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libraries in Biological News

Using combinatorial libraries to engineer genetic circuits advances synthetic biology

... researchers to develop a technique that couples libraries of diversified components with computer modeling ... a simple synthesis technique to create component libraries for synthetic biology. Each version covered a ... genetic timer using a promoter from each of their libraries and, over time, tracked its behavior. Based on ...

Broad Institute awarded grant to develop chemical probes for human biology and disease

... to receive funding under the Molecular libraries and Imaging Initiative, one of the NIH Roadmap ... Comprehensive Screening Centers in the Molecular libraries Probe Production Centers Network (MLPCN), where ... PubChem, which is associated with the Molecular libraries and Imaging Initiative. Follow-up work, including ...

New 3-D test method for biomaterials 'flat out' faster

... was the collaborators success in making so-called libraries of miniature porous scaffolds that are bone-like ... but related investigations, each one using libraries of 36 incrementally varying scaffolds and 12 ... multiply and to adhere to scaffolds. The scaffold libraries were made by blending varying proportions of two ...

U. of I. librarian launches comprehensive Web database of field guides

... the database exclusively, visiting more than 75 libraries and bookstores over the course of six months. ... in late January, she took free time to visit libraries and bookstores on the hunt for new titles. Since ... Language also can be a problem, she said. libraries in the U.S. dont collect as many books in ...

New $11 million center to speed production of new compounds for drug discovery

... joined forces to develop new ways of building state-of-the-art chemical libraries that will help identify new compounds for future drug development and ... specifically for their ability to kill cancer cells, but the chemical libraries that the Chicago Tri-Institutional Center produces will be readily ...

Using novel tool, UD researchers dig through cell 'trash' and find treasure

... are recognizable by the high level of the specific cut site in the libraries generated by the UD technique, they can be distinguished from molecules ... by synthesis (SBS). The application of this technique to the UD-made libraries produced a distinct "signature" for each cleaved messenger RNA molecule, ...

Pictometry and First American Combine Accurate Parcel Addressing With 3-D Like Intelligent Images(TM)

... International Corp., a leading provider of geo-referenced aerial image libraries whose proprietary technology is used globally to capture oblique image ... International Corp. is a leading provider of geo-referenced, aerial image libraries and related software. Pictometry has captured over 50 million digital ...

Scripps Research Institute awarded patent for remarkable chemical technology

... benefits. To identify potential pharmaceuticals, researchers often test libraries of thousands or even millions of molecules to identify those that might ... both types of molecules can be combined, allowing bonding to form molecule libraries that can then be run through these disease tests. Using copper-catalyzed ...

Cornell researcher seeks clues to how tuberculosis infects cells

... is to develop these bacterial fitness readouts to screen small molecule libraries for compounds that will kill M. tuberculosis inside the macrophage," ... Cornell does not have either the instrumentation or the chemical libraries necessary to do this work, so I am trying different, private funding ...

A complete view of complexity in science and society in a new authoritative reference work

... sciences to applications in physical sciences, engineering, biomedicine, economics and social sciences. The Encyclopedia will meet the needs of libraries in academia, government laboratories and industries such as pharmaceuticals, computer hardware and software, aerospace, telecommunications and ...

Academy Library accepted to prestigious Biodiversity Heritage Library

... been accepted as a member of the prestigious Biodiversity Heritage Library. The BHL is a group of 12 natural history museum libraries, botanical libraries and research institutions worldwide dedicated to digitizing the published literature on biodiversity in order to preserve it and to make it more ...

Springer launches SpringerImages

... and books, including Open Access content. The database contains photos, graphs, histograms, tables and figures, and is available by subscription to libraries and research institutions. SpringerImages allows users to search fast, broadly and accurately through captions and keywords (both author-provided ...

American Journal of Botany named a top 10 most influential journal of the century

... The Special libraries Association (SLA) has selected the American Journal of Botany as one of the 10 most influential journals of the past 100 years in the field of ...

'Annals of the ESA' selected as one of 100 most influential journals

... A poll conducted by the BioMedical & Life Sciences Division (DBIO) of the Special libraries Association (SLA) to identify the 100 most influential journals of biology and medicine over the last 100 years listed Annals of the Entomological ...

3 prominent Cell Press journals named among the 100 most influential journals in past 100 years

... over the last century. The "Journal of the Century" and the Top Ten journal titles will be announced at the Centennial Conference of the Special libraries Association on June 16th in Washington, D.C. "We are honoured to be recognized by the SLA for influence and impact in biology, on behalf of Cell ...

Three prominent Cell Press journals named among the 100 most influential journals in past 100 years

... over the last century. The "Journal of the Century" and the Top Ten journal titles will be announced at the Centennial Conference of the Special libraries Association on June 16th in Washington, D.C. "We are honoured to be recognized by the SLA for influence and impact in biology, on behalf of Cell ...

New high-throughput screening technique makes probing puzzling proteins possible

... library of compounds for inhibitory activity. Such readout techniques do not lend themselves to rapid automation, limiting screening applications to libraries of only a couple hundred or so molecules. Given that academic and corporate researchers alike now rely on high-throughput screening of up to hundreds ...

Protein is key to embryonic stem cell differentiation

... also demonstrated small interfering RNAs in hESCs reduce Shp2 expression and subsequent cell differentiation. Feng and colleagues screened chemical libraries and identified a small-molecule inhibitor of Shp2 that, in small doses, partially inhibits differentiation in both mESCs and hESCs. Taken together, ...

Engineers create intelligent molecules that seek-and-destroy diseased cells

... its first iGEM team this year. Endy will also discuss his efforts, along with colleagues, to start fabrication facilities focused on churning out libraries of open-access biological parts and the resulting implications for biological engineering. ...

New open-source software permits faster desktop computer simulations of molecular motion

... said Andy Keane, general manager, GPU Computing at NVIDIA. "We'll continue our close collaboration with Stanford on OpenMM so that current and future libraries can maximally leverage the power of the GPU." OpenMM incorporates specially developed algorithms that allow MD software to take full advantage of ...

Finalists announced in the Elsevier Grand Challenge

... but also with the discussions that resulted both with the judges and the other teams," added Challenge Judge David Rosenthal, of Stanford University libraries in Palo Alto. Finalist Sean O'Donoghue (Research Scientist, EMBL, Germany) agreed: "All participants of the meeting this week are already ...

Scientists can now differentiate between healthy cells and cancer cells

... uniquely positioned for this discovery platform, and this was the missing ingredient - we have one of the best screening/robotic platforms, chemical libraries and expertise in professors Eric Brown and Gerry Wright, who have discovered molecules to combat infectious disease. Now we can combine it all. This ...

Columbia University scientist devises new way to more rapidly generate bone tissue

... in bone more rapidly than when either type of stem cell was used alone. The work by Jeremy Mao, DDS, Ph.D., published today in the Public libraries of Science, takes a new approach: rarely have mesenchymal and hematopoietic cells been delivered in combination for the healing of defects and the ...

Scripps Florida scientists awarded $1.5M to fight major water and food parasites

... What makes these proteases attractive as therapeutic targets is that they are found in a number of different parasites, and that synthetic inhibitor libraries have already been developed against this enzyme family. As a result, a wealth of inhibitor leads already exist, many of which have been subject ...

Deprived of a sense of smell, worms live longer

... quickly. In addition, the worms' genome has been sequenced and extensively studied. The scientists' strategy has been to expose the roundworms to libraries of chemicals to identify compounds that delay aging and extend their lives. That approach led to the unexpected result that some human ...

UT Southwestern researcher awarded Gates Foundation grant for novel vaccine development

... limited in their effectiveness to a particular strain or subspecies of a given virus, but rather recognize all viruses of each type. Furthermore huge libraries of peptoids can be made and screened," said Dr. Vitetta, who holds the Scheryle Simmons Patigian Distinguished Chair in Cancer Immunobiology. ...

Caltech engineers build firast-ever multi-input 'plug-and-play' synthetic RNA device

... together, then just as easily swap out the components for other ones and get a completely different kind of computation. We could generate huge libraries of well-defined sensors and assemble many different tailored devices from such component libraries." Although the work in the Science paper was ...

Novel publishing approach puts textbook in more hands

... from parts of Africa, South America, and Asia. The audience is also educationally dispersed: the book is referenced in Wikipedia, university libraries all over the world list and link to the electronic book, and major Internet search engines index the content." While the first edition focused ...

Text focuses on diagnosing infections in immunocompromised patients

... procedures that can be applied to everyday patient care challenges. "We hope this book will fill a void in many health care providers' libraries and contribute positively to the care of these increasingly complex patients. By sharing this information and working effectively together with a ...

Burnham researcher awarded $8 million grant

... to the disease process and the chemically-modified proteins may serve as biomarkers for disease progression. Our goal is to screen chemical libraries to find compounds that prevent free-radical induced changes to these Parkinson's-related proteins." The new NIH-designated CNS Institute, formed ...

Sony Cyber-shot Cameras Get Smarter

... auto focus and zoom functions are available, as well as the ability to take a limitless number of shots. Not One, But Two Photo libraries in Your Pocket The T700 camera is ideal for anyone who wants to have what Lubell calls "bragging" photos of their kids, pets, vacation or sports ...

Consortium develops new method enabling routine targeted gene modification

... strands within the binding site. Currently available methods for generating ZFNs are either inefficient or involve constructing and analyzing huge libraries of zinc-finger peptides, a task that exceeds the capabilities of all but a handful of laboratories in the world. First author Morgan L. Maeder of ...

Michael J. Fox Foundation awards $2.4M for validation of therapeutic targets for Parkinson's

... Stephen F. Traynelis, PhD, of Emory University was funded under MJFF's Community Fast Track 2005 initiative to screen small-molecule compound libraries for molecules that inhibit a certain type of brain receptor called the NR2D-containing NMDA receptor in the basal ganglia, a part of the brain ...

Genetic Engineering & Biotechnology News reports on novel hit-to-lead drug discovery

... that can often provide valuable insight into complex disease models. Pharmacopeia's screening platform is based on its ECLiPS (encoded combinatorial libraries on polymeric support) technology. Three steps are involved in the firm's screening process. A primary high-throughput approach screens eluate from ...

New whitepaper offers options for university implementation of NIH policy

... Cambridge, MA February 29, 2008 SPARC (the Scholarly Publishing and Academic Resources Coalition), Science Commons, and the Association of Research libraries (ARL) have jointly released a white paper to help university and medical school administrators ensure their institutions comply with public access ...

Professor's video series explains all facets of Earth

... Virginia, produces How the Earth Works. Wysession has also written a 250-page print book to accompany the lectures. His audience includes schools and libraries but mostly consists of individual professional people - doctors, lawyers, engineers - who tend to seek knowledge in areas of their curiosity, but not ...

Team IDs weakness in anthrax bacteria

... for the next generation of antibiotics, said Lippard. With this knowledge in hand, the researchers are now using the fluorescent probe to screen libraries of chemicals for compounds that could potentially interfere with the bacterium's ability to synthesize NO, said Lippard. Such compounds could ...

Humana Press journals now available on SpringerLink

... along with more than 1,500 peer-reviewed Springer journals and more than 22,000 eBooks. Beginning with the subscription year 2008, libraries and research institutions may purchase Humana Press journals through Springer. All issues previously available on the Humana Press platform are now ...

Elevated carbon dioxide changes soil microbe mix below plants

... to isolate regions of genetic material known to be highly species-specific, sequenced these regions, and compared them with genetic sequence libraries of known bacteria, eukaryotic microbes (those with nuclei, such as fungi and protozoa), and archaea, a group of microbes that are genetically ...

Moss genome shows how plants invaded the land and learned to survive heat and drought

... said Mishler, who is director of the University and Jepson Herbaria, two collections of pressed plants housed together along with research labs, libraries and archives at UC Berkeley. "We have been looking for years at all levels, from the organism down to the molecular level, at how mosses do this, ...
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Breaking Biology News(10 mins):Scientists call for investigation of mysterious cloud-like collections in cells 2Week-long meeting on naming algae, fungi, and plants recorded for posterity 2New tuberculosis blood test in children is reliable and highly specific 2
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