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W.M. Keck Foundation funds study of friendly microbes

.... To do so, the researchers will use a new type of mass spectrometer with an unprecedented capacity to accurately and rapidly identify these metabolites. "We very grateful to the Keck foundation, which has committed itself to funding high-risk projects designed to overcome key obstacles in emerging field...

Current human embryonic stem cell lines contaminated UCSD/Salk team finds

...esence of Neu5Gc with a processcalled electrospray mass spectrometry. The percentage of total sialicacids present as Neu5Gc in the embryonic stem cells varied from 2.5 to10.5 percent. In human embryonic stem cells that had been allowed todifferentiate into embryoid bodies (EB), which is the first step inp...

Another Look Finds Promising Proteomics Test is Not Biologically Plausible

...Lancet. That study reported dramatic results using mass spectrometry to search for a pattern of proteins i...f Medicine). They say the issue centers on how the mass spectrometer data were analyzed. A mass spectrometer is an instrument that can quantitatively measu...

New species from old data

...Lancet. That study reported dramatic results using mass spectrometry to search for a pattern of proteins i...f Medicine). They say the issue centers on how the mass spectrometer data were analyzed. A mass spectrometer is an instrument that can quantitatively measu...

Cracking the olfactory code in bees

...Lancet. That study reported dramatic results using mass spectrometry to search for a pattern of proteins i...f Medicine). They say the issue centers on how the mass spectrometer data were analyzed. A mass spectrometer is an instrument that can quantitatively measu...

Signaling protein builds bigger, better bones in mice

...Lancet. That study reported dramatic results using mass spectrometry to search for a pattern of proteins i...f Medicine). They say the issue centers on how the mass spectrometer data were analyzed. A mass spectrometer is an instrument that can quantitatively measu...

Ecological destruction fuels emerging diseases

...here have been episodes of major climate change or mass extinction, and species have moved out of their areas of origin into other areas, there have been emerging diseases. Parasites have moved into new areas and they've jumped ship into new hosts." He will present his latest findings on February 21 as p...

Inexpensive, mass-produced genes core of synthetic biology advances at UH

...g edge of this field. Her recent findings onhow to mass produce multiple genes on a single chip are described in apaper titled “Accurate multiplex gene synthesis from programmable DNAmicrochips,?appearing in the current issue of Nature, the weeklyscientific journal for biological and physical sciences res...

Researchers reveal the infectious impact of salmon farms on wild salmon

...ce, the juveniles have had the time to put on body mass and build resistance. The location of the farm near the natal rivers undermines this natural coping strategy. The field study also discovered a new cause for alarm: once the young salmon pass the farm and pick up the sea lice, the migrating school b...

Potential Cure for Lymphoma in HIV patients

...atient had bulky disease (indicated by a cancerous mass greater than 5?10 cm).Reversible abnormalities in liver function, a side effect of theintensive treatment, were experienced in a majority of the patients.One patient, the oldest in the study, developed cardiomyopathy (aweakening of the heart) and kid...

Antibodies from plants protect against anthrax

... place calculated to induce maximum terror through mass casualties. The unpredictable nature of such events compels us to develop cost-effective, highly stable medical countermeasures to enable authorities to treat individuals exposed to bioterror agents such as anthrax," says Les Baillie of the Naval Med...

UF Researchers Map Bacterial Proteins That Cause Tooth Loss

...tification Technology, or MudPIT. Once separated, mass spectrometry was used to measure each protein’s mass and charge, identifiers as unique to proteins as the whorls of fingerprints are to people. The spec...

Vascular structure and function improve with diet and exercise

...efficiency of the heart to relax. Left ventricular mass is a measure of end organ damage often following the onset of LVDF abnormalities. The brachial (arm) and carotid (neck) arteries were tested for intima-media thickness and arterial distensibility. Both reflect the health of the blood vessels. The th...

Bone Density Recovers After Teens Stop Injected Contraceptive

... women are developing a large amount of their bone mass from ages 15 to 19, researchers were concerned tha...t bone density while using DMPA and increased bone mass after discontinuing the contraceptive. However, the younger women in the current study both lost bon...

Researchers develop rapid diagnostic tool for pathogen identification

...bes for pathogens were coupled to markers known as mass codes. After amplification, incorporated mass codes were detected by mass spectroscopy allowing identification of the pathogen. According to Thom...

US life expectancy about to decline, researchers say

... everyone who is currently obese acquired the body mass index of people who have the lowest risk of death. By calculating years-of-life-lost due to obesity and combining that with estimates of the prevalence of obesity in younger generations, the authors were able to illustrate that in the coming decades...

How the environment could be damaging men's reproductive health

...s weight; babies born to underweight fathers (body mass index less than 20kg/m2) were six times more likely to have undescended testes. However, Dr Jorgensen said: "This finding should be treated with caution because the number of cases was rather low and only larger studies will be able to show whether ...

UCLA launches $20 million stem cell institute to investigate HIV, cancer and neurological disorders

...ene expression analysis, proteomics using advanced mass spectroscopy, large-scale computational facilities for bioinformatics, and world-class multi modality imaging facilities for analysis of stem cell therapies in laboratory models and, ultimately, in patients enrolled in clinical trials. "UCLA encoura...

Chemists identify immune system mechanism for methamphetamine binges

...iction. In theory, antibodies to the drug could be mass produced and administered at therapeutic levels that are high enough to clear the drug from the body, he says. "Methamphetamine has become the ‘crack' of the 21st century," Janda says. "We're just starting to unravel its mechanism of addiction." Fur...

Great White shark evolution debate involves WSU Lake Campus geology professor

...cale changes of life over time and how things like mass extinction affect the course of life," he said. Ciampaglio discussed his shark research findings at recent Geological Society of America meetings in Mississippi and Colorado. A scholarly journal article on the subject is pending. The geologist join...

A frog's life is food for thought

...ssive meals equivalent to 50 percent of their body mass and maximise their digestive capability from the o...leled with the small intestine having increased in mass by 450 percent within just 36 hours." The results of Ms Cramp's study could have important implicat...

Biodiversity hotspots identify conservation priorities

...ost famous wildlife spectacles, the over wintering mass of monarch butterflies (Danaus plexippus) in the pine forests of Michoacan. Threats to the hotspot include logging and intentional burning to clear land for livestock or agriculture. Hotspots Revisited was produced by CEMEX, one of the world's large...

Low level of extinction during ice age linked to adaptability

...ture and sea levels. Those that were not died in a mass extinction that heralded the ice age's onset. "These results not only clue us in to what happened many millions of years ago, but they also have implications for understanding the modern marine ecosystem," said Matthew Powell, a doctoral candidate i...

Increased risk of osteoporosis associated with gene that one in five people have

...ty in both the spine and the upper femur. The bone mass of the spine proved not to be affected by genetic ...te peak bone density and would lose even more bone mass after menopause. If we can catch them at an early age, we can maximize their chances to avoid osteop...

Microbial forensics: The next great forensic challenge

...fense Analysis. Murch created the FBI's weapons of mass destruction forensic unit in 1996 and has been a leader in this area of our national response since then. "An effective program requires relevant, exploitative, fully validated methods and uses in all aspects of the forensic investigative process," ...

Super predators and mass extinctions

...d to cycles that correspond to our 26 million year mass extinctions. Previous models that do not show these sorts of cycles could be faulty, according to Lipowski, because they failed to account for the effects of limited living spaces shared by a large number of different species. A. Lipowski Phys. Rev...

NASA study finds snow melt causes large ocean plant blooms

... and evaporation of wet soil. As a result the land mass heats up more in summer creating a larger temperature difference between the water of the Arabian Sea and the Indian subcontinent landmass. The temperature difference is responsible for a disparity in pressure over land and sea, creating a low press...

Integration of Agilent's MS technology, Proteome Systems' software to help scientists in proteomics research

...lycomIQ software, a comprehensive platform for the mass spectrometric analysis of protein-associated glyca...h the Agilent XCT, XCT Plus and XCT Ultra ion trap mass spectrometers. Proteome Systems developed GlycomIQ to address the emerging field of glycomics, whic...

Scientists discover that three overlapping signals in embryo help get the backbone right

... Spemann and his student Mangold found that as the mass of cells in the embryo started to take form, a region in the embryo - what they called the "organizer" - seemed to be the source of signals to nearby cells, telling them to form back structures. What clinched their experiment was taking the organizer...

Oceans more vulnerable to agricultural runoff than previously thought, study finds

...on, caused by excessive algae growth. As the algal mass sinks, it is consumed by bacteria, which use up most of the oxygen in the water as they multiply. The result is an oxygen-depleted dead zone at the bottom of the sea where few creatures can survive. A massive dead zone appears every summer in the Gul...

Elephant seal pups suffer from ocean warming

...arching for food. As a result, they gain less body mass while pregnant and have fewer reserves to draw on ...raging time of about 36% (as well as a decrease in mass gained). After 1999, however, the declining trend abruptly stopped and the weaning weight of the pup...

Product improves peptide identification for proteomics research

...E: A) today introduced a high-performance ion trap mass spectrometer (MS) that allows pharmaceutical and a... improved scan cycle times, enabling collection of mass spectra at rates up to three times faster than its predecessors. "The combination of the new LC/MSD...

Low oxygen likely made Great Dying worse, greatly delayed recovery

The biggest mass extinction in Earth history some 251 million years... extinction rate and slowed recovery following the mass extinction, Huey said. "Biologists have previously thought about the physiological consequences of ...

Scientists reveal the shape of a protein that helps retroviruses break into cells

The biggest mass extinction in Earth history some 251 million years... extinction rate and slowed recovery following the mass extinction, Huey said. "Biologists have previously thought about the physiological consequences of ...

Scientists generate patient-specific stem cells, Science study says

.... Stem cells were then derived from the inner cell mass of the blastocyst. In laboratory culture, these cell lines displayed signs of immunological compatibility with the patients' cells, Science authors reported. Oocyte donors and patients who donated non-reproductive cells were all unpaid volunteers. A...

SuperLigands - a database of ligand structures derived from the Protein Data Bank

.... Stem cells were then derived from the inner cell mass of the blastocyst. In laboratory culture, these cell lines displayed signs of immunological compatibility with the patients' cells, Science authors reported. Oocyte donors and patients who donated non-reproductive cells were all unpaid volunteers. A...

Python a 'hearty' eater

...n experiments, the python's ventricle increased in mass by 40 percent within 48 hours. Unlike a human hea...ng humans, a 10-30 percent increase in ventricular mass can occur following several weeks to months of intense aerobic training," said Hicks. In the snake,...

Research shows smoking adds a decade to reproductive age of IVF patients

...F and more than 7% were overweight i.e. had a body mass of 27kg/m2 or more. Older women had lower success rates no matter what was the cause of subfertility, with the live birth rate decreasing by 2% for each additional year of age. "In all subgroups smokers had a lower delivery rate per treatment cycle...

Unlike other mammals, newborn dolphins and orcas stay active 24/7 during first months of development

...om predators, help maintain body temperature until mass and blubber insulation develop, allow frequent respiration at the surface, and facilitate rapid growth of brain and body and related behavioral development. "Somehow these seafaring mammals have found a way to cope with sleep deprivation, facilitati...

NASA probe could reveal comet life, scientists claim

...ble pile, nor a conglomerate of ices, but a porous mass of organics and ice under the black asphalt crust." Comets are thought to have accumulated from a mixture of ices and organic interstellar dust at the time the solar system was formed some 4.6 billion years ago. "This material is quite porous, so i...

Mice brains shrink during winter, impairing some learning and memory

... kept in short days had on average a smaller brain mass compared to the other mice, even when taking into account that their overall body mass was smaller, too. In addition, the researchers found changes in a region of the brain ?the hippocam...

Research may provide new link between soft drinks and weight gain

...that favors fat storage. "Our study shows how fat mass increases as a direct consequence of soft drink consumption," said Dr. Tschöp. The research appears in the July 2005 issue of Obesity Research, the official journal of the North American Association for the Study of Obesity (NAASO). Consumption of ...

Roundup®highly lethal to amphibians, finds University of Pittsburgh researcher

...iodiversity and an 86 percent decline in the total mass of tadpoles. Leopard frog tadpoles and gray tree frog tadpoles were completely eliminated and wood frog tadpoles and toad tadpoles were nearly eliminated. One species of frog, spring peepers, was unaffected. "The most shocking insight coming out of ...

New miniaturised chip dramatically reduces time taken for DNA analysis

...es and testing genetic toxicity in new drugs. Once mass production of the sensors begins, their cost and availability will be similar to that of pregnancy test kits found in pharmacies. The researchers Salvador Alegret, Manuel del Valle and Maria Isabel Pividori, all of whom are members of the Sensors an...

Hopkins AIDS experts issue warning about global efforts to provide drug therapies

... discovery of insulin for diabetes in 1922 and the mass distribution of the antibiotic penicillin in 1943. In the case of diabetes, insulin's availability turned a once-fatal disease into a chronic, manageable, lifelong one, like antiretroviral therapy has done for HIV. However, the researchers point out...

Researchers reveal secrets of flying snakes

...light with 16 size and behavior variables, such as mass and snout-vent length, of the animal's body. He found that body length and wave amplitude are important predictors of flight behavior, but wave frequency was not. "These high-amplitude undulations visually dominate the behavior, yet their frequency ...

Team Invents Device For Weighing Individual Molecules

...d, the molecules condense on the bar and add their mass to it, thereby lowering its frequency. In other wo... then able to evaluate extremely subtle changes in mass of the nanodevice, and therefore, the weight of the added atoms or molecules. Roukes says that thei...

Proteomics brings researchers closer to understanding microbes that produce acid mine drainage

...se short proteins, called peptides, with "shotgun" mass spectrometry. To identify the peptides from their masses, they turned back to the genomes. The genomes they obtained last year allowed them to predict the proteins in each member of the biofilm community, and from that predict the protein fragments t...

UCR chemist part of team identifying new areas of gene regulation

...regulation is thought to take place. The team used mass spectrometry to show that acetylation at the core ... location of acetylation. "In this paper, we used mass spectrometry to identify a novel acetylation site at the lysine 56 of yeast histone H3," said Zhang,...

It's electric: Cows show promise as powerplants

...d until it can be completely digested. This liquid mass is what scientists call rumen fluid. The researchers collected the fluid through a cannula, a surgically implanted tube that leads directly from the cow's hide into its rumen. The cow used in the study ate a normal diet. The researchers filled each...

Researchers discover mechanism for multiplying adult stem cells

...s process is reversible, after you have a critical mass of these cells, you can then place them back into the person where they would grow into healthy tissue." "This could be very beneficial for burn victims," Jaenisch adds. Researchers in his lab are also exploring whether activating Oct4 in somatic c...

ORNL, UC Berkeley unravel real-world clues to Earth's mysteries

... several years. Meanwhile, ORNL boasts world-class mass spectrometry instrumentation and its researchers h...n ORNL's Chemical Sciences Division, performed the mass spectrometry work. Manesh Shah of ORNL's Life Sciences Division was responsible for the informatics ...

New Vaccine To Be Used For First Time In Polio Outbreak Response

... second half of May. Yemen had already conducted a mass campaign on 11-14 April, as the country was considered to be at high-risk of polio re-infection from nearby Sudan where an outbreak of polio continues. Experience in polio eradication demonstrates that outbreaks can be quickly contained with high qu...

Male Combat Veterans Rank High In Heart Disease Risk

...rs used the standard definition of obesity, a body mass index of 30 or higher, she said. "Consistent with younger veterans of more recent wars, older men with distant combat exposure had higher odds of heavy smoking, heavy drinking and obesity, but lower odds of physical inactivity compared to non-vetera...

Researchers develop new method for facile identification of proteins in bacterial cells

...tracts of microorganisms using traditional peptide mass fingerprinting (PMF). The key to the new method, a...ssisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS), which identifies protein fragments based on the time they need to trave...

Scientists turn tobacco against cancer

... scientists are seeking industry partners to begin mass production of the antibody. The next step in the work, Dr. Koprowski notes, would be to conduct a phase 1 clinical trial of the monoclonal antibody in colorectal cancer patients. In the meantime, they are studying the effectiveness of monoclonal anti...

Multi-species genome comparison sheds new light on evolutionary processes, cancer mutations

...ly similar genomes. Researchers speculate that the mass extinction opened new ecological niches for mammals, spurring their diversification and the emergence of new mammalian orders. This situation would have facilitated opportunities for the isolation of mammals into more distinct breeding groups, speedi...

Female volunteers prepare for a second 'bedrest'

...gned to counter the loss of muscle, fluid and bone mass and the reduction of certain functions (such as cardiac function and movement). While the control group did not perform any particular activity, an 'exercise' group were put through their paces in regular exercise sessions. In another group, daily m...

Oxygen increase caused mammals to triumph, researchers say

...ments, thanks to two high-precision, isotope ratio mass spectrometers housed in the geological sciences department at Rutgers. There were placental mammals on Earth at the time of the great extinction of dinosaurs about 65 million years ago, Falkowski says. They were, however, tiny, limited creatures; ...

New lead reported in tumor angiogenesis

... tend to be mobile, shifting within the developing mass and possibly establishing tumor-to-endothelial cell contact to prompt angiogenesis. "We have some evidence that inflammatory factors, and even some infectious agents, can induce jagged1 expression," said Wang. "That's what we plan to study next." Th...
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(Date:5/15/2008)...DGE, Mass.--MIT engineers have improved the power ...rcent through technology that could help these env...a much broader market, particularly in portable el... also considerably less expensive than its convent...es. , Our goal is to replace traditional fuel-ce...
(Date:5/15/2008)...LA, CA - Now that high school biology students can...cribed into messenger RNA (mRNA), which is then tr...molecules, sending studentsand many scientistsscra...Institute for Biological Studies investigator Jose...ne issue of Developmental Cell, shows that the RNA...
(Date:5/15/2008)...s Institute researchers Karen Staehling-Hampton, P...Olivier Pourqui, Ph.D., Investigator, collaborated...t genes known to cause spinal mutations in chick a... in human patients with congenital vertebral abnor...n the Web site of the American Journal of Human Ge...
(Date:5/15/2008)...men hold empirical knowledge that tuna aggregate u..., pieces of wood, or even large marine mammals. Th...ion behaviour, but the past 20 years have seen pur...ssociated concentrations of fish. Fishermen cast o... FADs. An enormous purse-seine net, deployed in a ...
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(Date:5/16/2008)...CH, Fla., May 16 /PRNewswire-USNewswire/- "Huh, wh... by Americans, particularly our,children. More tha..., have,significant hearing loss and the numbers ar...y 100 school age children have some form of hearin...social and economic problem,is what led Kathlyn Ma...
(Date:5/16/2008)...ents Urban Health Institute with 10,000 Sensual O ...g at Playboy Mansion Fundraiser, LOS ANGELES, May...p-hop,and R & B artist J Kwon known best for his h...l be presenting the Urban Health Institute (UHI) w...over $50,000. The donation is,being made to promot...
(Date:5/16/2008)...RG, Pa., May 16 /PRNewswire-USNewswire/ -- Emergen...tunity to highlight the dedication,of Pennsylvania... become,trained EMS volunteers, according to state...ar,s theme, "EMS: Your Life is Our Mission," empha... it occurs, EMS is there to provide,immediate, lif...
(Date:5/16/2008)...s for Funds Focus on Millions of Children Still in.... Fund for UNICEF and The,Advertising Council toda...e,a series of national public service announcement...en Stiller, Nicole Ritchie, Joel Madden, David,Duc...elp survivors of the,Myanmar cyclone. The Ad Counc...
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