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Man and mouse share genome structures
...certain major methyl and acetyl tags, and used new microarray technology to identify the underlying genetic sequences associated with the tagged chromatin. Next, they teamed up with Michael Kamal, the co-first author of the paper, Eric Lander, and their Broad Institute colleagues, for the daunting computational...Study Demonstrates Gene Expression Microarrays are Comparable and Reproducible
...nstitutes of Health, shows for the first time that microarray datagenerated in different laboratories can produc...ut in multiple locations and would necessitatethat microarray data produced in different laboratories be combined foranalysis. Even if all procedures and equipmen...Breakthrough Microarray-based Technology for the Study of Cancer
...n the modification of its gene-expressionprofiling microarray technology to improve its utility for DNA analysisapplications. This new platform provides high sensitivity, enabling CGHresearchers to reliably identify the single copy deletions inchromosomes that have been the most difficult to detect.Additionally...Improved Outcomes Releases GeneLinker(TM) Gold and Platinum Version 4.6
...fic Officer of IOS. "The feature set required for microarray analysis is becoming moremature so we have been concentrating more on proteomics data recently.For example Silicon Genetics new GeneSpring?7 includes Support VectorMachines (SVMs). SVMs have been available in GeneLinker Platinum formore than a year a...Scientists decipher genome of fungus that can cause life-threatening infections
...ptococcusresearch community already has designed a microarray and has formed aconsortium to further investigate the function of C. neoformans genes.The sequence data also provides the foundation for a broader genomeproject that aims to define the molecular basis for the C. neoformansspecies cluster, which inclu...Nanogen Issued Patent for Electronic Microarray With Memory
...ivation and array usage directly on the electronic microarray cartridge. "This addition to our growing intellectual property portfolio illustrates our ability to develop differentiated advanced diagnostic products that add value to the company and to research and clinical laboratory customers," said Howard C. ...Scientists reveal molecular secrets of the malaria parasite
... the integration ofdraft genome sequence data with microarray and protein expressiondata," says Carlton. "This project also shows the power ofcollaboration between international institutes with different areas ofexpertise. It was remarkably productive collaboration."...Alcohol's effects on gene expression in the central nervous system
...on to produce intoxication. Scientists can now use microarray technology to study brain function gene by gene. S...alyze more than a handful of these genes, however, microarray technology has changed that." Symposium speakers at the June 2004 Research Society on Alcoholism me...An entropy-based gene selection method for cancer classification using microarray data
...based iterative algorithm for selecting genes from microarray data that are able to classify various cancer sub-types with high accuracy. In addition, the feature set obtained is very compact, that is, the redundancy between genes is reduced to a large extent. This implies that classifiers can be built with a s...PANTHER Protein Classification System Database 5.0
...ology) and knownpathways. Its main use is probably microarray analysis - it incorporateautomated GO surrepresentation analysis with graphical output. Best ofall, its available freely . A paper describing the Database is available freely in the Nucleic acids research Journal . AppliedBiosystems (NYSE:ABI), an...Agilent Technologies releases automated literature search tool for biology researchers
...biological entities, such as genes and proteins. A microarray or an LC/MS-proteomics experiment can typically result in hundreds of genes and proteins of interest. Biologists can use the new plug-in to avoid the daunting task of manually searching for each gene and protein in the scientific literature and paten...Affymetrix and the Karolinska Institutet Announce Translational Medicine Strategic Alliance
...nical research institutes with advanced Affymetrix microarray technology. Karolinska Institutet will have access to a number of new microarray technologies from Affymetrix, including the Mapping 100K. The 100K is the first in a family of produ...Affymetrix and Stratagene Announce Strategic Software Alliance
...rt to bring to market breakthrough gene expression microarray technology. By partnering with other thought leaders in our field, we believe we have the opportunity to position our technology as a standard for expression analysis." ...Asthma gene clusters identified
...ttacks," Dr. Hershey said. Previous studies using microarray technology have been conducted using RNA from adults with asthma, but this approach has not been successfully used in human studies involving children with asthma. In pediatrics, it is difficult to obtain tissue in sufficient quantities for analysis,...Viral protein influences key cell-signaling pathway
...vel of p12 protein. The researchers then used gene microarray technology to identify which cellular genes out of 33,000 become either more or less active due to the p12 protein. The researchers found that p12 altered the activity of a variety of genes linked to chemical pathways that control cell signaling, pr...Products containing specific probes for detecting alternative splice forms protected
...y the United States Patent and Trademark Office on microarray products allowing the specific detection of mRNAs produced by alternative splicing, covering microarrays optimised for the discovery of alternative RNA splicing events. The patent protects the probe configuration of a unique set of five oligonucleoti...Affymetrix Licenses Microfluidics Technology From Caliper Life Sciences
...luidics patent estate with Affymetrix' GeneChip(R) microarray technologies. The license extends to the manufacture and sale of GeneChip brand products in all areas of application, including research, diagnostics and applied genomics applications. In exchange for the license, Affymetrix will pay upfront licensin...GeneNotes - A novel information management software for biologists
Analyzing microarray data - or even a simple biological network - can get you lost - quick. Tons of genes, tons of synonyms for each, tons of known interactions, with even more being unknown, tons of database with tons of information... and your job is to make sense of t...Researchers rein in regulatory RNAs
...these unique transcripts. Employing a custom-made microarray chip designed to detect strand-specific expression of 1947 SAT pairs, the researchers discovered that most of the SATs were widely expressed in mouse brain, heart, and testis, as well as in mouse embryonic stem cells and fibroblasts. While some SATs ...CoPub Mapper: mining MEDLINE based on search term co-publication
High throughput microarray analyses result in many differentially expressed g...random chance. To test grouping of genes from real microarray data, 221 differentially expressed genes from a microarray experiment were analyzed with CoPub Mappe...Different microarray systems more alike than previously thought
... a genetic "fingerprint," suggests these different microarray technologies are more alike than once thought. Pu...y ask me what is the best platform on which to run microarray experiments, but there hasn't been a good answer to that question," said Rafael Irizarry, Ph.D., ass...Study: 'homemade' gene expression technology unreliable
... adopting common commercial, rather than homemade, microarray platforms and common sets of procedures are able t...oint of the three papers is that with contemporary microarray platforms, we have a relatively reliable method with which to assess gene expression, we can do so r...... made in conjunction with the extensive release of microarray experimental data into the public domain by the Na...of these sequences will be of great benefit to the microarray bioinformatics community and to databases such as the NCT's CEBS as we seek to make high-quality tox...Virus-host interactions at sea effect global photosynthesis
... made in conjunction with the extensive release of microarray experimental data into the public domain by the Na...of these sequences will be of great benefit to the microarray bioinformatics community and to databases such as the NCT's CEBS as we seek to make high-quality tox...B-15A collides with Antarctic ice tongue
... made in conjunction with the extensive release of microarray experimental data into the public domain by the Na...of these sequences will be of great benefit to the microarray bioinformatics community and to databases such as the NCT's CEBS as we seek to make high-quality tox...One gene links newborn neurons with those that die in diseases such as Alzheimer's
... 3,500 cells for each bird, the researchers used a microarray created in the lab to find out which of the genes in the cells were turned on. This technique allowed them to identify which genes were active, or expressed, by comparing them with 800 known genes from the zebra finch. They expected to find a few ov......il the condition is quite advanced. Agilent's new microarray techniques in comparative genomic hybridization (C...iversity of Western Australia, using Agilent's CGH microarray to provide a more thorough understanding of the genetic makeup of mesothelioma cells, which may ulti...Stanford gut check shows diversity of intestinal ecosystem
...o complement this current approach with the use of microarray technology. The latter will allow them to analyze samples much more quickly. They have been working with biochemistry professor Patrick Brown, MD, PhD, and graduate student Chana Palmer to develop a gene chip that can perform a microbial census on co...Affymetrix Launches New Globin-Reduction Kits and Protocol Developed with PreAnalytiX
... Affymetrix scientists invented the world's first microarray in 1989 and began selling the first commercial microarray in 1994. Since then, Affymetrix GeneChip(R) technology has become the industry standard in molecular......s.com. PathwayStudio?Central builds pathways from microarray data, identifies biomarkers, and models drug responses. The software comes with ResNet?database of 500,000+ functional relationships and MedScan?tool for automatic extraction of information from scientific literature. ResNet?database of functional r...Characterizing Skin Cancer by Microarrays
...oma into radial and vertical portions, and through microarray techniques found that, in the transition from radial to vertical growth, the melanomas lost the expression of certain molecules, resulting in increased risk of metastasis. However, some metastatic tumors retained a gene expression pattern characteri......idual's genotype. Blue eyes is the phenotype. The microarray data Shaulsky and his collaborators used show that...es or equivalents of genes found in humans. Using microarray data alone, they determined the orders in which genes function in a particular pathway in that organ...Gov't Creates Gene Database of Normal Human Tissues
...nother NCI-funded study recently demonstrated that microarray analysis of identical tissue samples at geographic...ges 3 months to 39 years old. The very large cDNA microarray they constructed has more than 42,000 detectors built into two chips using verified cDNA libraries u...Chemical Engineer Kao Explores Antibiotic Synthesis With DNA Chips
...rt--an apt description of antibiotic synthesis. A microarray consists of single-stranded DNA arranged on a wafer the size of a postage stamp. The genetic sequence of the DNA tethered to the chip is known. Then researchers add a sample with an unknown composition of fluorescently labeled DNA molecules. The base...High-powered gene profiles provide clues to genes involved in common form of lung cancer
...t study, Dana-Farber researchers used two forms of microarray technology to bring such abnormalities into focus.... cells with high-resolution cDNA (oligonucleotide) microarray equipment to find chromosome regions containing unusual numbers of gene copies. The technology, deve...Scientists reveal how disease bacterium survives inside immune system cell
...lum with that of a weak strain of S. aureus. Using microarray technology that allowed them to compare about 14,000 different human genes, the researchers discovered how the response to A. phagocytophilum deviates from that of S. aureus, and thus permits the HGA agent to survive. "This study has given us a glob...Identification of specific genes predicts which patients will respond to Hepatitis C treatment
...tients who respond to therapy to those who do not, microarray technology, based in a Banting and Best Department of Medical Research laboratory at University of Toronto, was used to analyze the pattern of genes in all participants. This technology allows scientists to compare levels of expression for tens of th...TGen awarded $7.1 million to accelerate brain disease research
...illion grant that TGen will share with three other microarray centers that are part of the NIH Neuroscience Micr... able to further their research through the use of microarray technology used for scanning through the entire human genome (3 billion letters) and all of the gene...New mitochondrial DNA gene chip may be early cancer diagnosis tool
...at a relatively simple diagnostic test using a DNA microarray "chip" could enable early detection of some solid tumors, including lung cancer. Mitochondrial DNA (mtDNA) plays a role in respiration and the cell's energy conversion mechanism. Since the late 1990s, researchers at the Johns Hopkins University Scho...New technique may speed DNA analysis
...only three steps and could reduce the cost of each microarray to under $50. "This would completely revolutionize diagnostics," said Stellacci. With the ability to mass produce these devices and thus make DNA analysis routine, "we could know years in advance of cancer, hepatitis, or Alzheimer's." Another benefi...New technique helps identify multiple DNA regulatory sites
...only three steps and could reduce the cost of each microarray to under $50. "This would completely revolutionize diagnostics," said Stellacci. With the ability to mass produce these devices and thus make DNA analysis routine, "we could know years in advance of cancer, hepatitis, or Alzheimer's." Another benefi......ence analysis. It is an important component of the microarray data analysis pipeline offered by Genomatix and en...o a researcher's set of genes (for example, from a microarray analysis) generates the full biological network, allowing for functional analysis of the most releva...U-M scientists discover identifying markers for primitive blood-forming stem cells
...s stem cells differentiate." Kiel and Yilmaz used microarray analysis to measure levels of gene activity in three types of cells ?hematopoietic stem cells, multipotent progenitor cells and fully developed bone marrow cells. They selected genes that were expressed at higher levels in the HSC population, as oppo...Researchers discover key to human embryonic stem-cell potential
...me between the Jaenisch and Young labs. Using a microarray technology invented in the Young lab, Boyer and her colleagues analyzed the entire genome of a human embryonic stem cell and identified the genes regulated by these three transcription factors. The research team discovered that while these transcript...Genomatix Microarray Analysis Pipeline achieves Affymetrix GeneChip compatible?status
...veral products with the Affymetrix Inc. GeneChip® microarray platform and that it has joined Affymetrix GeneChi... is committed to seamlessly integrating its entire microarray analysis pipeline with the Affymetrix technology. The Genomatix line of products which achieved G...Customized gene chip provides rapid detection of genetic changes in children's cancer
...ancer. Rather than covering the entire genome, the microarray focuses on suspect regions of chromosomes for sign...r genes active in neuroblastoma, we can modify the microarray to include such regions," he added. "We have customized this tool for neuroblastoma, but the approa...Researchers discover why melanoma is so malignant
...sses. For the second experiment, the team used microarray technology (chips covered with fragments of DNA that can measure gene levels) and found that Slug was expressed in human melanoma. "Really, this isn't that surprising," says Gupta, "when you consider that melanocytes in the skin are direct descendant...Study reveals genomics of inflammation from severe injury
..., the research team described the development of a microarray technique to analyze the entire genome of white blood cells from healthy volunteers and critically injured patients. Next, the team plans to study gene and protein activity in the white blood cells of a large group of trauma and burn patients over lo...Study Unlocks Insects?Secret for Love in the Dark
..., the research team described the development of a microarray technique to analyze the entire genome of white blood cells from healthy volunteers and critically injured patients. Next, the team plans to study gene and protein activity in the white blood cells of a large group of trauma and burn patients over lo...Gene Expression in the Aging Brain
...gene expression, each done on the same type of DNA microarray and each comparing brain regions in young versus old adult humans. In four different regions of the cortex (the brain region responsible for higher functions such as thinking), they found a similar pattern of age-related change, characterized by chan...Navigating the brain for sense of direction as paradigm for higher cognitive functions
...gene expression, each done on the same type of DNA microarray and each comparing brain regions in young versus old adult humans. In four different regions of the cortex (the brain region responsible for higher functions such as thinking), they found a similar pattern of age-related change, characterized by chan...Carnegie Mellon scientists create PNA molecule with potential to build nanodevices
...gene expression, each done on the same type of DNA microarray and each comparing brain regions in young versus old adult humans. In four different regions of the cortex (the brain region responsible for higher functions such as thinking), they found a similar pattern of age-related change, characterized by chan...Microarray technology for tailoring breast cancer therapy
...n profiles of 159 breast cancer patients using DNA microarray analysis. From these samples they identified the g... The researchers suggest that the technique of DNA microarray analysis could be developed to help breast cancer patients who do not benefit from adjuvant therapy,......drinks a day. The group analyses samples using a microarray analysis, a process they pioneered with human brai...om a DNA sample applied to a microscope slide, the microarray computer produces about 50,000 coloured spots showing which genes are expressed or switched on in th...New U. of Colorado at Boulder flu chip may help combat future epidemics, pandemics
...imately one-hundredth of an inch in diameter. The microarray is then immersed in a wash of influenza gene fragm...nfected fluid bind to specific DNA segments on the microarray like a key in a lock, indicating both a match and that the virus signature is present, she said. Th...Gene expression profile helps predict chemotherapy response in ovarian cancer patients
...w findings further establish an important role for microarray gene profiling as a predictor of clinical outcome ... Their work makes use of a DNA technology known as microarray analysis, in which genes expressed by cancer cells are labeled and applied to a glass slide containi...Carnegie Mellon U. transforms DNA microarrays with standard Internet communications tool
...w inspired a revolutionary method to transform DNA microarray analysis, a common technology used to understand g...blends experiment and computation, strengthens DNA microarray analysis, according to its Carnegie Mellon University inventor, who is publishing his findings in th...Setting the standard for computer models of life
...orked very well for other fields - for example the microarray community, by enabling authors, publishers and data providers to work together to improve access to meaningful biological information." ......and in the normal tissue surrounding them. Using microarray technology developed at Ohio State , lead investigators Stefano Volinia and George Calin found 137 different miRNAs expressed in at least half of the cancers, with 43 miRNAs allowing scientists to distinguish the difference between normal and maligna......mors in children. The team used a technique called microarray analysis to study gene expression patterns in samples of human brain tumors called ependymomas. By comparing the gene expression patterns in human ependymomas with those in the normal developing mouse nervous system provided by the BGEM, the St. Jude...Other ContentsphylumphylumphylumphylonphysicalphysicalphysicalphysicalphysicalphysicalphysicalphysicalphysicalphysicalpinealpinealpinealpinnapinnapinocytosispithOther TagsPatternPatternPatternQueenQueenEngineerEngineerEngineerSilverSilverParticleParticleParticleParticleNanotechNanotechNanotechResistanceResistanceResistanceResistanceNerveNerveNerveNerveExtremeExtreme
(Date:10/9/2008)... WASHINGTON, D.C., October 9, 2008 The Indonesia...nnounced a bold commitment to protect the remainin...ndonesian island that holds some of the world,s mo...agreement represents the first-ever island-wide co...y. , The commitment has been endorsed by governo...
(Date:10/9/2008)..., RIVERSIDE, Calif. Essential for life in h... diseases such as rickets and osteoporosis, is now...verall human health, emphasizes UC Riverside,s An...D. , In a paper published in the August issue of...orman identifies vitamin D,s potential for contrib...
(Date:10/9/2008)..., A UC San Diego engineer has revealed a new mod...ipples of slime to crawl upside down beneath the s...echanical and aerospace engineering at the Jacobs ...in the journal Physics of Fluid called "Crawling..." that explains how and why water snails can drag ...
(Date:10/9/2008)... Work by researchers at North Carolina State Univ...lue crabs grown and harvested from freshwater pond...n,t worry, researchers say, because the pond-raise...d brethren. , North Carolina,s native blue crab ...r. Dave Eggleston, director of NC State,s Center f...
Breaking Biology News(10 mins):Saving Sumatra: Indonesia reaches historic agreement 2Vitamin D a key player in overall health of several body organs, says UC Riverside biochemist 2Vitamin D a key player in overall health of several body organs, says UC Riverside biochemist 3Ripple effect: Water snails offer new propulsion possibilities 2Ripple effect: Water snails offer new propulsion possibilities 3Turning freshwater farm ponds into crab farms 2Hope 3A An overlooked tool in the battle against HIV AIDS 25196 1Hope 3A An overlooked tool in the battle against HIV AIDS 25196 2Climate change 3A When it rains it 28really 29 pours 7027 1Climate change 3A When it rains it 28really 29 pours 7027 2SGX Pharmaceuticals Announces Financial Results for the Three and Six Months Ended June 30 2008 7024 1SGX Pharmaceuticals Announces Financial Results for the Three and Six Months Ended June 30 2008 7024 2SGX Pharmaceuticals Announces Financial Results for the Three and Six Months Ended June 30 2008 7024 3SGX Pharmaceuticals Announces Financial Results for the Three and Six Months Ended June 30 2008 7024 4SGX Pharmaceuticals Announces Financial Results for the Three and Six Months Ended June 30 2008 7024 5SGX Pharmaceuticals Announces Financial Results for the Three and Six Months Ended June 30 2008 7024 6SGX Pharmaceuticals Announces Financial Results for the Three and Six Months Ended June 30 2008 7024 7SGX Pharmaceuticals Announces Financial Results for the Three and Six Months Ended June 30 2008 7024 8SGX Pharmaceuticals Announces Financial Results for the Three and Six Months Ended June 30 2008 7024 9Anesiva Announces Second Quarter 2008 Financial Results and Update 7020 1Anesiva Announces Second Quarter 2008 Financial Results and Update 7020 2Anesiva Announces Second Quarter 2008 Financial Results and Update 7020 3Anesiva Announces Second Quarter 2008 Financial Results and Update 7020 4Anesiva Announces Second Quarter 2008 Financial Results and Update 7020 5Anesiva Announces Second Quarter 2008 Financial Results and Update 7020 6Anesiva Announces Second Quarter 2008 Financial Results and Update 7020 7Anesiva Announces Second Quarter 2008 Financial Results and Update 7020 8(Date:10/10/2008)...Michigan received $5 million from the National Ins...esource of high-quality experimental data sets of ...mputer-aided drug design to a new level. , The ...puter programs that can predict the effectiveness ...ciate professor in the U-M College of Pharmacy and...
(Date:10/10/2008)... Johns Hopkins University School,of Medicine is la...ptimizing Adjuvant Breast Cancer Strategies: From ...ent key research data on the latest advances in,br...ents in the treatment of breast cancer have,led to...ons that are,increasingly tailored to the specific...
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Breaking Medicine News(10 mins):Health News:U-M to house leading drug database 2Health News:Latest Research on Breast Cancer Presented in a Virtual E-Conference CME Course 2Health News:Mobile Massage Team Announces Expansion of On-Site Seated Massage Services Throughout Eastern Pennsylvania and the Greater Philadelphia Region 2Health News:Nationally Recognized Faculty Presents Latest Advances in Care of Patients with Breast Cancer 2[0] U-M to house leading drug database[0] Latest Research on Breast Cancer Presented in a Virtual E-Conference CME Course[0] Mobile Massage Team Announces Expansion of On-Site Seated Massage Services Throughout Eastern Pennsylvania and the Greater Philadelphia Region[0] Nationally Recognized Faculty Presents Latest Advances in Care of Patients with Breast Cancer
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