linker

Chemists identify immune system mechanism for methamphetamine binges

...rug molecules," Janda says. "Glycation acts like a linker that allows [the methamphetamine] to be displayed to the immune system, triggering a vaccine-like reaction." Just as a vaccine is able to remove invading pathogens by using antibodies to the pathogen, antibodies to methamphetamine attack and begin t...

Engineers improve plastic's potential for use in implants by linking it to biological material

...o. Schmidt's laboratory intends to study T59 as a linker to other molecules in the future, possibly including vascular endothelial growth factor, which stimulates the growth of new blood vessels. In addition, they will use the bacteriophage analysis approach, called high-throughput combinatorial screening,...

Quantum dots provide a faster, more sensitive method for detecting respiratory viral infections

...ry viruses have been identified and can be used as linker molecules. Such a test would be able to diagnose more than 90 percent of all the cases of viral respiratory infection, he says. The existence of such a test could encourage the development of improved therapies for respiratory viruses, Crowe says. W...

NYU chemists use computer simulation to enhance understanding of DNA transcription

...e results revealed that in a low-salt environment, linker DNAs in the array were repelled, preventing array ... However, under high-salt conditions, screening of linker DNA repulsion allows close contacts and attraction between nucleosomes, allowing the array to fold. ...

'Smart' nanoprobes light up disease

...ith a unique NIR optical signature, to an index of linker proteases. "There is currently a critical need for methods to simultaneously image the activity of multiple proteases in vivo," said Drezek. "This is important not only for early detection of several diseases, but perhaps more significantly, in unde...

ASU researchers 'wire' DNA to identify mutations

...asurement and repeat." In the technique, chemical linker groups that form a tight bond with gold electrodes are attached to the ends of DNA. A drop of a DNA solution is then placed between the two electrodes. The DNA sticks to the surface of the electrodes spontaneously. As the tip is pulled away and the...

Nanoparticle assembly enters the fast lane

...gid, double-stranded DNA, which forces interacting linker segments of DNA to extend away from the gold surface, allowing for more efficient assembly. "By using properties of DNA, we can increase assembly kinetics, or speed, by relatively simple means without a lot of synthetic steps," Maye said. The...

Scientists identify molecular cause for one form of deafness

...lls. F-actin is organized into bundles by espin, a linker protein found in sensory cells, including cochlear hair cells. Genetic mutations in espin's F-actin binding sites are linked to deafness in mice and humans. "We found the structure of the bundles changes dramatically when normal espin is replaced w...