neck

New imaging method gives early indication if brain cancer therapy is effective, U-M study shows

...test the technique with breast cancer and head and neck cancer. In addition to Ross, U-M study authors are Bradford Moffat, Ph.D., assistant professor of radiology; Thomas Chenevert, Ph.D., professor of radiology; Theodore Lawrence, M.D., Ph.D., Isadore Lampe Professor and Chair of Radiation Oncology; Ch...

Pulsating ultrasound enhances gene therapy for tumors

... study--squamous cell carcinoma, found in head and neck tumors--is one of the least permeable cancers and does not respond well to chemotherapy or radiation. However, these types of tumors have responded to certain types of therapeutic genes. "This procedure is hypothetically generic for enhancing delive...

Biomarkers isolated from saliva successfully predict oral and breast cancer

..., disclosed similar predictive powers for head and neck cancers. "These results indicate that such biomarkers found in saliva, called salivary transcriptomes, can be exploited for robust, high-throughput and reproducible tools for early disease detection," said David T. Wong, professor and associate dean...

Turning viruses into allies against cancer

...with melanoma, 13 with breast, three with head and neck cancer, and two with colorectal cancer. Each patient, all in the later stages of their disease, received either a single injection of the virus, the volume depending on tumor size, or in later stages of the clinical trial, three injections separated ...

Penn Researchers Use Robotic Surgery

... of surgical robotics to the treatment of head and neck cancer and we've successfully devised novel approa...outh into the throat and voice box." For head and neck tumors, treatments often involve a combination of surgery, radiation therapy, and chemotherapy. In m...

Two new retroviruses—transmitted from animals—identified

... of surgical robotics to the treatment of head and neck cancer and we've successfully devised novel approa...outh into the throat and voice box." For head and neck tumors, treatments often involve a combination of surgery, radiation therapy, and chemotherapy. In m...

Scientists take aim at virulent bacteria by decoding machinery of key control enzyme

...re DNA molecule like fingers sliding down a guitar neck searching for the right chord, examining each base pair as it goes. Each time it finds the sequence GATC it stops and methylates the A nucleotide. Dam must move quickly, because if the bacteria reproduce with the wrong methylation pattern, gene expre...

Study shows how retinoic acid enters a cell's nucleus

... have shown that RA can help treat leukemia, head, neck and breast cancer. RA and its synthetic derivatives may also be useful in treatment of diabetes, arteriosclerosis and emphysema. Unfortunately, conventional treatments using RA require high, toxic doses, and tumors can develop resistance to the treat...

Scientists discover stem cell origin of neck and shoulders

... time the stem cell origin of the structure of the neck and shoulders in vertebrates. The scientists belie...stem cells making up the bones of the shoulder and neck and another making the muscles, a newly-discovered group of stem cells called mesenchymal stem cells...

Biased reporting found in cancer prognostic studies

...may predict the outcome of a patient with head and neck cancer. As researchers attempt to make sense of th...t the association between TP53 status and head and neck cancer mortality weakened as they expanded their analyses from the 18 published and indexed studies ...

New lead reported in tumor angiogenesis

...h factor, or HGF, and its role in helping head and neck tumors to turn cancerous. HGF does so, in part, by...hether, as they suspected, HGF stimulates head and neck tumor cells to release pro-angiogenic proteins. To their surprise, they found that was not the case....

Compound from Chinese medicine shows promise in head and neck cancer

...effectiveness of chemotherapy at treating head and neck cancer, researchers at the University of Michigan ... and swallowing. While new treatments in head and neck cancer have allowed some patients to undergo chemotherapy and radiation therapy instead of surgery, ...

Mass production of human papillomavirus could lead to gains against cervical cancer

...er types contribute to about a quarter of head and neck cancers and some skin cancers. A more common, less virulent form of the virus causes genital warts. Using the new technique scientists can quickly produce a thousand times more infectious virus per culture dish than they could using conventional met...

Scientists use stem cells to grow cartilage

...and reconstructive surgery. When removing head and neck cancers, surgeons often have to cut away parts of cartilage, and then take grafts from other parts of the body. With this new technique doctors would potentially be able to take stem cells from the patient, grow them in a laboratory, and then transpl...

Penn Surgeons Use Completely Robotic Surgery to Successfully Treat Prostate Cancer

...ars and is currently studying its use for head and neck cancer surgeries. “The robotic prostate program is a continuation of Penn’s commitment to finding and applying the most precise, most beneficial surgical techniques to put patients on a quicker road to recovery with better outcomes,?said Dr. Lee. ...

Scientists learn to predict protein-stabilizing ability of small molecules

...ars and is currently studying its use for head and neck cancer surgeries. “The robotic prostate program is a continuation of Penn’s commitment to finding and applying the most precise, most beneficial surgical techniques to put patients on a quicker road to recovery with better outcomes,?said Dr. Lee. ...

Common bacteria pirate natural mechanism to get inside cells

...namin, comes along and forms a necklace around the neck of that balloon, then chops it off," he says of the process that is ongoing with millions of receptors on the cell surface. "Adding nitric oxide to dynamin changes it from an inactive protein inside the cell to the active protein that mediates the f...

For one Stanford doctor, the beat goes on during open-heart surgery

...est, lifted the beating heart out, then craned his neck to the side, just so, searching for the right spot on the back of the heart to attach the next vessel. Ihnken, MD, clinical assistant professor of cardiothoracic surgery at the Stanford University School of Medicine, was using an innovative techniqu...

Basic research leads to a novel cancer therapy

... cancer, colon cancer, esophageal cancer, head and neck tumours, liver cancer, lung cancer, melanoma, ovarian cancer, pancreatic cancer, prostate cancer, and testicular cancer. The studies are in various stages of clinical trials (phases I through III), and most of them are being carried out in combinatio...

UF researchers develop ways to keep the bloom on the rose

...to wilting and failure of the flower to open. Bent neck typically occurs in the first three days after pur...s," Nell said. "As seen with the reduction of bent neck over the last five to eight years, the results of this research programs are making a difference wit...

A new way of looking at molecular motors

...er stroke." Most molecular motors have a head, a neck (which powers movement), and a tail. Myosins usual...em. Soldati and Foth have confirmed that the motor neck and tail evolved together. That finding helped them define some of their new categories. Organisms...

Illegal trade is propelling rare turtle toward extinction, new report

...looking creature prized by collectors, with a long neck that extends far from its body and resembles a snake. The turtle is found only in the wetlands of the island of Roti was first described as a new species in 1994. The report found that poachers are sidestepping regulations and smuggling the turtl...

One-third of adults with diabetes still don't know they have it

... acanthosis nigricans (dark, thickened skin around neck or armpits) have a history of disease of the blood vessels to the heart, brain, or legs have had IFG or IGT on previous testing. ...

Honey helps problem wounds

...t germs such as MRSA. In this respect medihoney is neck and neck in the race to beat the antibiotic mupirocin, currently the local MRSA antibiotic of choice. This is...

Mitochondrial DNA sequencing tool updated

...its predecessor to sequence variations in head and neck cancer samples. The v2.0 also detected nearly thr...variations in the non-coding D-loop of 14 head and neck tumor samples. Included in this tally were several mutations that possibly are informative of the d...

Fatty spheres loaded with siRNA shrink ovarian cancer tumors in preclinical trial

...rexpressed in colon, breast, thyroid, and head and neck cancers. ...

Gene screen for breast cancer better than pathologist's 'eye'

...obtained relatively easily, such as lung, head and neck cancers, pancreatic and cervical cancers." Pathologists look for telltale shapes of cells to determine if cancer is present, but molecular changes in cells, especially for early cancers, are beyond the reach of even the most powerful microscopes....

Brain-computer link lets paralyzed patients convert thoughts into actions

...re spinal cord injury, has been paralyzed from the neck down since 2001. After having the BrainGate sensor implanted on the surface of his brain at Rhode Island Hospital in June 2004, he learned to control a computer cursor simply by thinking about moving it. During 57 sessions, from July 2004 to April...

Making a face: A new and earlier marker of neural crest development

... the face, skull and nerve centers of the head and neck in vertebrates is determined much earlier in development than previously thought, and is independent of interaction with other forming tissues, according to a recent study published in the journal Nature. The collaborators at Yale and Caltech demon...

Winning by a neck -- Giraffes avoid competing with shorter browsers

The giraffe's elongated neck has long been used in textbooks as an illustration...the first real experimental evidence that the long neck of the giraffe might have evolved as a consequence of competition, which provides support for a prev...

Abnormal overexpression of p53 is a predictive molecular biomarker

... radiation and chemotherapy treatment for head and neck cancers now has been found to predict a good progn...h advanced squamous cell carcinoma of the head and neck cancer (SCCHN) whose pre-treatment tumor samples over-expressed p53 protein were significantly more ...

'Erectile dysfunction' drugs heighten natural anti-cancer activity

...ults, as did tissue samples taken from 14 head and neck cancer and multiple myeloma patients. Sildenafil, marketed under the trade name Viagra, is one of a class of drugs used to treat erectile dysfunction in millions of men, and in recent years, its ability to stimulate the production of NO has been...

Stress hormones may play new role in speeding up cancer growth

...eal carcinoma (NPC), a serious, incurable head and neck cancer that occurs most frequently among people of Chinese descent. They treated Glaser's cell line with norepinephrine and, as predicted, the cells all produced MMP-2, MMP-9 and VEGF. This showed that the receptors for this hormone were present o...

Nonvenomous Asian snakes 'borrow' defensive poison from toxic toads

...the snakes to store toxins from the toads in their neck glands. When under attack, the snakes re-release the poisons from these neck glands. Many invertebrates sequester dietary toxins for use in defense, including milkweed insect...

Human preference for other species could determine whether they survive

... display the warmest colors in the upper body, the neck and head. He likened the effect to that of a man in a tuxedo pinning on a red carnation. Unlike some other types of animals, human preference for particular penguin species does not seem to be driven by a "cuteness" factor. The four books Stokes ...

Computer imaging assists with facial reconstructive surgery

...ngle: the intersection of a line drawn next to the neck and a line drawn from the bottom of the chin through the point where the neck and the jaw connect Mentocervical angle: the intersection of a line drawn from the tip of the nose...

Genes and biomarkers that allow doctors to choose the right therapy for the right patient

...gulating the sensitivity of squamous cell head and neck cancer cells to lapatinib, a cancer drug that was ... evaluated 7,000 genetic targets in human head and neck cancer cells to discover specific genes that might shade an individual’s response to Tykerb. "Our...

Cancer vaccines -- Taking a jab at cancer by stimulating the immune system

...f the immune system into targeting p53 in head and neck squamous cell cancer. A phase I clinical trial of ...h will eventually enroll 24 patients with head and neck cancer, has three experimental arms, each including a DC-based vaccine containing p53-derived T cell...

Male reindeer inflate a large air sac in the neck region to emit their hoarse rutting calls

...le reindeer's air sac, influencing vocal sound and neck contour, may contribute to his sexual prowess and .... In this posture the inflated air sac expands the neck region. Both acoustic and optical display serve to deter rival males and thereby prevent fighting, a...

Fused nasal bones helped tyrannosaurids dismember prey

...head nearly one and a half times as long. T. rex's neck power was similarly staggering. For instance, in a split second, a T. rex could toss its head at a 45 degree angle and throw a 50kg person five metres in the air. And that's with conservative estimates of the creature's muscle force, says Snively. ...

Rare soft-shell turtle, nesting ground found in Cambodia

...howing. It possesses long claws and can extend its neck with lightning speed to bite with jaws powerful enough to crush bone. “It has the fastest strike of any animal I’ve ever seen, including cobras,?Emmett said. The researchers also found a nesting ground for the species and brought back eggs tha...

Reconstructing the biology of extinct species: A new approach

...lls that send signals to the brain, triggering the neck and eye muscles to reflexively keep the visual image stable. The basic hypothesis of the project was that the organ of balance -- which helps stabilize an animal's gaze and coordinate its movements as it travels through the environment -- should...

CT scan reveals ancient long-necked gliding reptile

...at flattened, image of a small reptile with a long neck and swept back wings. Gliding behavior evolved several times in reptiles and is present in the Indonesian reptile Draco. ...

Blood test may help signal tumor's remission, return in throat cancer patients

...surgery or drug therapy. “Cancers of the head and neck are insidious because surgical removal of the tumo...ajor goal of the NCI and this research in head and neck cancer is an excellent example of the type of collaborative study between two NIH institutes that he...