Organ in Biological News

Fate in fly sensory organ precursor cells could explain human immune disorder

... about the Notch signaling pathway in sensory organ precursor cells in the fruit fly could explain ... two daughter cells arise from a single sensory organ precursor mother cell. Among the daughter cells, ... same mother cell. Thus the fruit flies sensory organ precursor cell division has been used as a model ...

GARP makes the difference

... them to inhibit unwanted immune reactions such as organ rejection. Their results have now been published ... also turn into a problem, for example after an organ transplant. The immune system recognizes the new organ as "foreign" and starts fighting it. In the end, ...

University of Florida study provides insight into evolution of first flowers

... said. Advanced angiosperms have four organ types: female organs (carpels), male organs ... structures. The researchers expected each type of organ found in Persea's flowers would have a unique set ... they found significant overlap among the three organ types. "Although the organs are developing to ...

World premiere in stem cell research in Montreal

... use in adults," Dr. Sauvageau affirmed. organ transplants without side effects: the medicine of ... medications against rejection of the transplanted organ and suffer the side effects for the rest of their ... by bone marrow attack the transplanted organ as if it were an invader. By extrapolation from ...

Children's National research links platelets to sepsis-related organ failure

... identified a previously unknown contributor to organ failure in patients suffering from sepsis: ... cases are fatal, and in most, the resulting organ failure, not the underlying infection, is the ... that this factor may be a major contributor to organ failure. Granzyme B was only detected in humans ...

From stem cells to new organs: Stanford and NYU scientists cross threshold in regenerative medicine

... on which stem cells can form a 3-dimensional organ and transplant rejection. "The ability to ... mature cells could revolutionize the field of organ transplantation," said Geoffrey Gurtner, M.D., ... cells had been coaxed into becoming an organ, the organ would have "taken hold" in the animal's body. In ...

Researchers explore new driver of transplant rejection: Platelets

... responses that play a critical role in organ transplant rejection, according to a new report ... immune response that can trigger or exacerbate organ rejection. Not only do they rush to the scene of ... to do, Morrell says, but in the context of organ transplants, their pro-inflammatory function gets ...

Single gene lets bacteria jump from host to host

... bacterium to create a predator-fooling light organ and a fish that uses a different strain of the ... one strain of the bacterium forms a light organ that mimics moonlight and acts like a cloaking ... another strain of the bacterium colonizes a light organ within the animal's jaw and helps illuminate the ...

Embryonic stem cells might help reduce transplantation rejection

... has implications for possible improvements in organ and bone marrow transplantation for humans. The ... . People who need bone marrow or solid organ transplantation must take immunosuppressive drugs ... system to make it receptive to the eventual organ or bone marrow donor's genetic make-up," said ...

Battling diabetes with beta cells

... alternative forms of treatment in cases in which organ transplantation is not an option. And one day, ... eventually require extreme measures, such as organ transplants, to stay alive. "The shortage of organ donors makes the development of new cell sources ...

How 'secondary' sex characters can drive the origin of species

... biologists believe changes in copulatory organ size and shape can spur speciation by making ... they observed in O. taurus's horn and copulatory organ size must have occurred over an extremely short ... are led to believe, variation in male copulatory organ size within species tends to be very low, humans ...

Caution on stem cell therapy

... SALT LAKE CITY A single organ may contain more than one type of adult stem cell ... cells that can become any type of cell in the organ in which they are found. Medical researchers hope ... any kind of cell in the body not just in a given organ and are obtained from test-tube fertilization of ...

Bees disease -- 1 step closer to finding a cure

... of a bacterium called Paenibacillus larvae in the organ cavity of honey bee larvae. The accepted view was ... make holes in the gut wall and enter the larval organ cavity, the presumed primary place of bacterial ... that the bacteria burst out of the gut into the organ cavity thereby killing the larvae. These findings ...

Early exposure to common weed killer impairs amphibian development

... during an often overlooked period of development, organ morphogenesis. Study Results Broadens ... Herbicide's Effects During a Vulnerable Stage organ morphogenesis is a brief, extremely sensitive ... the consequences of atrazine exposure during organ morphogenesis, McLaughlin and her colleagues, ...

Immunosuppressant further linked to birth defects

... . Approximately 14,000 births to organ transplant recipients, primarily kidney ... the first year of a transplant, provided that organ rejection or other complications have not ... is a required, life-long treatment for solid organ transplant recipients. They are used to prevent, ...

Northwestern Memorial trial may wean kidney transplant patients off antirejection drugs

... transplant surgery, anti-rejection drugs for the organ recipient are a must, but with prolonged use can ... Northwestern Memorial Hospitals department of organ transplantation to enroll qualifying subjects in ... and an HLA compatibility test is performed before organ transplantation to find out if tissues match ...

USC researchers identify mechanism that controls activation of stem cells during hair regeneration

... the regulation of hair re-growth and ultimately organ regeneration." The hair is an important model for organ regeneration in mammals because it is one of the ... hair cycling as one of the mainstream models for organ regeneration. However, most of these works focus ...

Scientists uncover how hormones achieve their effects

... cells form a projection that serves as a mating organ and brings about the fusion of two cells. The ... changes that underpin the formation of the mating organ and the fusion of the cells. Scientists in the ... is very high at the tip of the developing mating organ and then gradually gets less towards the centre ...

Sea cucumbers fast track organ regrowth by healing their wounds

... Sea cucumbers are the champions of organ regrowth because they direct their wound healing ... cellular mechanisms during wound healing and organ regeneration gives us the opportunity to discover ... the healing processes found in animals capable of organ regeneration. So it remains to be seen at a ...

Enigmatic sea urchin structure catalogued

... that the approach of combining all structural data available on a given organ in combination with a broad taxonomic coverage can yield novel insights into the evolution of internal organ systems. Alexander Ziegler, from Charit-Universittsmedizin Berlin, led ...

REGiMMUNE presents enhanced efficacy data in preclinical transplantation models

... "The study not only demonstrated the efficacy of RGI-2001 in solid organ transplants; it showed the potential of RGI-2001 to induce ... tolerance is expected to provide significant clinical benefits in organ transplantation and bone marrow transplantation. The REGiMMUNE study ...

MCG researcher among first to receive NIH stimulus funding

... high risk for the disease. "Studies have shown that cocaine can affect organ function, but the specific effect on renal function has not been ... for this patient population by making them increasingly susceptible to organ failure, especially after trauma. "Many people who are involved in ...

Research could lead to new non-antibiotic drugs to counter hospital infections

... now. Scientists have long known that after an operation or organ surgery, levels of inorganic phosphate fall. The authors of the PNAS ... of antibiotics and disease-fighting white blood cells, they find it inside organ tissues. This process damages and sometimes even kills their host. ...

Human adult testes cells can become embryonic-like

... stem-like cells, and they have done this work using testis tissue from organ donors, which they say has provided enough valuable tissue to allow them ... research team conducted the study using testes donated to GUMC from four organ donors, aged 16-52 years old. "This is novel data which strengthens ...

Gene mutation increases drug toxicity, rejection risk in pediatric kidney transplants

... risk for side effects, including compromised white blood cell count or organ rejection, according to new research. Published online Feb. 18 by the ... is an immunosuppressive agent commonly used to prevent rejection in organ transplants, particularly in kidney transplants. After taken orally, the ...

Texas Medical Center researchers win collaborative grants

... to selectively stimulate neurons of interest noninvasively within an organ could be used as the basis for neural prosthetic development in many other organ systems, such as the brain, spinal cord, eye and peripheral nerves." ...

Cold Spring Harbor Protocols features organ and cell culture methods

... provides "Preparing Recombinant Gonad organ Cultures." It can be useful to assay migration between any two adjacent ... developing gonad and kidney using tissue recombination, combined with an organ culture technique. This method is freely accessible on the website for ...

Researchers find an essential gene for forming ears of corn

... Eudicots vs. Monocots Much has been learned in the past about organ development in the cress plant known as Arabidopsis , which biologists ... as monocots. The spi1 gene has cousins that affect auxin synthesis and organ formation in Arabidopsis, but there are important differences. "In ...

Ikaria(R) Receives FDA Orphan Drug Designation for Inhaled Carbon Monoxide for Delayed Graft Function in Solid Organ Transplants

... tissue, leading to an inflammatory response that could result in poor organ function. In the United States, approximately 28,000 patients received a solid organ transplant in 2007. Orphan drug designation provides an accelerated FDA ...

Ikaria(R) Receives FDA Orphan Drug Designation for Inhaled Carbon Monoxide for Delayed Graft Function in Solid Organ Transplants

... tissue, leading to an inflammatory response that could result in poor organ function. In the United States, approximately 28,000 patients received a solid organ transplant in 2007. Orphan drug designation provides an accelerated FDA ...

American Chemical Society's Weekly PressPac -- July 16, 2008

... IMMEDIATE RELEASE "Snow flea antifreeze protein" could help improve organ preservation Journal of the American Chemical Society Scientists in ... making it potentially more effective than the native form for use in organ and tissue preservation, the scientists note. "Our most significant ...

Researchers discover link between organ transplantation and increased cancer risk

... PHILADELPHIA Researchers have determined a novel mechanism through which organ transplantation often leads to cancer, and their findings suggest that ... to a transplanted organ, helping it survive and thrive. "But once the organ has stabilized, it may be possible to lower the level of VEGF expression ...

Gaining ground on sickle cell disease

... diseasewith some patients experiencing frequent, severe pain crises and organ damage, while others are scarcely aware of their disease. "Our study ... and can block the smaller vessels, resulting in severe pain and eventual organ damage as tissues are robbed of their blood supply. The sickle-shaped red ...

Pitt receives $2.5 million to simulate and analyze brain, immune system activity

... the researchers want to pinpoint the origin of such conditions as multiple organ dysfunction syndrome (multiple organ failure), a potentially deadly, uncontrollable inflammation that usually ...

Scientists find stem cells for the first time in the pituitary

... to identify candidate cells in the anterior pituitary, the section of the organ that secretes hormones. They then used other techniques to show that these ... appeared later. They speculate that having two sets of cells may let the organ respond differently to changing body conditions. Dr. Enikolopov notes that ...

Dinosaur from Sahara ate like a 'mesozoic cow'

... the dinosaurs braincase. There, small canals of the brains balancing organ revealed the habitual pose of the head. Reconstructed from CT scans, these ... Lawrence Witmer, professor at Ohio University, who imaged the brain and organ of equilibrium, said, What we have here is the first good look at a ...

HGS announces positive Phase 2 LymphoStat-B at ACR meeting

... percentage of serologically active patients who experienced no new BILAG A organ flare and no more than one new BILAG B organ flare (92% at Week 52; 94% at Week 128). A sustained improvement in ...

Controlling for size may also prevent cancer

... Hopkins recently discovered that a chemical chain reaction that controls organ size in animals ranging from insects to humans could mean the difference ... of molecular biology and genetics. The good news is that maybe all organ growth can be reduced to this one chemical event on the Yap protein but ...

Presence of gene mutation helps guide thyroid cancer treatment

... in the lymph node due to metastasis (the transfer of tumor cells from one organ or part of the body to another organ or part) and higher stage cancer. In patients with conventional PTC, ...

Advance in effort to fight malaria by tricking the mosquito's sense of smell

... By mapping a specialized sensory organ that the malaria mosquito uses to zero in on its human prey, an ... the most prevalent life-threatening disease in the world. The sensory organ is the maxillary palp. It is one of three structures extending from the ...