Overdose in Biological News

Unique pattern of gene expression can indicate acetaminophen overdose

... accurate new tools to detect acetaminophen overdose in humans. overdose of acetaminophen, the active ingredient in many ... seek emergency room treatment for acetaminophen overdose each year. The research published online this ...

Ocera Therapeutics licenses novel treatment for acute hepatic encephalopathy from UCLB

... cirrhosis patients in the U.S. Acute liver failure is a life threatening condition in otherwise healthy patients and is most commonly caused by an overdose of paracetamol (acetaminophen in the U.S.). Other causes include reactions to other drugs, herbs, or acute hepatitis. AHE is one of the common ...

ACS PressPac -- Sept. 17, 2008

... often mix it with chalk, flour, or other "cutting agents." Because heroin users do not know the exact purity of the drug, they are more at risk for overdose and even death. Conventional tests for determining the purity of street heroin involve destructive and time-consuming sample preparation, the ...

American Chemical Society's Weekly PressPac -- Sept. 10, 2008

... times faster than the body's natural version of BChE, the scientists say, noting that reducing levels of the drug in the blood is a key to fighting overdose in humans. The substance also prevented convulsions and death when injected into mice that were given overdoses of cocaine, they note. MTS ...

Codeine not safe for all breastfeeding moms and their babies

... compatible with breastfeeding. Following numerous reports through the Motherisk counseling service and the tragic death of an infant who died from an overdose of morphine acquired from breast milk, Koren and his team, located at SickKids and The University of Western Ontario, investigated these ...

Common treatment for methamphetamine overdose may damage brain cells

... used in emergency rooms to treat methamphetamine overdose damages nerve cells in an area of the brain known ... that a standard treatment for methamphetamine overdose in humans might worsen drug abuse-related brain ... who have been treated for a methamphetamine overdose to seizures and the development of movement ...

Glucose triggers brain cell death in rats after hypoglycemic coma

... is broken down and used for energy. Diabetics do not produce enough of their own insulin and must take it several times a day. A severe insulin overdose can reduce levels of glucose in the blood to extremely low levels –?a condition known as hypoglycemia –?and cause hypoglycemic coma, resulting in ...

Bird sex is something else

... But research published today in the Journal of Biology shows that birds are extraordinary, because some bird genomes can live with an apparent overdose of sex-related genes. US researchers Itoh, Melamed et al. working in Arthur Arnold’s University of California, Los Angeles laboratory used RNA ...

Breathing easy: When it comes to oxygen, a bug's life is full of it

... The drawback is that, when they are at rest, this level of oxygen is toxic, he has theorized. Insects close their spiracles during rest to avoid an overdose of oxygen, which can result in the production of free radicals which cause tissue damage, he has said. His work could have applications to insect ...

High-tech research shows cocaine changes proteins and brain function

... than a "flashlight," he said. Hemby and his colleagues analyzed thousands of proteins from brain tissue obtained from individuals who died of cocaine overdose and compared these "protein profiles" with individuals who died of non-drug related causes. "The findings provide new insights into the long-term ...

High resolution 'snapshots' detail dynamics of a cocaine antibody

... to be a major public health problem, so far eluding efforts at developing an effective therapeutic agent to counter the craving, addiction, and overdose of the drug. To date, no treatment has been approved by the Food and Drug Administration (FDA). Commenting on the new findings, Xueyong Zhu, ...

Prescription pain patch abuse blamed for increase in deaths

... painkiller for a quick and dangerous high, University of Florida researchers warn. The trend is raising alarm as the number of people dying from an overdose of the drug fentanyl, an opioid 100 times more potent than morphine, rises. Addicts are misusing a clear patch that transfers a controlled dose of ...

Some Brain Cells Change Channels

... of channel that keeps calcium out. If muscle-controlling nerve cells can do the same thing, forcing the swap might help protect them from a calcium overdose that can kill them in Lou Gehrig's disease. "We don't know yet whether this happens in muscle-controlling nerve cells, but we're looking into it," ...

Some Brain Cells 'Change Channels' To Fine-tune The Message

... of channel that keeps calcium out. If muscle-controlling nerve cells can do the same thing, forcing the swap might help protect them from a calcium overdose that can kill them in Lou Gehrig's disease. "We don't know yet whether this happens in muscle-controlling nerve cells, but we're looking into it," ...