Placebo in Biological News

Your brain on -- and off -- caffeine

... which involved the administration of caffeine and placebo capsules. Each participant's response to the caffeine or placebo was measured using three different measures ... of chronic caffeine maintenance with chronic placebo maintenance, which provides unique information ...

Lancet study supports new, highly effective treatment for blood disorder

... control group received the standard of care and a placebo pill. By the end of the 43-day testing ... compared with 16 percent of subjects in the placebo group. A safe-level platelet count is between ... likely to reach the target platelet counts as the placebo group. Currently, patients are treated with ...

Genes determine whether sugar pills work

... have now found gene variants that can impact the placebo effect and a mechanism in the brain that ... under one fourth of the subjects were given a placebo instead of a drug. This was a double-blind ... was decoded, it turned out that 40 percent of the placebo group had received the same degree of anxiety ...

Vitamin K does not stem BMD decline in postmenopausal women with osteopenia

... to receive either 5 mg of vitamin K1 or a placebo daily for two years. Two hundred and sixty one of ... by similar amounts in both the vitamin K and the placebo groups. Over the four-year period, fewer women ... K group had fractures (9 versus 20 women in the placebo group) and fewer women had cancer (3 versus 12). ...

Scientists suspect omega-3 fatty acids could slow acute wound healing

... of IL-1b in their blister wounds than did the placebo group 24 hours after the wounds were created. The ... in their blisters over time than did the placebo group, but those differences in levels were not ... group and an average of 9.8 days in the placebo group, but the difference was not significant. ...

Wellmune WGP supplementation alleviates

... daily with either 250mg of Wellmune WGP or a placebo for 90 days. Wellmune WGP is a natural ... wellness and vitality. In contrast with the placebo group, study participants who received Wellmune ... with 1.38 days of work/school missed for the placebo group). In addition, although there were no ...

Effective ADHD treatment found for children with fragile X syndrome

... months, which involved 500 milligrams of LAC or a placebo given twice daily. Patients were evaluated by an ... months and 12 months. The effects of the drug and placebo were evaluated using a set of neuropsychological ... to stimulants. The patients treated with the placebo also showed reduced hyperactive behavior, ...

New clinical data shows chromium picolinate improves cognitive function

... enhanced motor speed relative to those receiving placebo (p = 0.16). Another component of the study ... from the chromium picolinate group and from the placebo group showed that the subjects receiving the ... with working memory. The subjects receiving placebo showed no such change. At the completion of ...

HGS announces positive Phase 2 LymphoStat-B at ACR meeting

... laboratory abnormalities remaining comparable to placebo or decreasing through 2.5 years of treatment ... reductions in SLE disease activity versus placebo as measured by the SELENA SLEDAI and BILAG ... over time in patients crossing over from placebo to LymphoStat-B after 52 weeks. If the Phase 2 ...

New Actemra data shows significant benefit for patients suffering from rheumatoid arthritis

... (8mg/kg) every four weeks plus DMARDs weekly or placebo infusions plus DMARDs weekly. The multicentre ... versus 25%, 9% and 3%, respectively, in the placebo plus DMARDs arm. Disease remission was ... every four weeks plus methotrexate weekly or placebo infusions plus methotrexate weekly. The study ...

Clinical studies show REMICADE reduces incidence of bowel surgeries in ulcerative colitis patients

... through 54 weeks, compared to those receiving placebo (p=0.015). REMICADE is the first and only ... to receive REMICADE 5 mg/kg, REMICADE 10 mg/kg or placebo at weeks 0, 2, 6 and every subsequent 8 weeks ... two years. Patients who had responded to placebo also enrolled in the extension to maintain the ...

Got zinc? New zinc research suggests novel therapeutic targets

... in the elderly." Scientists administered either a zinc supplement or a placebo to healthy volunteers to assess the effects of zinc on T cell activation. ... from the zinc-supplemented group had higher activation than those from the placebo group. Specifically, cell activation stimulated the zinc transporter in T ...

Results from trials of DHA in Alzheimer's disease and age-related cognitive decline

... blind, randomized, placebo-controlled clinical trial comparing DHA and placebo in 402 people (average age=76) diagnosed with mild to moderate Alzheimer's ... DHA intake of less than 200 mg per day. Subjects were treated with DHA or placebo at a dose of two grams per day for 18 months. Those participants already ...

Omega-3 fatty acids appear to impact AMD progression

... AMD. AREDS study participants were randomly allocated to receive either a placebo or supplements containing the antioxidants vitamins C and E and beta ... "In our study, we observed participants with early stages of AMD in the placebo group benefited from higher intake of DHA, but it appears that the ...

Novel lung cancer vaccine shows promise in fighting early-stage lung cancer

... Cell LunG Cancer Immunotherapy) study is a randomized, double-blind and placebo controlled trial that will enroll patients with MAGE A-3-positive, ... to treatment with the MAGE-A3-targeting vaccine and 60 patients received placebo vaccines. The preliminary research shows that the treatment was well ...

Study finds 'rescue course' of antenatal steroids improves outcome in premature babies

... 437 patients were randomized (233 in the study group, and 214 in the placebo group). The results showed a significant reduction in composite neonatal ... for babies born prior to 34 weeks in the "rescue steroid" group vs. placebo (43.9% vs. 63.6%) as well as significant decrease in respiratory distress ...

Vitamin E shows possible promise in easing chronic inflammation

... acute systemic inflammation. The effects were compared with those found in placebo control groups. The research team examined the impact the Vitamin E or placebo treatment had on the mRNA and protein levels of three cytokines ...

Statin does not appear helpful for children with learning disabilities caused by genetic disorder

... function of 62 children with NF1. The participants received simvastatin or placebo treatment once daily for 12 weeks. After the treatment period, there was no significant difference between the simvastatin and placebo groups on several cognitive measures (determined by testing), including ...

Study finds Chinese food good for your heart

... it clinically in a double-blind manner with a purified product against a placebo group until now and we are pleased with the results. However, people in ... year. Study participants were given two-300-milligram XZK capsules or a placebo and tracked over a five-year period. The XZK capsules contained a ...

People with diabetes may have all natural citrus supplement

... medications were randomly assigned to receive either Diabetinol or a placebo twice per day for three months. Each subject had mildly to moderately ... glucose over the four hours of a standard oral glucose challenge. The placebo group showed no significant improvements in glucose intolerance. A ...

New study shows Dermytol produces pronounced decrease in malignant melanoma tumor volume

... part of the study, researchers applied either a Dermytol cream or a placebo cream onto the shaved skin of a different group of mice. After seven days ... of the mice were injected with malignant melanoma tumor cells. Dermytol or placebo treatments continued for 25 days. The mice in both Dermytol groups ...

Ibuprofen or acetaminophen in long-term resistance training increases muscle mass/strength

... ibuprofen and acetaminophen caused a substantially greater increase over placebo in the amount of quadriceps muscle mass and muscle strength gained during ... would significantly increase muscle mass and strength. They expected the placebo group to show such increases, as its members did, but they were surprised ...

Tamiflu effective for treatment and prevention of influenza in children 1 year and older

... almost a third (29%) and illness duration by a quarter (26%) compared to placebo when initiated within 48 hours of onset1. New data presented showed that ... in severe ear infections (otitis media) in the Tamiflu group compared to placebo if treatment was started within 24 hours2. Tamiflu given as prevention ...

New genetic research into nicotine addiction shows promise for personalized treatment

... nicotine and serotonin. Participants were then provided with either placebo or bupropion treatment for ten weeks and followed up for 6 months. ... variant of the gene (wild type variant) had good abstinences rates on placebo and gained no additional benefit from Bupropion, suggesting no benefit ...

New supplement may help slow sight loss in elderly

... preserved the macular pigments, slowing down the progression from early AMD to late AMD. In contrast, the macular pigments of participants in a placebo group declined steadily. Dr Chakravarthy added: "These findings are important because this is the first randomised controlled clinical trial to ...

Preventing ear infections in the future: Delivering vaccine through the skin

... Animals that received the vaccines were able to very rapidly reduce, or completely eliminate NTHi from the nose and ears, but animals that received a placebo did not. ...

Cocaine: Perceived as a reward by the brain?

... its response to addictive drugs. This study was carried out in ten non-addicted users of cocaine, all of whom sniffed cocaine on one test day and placebo powder on another. Participants underwent blood tests before and after taking the drug, and dopamine release in the brain was measured using PET ...

After a few drinks, older adults more impaired than they think

... comparison group aged 25 to 35 who had at least one drink a month. Within each group, some individuals were given alcohol while others were given a placebo beverage that did not elevate their breath alcohol levels. The groups were carefully matched by gender, body mass index, history of alcohol ...

1 drug may help people both lay down the drink and put out the cigarette

... both disorders" according to McKee. McKee said that 80% of participants receiving varenicline did not take a drink at all, compared to 30% of the placebo group. The findings suggest that varenicline has the potential to be at least as effective in reducing drinking as naltrexone, another drug found to ...

Vitamins C and E and beta carotene again fail to reduce cancer risk in randomized controlled trial

... beta-carotene. With an average of 9.4 years of follow-up time, there was no statistically significant benefit from antioxidant use compared with placebo in terms of disease risk or mortality due to cancer. Overall, 624 women developed cancer and 176 died from cancer during the follow-up time. Compared ...

Calcium and vitamin D may not be the only protection against bone loss

... of the diet may attenuate bone loss in healthy older adults." In this study, 171 men and women aged 50 and older were randomized to receive placebo or doses of either: potassium bicarbonate, sodium bicarbonate, or potassium chloride for three months. Researchers found that subjects taking ...

Coping and copulation behavior may help calculate diabetes risk

... in their behavioral traits and native environment. During their tests, they discovered that merely handling the male mice and subjecting them to a placebo test where glucose was replaced with saline resulted in significant differences in blood sugar levels. Males of a calmer, more monogamous species ...

Positive results in Phase 2 trial of treatment of C-difficile-associated diarrhea

... 200 patients symptomatic with CDAD receiving standard of care antibiotics (metronidazole or vancomycin) were randomized to receive either intravenous placebo or intravenous administration of a combination of MDX-066 (CDA-1) and MDX-1388 (CDB-1), two fully human antibodies that neutralize C. difficile ...

Optimal dose of vitamin E maximizes benefits, minimizes risk

... studies of the benefits of vitamin E is the Women's Health Study, in which 40,000 healthy women, 45 and older, took 600 IU vitamin E supplements or a placebo every other day for 10 years. Women taking the supplements had 24 percent fewer deaths from heart disease. Vitamin E's protective effect appeared ...

New cardiology research presented at CHEST 2008

... randomized 405 patients with PAH, of whom 53 percent were taking concomitant bosentan, to two study arms. The groups received either tadalafil or placebo orally once daily as monotherapy or as add-on therapy to bosentan. Compared with placebo, tadalafil, 40 mg, increased 6-minute walk distance, delayed ...

Is yakult helpful in the treatment of irritable bowel syndrome?

... transit and therefore, in order to confirm the effect of Yakult(R) on SIBO, future studies will include monitoring of transit time in addition to placebo control. A research article to be published on August 28, 2008 in the World Journal of Gastroenterology addresses this question. The research ...

Common treatment to delay labor decreases preterm infants' risk for cerebral palsy

... Maternal Fetal Medicine Units Network, enrolled 2,241 women between Dec.1997 and March 2004. The women were randomly assigned to receive either placebo or magnesium sulfate. They all had similar characteristics, including gestational age (24 to 31 weeks) at randomization and risk factors for preterm ...

Ikaria(R) Receives FDA Orphan Drug Designation for Inhaled Carbon Monoxide for Delayed Graft Function in Solid Organ Transplants

... as part of our overall goal of delivering new therapies for the underserved critical care market." Ikaria is currently conducting a single-blind, placebo controlled, dose-escalating Phase 2 study of inhaled carbon monoxide in patients receiving renal transplants. The primary endpoint of the study is ...

UT Health Science Center researchers study diet and autism

... will be taken off gluten and dairy products before the four-week study and then half will be given gluten/milk powder and half will be given a placebo powder. Researchers will study intestinal permeability (leaky gut) through urine collection and behavior through psychometric testing. ...

Ikaria(R) Receives FDA Orphan Drug Designation for Inhaled Carbon Monoxide for Delayed Graft Function in Solid Organ Transplants

... as part of our overall goal of delivering new therapies for the underserved critical care market." Ikaria is currently conducting a single-blind, placebo controlled, dose-escalating Phase 2 study of inhaled carbon monoxide in patients receiving renal transplants. The primary endpoint of the study is ...