Node in Biological News

Study provides insight on a common heart rhythm disorder

... fatal human heart rhythm disorder called sinus node disease. Also known as "sick sinus syndrome," the ... into cellular mechanisms that regulate sinus node function and identifies an unanticipated new ... therapies to regulate more common forms of sinus node disease. The findings, which also have research ...

Breast cancers behave differently before and after the age of 70

... has been conflicting evidence on aging and lymph node involvement and this study is the first to show ... sites in the body. The effect of age of lymph node positivity is not straightforward. There seems to ... age appears to have a negative effect on lymph node status the older they become, the less likely ...

Lymph nodes can be key in spreading prion infectivity

... While we can show that the regional lymph node plays no pivotal role in the neuroinvasion of ... in hamsters. The team discovered that if a lymph node close to the site of infection is removed within ... still develops the disease. However, if the node is removed 4 weeks before infection, a high dose ...

Presence of gene mutation helps guide thyroid cancer treatment

... a higher rate of cancer formation in the lymph node due to metastasis (the transfer of tumor cells ... the mutation was associated with older age, lymph node and other metastasis, and was an independent risk ... to surgery, such as removing the central lymph node along with the diseased thyroid, to avoid the ...

New supercomputer to reel in answers to some of Earth's problems

... EMSL. Chinook has 4620 Quad-core processors built into 2310 nodes. Each node can be thought of as the equivalent of four personal computers. But Chinook's nodes are more like supercharged PCs: the Quad-cores give each node the equivalent of eight processor-cores and 32 gigabytes of memory. ...

DEIMOS joins MARS and its satellite of instruments on seafloor

... MARS, which stands for Monterey Accelerated Research System, consists of a node the size of two compact cars that serves as both a power strip and a ... feet below the surface in Monterey Bay. Most recently connected to the node is the University of Washington-designed DEIMOS, which stands for ...

Neurotechnology Announces MegaMatcher 2.1 SDK for Development of Large-scale AFIS and Multi-biometric Face-Fingerprint Identification Systems

... tolerance functionality when the system is used in a cluster. If a cluster node faults, MegaMatcher 2.1 automatically passes the content to other nodes, ... requiring re- initialization. This virtually eliminates down-time due to node failures, makes the system more reliable and helps to ensure non-stop ...

Controlling embryonic fate by association

... and carry out their tasks in the cell. A special complex called node (Nanog and Oct4-associated Deacetylase) contains a critical component called Mta1 along with histone deacetylases. node associates with Nanog and Oct4 to control the fate of embryonic stem ...

Argonne National Lab acquires first SiCortex SC5832

... usage while providing industry leading performance. A SiCortex cluster node consumes 15 watts of power, an order of magnitude less than the 250 watts ... concept in high-performance computing by implementing a complete cluster node on a chip, including six 64-bit processors, multiple memory controllers, a ...

'Green' energy from algae

... built on the northern KIT campus, with the favorable conditions in terms of space and infrastructure being made use of. "This will represent a major node in the presently rather rapid networking of algae biotechnology", emphasizes Posten. To make energy production from algae economically efficient, it ...

Researchers design first model motor nerve system that's insulated and organized like the human body

... Ranvier act like power station relays along the myelin sheath. They chemically boost signals, allowing them to get across breaks in myelin, or from node to node, at the electrically charged nodes of Ranvier. Nerve malfunctions, called neuropathies, involve a breakdown in the way the brain sends and ...

Towards a natural pacemaker

... the heart rate biologically could be a much better solution, but there are some major hurdles. The way electrical signals are generated in the SA node and hence the heart rate are far from simple. There are three separate electrical pathways between cells, called HCN or 'funny' channels (because ...

Collaboration leads to success: Most powerful computer of its kind in western N.Y. available worldwide

... MCIL worked on platforms for monitoring grid systems, for providing a single point-of-entry portal and for solving intricate problems involving node swapping, predictive scheduling and resource management. MCIL has been responsible for grid-enabling critical applications in areas such as ...

UC Davis researchers identify a protein that may help breast cancer spread, beat cancer drugs

... Carraway, senior author of the study, knew that Muc4 was not always expressed in primary breast cancer tumors, yet it could be present in lymph node metastases. He suspected that it may have a specialized function in the process of metastasis. "Breast cancer deaths are caused by metastasis, not ...

New origin found for a critical immune response

... had much lower accumulation of monocyte-derived dendritic cells and TH1 responses. The scientists concluded that there is a blood-derived lymph node dendritic cell type that has a key role in developing acute T-cell responses. "For so long, dendritic cells from tissues were the obvious answer," ...

New technique for cancer screening

... vast tissue resource. Balic and colleagues will now evaluate the ability of HRM-based DNA methylation analysis to predict the presence of lymph node metastases and to detect very small tumor deposits in lymph nodes with known micrometastatic disease in a well defined cohort of prostate cancer ...

Novel technique changes lymph node biopsy, reduces radiation exposure

... the invention of super-depth photoacoustic microscopy, and Xia's lab invented the gold nanocages. Their work can minimize invasive surgical lymph node biopsy procedures to determine if breast cancer has metastasized and reduce the patient's exposure to radioactivity. The nanocages also have the ...

Novel technique changes lymph node biopsy, reduces radiaiton exposure

... the invention of super-depth photoacoustic microscopy, and Xia's lab invented the gold nanocages. Their work can minimize invasive surgical lymph node biopsy procedures to determine if breast cancer has metastasized and reduce the patient's exposure to radioactivity. The nanocages also have the ...

Acoustical Meeting, Nov. 10-14, 2008 in Miami, Florida

... by parabolic reflectors, which also record the return echo. As many as 12 reflectors pointing in different directions can be mounted together as a node on a pier or bulkhead. The SDSN strategy is less expensive and more effective than other swimmer detection techniques that use phased arrays, says ...

San Diego Supercomputer Center and UCSD announce 'Triton Resource'

... specifications call for it to contain numerous large-memory or "fat" nodes, and multiple connections to storage. Using this architecture, a single node should be filled in about 60 seconds, so that large-scale data sets can quickly and easily be brought into memory, manipulated, and written out to ...

8 National Medals of Science awardees to be honored at gala, then the White House

... theory of data networks. This was a decade before the birth of the Internet which occurred when his host computer at UCLA became the first node of the Internet in 1969. He wrote the first paper and published the first book on the subject; he also directed the transmission of the first message ...

Is that song sexy or just so-so?

... were higher in the "breeding" females than the "non-breeding" ones. But the effects of estrogen were not identical in every region. "If every node in the network just responded more in the presence of estrogen, then we'd conclude that estrogen acts as an on-off switch," Maney says. "But what ...

$2 million computer will help unravel major medical ailments

... toward important discoveries in medical diagnoses and treatment at a much faster speed." The new device is expected to be a 256 dual quad-core node cluster computer with 1 petabyte of storage. A petabyte is a measure of digital information equivalent to 1 quadrillion bytes or 1,000 terabytes. (A ...

UCLA researchers locate and image prostate cancer as it spreads to lymph nodes

... reliable indicator that the patient will have a poor prognosis, with disease recurrence and progression likely. Accurately assessing pelvic lymph node involvement in patients is critical in planning their treatment, Wu said. Currently, physicians don't know if a treatment is attacking cancer ...

Killer whales, blind bats, discriminating dolphins, mating birds

... that just happened a second ago, and immediately 'drill down' on that event with an interactive signal-processing tool box." Each VoxNet node is a portable, self-contained processor with a small four-channel acoustic array. Using a distributed set of nodes, a forested habitat can be ...

How molecular muscles help cells divide

... composed of the protein actin. The filaments grow in random directions until they encounter another node, where myosin motors in the contacted node pull on the actin filament, bringing the two nodes together. However, the researchers found that each connection is broken in about 20 seconds. ...

PET/CT imaging proves golden for detecting cancer in children

... M.D., Professor in Nuclear Medicine at Johns Hopkins Medical Institutions in Baltimore, Md. In our study, we found that PET/CT can detect small lymph node lesions diagnosed as negative with conventional (or anatomical) imaging and deny the presence of active disease in soft-tissue masses ...

UC Davis researchers move biotechnology closer to replacing electronic pacemakers

... his colleagues were able to reconstruct the SA node of the heart in pigs with implanted electronic pacemakers. The SA node is normally located on the right atrium, the ... heart rates in their patients. To restore the SA node function and evaluate the bioengineered cells, ...

APS lecturer shows rare video of 'teacher-student' immune cell interactions in live animal

... look at what happens inside a mouse lymph node when a foreign microbe enters the body. The ... "Before this, what had gone on inside the lymph node was largely a black box." His team published ... cells find each other once in the lymph node dendritic cells "educate" the T cells while in ...

Chemical guidance of T cells leads to immunologic memory and long-term immunity

... they encounter certain other cells in the lymph node that can activate them. The new research, ... T cells do not wander aimlessly through the lymph node but instead are steered towards areas in which dendritic cells concentrate. Think of the lymph node as a large airport terminal and the CD8+ T cells ...

Vitamin A's paradoxical role in influencing symmetry during embryonic development revealed

... the stage when the embryonic stem cells enter the node region of the embryo and begin forming the ... of the body. Cells in the vicinity of the node are instructed to behave differently depending on ... progress symmetrically. Belmonte compares the node to a doorway. "Before embryonic stem cells enter ...

How 'memory' T cells curb the spread of viruses throughout the body

... we found that memory CD8 T cells already killed target cells in the lymph node and decreased viral spread to the liver and spleen when the virus just ... disease partly because they curb the spread of the virus from the lymph node to vital organs at very early stages of the infection. “It’s like ...

HIV exploits competition among T-cells

... body. Moreover, because it takes 4-5 days for T cells produced in a lymph node to begin to leave it, the possibility exists to set up simultaneous, ... a separate winner for each strain is picked in each affected lymph node before immunodominance can come into play. "In our simulations, this ...

Scientists directly view immune cells interacting to avert autoimmunity

... laser-scanning microscopy, was able to focus deep within the lymph node of a diabetic mouse, allowing the researchers to show that immune cells ... try to boost or prevent immune responses. 'Clusters' of cells in a lymph node such as we have seen may be indicative of certain unbridled T cell ...

Agilent Technologies releases automated literature search tool for biology researchers

... can see and manipulate within Cytoscape. This network view includes a node represented by a geometric shape for each gene and protein, and links to indicate relationships. Each node includes hyperlinks to descriptions and articles relevant to that gene or ...

Migration alert -- How tumor cells home in on the lymphatic system

... which lymphatic vessels will be more effective routes for dissemination,” she explains. “Therapeutically, it indicates that a drug target for lymph node metastases could be blocking the signaling molecule or its receptor on the tumor ...

How the brain's backup system compensates for stroke

... stages of adaptive compensation for neuronal interference, the adult brain exploits pre-established patterns of functional specialization. When a key node in an information-processing circuit is impaired, healthy cortical networks can flexibly reconfigure processing in a way that is rapid, ...

Why doesn't the immune system attack the small intestine?

... Web site as an advanced online publication, investigators led by Shannon Turley, PhD, of Dana-Farber identify an unlikely group of peacemakers: lymph node cells that instruct key immune system cells to leave healthy tissue alone. The finding, which illuminates a previously unknown corner of the human ...

Pacific Rim researchers to collaborate on distributed bioinformatics analysis of avian flu

... while making any new software publicly available through open-source licenses. The funding to the University of Hawaii will allow it to become a node in the computational grid ?allowing it to access data for molecular-dynamics simulations using high-performance computing. "We need a better way to ...