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limb in Biological News

Brain-computer interface, developed at Brown, begins new clinical trial

... dystrophy, amyotrophic lateral sclerosis (ALS) or limb loss turn their thoughts into actions, restoring ... signals associated with the intent to move a limb can be "decoded" by a computer in real time and ... on a computer screen, controlling a prosthetic limb or a robotic arm, controlling functional ...

Embryology study offers clues to birth defects

... clarified the role that retinoic acid plays in limb development. The study showed that retinoic acid ... corrects longstanding misconceptions about limb development and provides new insights into congenital limb defects. The study was published online in the ...

Grouping muscles to make controlling limbs easier

... have shown that it could be possible to control a limb by stimulating groups of muscles rather than ... shows that researchers can control the limb using muscle groups just about as well as if they ... idea that the body's nervous system controls a limb using muscle groups, or "synergies," has been a ...

UF scientist tapped by Howard Hughes Medical Institute to pursue 'best ideas'

... chick embryos, a classic scientific model of limb development. At University College London, he discovered that the embryonic master switch for limb formation was a multifunctional protein called ... similarities between the processes that control limb development and those that regulate development ...

Promising 3-year data: Saving limbs with drug-eluting stents

... Calif. (March 10, 2009)Attempts to treat critical limb ischemia in peripheral arterial disease (PAD) ... encouraging news for PAD patients with critical limb ischemia. The smaller blood vessels below the ... treatment of PAD patients with critical limb ischemia," he added. An interventional ...

Motor nerve targeting to limb muscles is controlled by ephrin proteins

... a family of proteins present in the developing limb control nerve targeting from the spinal cord to ... which nerves extend from the spinal cord to the limb to connect to either flexor muscles (i.e. biceps ... targets by a protein present in the developing limb (ephrin-A). Using chick and mouse embryos as ...

Thumbs up -- a tiny ancestral remnant lends developmental edge to humans

... influence the molecular machinery to yield human limb and thumb development patterns. The study ... the human sequence enhances gene expression in limb and braina gain of function. The next ... to uniquely human aspects of digit and limb patterning," Rubin said. "We suspect the gain of ...

Restless legs syndrome affects nearly 2 percent of US/UK children

... associated with another condition, periodic limb movement disorder, in which a persons legs jerk during sleep. Some people with periodic limb movement disorder also have RLS. Others lack the ... children with RLS. A child who had periodic limb movements during sleep and no other symptoms of ...

Reading the brain without poking it

... the thoughts to audible words. For people who have lost a limb or are paralyzed, "this device should allow a high level of control over a prosthetic limb or computer interface," Greger says. "It will enable amputees or people ...

Resilin springs simplify the control of crustacean limb movements

... Animals can simplify the brain control of their limb movements by moving a joint with just one muscle that operates against a ... that it is used to simplify the sensory and motor control systems at a limb joint." The limbs studied, called maxillipeds, move rhythmically to ...

Society of Interventional Radiology hosts 34th annual scientific meeting

... are available. Seeing the Promise of Drug-Eluting Stents for Critical limb Ischemia Interventional radiologists are helping peripheral arterial disease (PAD) patients with critical limb ischemia avoid amputation by exploring the treatment of the smaller blood ...

Single adult stem cell can self renew, repair tissue damage in live mammal

... its differentiated descendants restored lost function to mice with hind limb muscle tissue damage. The adult stem cells used in the study, conducted ... "nude" mice whose muscle satellite cells had been wiped out in a hind limb by irradiation. The mice would only be able to repair injury if the ...

New CU-Boulder study shows diversity decreases chances of parasitic disease

... tree frogs reduce their chances of parasitic infections known to cause limb malformations has strong implications for the benefits of biodiversity on ... the parasitic trematodes -- tiny worms whose larvae burrow into tadpole limb regions and disrupt normal leg development -- 40 percent of the emerging ...

Nutrient pollution drives frog deformities by ramping up infections, says CU-Boulder study

... as cercariae, can kill or deform a single tadpole by burrowing into their limb regions and disrupting normal leg development, he said. A single infected ... disease, the researchers are now exploring how nutrient pollution and limb malformations contribute to the pattern, Johnson said. ...

Knee injuries may start with strain on the brain, not the muscles

... to tear this ligament than men while playing the same sport. However, the study showed that men and women showed significant changes in lower limb mechanics during unanticipated single leg landings. Again, the findings point to the brain, McLean says. During testing, a flashing light cued ...

CWRU receives $5 million from Ohio Third Frontier Commission

... company from Marc Penn (CC), will develop its lead drug product, stromal cell derived factor 1 (SDF-1), through a Phase I clinical trial for critical limb ischemia. Emerging programs With further refinement of already established proof of concept, the following programs could mature into ...

March of Dimes awards $250,000 prize to scientists unraveling the causes of muscular dystrophy

... by the nine forms of muscular dystrophy and other related neuromuscular disorders. Among this group are facioscapulohumeral muscular dystrophy and limb girdle muscular dystrophy, as well as childhood conditions such as Duchenne and Becker muscular dystrophies and congenital muscular dystrophy. The ...

Research links evolution of fins and limbs with that of gills

... embryonic skates (a living relative of sharks that has gill rays) responds to treatment with the vitamin A derivative retinoic acid in the same way a limb or fin skeleton does: by making a mirror image duplicate of the structure as the embryo develops. According to the researchers, the genetic circuitry ...

Register now for the Society of Interventional Radiology's 34th Annual Scientific Meeting

... health: making childbirth safer Finding that age doesn't matter: AV fistulas and dialysis Seeing the promise of drug-eluting stents: critical limb ischemia Recommending treatment for "Silent Killer": abdominal aortic aneurysm Visit www.SIRmeeting.org to register online (free), view ...

Transplanted fat cells restore function after spinal cord injury

... recovery after spinal cord injury (SCI)," said Ohta. "Transplanting DFAT cells into SCI rats significantly promoted the recovery of their hind limb function." "These studies demonstrate the ability to obtain stem cells from a patient's own fat that can help repair injury to the spinal cord," ...

HJF nursing specialist wins prestigious Celina Field Cargiver Award

... hospital's policies on pain management through the creation of a Pain Process Improvement Team. Most of Rupprecht's patients have experienced severe limb injuries or amputations. Rupprecht also created and leads the Pain Management Task Force, which trains hospital staff on the ever-changing issue ...

Swamping bad cells with good in ALS animal models helps sustain breathing

... The new work supports the hypothesis that artificially outnumbering unhealthy cells with healthy ones in targeted parts of the spinal cord preserves limb strength and breathing and can increase survival. An account of the work appears online this week in Nature Neuroscience . Two parts of the ...

Reproducing early and often is the key to rapid evolution in plants

... such hypotheses are based on less than 50 species in total," said Yale graduate student and lead author Stephen Smith . For each branch on each limb of the "tree," the researchers calculated the rate of molecular evolution by determining the number of DNA nucleotide substitutions per site per ...

Galloping and breathing at high speed

... or racing. The researchers focused their efforts on understanding why this occurs. They found that two principal muscular factors in the fore limb guide a horse's forward movement. The first is the springy "pogo-stick" quality of the superficial digital flexor tendon, which provides the ...

Taking the next step toward advanced artificial limbs

... limbs that are connected to the nervous system so they can be controlled directly by the brain and provide sensory feedback to the brain, such as limb orientation, temperature of surfaces, and so on. Stephen Lambert, research associate professor with BEI, will direct basic science studies needed ...

Combining advanced medical and information technologies offers pathway to lower health care costs

... underscored by Dr. David G. Armstrong, DPM, PhD, Professor of Surgery, University of Arizona College of Medicine and Director of the Southern Arizona limb Salvage Alliance (SALSA), a noted expert on diabetes care, who said that the current expenditures for caring for the feet of people with diabetes ...

Gene enhancer in evolution of human opposable thumb

... far the most striking candidate. Remarkably, HACNS1 was found to play a unique human-specific gene-activating role in a region of the developing limb that eventually forms the junction of the wrist and thumb, and also extends partially into the developing thumb. A similar, though weaker activating ...

NIH EUREKA award funds research at WPI aimed at turning adult skin cells into stem-like cells

... a ball of undifferentiated cells that in amphibians forms from cells that remain at the site of an amputation. It is capable of regrowing the missing limb by forming all of the required tissue typesskin, muscle, bone, connective, and nerve. Mammals cannot generate blastemas, but instead heal injuries by ...

Technique used in human ankle injuries modified to treat dogs' knees

... for the Tightrope CCL method to be feasible. In addition, dogs that cannot follow a physical rehabilitation protocol after surgery and dogs with limb deformities are not candidates for this technique. The 10- to 12-week rehabilitation period is very important for any surgical technique for CCL ...

Satellites illuminate pollution's influence on clouds

... we can see the clouds every day and we're getting confirmation on a global scale that we have an issue here." Jiang's team used the Microwave limb Sounder on the A-Train's Aura satellite to measure the level of carbon monoxide in clouds. The presence of carbon monoxide implies the presence of ...

Key molecule discovered in Venus's atmosphere

... off. The band of atmosphere in which the glowing hydroxyl molecules are located is very narrow; it is only about 10 km wide. By looking at the limb of the planet, Venus Express looked along this faint atmospheric layer, increasing the signal strength by about 50. Hydroxyl is thought to be ...

Accelerometer backpacks aid study of gliding behavior in the 'flying' lemur

... lemurs as well as humans. Common throughout Southeast Asia, the colugo looks like a very large squirrel with membranous skin stretching from each limb and even between its toes to catch the wind and work as a parachute. When fully spread, the skin flaps reach the size of a large doormat. "This ...

Cell Therapy for Cardiovascular Diseases

... mechanism by which bone marrow cells help patients with acute myocardial infarction Bone marrow-derived stem cells for patients with critical limb ischemia, presented by both Drs. Berthold Amann and Brian Annex Transplantation of bone marrow stem cells for persistent, refractory angina, ...

Top scientists meet for global conference on stem cell therapy for cardiovascular diseases

... by which bone marrow cells help patients with acute myocardial infarction Bone marrow-derived stem cells for patients with critical limb ischemia, presented by both Drs. Berthold Amann and Brian Annex Transplantation of bone marrow stem cells for persistent, refractory ...

Fourth Annual International Conference on Cell Therapy for Cardiovascular Diseases

... cell infusion in patients with heart attack, presented in detail here by Dr. Hyo-Soo Kim Bone marrow-derived stem cells for patients with chronic limb ischemia, presented by Dr. Brian Annex Transplantation of bone marrow stem cells for persistent, refractory angina, presented and discussed by ...

Massive microRNA scan uncovers leads to treating muscle degeneration

... Institute, was senior investigator. The disorders include the muscular dystrophies (Duchenne muscular dystrophy, Becker muscular dystrophy, limb girdle muscular dystrophies, Miyoshi myopathy, and fascioscapulohumeral muscular dystrophy); the congenital myopathies (nemaline myopathy); and the ...

NASA keeps eye on ozone layer amid Montreal Protocol's success

... Bhartia, project scientist for the mission. In addition, measurements from the Stratospheric Aerosol and Gas Experiment, along with the Microwave limb Sounder and the Halogen Occultation Experiment aboard the Upper Atmospheric Research Satellite, were important to scientists' understanding of ozone. ...

Mice stressed in simulated weightlessness show organ atrophy

... Kathryn Wang, a co-author on the PNAS paper, had previously conducted experiments in which the mouse was positioned in such a way as to produce hind limb unloading. This simulated weightless condition produced OPN-dependent bone loss in the hind limbs and provided a potential testing ground for ...

Conquest of land began in shark genome

... of fingers and toes, Cohn said. Until now it was thought these mutations were affecting a relatively recent innovation in the genetic process of limb development. Our results show that this phase of Hox expression is much more ancient and suggest that if the origin of digits involved a prolonged ...
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