Newborn in Biological News

Experimental treatment halts hypoxic-ischemic brain injury in newborns

... activator inhibitor-1 (PAI-1) into the brains of newborn rats, said Chia-Yi Kuan, M.D. PhD, senior ... the therapeutic effect of injecting PAI-1 into newborn rats suffering from the brain blood flow ... to the umbilical cord. Close to 20 percent of newborn children with hypoxic-ischemia die and 25 percent ...

American College of Medical Genetics affirms importance of newborn screening dried blood spots

... made in implementing broader and more consistent newborn screening since then and it is estimated that ... result of the expanded NBS. A critical aspect of newborn screening is the "dried blood spot, filter card" ... dried blood spots are vital to effective newborn screening across the United States," said Michael ...

How cold is too cold for newborn calves?

... the capacity of producers to protect their newborn calves. "The impact of weather on livestock is ... and lead time needed to take action to protect newborn livestock. The data collected helped create the Cold Advisory for newborn Livestock System (CANL). Beginning this month, ...

States expand newborn screening for life-threatening disorders

... eliminate the geographic gaps in the state newborn screening safety net. Now, whether babies are ... March of Dimes will maintain its watchdog role on newborn screening, said Dr. Howse, and will continue to ... nationwide, and to advocate for funding for the newborn Screening Saves Lives Act (P.L. 110-204). The ...

American College of Medical Genetics receives $13.5M NIH contract

... of Health (NIH) for the development of a National newborn Screening Translational Research Network. "This visionary contract will enable us to improve newborn screening, the care of patients identified in newborn screening, and our knowledge of the conditions ...

Newborn vitamin A reduces infant mortality

... "More studies are urgently needed to determine if newborn vitamin A supplementation would reduce mortality ... possible approaches for delivering vitamin A to newborn infants. In the 1980s, Alfred Sommer, MD, MHS, ... dose of vitamin A administered by mouth to a newborn child can save the lives of an additional 300,000 ...

Neural stem cell study reveals mechanism that may play role in cancer

... within the brains fluid-filled ventricles. These newborn neurons then migrate along the stem cell fibers ... neural stem cells. To our surprise, she says, the newborn neurons that the stem cells produced piled up on ... asymmetrical division, in which they produce one newborn neuron and one new neural stem cell. The ...

New evidence explains poor infant immune response to certain vaccines, says MU researcher

... why newborns contract infections easily. In his work, Zaghouani studied newborn mice and how their immune systems reacted when they were repeatedly ... and manifest in the form of allergic reactions. When Zaghouani gave the newborn mice an antigen shortly after birth, he noticed the presence of both Th-1 ...

M.I.N.D. Institute researchers call for fragile X testing throughout the lifespan

... Institute researchers have created an inexpensive spot blood test for newborn screening that is currently in clinical trials. Until testing for ... studies. They write: "These trials, if successful, make the case for newborn screening (for fragile X syndrome) more compelling and raise the prospect ...

Innovations in Pediatric Medicine CME conference brings together national pediatrics experts

... Medical Center and Weill Cornell Medical College 8:00 8:45 a.m. newborn Screening for Inborn Errors of Metabolism Dr. Piero Rinaldo, Mayo Clinic ... Nucleic Acids in Maternal Blood Provides Novel Opportunities to Improve newborn Care Dr. Diana W. Bianchi, Tufts University School of Medicine and the ...

No helicopter moms among Rutgers mutant mice

... known as stathmin or oncoprotein 18, motivates female animals to protect newborn pups and interact cautiously with unknown peers. This "fear gene" is ... the problem'. That's definitely not the kind of helicopter parenting that newborn mice need to survive, and by extension, the species needs to survive." ...

Salk researchers reprogram adult stem cells in their natural environment

... dentate gyrus of laboratory mice. Under normal conditions, the majority of newborn cells differentiated into neurons. When he introduced the Ascl1, which had ... and inhibitory neurons, he successfully redirected the fate of newborn cells from a neuronal to an oligodendrocytic lineage. "It was quite ...

Texas Hospital nation's first to use large-scale 'cocoon strategy' against whooping cough

... the nations first major cocoon strategy vaccination program to protect newborn infants from the life-threatening infection pertussis, more commonly known ... and adult family members who need it, helping protect the most vulnerable newborn and young infants, said Dr. Healy. At the same time, we will explore ...

Novel 3-D cell culture model shows selective tumor uptake of nanoparticles

... models of cancer cells for many years. Similarly thin brain slices from newborn rats can be cultured for weeks and are an important tool in brain biology. ... were labeled with fluorescent iron microparticles and grown on normal newborn rat-brain tissue slices. The double cell labeling technique allowed ...

Scientists link immune system's natural killer cells to infant liver disease

... experiment with a mouse model of biliary atresia. In the mouse experiments, the scientists used a rotavirus infection to induce biliary atresia in newborn mice. Similar to what was observed in diseased human infant livers, the researchers found that active NK cells were the most abundant cells ...

Skin-like tissue developed from human embryonic stem cells

... in the oral cavity. Within two weeks, tissues developed that were similar in structure to those constructed using mature cells derived from newborn skin, which are the current gold standard for tissue fabrication. "These engineered tissues are remarkably similar to their human counterparts and ...

Playing it safe

... with the work of Takashi Shinohara's team in 2004. The Japanese scientists discovered that, like embryonic stem cells, certain cells in the testis of newborn mice are able to develop into different kinds of tissue. In 2006, scientists working with Gerd Hasenfu and Wolfgang Engel in Gttigen reported that ...

Scientists discover new genetic immune disorder in children

... suggest that it may be present in about 1 in 6,300 births in this population. Because the mutation was found in three independent Dutch families, newborn screening for DIRA in this population, as well as that of northwest Puerto Rico, may be warranted, Dr. Goldbach-Mansky said. "The DIRA discovery ...

New guidelines to fight obesity in pregnancy issued

... birth is a serious health problem that costs the United States more than $26 billion annually, according to the IOM. It is the leading cause of newborn death and babies who survive an early birth often face the risk of lifetime health challenges, such as breathing problems, mental retardation and ...

Muscular dystrophy diagnosis delayed almost 2.5 years in boys

... and inexpensive blood test for any boy with symptoms and signs of motor delays and abnormalities could speed up the process while pilot studies on newborn screening are conducted. Recent University of Rochester Medical Center research published in the Journal of Pediatrics shows that boys who are ...

UTSA, Health Science Center collaborate with Merck & Co. to develop chlamydia vaccine

... infection. Long-term C. trachomatis infection in females can lead to pelvic inflammatory disease, ectopic pregnancy, serious complications for newborn infants and infertility. Macrolide (erythromycin-like) antibiotics can successfully eradicate the pathogen in most patients, but treated individuals ...

Early isolation linked to enhanced response to cocaine

... of drugs of abuse, such as cocaine. Rats were stressed: (1) as fetuses (by housing the pregnant mother alone), (2) as neonates (by isolating newborn rats for 1 hr daily during the first 9 days of life) or as adolescents (by housing each rat separately during days 21-35). Two additional groups: ...

Early isolation linked to enhanced response to cocaine

... of drugs of abuse, such as cocaine. Rats were stressed: (1) as fetuses (by housing the pregnant mother alone), (2) as neonates (by isolating newborn rats for 1 hr daily during the first 9 days of life) or as adolescents (by housing each rat separately during days 21-35). Two additional groups: ...

Amniotic fluid may provide new source of stem cells for future therapies

... this failure, such as using a low number of cells for the injection and conducting the transplant in adult mice (engraftment is easier to obtain in newborn mice). As additional confirmation of the probability that AFKL cells are indeed stem cells, the researchers examined them for the expression of ...

West Nile virus studies show how star-shaped brain cells cope with infection

... first identified the presence of West Nile Virus in New York in 1999. In this study, Lipkin and colleagues cultured astrocytes from the brains of newborn mice and exposed the cells to a West Nile virus-like molecule (called Poly I:C), either from outside or inside the brain cell membranes. After ...

Sihoun Hahn, M.D., Ph.D., FACMG is the 2009-2010 Luminex/ACMGF Award recipient

... testing and genetic services," said R. Rodney Howell, MD, FACMG, President of the ACMGF. Dr. Hahn is a member of the advisory committee for newborn screening in Washington state and the medical advisory committee for the Wilson Disease Association. He is Director, Biochemical Genetics Program ...

Synthesizing the most natural of all skin creams

... after nine months soaking in the womb, a newborn's skin is smooth unlike an adult's in the bath. While occupying a watery, warm environment, the newborn manages to develop a skin fully equipped to protect it in a cold, dry and bacteria-infected world. A protective cream called Vernix caseosa (VC), ...

Autism Speaks funds $5 million to studies on genetic and environmental risk factors for autism

... The project will enroll and follow up to 1200 mothers of children with autism at the start of a new pregnancy and document the development of their newborn siblings through age three. This groundbreaking study will provide a unique opportunity for studying possible autism environmental risk factors and ...

Crib-side studies help struggling newborns go home without feeding tubes

... they will develop them during their lifetime. The babies that learned to feed orally in the study did so through approaches developed at the newborn and Infant Disorders Program at Nationwide Children's Hospital. The program accelerates newborns' feeding skills through individualized, crib-side ...

Preterm birth: Magnesium sulphate cuts cerebral palsy risk

... shows. The findings of this Cochrane Review could help reduce incidence of the disabling condition, which currently affects around one in every 500 newborn babies overall, but up to one-in-ten very premature babies ( The neuroprotective function of magnesium in preterm babies was first suggested in ...

Cell 'anchors' required to prevent muscular dystrophy

... team was exploring the function of anchor protein ankyrin-B (ankB) by knocking out gene expression of the gene that makes the protein. They found newborn mice missing ankB had splayed shoulder bones, which stuck out of the animals' backs like wings, rather than lying flat, a symptom of a muscular ...

Repeat C-section before 39 weeks raises risk of neonatal illness

... 37 weeks later died or was diagnosed with a number of conditions, including respiratory distress syndrome and/or transient tachypnea of the newborn, newborn sepsis, seizures, necrotizing entercolitis, hypoxic ischemic encephalopathy, required ventilator support within 24 hours of birth, had umbilical cord ...

Control of blood vessels a possible weapon against obesity

... diseases like diabetes." Brown fat releases heat when it breaks down, and is mainly found in hibernating animals. In humans, it is found in newborn babies, but scientists believe by controlling blood vessel development that it might be possible to transform white fat to brown fat in adults as ...

Maternal health problems in Myanmar widespread

... senior author of the study and professor with the Bloomberg School's Department of Epidemiology. "Increased access to antenatal, labor delivery and newborn care services in eastern Burma is essential to improve the overall health status of these vulnerable populations. In addition, considerable ...

New scientific knowledge on juvenile diabetes

... study) was launched in Finland, supported by the Juvenile Diabetes Research Foundation International. Over a period of 14 years, more than 130,000 newborn infants have been screened for genetic risk and over 8000 at-risk children are being regularly followed. The research team was led by Prof. Matej ...

Persistent pollutant may promote obesity

... in water fleas through its effects on a receptor similar to the RXR. In addition, tributyltin causes the growth of excess fatty tissue in newborn mice exposed to it in utero. The effects of tributytin on RXR-like nuclear receptors might therefore be widespread throughout the animal kingdom. ...

Jupiter's shrinking red spot

... http://meetings.aps.org/Meeting/DFD08/Event/90049 7) MODELING EMBRYONIC HEART DEVELOPMENT Congenital heart diseases affect one percent of newborn babies and babies who are lost in the prenatal period, and the malformation of the circulatory system is responsible for 10 percent of stillbirths. ...

Animal and biological science highlights: San Antonio Fluid Dynamics Conference, Nov. 23-25

... http://meetings.aps.org/Meeting/DFD08/Event/89974 . 6) MODELING EMBRYONIC HEART DEVELOPMENT Congenital heart diseases affect one percent of newborn babies and babies who are lost in the prenatal period, and the malformation of the circulatory system is responsible for 10 percent of stillbirths. ...

The 'hole' story

... the female pelvis was found, evidence from the pelvis of a juvenile male led researchers to project that the cranial circumference and capacity of newborn Homo erectus babies was 30 percent smaller than more recent projections based on the newly discovered pelvis. Sileshi Semaw, a paleoanthropologist ...

The "hole" story

... the female pelvis was found, evidence from the pelvis of a juvenile male led researchers to project that the cranial circumference and capacity of newborn Homo erectus babies was 30 percent smaller than more recent projections based on the newly discovered pelvis. Sileshi Semaw, a paleoanthropologist ...