laboratory -- May 2009

... used the XGC1 code to verify that turbulence in the well-confined edge of plasma in a fusion reactor can penetrate the core and boost its temperature. ... tracks individual particles in a given state and simultaneously simulates plasma at the edge and core. This research was funded by the Department of Energy ...

A little wine boosts omega-3 in the body: Researchers find a novel mechanism for a healthier heart

... alcohol intake is associated with higher levels of omega-3 fatty acids in plasma and red blood cells. This is the major finding of the European study ... women and two for men, had higher concentration of omega-3 fatty acids in plasma and red blood cells independently of their fish intake". However ...

Site used by sodium to control sensitivity of certain potassium ion channels

... According to Logothetis, ion channel proteins are found in the plasma membrane of cells and provide a path for hydrated cations such as calcium, ... hydrated ions do not travel through the lypophillic, or fat-based, plasma membrane because they are surrounded with water and require a pathway to ...

NSF awards two grants to Stevens for nano/micro device fabrication and nano sensor development

... Foundation for the project, "MRI: Acquisition of an Inductively Coupled plasma Etching System for Nano/Micro Device Fabrication." The Stevens team ... sensors, actuators and devices at Stevens. By using an Inductively Coupled plasma (ICP) etching system, the team can greatly augment existing micro/nano ...

Novel structure proteins could play a role in apoptosis

... is a cytoskeletal protein that lines the intracellular side of the plasma membrane of many cell types in pentagonal or hexagonal arrangements, forming scaffolding that plays an important role in maintenance of plasma membrane integrity and cytoskeletal structure. D'Agostino said the next ...

Genetic variant increases triglyceride levels in Asian-Americans

... polymorphism in the APOA5 gene (553 G>T shift) is associated with elevated plasma TG levels, which like cholesterol, increase the risk of heart disease. ... 541 individuals and found that 15.1% of Chinese-Americans with high plasma TG (>150 mg/dl) carried at least one copy of the 553T variant, compared ...

Post-exercise caffeine helps muscles refuel

... the caffeinated drink resulted in higher levels of blood glucose and plasma insulin several signaling proteins believed to play a role in glucose ... blood into the muscles. However, the higher circulating blood glucose and plasma insulin levels were likely to be a factor. In addition, caffeine may ...

Niacin's role in maintaining good cholesterol

... and thus lower the risk of heart disease. While niacin can increase plasma HDL levels, the mechanism of how it works has been mysterious, although ... hinders the liver from removing HDL from the blood, thus maintaining high plasma HDL levels. Importantly, niacin does not affect another major pathway ...

A new analysis method allows to find out the sex of the baby from the second month of pregnancy

... foetus from the eighth week of pregnancy separating the DNA found in the plasma of the pregnant woman. This new finding has been tested through a ... during pregnancy, between 3.4 and 6.2% of the total DNA free in mother plasma has a foetal origin. Therefore, a simple peripheral blood sample is enough ...

AGU Journal Highlights -- March 19, 2008

... from Io Io, the innermost large moon of Jupiter, orbits within a plasma torus that forms when neutral atoms in Ios atmosphere are ionized and ... the main bright spot. If Io is orbiting in the southern part of the plasma torus, this leading spot is seen in the northern polar regions, and vice ...

Turtle studies suggest health risks from environmental contaminants

... Advancement of Science (AAAS) that a scientific team monitoring the blood plasma of loggerhead turtles along the U.S. East Coast consistently found ... Keller said that in a 2005 study,* PFC concentrations measured in the plasma of turtles found along the coast from Florida to North Carolina indicated ...

Media highlights in the January issues of Biophysical Journal

... January 15, 2008 Translocation of Aquaporin-Containing Vesicles to the plasma Membrane is Facilitated by Actomyosin Relaxation Christoph P ... regulation. Shuttling vesicle-embedded proteins from cytosol to the plasma membrane is an essential process for living cells. Biochemists have ...

Human hormone blocker found to help prevent obesity and diabetes: study

... a 50-day period. Food intake and body weight were recorded daily while plasma glucose and insulin concentrations were monitored at 5-7 day intervals. ... of the high fat diet resulted in progressive weight gain and elevations of plasma glucose and gyrated hemoglobin, leading to impaired insulin sensitivity ...

BMI criteria for obesity surgery should be lowered, UT Southwestern researcher suggests

... ability to store excess calories as fat. This prevents changes in plasma metabolites, such as triglycerides and cholesterol, which promote risk for ... fat and who only accumulate fat in the upper body often have excessive plasma concentrations of triglycerides and cholesterol, which will increase their ...

Insulin's brain impact links drugs and diabetes

... dopamine was significantly reduced. The lack of the protein on the plasma membrane prevents the amphetamine-induced increase in extracellular ... diabetic rat, loss of insulin has compromised DAT trafficking to the plasma membrane, Avison said. These experiments show that there is likely a ...

Obama administration announces more than $327 million in Recovery Act funding for science research

... Light Source to study high energy density plasmas; and $1.8 million for improvements at the Stanford Synchrotron Radiation Lightsource. Princeton plasma Physics Laboratory; Princeton, NJ$13.8 million, including $8.8 million for a variety of initiatives in fusion energy research and $5 million for ...

Cancer's distinctive pattern of gene expression could aid early screening and prevention

... single gene that is methylated in the majority of the broad group of cancers called non-Hodgkin's lymphoma. This methylated DLC1 is detectable in the plasma samples of lymphoma patients, making it a good candidate for the screening, says Dr. Shi who also is looking for these types of biomarkers in breast ...

Children's Hospital of Pittsburgh of UPMC scientists identify enzyme important in aging

... Ph.D., an endocrinology researcher at Mayo Clinic. In this "knockout" mouse model, researchers deleted an enzyme known as pregnancy-associated plasma protein A (PAPPA). PAPPA-knockout mice live at least 30 percent longer and have significantly lower occurrence of spontaneous tumors than typical ...

Plant protein 'doorkeepers' block invading microbes, study finds

... known as RIN4, which is able to regulate these two branches of the plant immune system in Arabidopsis. The protein is found in the permeable plasma membrane that encases the cell on the inside of the cell wall. It has been unclear exactly how the protein and the two branches of the immune system ...

Plant protein 'doorkeepers' block invading microbes, study finds

... known as RIN4, which is able to regulate these two branches of the plant immune system in Arabidopsis. The protein is found in the permeable plasma membrane that encases the cell on the inside of the cell wall. It has been unclear exactly how the protein and the two branches of the immune system ...

Research explores interactions between nanomaterials, biological systems

... tissues and various life forms in different natural environmental contexts. When nanomaterials enter a biological fluid for example, blood, plasma or interstitial fluid the materials' surface may be coated with proteins. Understanding how these protein layers change the properties of the ...

Versartis presents positive preclinical data on 2 product candidates at ENDO 09

... Officer of Versartis. "Our preclinical data presented today show that VRS-317 demonstrated in vivo potency equal to daily hGH, and sustained plasma levels and pharmacodynamic responses in monkeys without toxicity. Potential benefits of VRS-317 include its stability at room temperature in a ...

Sulphur in just one hair could blow a terrorist's alibi

... is able to detect these small variations. "The new method is based on combining a laser ablation system and multicollector inductively-coupled plasma mass spectrometry (abbreviated to LA-MC-ICP-MS)", Rebeca Santamara-Fernndez of LGC, lead author of the study, tells SINC. To summarise, the laser ...