multiplex

Inexpensive, mass-produced genes core of synthetic biology advances at UH

...ngle chip are described in apaper titled “Accurate multiplex gene synthesis from programmable DNAmicrochips,?appearing in the current issue of Nature, the weeklyscientific journal for biological and physical sciences research. “Synthetic genes are like a box ofLego building blocks,?Gao said. “Their organizati...

NHGRI expands effort to revolutionize sequencing technologies

...ecule. The ultimate goal is to create a real-time, multiplex single-molecule DNA sequencing system that produces sequence reads containing hundreds of thousands of nucleotides. "$100,000 Genome" Grants NHGRI's "Near-Term Development for Genome Sequencing" grants will support research aimed at sequencing a hu...

Encoded metallic nanowires reveal bioweapons

...es Inc). have now developed a new basis for such a multiplex device: they are using silver and gold "striped" nanowires as supports for simultaneous immunological tests for various pathogens. Individual patterns of stripes act in the role of "barcodes". These "nanobarcoded" particles are manufactured by Oxonic...

Gene screen for breast cancer better than pathologist's 'eye'

...mal cells. The Hopkins test, called quantitative multiplex methylation-specific PCR or QM-MSP, determines the percentage of methylation present in each of five to ten cancer genes. The percentages are added together for a cumulative score, which is compared to a threshold value. Levels above the threshold ...

Making a face: A new and earlier marker of neural crest development

...unostaining of proteins, in situ hybridization and multiplex RT-PCR of mRNAs -- that formation of neural crest cells in chick embryos is independent of both mesoderm and neural tissues. They also identify, Pax7, as an early marker of neural crest formation and prove that its function is required in the earlies...