personalized

Affymetrix and the Karolinska Institutet Announce Translational Medicine Strategic Alliance

...ager and Vice President, Affymetrix. "This is what personalized medicine is all about -- enabling clinicians to detect diseases earlier and manage them more effectively. We are excited about the potential of this agreement to move the translational medicine field forward." Karolinska Institutet agreement is part...

Vascular structure and function improve with diet and exercise

...eks." Researchers studied the combined effects of personalized physical exercise and Mediterranean-style diet plans in volunteers with pre-clinical risk factors for cardiovascular disease. The study reported preliminary data from the larger randomized Staged Nutrition and Activity Counseling (SNAC) trial. A Med...

Affymetrix Licenses Microfluidics Technology From Caliper Life Sciences

...d is pioneering areas such as pharmacogenomics and personalized medicine. Incorporating our technologies -- first laboratory automation and now the potential for Caliper's microfluidics technologies -- into these vital areas of human health is important to our corporate ideals and to our future as a key technolog...

FDA Works To Speed The Advent Of New, More Effective Personalized Medicines

...c the opportunity to hear about the science behind personalized medicine, an issue of critical importance to both consumers and FDA. Presentations will be from experts in the field and there will be time for questions. For more information ; for public session . ...

Affymetrix and bioMerieux Extend Their Agreement on GeneChip(R) Technology to Breast Cancer Diagnostics

...pplication will be vast, ranging from diagnosis to personalized treatment," explained Dr Christophe Merieux, Vice President Research and Development - Medical Affairs. ...

Whole genome promoter mapping - Human Genome Project v2.0?

...arkers for diagnosis and prognosis, or determining personalized therapies, so-called pharmacogenetics, but we don't know how these genes are regulated or even related to each other. The identification of such a large number of promoters means that we can begin to answer these sorts of questions." ...

Science's Breakthrough of the Year: Watching evolution in action

...isease, and may lay the groundwork for a future of personalized genetic medicine. This year's sequencing of the 1918 pandemic flu virus could have a more immediate impact on medicine. The amazing story of flu genes preserved in permafrost and painstakingly reconstructed has a chilling coda: the deadly flu seems ...

ASU researchers 'wire' DNA to identify mutations

...ions for cancer research or future applications in personalized medicine," said Zhang, an associate research professor of the Center for Single Molecule Biophysics in the Biodesign Institute at ASU. "Currently, the main issue in doing this type of detection is that it is still costly and time consuming." The t...

Carnegie Mellon develops non-invasive technique to detect transplant rejection at cellular level

... this advance will allow doctors to provide highly personalized care that could prevent transplant rejection." Organ transplantation is the preferred clinical approach to treat end-stage organ failure, but transplant patients face a lifetime of immunosuppressive therapy and the risk of losing the new organ due t...

BiovaxID?yields 89 percent survival in patients with aggressive non-Hodgkins

...of surviving 5 years. BiovaxID, an investigational personalized anti-cancer vaccine, stimulates the immune system to seek out and destroy tumor cells. The data were published in a recent edition of Nature Medicine (Nat Med.2005; 11(9):986-91). In this single-arm, open-label Phase 2 clinical study, patients wit...

UCLA scientists uncover mechanism of response to targeted therapy

...ature Medicine, takes researchers a step closer to personalized medicine - treating cancer patients not with a one-size-fits-all therapy but with a treatment based on the specific molecular signature of their cancer cells. "We knew there were certain kidney cancer patients who responded to this drug, but we didn...

Two NIH initiatives launch intensive efforts to find roots of common diseases

...cally advanced measures of dietary intake, precise personalized measures of physical activity, and biological measures that identify prior exposures to potential toxins such as metals and solvents. NIH also will assess disease indicators like inflammation and oxidative stress that are known to be influenced by en...

Potential heart benefit found in stem cells

...s of medical research today. While the promise of personalized medicine and effective treatments for debilitating diseases drive progress in this area, moral and ethical dilemmas about embryonic cells continues to cloud the field. In research presented today at the American College of Cardiology's 55th Annual S...

Tetracycline plus teeth equal gray smile

...d not afford such costly treatment. He developed a personalized treatment plan for the patient, which allowed him to significantly alter the shade of his patient's teeth, without the costly procedures. Dr. Capehart's new tooth whitening treatment protocol involves placing the patient on a prescription dose of ...

Synthetic molecule causes cancer cells to self-destruct

...otentially offers an effective method of providing personalized anti-cancer therapy.Most living cells contain a pr...of procaspase-3 found in their tumor cells." Such personalized medicine strategies are preferential to therapies that rely on general cytotoxins, the researchers s...

New GI technologies improve internal organ visualization

...ver sedation during surgery with computer assisted personalized sedation (CAPS), which uses computer software to facilitate precise control of drug delivery. Anesthesiologists and physician/nurse care teams in the study first injected 24 patients (12 colonoscopy and 12 endoscopy) with a single dose of fentanyl...

New strategy rapidly identifies cancer targets

In a step toward personalized medicine, Howard Hughes Medical Institute investig...ncer will respond to ?a critical step in achieving personalized medicine. Four cancer drugs that inhibit tyrosine kinases are already on the market, including Gleev...

First-ever genomic test predicts which lung cancer patients need chemotherapy to live

...py. "This new genomic test is a clear example of personalized medicine, where we use the unique molecular characteristics of each patient's tumor to guide treatment decisions," said Geoffrey Ginsburg, M.D., Ph.D., a professor of medicine and co-author of the study. Eventually, physicians will use genomic test...

Large-scale genomics project will hunt genes behind common childhood diseases

...o a patient's genetic profile represents an era of personalized medicine still in its early stages. Part of the research task ahead, said Dr. Hakonarson, is not only to map gene variants to disease risk, but also to investigate how genes interact with environmental factors. "We will be tracing the major underly...

Patients to benefit from novel technology revolutionizing high-speed molecular imaging

...detectors--this new technology can open the way to personalized diagnostics taking into account patient-specific p...tton. Patients receive a lower radiation dose, and personalized scanning takes into account unique patient physiology and anatomy, he added. "Simultaneous imaging o...

New test helps identify hepatitis C patients at high risk of developing cirrhosis

...sease that is ushering in the long-promised era of personalized medicine based on each individual's genetic makeup. The Stanford group was one of the five sites that helped determine that the genetic test can identify patients who are at high risk of developing cirrhosis from chronic hepatitis C infection. Th...

Susceptibility to Crohn's disease -- an important new clue

...dical genetics, potentially paving the way towards personalized medicine and drug target identification. ...

Gene expression test reveals ER and HER-2 status of breast tumors

...logy tests. "This is one important step towards personalized diagnosis and treatment planning based on an integrated genomic test of an individual tumor," said senior author W. Fraser Symmans, M.D., associate professor in the M. D. Anderson Department of Pathology. The Lancet Oncology paper results are the lat...

Rapid, Low-Cost DNA Testing

... "This could be very important for applications in personalized medicine where a particular DNA sequence will be linked to a prescribed therapy. In fact, we see this happening already." ...

Genetic factors are linked to fever following smallpox vaccination

...rding to risk. This type of practice, the goal of personalized predictive medicine, appears closer in feasibility than ever given the pace of genetic testing.”...

Blood test may help signal tumor's remission, return in throat cancer patients

...cellent example of the predictive, preemptive, and personalized approach to medicine that the NIH strives for.” Roughly 20 years ago, the primary method for treating throat cancer was to surgically remove the tumor. Because this treatment can severely impair a patient’s quality of life by damaging voice, speec...