Medications in Biological News

Common chemotherapy drug triggers fatal allergic reactions

... coming back. Both of these patients had received medications before the chemotherapy to reduce the risk of ... recommending the use of corticosteroids and other medications before chemotherapy administration to reduce the ... Cremophor-based paclitaxel should be given medications to prevent hypersensitivity reactions, but what ...

New approach discovered to lowering triglycerides

... and "bad" LDL cholesterol. Widely prescribed medications are often taken to influence all of these issues, ... have not been effective. However, some of these medications have unwanted side effects that remain a concern. ... by fibrate drugs, a group of prescription medications often used for that purpose. Lipoic acid ...

Common gene variants influence risk factor for sudden cardiac death

... death and arrhythmia by limiting the use of medications that affect QT interval in people with these ... "In addition, QT prolongation results from medications leading to drug-induced cardiac arrhythmias and ... This is a cardiotoxic side effect of scores of medications in widespread use and has been a major barrier to ...

Plastic and reconstructive surgery -- in brief

... Patients Common antidepressants and herbal medications may have potentially harmful intraoperative ... recommendations for the management of these medications before elective surgery. The authors suggest that ... million of the $2.4 billion spent of prescription medications was on antidepressants. In 2000, it was ...

Pregnant women with asthma can be more confident about some medicines

... . More trials on medications in pregnancy are necessary Pregnant women ... want to know whether it is possible for the medications they take to harm their baby - and they want to ... Women with asthma can usually keep using the same medications during pregnancy that helped them before. ...

Overuse of narcotics and barbiturates may make migraine worse

... has determined that certain commonly-prescribed medications may have the unintended consequence of increasing ... sufferers nationwide, found that the use of medications containing barbiturates or narcotics which ... short-term may make migraine worse if these medications are overused. Treatment with these classes of ...

New test promises quicker, more accurate evaluation for cystic fibrosis patients

... care and help clear a backlog of promising medications now hung up in clinical trials. The researchers ... effective anti-microbial and anti-inflammatory medications to slow and/or prevent lung damage in young ... expensive to conduct phase 2 or phase 3 trials of medications long enough to detect the changes in FEV1. ...

Risks and benefits of antipsychotics in children and adolescents

... paediatric mental disorders, but the use of these medications in children and adolescents merits careful ... Cardiovascular safety Antipsychotic medications are among the most relevant identified risk ... account the impact of the disease and that of the medications prescribed for the disease, on individual ...

Trends in prescription medication sharing among reproductive-aged women

... 25, 2008Borrowing and sharing of prescription medications is a serious medical and public health concern. ... (Oak Ridge, Tennessee), report that allergy medications (43.8%) and pain medications (42.6%) were the types of drugs most commonly ...

Portable device quickly detects early Alzheimer's

... ATLANTA (January 16, 2008) The latest medications can delay the onset of Alzheimer's disease, but ... somewhat dangerous, like forgetting to take their medications or getting lost, before bringing them in for ... serious symptoms occur and start patients on medications that could delay those symptoms. The Georgia ...

New treatment mechanisms for schizophrenia

... research that, in turn, leads to tests of new medications in our clinics. The January 1st issue of ... target may lead to more specific and better medications for disorders such as schizophrenia. John H. ... comments, It is very clear that very few tested medications actually become new treatments. However, the ...

American Chemical Society's weekly PressPac -- Jan. 2, 2008

... unpredictable group of side effects from modern medications called idiosyncratic drug reactions (IDRs) likely ... no obvious connection to the known effects of a medications ingredients or dosage. Although relatively rare, ... a finding that could lead to the design of new medications for the common digestive disorder, according to ...

How schizophrenia develops: Major clues discovered

... also showed, in mice, that antipsychotic medications like clozapine appear to correct this epigenetic ... This raises the possibility of developing new medications aimed at correcting defects in the mechanisms ... targets for development of new schizophrenia medications is a key effort, because it can lead to more ...

Fever causing headaches for Aussie parents

... of alternating over-the-counter antipyretic medications such as paracetamol and ibuprofen (in products ... that it was very common for parents to give these medications for mild fever and at too frequent doses," Ms ... episode," she said. "Many parents see these medications as having magical qualities such as calming upset ...

UA pharmacy research shows prescribers miss potentially dangerous drug pairs

... because of the high number of drugs Americans take: an average of 2.3 medications is prescribed during each physician office visit. A synopsis of the ... Consequently, patients should be sure to tell their pharmacist of all the medications they are taking. ...

Two dietary oils, two sets of benefits for older women with diabetes

... lifestyle to manage their health. But most will probably be on oral medications for the rest of their lives for managing their diabetes and metabolism, which is fine as long as the medications work. We think there's a chance that nutrition can complement medication ...

ICSI or IVF: Babies born from frozen embryos do just as well

... From our study, the combination of exposure to cryopreservation and medications or both did not significantly impair offspring outcome." The ... none of the specific abnormalities linked to male factor infertility, medications or other environmental triggers such as extended in vitro culture, which ...

American Chemical Society's weekly PressPac -- May 27, 2009

... urgently need new anti-thrombotic agents because traditionally prescribed medications too-often cause dangerous bleeding. At the same time, aging of the ... to a problem that limits the human body's ability to absorb and use medications for heart disease, Type-2 diabetes, cancer and other conditions. It is a ...

Is cherry juice a new 'sports drink?'

... researchers say the early finding indicate cherries may work like common medications used by runners to alleviate post-exercise inflammation. "For most ... the millions of active Americans currently taking over-the-counter pain medications to reduce muscle pain and beyond. A growing body of research suggests ...

Treatment for extreme nausea, vomiting during pregnancy

... de Montral's Faculty of Pharmacy and director of the Research Unit on medications and Pregnancy of the Sainte-Justine University Hospital Center. "The ... than droperidol. Importantly, they found no evidence that either of these medications increased the birth defect rate compared to women who received no ...

CFI awards $854,098 to University of Montreal and partners

... system," says Dr. Leclair. "Using a nanosuspension-based formulation, medications can be swallowed, inhaled, injected or applied topically. This CFI funding ... develop new platform technologies to improve the formulation of existing medications and accelerate the development of new chemically complex drugs." ...

Targeted drug therapy prevents exercise-induced arrhythmias

... deaths in young athletes. Current treatment has been limited to two medications beta blockers, often used at very high doses, and calcium channel ... eliminating the calsequestrin gene) and proposed using the model to study medications and interventions for the disorder. They tried flecainide, a clinically ...

Twin nanoparticle shown effective at targeting, killing breast cancer cells

... many horrors, including those that arise when fighting the cancer itself. medications given during chemotherapy can have wicked side effects, including vomiting, dizziness, anemia and hair loss. These side effects occur because medications released into the body target healthy cells as well as tumor cells. The ...

Using hair to manage HIV/AIDS and predict treatment success

... risk uninfected women established in 1994. "Women taking antiretroviral medications may have more adverse events than men taking these regimens. The safety trials of these medications were conducted in trials consisting largely of men, and the highest ...

Anakinra for rheumatoid arthritis: A modest benefit with some risk

... with the only modest beneficial outcomes compared to other biologic medications studied for rheumatoid arthritis," said lead researcher Dr. Marty Mertens ... basis of these results, we recommend that doctors avoid combining biologic medications with anakinra when treating patients with rheumatoid arthritis,' said ...

Researchers engineer pancreatic cell transplants to evade immune response

... transplant recipients are forced to take powerful immunosuppressant medications that have toxic side effects and raise the risk of infection. This advance ... can control type 1 diabetes, recipients must take immunosuppressant medications in order to prevent rejection of these beta foreign cells. "Ultimately, ...

UC Davis discovery offers hope for treating kidney cancer

... in their ability to rapidly create copies of themselves. While the latest medications slow down that process, they do not tend to be curative and have many side ... as effective as possible at the lowest doses possible." Newer medications work by destabilizing cancer cells at the DNA level, which reduces their ...

Pitt research identifies new target in brain for treating schizophrenia

... Brain activity was then normalized both by established antipsychotic medications that regulate only dopamine and by experimental treatments that ... experimental drugs that work on the glutamate system. They found that both medications normalized brain activity. ...

Genes that control cell death fingered in age-related hearing loss

... other factors that play a role in presbycusis include sound exposure, medications that can damage hearing, the condition of the brain as it deteriorates ... when working with power tools or hunting, for example. Since many medications can damage hearing, patients should speak at length with their doctors ...

American Chemical Society's Weekly PressPac -- Sept. 10, 2008

... ARTICLE #5 EMBARGOED FOR 9 A.M., EASTERN TIME, Sept. 15, 2008 New medications for schizophrenia Chemical & Engineering News New scientific ... In the article, C&EN Assistant Editor Carmen Drahl notes that existing medications for schizophrenia, so-called antipsychotics, help ease some symptoms, such ...

New genes found for inflammatory bowel disease in children

... who will better respond to anti-TNF drugs," said Hakonarson. Anti-TNF medications such as those mentioned above are currently given intravenously or as ... pharmaceutical companies to develop anti-TNF drugs in pill form, the medications will be easier to deliver as well as more customized to each patient." ...

American Chemical Society's Weekly PressPac -- Aug. 13, 2008

... says study leader David G. Bailey. "The concern is loss of benefit of medications essential for the treatment of serious medical conditions." Bailey and ... in the blood. Since then, other researchers have identified nearly 50 medications that carry the risk of grapefruit-induced drug-overdose interactions. As a ...

Weill Cornell science briefs June/July 2008

... HBV who have never been treated before by one of the current standard medications for HBV. The drug blocks an enzyme called DNA polymerase in order to stop ... of the disease. Patients who have previously failed to benefit from medications for Crohn's disease are enrolled in the trial to test the safety and ...

Medicines derived from cannabis: a review of adverse events

... are available for medical purposes in Canada. As the use of cannabinoid medications increases, so do concerns about their potential to cause "adverse events," ... the adverse events reported in 31 separate clinical studies of cannabinoid medications conducted between 1966 and 2007. Adverse events were categorized as either ...

At Boston symposium, NARSAD researchers report on genes and family traits

... treatment, whether medication or talk therapy. In addition, antidepressant medications often come with troubling side effects, such as sleep changes, sexual ... Perlis believes that studying how variations in genes affect response to medications will also lead to a completely new class of more targeted antidepressant ...

Many African-Americans have a gene that prolongs life after heart failure

... evidence that genetic differences contribute to the way people respond to medications and should encourage the use of genetic testing in clinical trials to ... many genetic variants that someday can ensure that patients receive the medications that are most appropriate for them. Right now, we know one variant that ...

People with diabetes may have all natural citrus supplement

... could mean less disability and expense from complications and associated medications and certainly less stress for the patient. Although there were no ... a pilot study, twenty adults with diabetes who were taking oral diabetes medications were randomly assigned to receive either Diabetinol or a placebo twice per ...

Genetic variant predicts antipsychotic response for schizophrenia patients by ethnicity

... genetic component contributing to increased risk. Available antipsychotic medications treat some of the symptoms of schizophrenia, but are typically effective ... that in this era of medicine, the selection of particular antipsychotic medications for particular patients with schizophrenia is more art than science. We ...

Drug dosages often incorrect for obese patients

... issue. The problem is somewhat less of a concern with dosages of medications that patients take for extended periods, such as blood pressure or cholesterol medications, because the results of taking those medications are more routinely monitored and dosages can be increased as necessary. ...

American Chemical Society's Weekly PressPac -- Sept. 26, 2007

... for lupus also known as SLE include high doses of steroids and other medications with serious side effects. The new approach targets abnormal immune ... C&EN assistant editor Carmen Drahl describes potential new migraine medications that may be safer and more effective than existing drugs. A class of ...