Loop in Biological News

Genetic switch potential key to new class of antibiotics

... of the mRNA's ribosome binding site binds to a loop of the riboswitch, the "lever" by which the ... to itself to form a double helix that ends in a loop like a lollipop. The current study revealed some surprising insights into how the loop end of the preQ1 riboswitch aptamer domain binds ...

Study reveals how viruses collectively decide the fate of a bacterial cell

... genomes inside a cell. The positive feedback loop was linked to the lysogenic pathway and the negative feedback loop was linked to the lytic pathway. With a single ... a certain threshold, the positive feedback loop associated with cI dominated, turning the switch ...

Rebuilding the evolutionary history of HIV-1 unravels a complex loop

... of the protein spike called the third variable loop (labeled V3). Protein components like V3 are ... 1,145 genetic sequences encoding the V3 loop to discover groups of amino acids that were ... co-evolving amino acids formed ties across the V3 loop like rungs on a ladder, corroborating models from ...

TGen helps promote cancer awareness for vast Navajo Nation

... a.m.-5 p.m. July 18 at the Navajo Nation Museum, Arizona 264 and Postal loop Road, in Window Rock. The first conference in October was an ... Advocacy Conference. Where: Navajo Nation Museum, Arizona 264 and Postal loop Road, Window Rock, Arizona. When: 8:30 a.m.-5 p.m. July 18. Who: Open to ...

Rice University study finds possible clues to epilepsy, autism

... on." Howlett's breakthrough was identifying the negative feedback loop that acts to maintain neuronal excitability at normal levels. "What we ... of its role in tumor formation." Discovering the negative feedback loop that keeps neurons stable was key, said Stern, but not the end of the ...

Rice lab finds molecular clues to Wilson disease

... of the protein is capped with a large, flexible loop. The purpose of the loop is unknown, but its shape is altered and more compact in the diseased form of the protein. "This implies that the loop has some importance, perhaps in regulation of ATP7B's activities, and we ...

Study: Future snowmelt in West twice as early as expected; threatens ecosystems and water reserves

... lead author on the paper, said the melting snow contributes to a feedback loop that accelerates warming. "Because snow is more reflective than the ... solar energy is absorbed by the ground, warming the surface. A feedback loop is created because the warmer ground then makes it more difficult for snow ...

Disabling mouse enzyme increases fertility

... consistently added to luteinizing hormone, which is part of a feedback loop between the pituitary, the reproductive organs and the liver. The loop cycles up and down over time, producing periodic peaks in other ...

Biophysical Society announces winners of 2008 Student Travel Awards

... University of Wisconsin-Madison, An intrasubunit Salt-Bridge Linking loop A and loop 2 is Critical for GABAA Receptor Activation. Paula A. Vivas, ...

Amazon forest shows unexpected resiliency during drought

... starts. That slowdown in plant growth would create a positive feedback loop -- as the forest shuts down more and more, it removes less and less carbon ... thus drawing down the levels of atmospheric CO2. That negative feedback loop would slow warming from greenhouse gases. Evolutionarily, the forest's ...

'Green' energy from algae

... Hence, energy from algae can be produced in a CO 2 -neutral manner contrary to conventional energy carriers. Apart from CO 2 -neutral closed loop management, algae have an-other advantage: Industrial CO 2 emissions may be used as a "re-source", as algae grow faster at high carbon dioxide ...

World's largest ocean observatory takes shape

... ROV, the team is lowering five 13-tonne nodes and more than 400 instruments and sensors to the seafloor where they are being attached to an 800-km loop of powered fibre-optic cable laid in 2007. Led by the University of Victoria, NEPTUNE Canada pioneers a new generation of ocean observation ...

Scientists examine perceptions of risk and the spread of disease

... professor at Arizona State University. "When people perceive risks, they alter their behavior, which in turn, alters the risk. It's a feedback loop between people, the pathogen, and the risk." Most current attempts to model the risks of emerging infectious diseases look at the disease itself ...

Scientists examine human behavior and the threat of disease

... professor at Arizona State University. "When people perceive risks, they alter their behavior, which in turn, alters the risk. It's a feedback loop between people, the pathogen, and the risk." Most current attempts to model the risks of emerging infectious diseases look at the disease itself ...

Researcher garners major award from NIH for further exploration into the mechanisms of obesity

... (MERIT) award from the National Institute of Diabetes and Kidney Diseases will provide long-term for his lab's investigation into the communication loop between fat cells and the brain, which Bartness has researched for the past 26 years with NIH support. "I am delighted to have received this ...

New research helps explain how connexin hemichannels are kept closed

... The report, along with a recent publication from Verselis et al. (3), provides new information about the conformational changes that occur within the loop gate. In addition, the concurrent unveiling of a high-resolution structure of a connexin channel has been a long-awaited and noteworthy development ...

Breast health center gives TGen new research opportunities

... Cancer Research Unit. The new center is located in John C. Lincoln's Medical Offices 3, 19646 N. 27th Ave., just southwest of Interstate 17 and loop 101, in northwest Phoenix. "Our new state-of-the-art medical equipment allows the earliest possible detection of breast cancers when survival ...

Scientists shed light on inner workings of human embryonic stem cells

... for the growth of tumors. The discovery is also expected to help with other diseases and injuries. The study describes nature's negative feedback loop in cell biology. "We have found an element in the cell that controls 'pluripotency,' that is the ability of the human embryonic stem cell to ...

ORNL, Southern Cal set sights on preventing blindness

... oxygen to the retina while avoiding the formation of potentially harmful chlorine," Greenbaum said. By using three electrodes and a feedback loop made possible by implanting a "ground" electrode behind the patient's ear, the research team is able to maintain constant pH in the area being ...

Missing piece of plant clock found

... to the part of plant DNA that controls a critical component of the morning loop. Further experiments demonstrated that CHE also binds to an evening loop protein providing the missing link. Pruneda-Paz and his co-authors "solve a major puzzle in our understanding of the plant clock," wrote C. ...

Methods for studying DNA repair and protein modification are featured in CSH Protocols

... ) has detailed a method for generating these structures in their article, "Assay for Human Rad51-Mediated DNA Displacement loop Formation." This reconstituted system provides researchers a biochemical means to dissect the mechanisms of the homologous recombination machinery. ...

Jupiter's shrinking red spot

... a wide range of practical applications in energy-generation devices, such as stationary power plants and utility burners. Davitian's talk, "Open loop Control of Self-Excited Transverse Jets," will be given at 5:15 p.m. on Sunday, November 23, 2008, in Room 002B of the San Antonio Convention Center. ...

Key to function of dinosaur crests found in brain structure

... bony crests on the heads of the duck-billed dinosaurs known as lambeosaurs. The structures contain incredibly long, convoluted nasal passages that loop up over the tops of their skulls. Scientists at the University of Toronto, Ohio University and Montana State University now have used CT-scanning ...

Brain structure provides key to unraveling function of bizarre dinosaur crests

... bony crests on the heads of the duck-billed dinosaurs known as lambeosaurs. The structures contain incredibly long, convoluted nasal passages that loop up over the tops of their skulls. Scientists at the University of Toronto, Ohio University and Montana State University now have used CT-scanning ...

Frost & Sullivan Recognizes AOptix Technologies for its Pioneering Contribution to Security through Noninvasive Biometrics

... recognition technology -- effectively "iris at a distance" -- provides an ideal solution." The company's iris recognition system employs closed loop control, or feedback, to automate the subject acquisition process and provide consistently high quality iris imaging. First, a wavefront sensor ...

Loneliness undermines health as well as mental well-being

... fewer close friends and confidants than those a generation ago. Cacioppo and Patrick also demonstrate how loneliness creates a feedback loop that reinforces social anxiety, fear and other negative feelings. By learning more about what underlies this experience, then learning to reframe ...

Biophysical method may help to recover hearing

... cochleas have been developed that are extremely close to the performance of the biological one, the integration of artificial cochleas into this loop is an extremely difficult micro-surgical task. In an attempt to circumvent this problem, the authors investigated the biophysics and bio-mechanics ...

Let the cat keep chasing the mouse

... the border to Belgium. A decisive factor for wildcat habitat proved to be the distance to human settlements: "The shy forest-dwellers making a large loop around settlements. Within a radius of one kilometre from settlements they occur more rarely and even with individual houses or roads they still keep ...

Closing the hydrogen economic loop

... introduction of the Ovonic nickel metal hydride battery used in hybrid vehicles. Reversible storage of hydrogen in a solid hydride permits the entire loop of hydrogen generation, storage and use, to be carried out now, rather than at some distant point in the future. Ovshinsky suggests that that despite ...

Scripps Oceanography Research pegs ID of red tide killer

... to the fact that red tide dinoflagellates dont exist in isolation of other parts of the marine food web. Bacteria and other parts of the microbial loop feed on the organic matter released by the dinoflagellates and in turn the dinoflagellates are known to feed on other cells (including bacteria) when ...

Analysis of RNA role in spreading disease advances study of damaging plant infections

... RNAs, so that means that what we learned can be applied to other types of RNA. So far, the researchers have discovered that a change to almost any loop will slow or eliminate replication, except for one loop. In that case, when disrupted, it instead causes an increase in RNA duplication. A few loops ...

Marine bacteria's mealtime dash is a swimming success

... pass it on to larger animals and prevent it from dropping out of the marine food web. But quantifying the importance of bacteria in the microbial loop has been difficult, because creating a realistic microenvironment wasnt possible until recently. You can hope to study an organisms behavior only ...

Stanford researchers make first direct observation of 3-D molecule folding in real time

... then let it curl up again. In the Feb. 1 issue of Science, their paper, of which Block is senior author, describes the development of every loop and fold in one particular RNA riboswitch, and the energy it takes to form or straighten each one-an unprecedented achievement that opens the door ...

Penn researchers find monkeys able to fend off AIDS-like symptoms with enhanced HIV vaccine

... those findings in a larger, non-human primate species. In this study, the group of macaques that was injected with the vaccine containing a loop of DNA enabling them to make IL-15 developed no signs of AIDS-like symptoms when exposed to live SHIV, compared to four animals in the control group ...

Scientists unveil structure of molecular target of many drugs

... and co-workers at Stanford University turned to protein engineering. To overcome problems with the proteins floppiness, they replaced a flexible loop with a more rigid protein structure. Raymond Stevens and co-workers of The Scripps Research Institute managed to coax the intransigent proteins into ...

'Jumping genes' could make for safer gene delivery system

... and gene therapists have two proven options: a virus, which can effectively ferry genes of interest into cells, and a plasmid, an engineered loop of DNA that can do the same thing, albeit usually only on a short-term basis. The catch is that viruses can be infectious and some types of ...

Study finds blocking angiogenesis signaling from inside cell may lead to serious health problems

... cell, Iruela-Arispe said. When there is no VEGF signaling inside the cell, the endothelial cells die. The intracellular part of the VEGF signaling loop is required for cell survival. This is the first demonstration that intracellular signaling is an important event. It had been unclear why some ...

Nobel Laureate finds 'elegant' explanation for DNA transcribing enzyme's high fidelity

... that a portion of the enzyme known as the trigger loop acts like a “trap door,?swinging beneath a ... leave another side chain in the trigger loop precisely positioned, such that it may literally ... those critical interactions fail. The trigger loop mechanism therefore couples NTP recognition and ...

Study finds how organs monitor themselves during early development

... terms this question could involve a feedback loop that lets the body check in on itself and then ... Medicine have unraveled the signals in a feedback loop governing ovarian development. This work has been ... Tapping into that kind of powerful feedback loop could help treat many kinds of disorders and show ...