malformation

Cells from amniotic fluid used to tissue-engineer a new trachea

...iotic fluid provide enough fetal cells to repair a malformation in utero or after birth potentially, even years later, Fauza says. He envisions a future in which amniotic fluid is banked for everyone's use. "Fetal cells are the best cells you can have for tissue engineering," he says. "They grow very well, and ...

UCSD study finds anthrax toxins also harmful to fruit flies

...al when applied to fly larvae and can cause severe malformation in the wings of adult fruit flies--an effect that can also be understood as an interruption of another unrelated signaling process common to flies and humans. "We asked the simple question of whether anthrax toxins affecting mammals could act on th...

Cholesterol gets 'thumbs up' for role in digit development

...condition known as holoprosencephaly, a congenital malformation of the forebrain. Chiang is currently examining the role of cholesterol-modified Sonic hedgehog in the developing brain and spinal cord. "We are finding some surprises,"Chiang said, "suggesting that the function of cholesterol is different in the...

Matrilin-3 gene discovered to prevent onset of osteoarthritis

... disorder that begins in childhood and can include malformation of the hands, feet and knees and abnormal curvature of the spine. In this study, researchers knocked out matrilin-1 and -3 in mice in order to study their link to osteoarthritis. When matrilin-1 was knocked out, there was no apparent effect. When m...

New hereditary breast cancer gene discovered

...omen who have a predisposition for Saethre-Chotzen malformation syndrome," says Göran Stenman. By detailed mapping of families with Saethre-Chotzen syndrome, the Göteborg scientists have now found that women with this syndrome have an elevated risk of contracting breast cancer. Saethre-Chotzen is a syndrome t...