Median in Biological News

Organic soils continue to acidify despite reduction in acidic deposition

... The study showed that over the 17-yr interval, median base saturation in the Oa-horizon decreased from ... (CaN) and exchangeable aluminum (AlN). The median CaN declined by more than 50%, from 23.5 to 10.6 cmolc/kgC, while median AlN more than doubled, from 8.8 to 21.3 ....

Experimental chemotherapy regimen shows promise in treating advanced lung cancer

... cancer, the response rate was 22 percent with a median survival time of 10.2 months. In this study, ... enrolled at 14 centers in Japan and received a median of five cycles of treatment. The response rate for the combination therapy was 28 percent, median progression-free survival was 4.9 months ...

Prostate cancer vaccines more effective with hormone therapy

... survival probability was 71 percent and the median overall survival was 4.4 years. Patients ... survival probability was 100 percent with a median overall survival of 6.2 years. For patients who ... survival probability was 75 percent with a median overall survival of 3.7 years. Arlen said the ...

Eribulin mesylate demonstrated anti-tumor activity in patients with advanced breast cancer

... York. The subjects in this trial had received a median of four prior chemotherapy regimens that included ... 291 were treated with eribulin mesylate. The median age of those patients was 56 years (range: 26-80 ... 1 and 8 of a 21-day cycle. Patients received a median of four cycles of eribulin mesylate (range 1-27). ...

Pregnant patients lose out in breast cancer treatment; a new approach is needed

... breast cancer five years after diagnosis. The median gestational age at the time of diagnosis was 21 weeks, and the median age of the women 33 years. Some patients chose ... alone, and 2.7% had no treatment at all. The median time for delivery was 36 weeks, slightly earlier ...

Promising new treatment option for women with recurrent ovarian cancer

... pegylated liposomal doxorubicin 50 mg/m2 alone every 4 weeks. The median length of progression-free survival for women on the combination therapy ... who had relapsed more than six months after the first-line therapy, the median progression-free survival time was 9.2 months for the combination ...

Study shows cancer vaccines led to long-term survival for patients with metastatic melanoma

... progenitor cells that can create new depots of cancer throughout the body. Data showed that the projected five-year survival rate is 54% at a median follow up of 4.5 years (range 2.4 to 7.4) for the 30 surviving patients. Although not a direct comparison, the results are superior to those observed ...

Data published in the New England Journal of Medicine support use of raxibacumab (ABthrax) for the treatment of inhalation anthrax

... benefit to animals showing clinical signs of disease caused by exposure to a dose of aerosolized anthrax spores that was approximately 200 times the median lethal dose. We also note that the safety profile shown in healthy human volunteers provides support for use of raxibacumab in the clinical setting ...

Pitt team first to profile genes in acutely ill idiopathic pulmonary fibrosis patients

... the lung-scarring disease progresses gradually and lung function slowly deteriorates. But there is neither a cure nor effective treatment, so median survival is about three years. For unknown reasons, some IPF patients experience rapid declines that cause diffuse damage of the lung alveoli, the ...

NIST issues human milk and blood serum SRMs for contaminant measurements

... containing 172 selected contaminants. The fortified samples contain a concentration of those contaminants at levels five to 10 times higher than the median concentrations found in the U.S. population. NIST SRMs have been rigorously tested and certified as having specific properties that researchers ...

Green tea may affect prostate cancer progression

... of normally brewed concentrated green tea, according to Cardelli. The time of study for 25 of the 26 patients ranged from 12 days to 73 days, with a median time of 34.5 days. Findings showed a significant reduction in serum levels of HGF, VEGF and PSA after treatment, with some patients demonstrating ...

Women more vulnerable to tobacco carcinogens, new results show

... studied 640 patients whose non-small-cell lung cancer was surgically removed over a 10-year period, 239 of whom were women. They found that median survival after surgery was 2.1 years for men, and 4.7 years for women. ...

Many middle-aged and older Americans not getting adequate nutrition

... of calcium, magnesium, potassium and vitamin C was similar between supplement users and non-users for both men and women, there were differences in median dietary intake levels between the different ethnic groups. Chinese Americans tended to have the lowest dietary intakes, particularly in calcium where ...

Nutritional supplementation program helps prevent weight loss among children in African country

... supplementation, according to a study in the January 21 issue of JAMA . Wasting (defined as a certain deviation that a child's weight is from the median [midpoint] weight of a child of the same height in a reference group) is characterized by the loss of weight and muscle mass. It affects ...

December 2008 Geology and GSA Today media highlights

... sulfate. The later generations of sulfide have 34S values in successively smaller ranges, coincident with the mode that is around the median value of the whole data set. Together with textural evidence, sulfide trace element data, and gold occurrence, the data demonstrate that metamorphism ...

Yale researchers unravel mystery of brain aneurysms

... at risk of developing this deadly problem. These genetic findings provide a starting point for changing that equation," Gunel said. The median age when hemorrhagic stroke occurs is 50 years old, and usually there are no warning signs. In the majority of cases, the resulting strokes cause ...

Hypertension disparity linked to environment

... minimal difference in social environments. The EHDIC study examines racial disparities among African Americans and non-Hispanic whites with the same median socioeconomic status who reside in the same community. NHANES, a cross-sectional survey, reviews the health, function and nutritional status of ...

Study reveals homeowner perceptions in fire-prone areas

... the Forest Service had some level of responsibility for reducing fire risks and on average assigned it the most responsibility. The agency received a median grade of B for its fire-reduction efforts during the last year, along with the California Department of Forestry and individual homeowners. ...

Nitrate concentrations of ground water increasing in many areas of the United States

... and resampled once during 2000?. Findings show statistically significant increases in concentrations of nitrate in 7 of the 24 well networks. median nitrate concentrations of three of those seven well networks increased above the USEPA maximum contaminant level of 10 parts per million. ...

Is yakult helpful in the treatment of irritable bowel syndrome?

... After 6 week of treatment with 1 x 65 mL dose of Yakult(R) daily, 9 of 14 patients (64%) completing the study had reversal of ERBHAL, with the median time of first rise increasing from 45 to 75 min (P = 0.03). Furthermore, symptoms improved in those in whom ERBHAL was corrected. The results ...

Treatment delays result in poor outcomes for men with breast cancer

... underwent surgery to remove their cancer. After surgery, 48 received radiotherapy and 100 received adjuvant chemotherapy or hormone therapy. After a median follow-up of 5.2 years, the estimated 10-year disease-free survival rates were 80% for men with the earliest stages of disease, and 44% for those ...

New type of drug shrinks primary breast cancer tumors significantly in just 6 weeks

... We saw significant tumour regression after six weeks of single agent lapatinib, said Dr. Rodriguez. Bi-dimensional tumour measurements showed a median decrease of minus 60.8%. We had previously showed that tumour-causing breast cancer stem cells were resistant to conventional preoperative ...

Biomarkers allow doctors to match therapy to patient

... were low-expressors of HER2 demonstrated an increased number of E75-specific CD8+ T cells when compared with the vaccinated over-expressors. At a median follow-up of 30 months, disease recurrence rates were similar between HER2 over-expressors in both the vaccine and control groups, with recurrence ...

Studies: Children obese due to a host of unhealthy pressures

... have contracts with a soft drink bottling company, which in many cases gives students access to soft drinks all day long. Estimates of the median annual revenue for soft drink contracts in high schools turn out to be $6,000 ($6.48 per student), while for middle schools the annual revenue is ...

Low vitamin D linked to higher risk of hip fracture

... women enrolled in the Womens Health Initiative Observational Study Cohort who had experienced hip fracture, confirmed by their medical record, over a median of 7.1 years. Levels of 25 hydroxyvitamin D, an indicator of vitamin D status, in the bloodstream were measured for these patients and compared with ...

Presence of gene mutation helps guide thyroid cancer treatment

... the mutation was associated with older age, lymph node and other metastasis, and was an independent risk factor for recurrent and persistent disease. median follow-up time of all patients in this study was six years. Kebebew explained that identification of the mutation in patients with thyroid cancer ...

UF scientists discover evolutionary origin of fins, limbs

... genes in shark embryos, they determined shark median fin development is associated with the presence ... types to determine which cells give rise to the median fins, finding that they arise from the same cells ... tells us they must have been assembled in the median fins first, and later in evolution this entire ...

Medical experts: US unlikely to have enough vaccines to stop avian flu

... the Pandefense 1.0 meeting in November gave a median estimate of a less than 1 percent chance that the ... the next three years. The same experts gave a median estimate of 15 percent for the probability that ... by human-to-human contact within that time. Their median worst-case estimate of the number of people who ...

Agent slows aging in mice

... on a normal diet. Scientists measured the difference at a point called median lifespan, when half the control mice had died of natural causes associated ... is the first time to my knowledge when an agent has been shown to extend median life span in three laboratories,” says Miller, professor of pathology at ...

Intravenous nanoparticle gene therapy shows activity in stage IV lung cancer

... two or more doses experienced stable disease for three to seven months. median survival time for all patients is 14.6 months, which Lu notes compares favorably to a seven-month median survival time for patients receiving second line therapy. All ...

Combined treatment extends life expectancy for lung cancer patients

... In a retrospective study looking at patients over seven years, the median survival rate at three years increased from 20 months after radiation ... to destroy them. For patients who cannot have surgery or radiation, the median survival is about one year. In this study, researchers looked ...

'Smart drug' targets deadly brain cancer

... Current treatment outcomes for this type of cancer are extremely poor: median patient survival is 12 to 16 months, and recurrent disease has a dismal ... is usually treated with surgery, radiation therapy and chemotherapy -- and median survival is 12 to 16 months. For patients in whom the disease recurs, the ...

Liver cancer patients with high serum levels of hepatitis B virus face poorer outcomes

... and clinical signs and symptoms. They then performed statistical analysis to assess which factors might have influenced patient outcomes. The median survival of all patients was 6.83 months. Patients with high pre-treatment HBV DNA had a significantly higher incidence of developing severe ...

Study calculates patient time costs associated with cancer care

... how long each patient spent traveling to, waiting for, and receiving care. The net costs were calculated using a dollar value of $15.23 per hour, the median U.S. wage rate in 2002. During the first 12 months after diagnosis, the average length of time for hospitalization was highest for patients with ...

Indicators for risk of heart disease are higher in passive smokers

... (NHANES III, 1988?4), which included 7,599 adults who had never smoked. Sixty-eight percent of the participants were women, with participants' median age being 38. Eighteen percent of participants had no detectable levels of cotinine; the rest were classified as having either low or high cotinine. ...

UCSF brain tumor vaccine trial shows promising results

... currently be evaluated for overall survival, while four are still receiving treatment. Seven out of the eight patients have exceeded the historical median benchmark of 6.5 months survival from time of recurrence. The investigators will continue to follow the patients for overall survival. Based on these ...

Finnish scientists discovered a new approach to treat virus-induced lymphomas

... is a human tumor virus and an etiological agent for Kaposi’s sarcoma and primary effusion lymphoma (PEL). PELs are aggressive lymphomas with reported median survival time shorter than six months after diagnosis. Researchers at the University of Helsinki have discovered that activation of the p53 pathway ...

Genes and biomarkers that allow doctors to choose the right therapy for the right patient

... a variety of forms including rashes, eczema and fissures. Skin toxicity also indicates a poor response to cetuximab. The study indicated that median survival is 15.6 months for patients with skin toxicity and without a KRAS mutation; whereas the survival is only 5.6 months for patients with the ...

Monitoring poisons in the environment -- a woolly matter

... March ?2nd April). Significant correlations were found between the amount of copper and lead found in washed wool from sheep and in local streams. median copper concentration in North Ronaldsay wool was comparatively high despite lower soil concentrations. Shetland sheep appeared to accumulate more ...