multiforme in Biological News

UNC study: Scientists identify chemical compound that may stop deadly brain tumors

... gene mutation contributes to tumor growth. The findings and potential treatment apply to a type of brain tumor called secondary glioblastoma multiforme (GBM). GBMs are part of a larger group of brain tumors called malignant gliomas, which is the type of cancer Senator Edward Kennedy suffers from. ...

Salk researchers develop novel glioblastoma mouse model

... suspected to be the origin of glioblastoma. Within a few months, massive tumors that displayed all the histological characteristics of glioblastoma multiforme preferentially developed in the hippocampus and the subventricular zone. The ability of adult stem cells to divide and generate both new stem ...

Mayo Clinic Cancer Center: Harnessing the measles virus to attack cancer

... and lead researcher on the glioblastoma multiforme project in the measles virus investigation. "We ... seek out this protein, entering the glioblastoma multiforme tumor. Upon entry, the virus begins to spread, ... more potent viral doses." The glioblastoma multiforme study, which opened today, is designed to test ...

'Smart drug' targets deadly brain cancer

... categorizes fast-growing glioblastoma multiforme as a grade IV cancer. Significance of the Mayo ... percent) of patients with recurrent glioblastoma multiforme participating in this study -- which is a high ... to target specific changes in the glioblastoma multiforme tumor cells that previous studies have identified ...

Investigating the measles virus as a tool to kill multiple myeloma

... being tested today in several tumor types, including glioblastoma multiforme (a brain tumor), recurrent ovarian cancer and now multiple myeloma. ... of higher and potentially even more potent viral doses. The glioblastoma multiforme trial, which opened in the fall, is testing the safety of another strain ...

Killing brain tumors from within: A 'Trojan horse' approach

... of epidermal growth factor receptors (EGFR). This proliferation of EGFR is typical of certain types of cancer cells, including glioblastoma multiforme (GBM), the most lethal form of brain cancer. The nucleic acid-EFG molecule acts as a "guided missile," explained Prof. Levitzki, which, when ...

Scientist works to improve treatment for brain tumors

... that he developed for the most deadly type of brain tumor. Waldemar Debinski, M.D., Ph.D., pioneered a method to destroy cells of glioblastoma multiforme (GBM) with less damage to healthy cells. The drug is currently being tested in clinical trials and Debinski is working on its fourth generation in ...

Radiotherapy advance points way to noninvasive brain cancer treatment

... With an equal rate of incidence and mortality-the number of those who get it, and the number of those who die from it-Glioblastoma multiforme (GBM) is a brain cancer death sentence. Of the approximately 12,000 people who are diagnosed with GBM annually in the U.S., half will die within a ...

Preclinical study of a new brain tumor therapy

... the malignant cells. A new preclinical study, published in the open access journal PLoS Medicine, has applied the approach to combat glioblastoma multiforme (GBM). This is the most aggressive form of brain tumour, growing very quickly before symptoms are experienced and killing most patients within a year ...